'God protects us from death through faith and science: a qualitative study on the role of faith leaders in combating the COVID-19 pandemic and in building COVID-19 vaccine trust in Addis Ababa, Ethiopia
Conclusions
This research showed that faith leaders played crucial roles in encouraging vaccine use but were limited in their persuasion power because of intense rumours and misinformation. Empowering faith leaders with the latest vaccine evidence needs to be prioritised in the future. (Source: BMJ Open)
Source: BMJ Open - April 22, 2024 Category: General Medicine Authors: Yibeltal, K., Workneh, F., Melesse, H., Wolde, H., Kidane, W. T., Berhane, Y., Herzig van Wees, S. Tags: Open access, Public health, COVID-19 Source Type: research
Who won?
Families, Systems, & Health, Vol 42(1), Mar 2024, 139; doi:10.1037/fsh0000844This poem describes the ugly face of misinformation and lies-spewing bile as COVID shook us and humanity came undone. Vaccines were rejected and lockdowns were broken. We barely withstood. Who won? No one. (PsycInfo Database Record (c) 2024 APA, all rights reserved) (Source: Families, Systems, and Health)
Source: Families, Systems, and Health - April 22, 2024 Category: International Medicine & Public Health Source Type: research
BBIBP-CorV vaccine effectiveness against COVID-19 in patients aged 60 years and older during the Delta-dominant period in the Federation of Bosnia and Herzegovina, a test-negative case-control study
In this study, we estimated the vaccine effectiveness (VE) of complete primary series BBIBP-CorV vaccine against COVID-19 in patients aged 60 years and older, during the Delta-dominant period, using a test-negative case-control design. Surveillance sites were 11 primary health care centers (PHC) collecting patient data from October 1, 2021, to January 4, 2022, retrospectively according to a common protocol. In total, we included 1711 participants in the analysis: 933 cases and 778 controls. Of the 933 cases, 508 (54.4 %) had mild and 425 (45.6 %) had moderate to severe disease presentation. We observed no effectiveness aga...
Source: Vaccine - April 21, 2024 Category: Allergy & Immunology Authors: Sanjin Musa Lore Merdrignac Sinisa Skocibusic Rozalija Nedic Seila Cilovic-Lagarija Esther Kissling Source Type: research
A live attenuated influenza B virus vaccine expressing RBD elicits protective immunity against SARS-CoV-2 in mice
In this study, we constructed an IBV-based vector vaccine by inserting a receptor-binding domain (RBD) into a non-structural protein 1 (NS1)-truncated gene (rIBV-NS110-RBD). Subsequently, we assessed its safety, immunogenicity, and protective efficacy against SARS-CoV-2 in mice, and observed that it was safe in a mouse model. Intranasal administration of a recombinant rIBV-NS110-RBD vaccine induced high levels of SARS-CoV-2-specific IgA and IgG antibodies and T cell-mediated immunity in mice. Administering two doses of the intranasal rIBV-NS110-RBD vaccine significantly reduced the viral load and lung damage in mice. This ...
Source: Virus Research - April 21, 2024 Category: Virology Authors: Zhenfei Wang Weiyang Sun Dongxu Li Yue Sun Menghan Zhu Wenqi Wang Yiming Zhang Entao Li Feihu Yan Tiecheng Wang Na Feng Songtao Yang Xianzhu Xia Yuwei Gao Source Type: research
BBIBP-CorV vaccine effectiveness against COVID-19 in patients aged 60 years and older during the Delta-dominant period in the Federation of Bosnia and Herzegovina, a test-negative case-control study
In this study, we estimated the vaccine effectiveness (VE) of complete primary series BBIBP-CorV vaccine against COVID-19 in patients aged 60 years and older, during the Delta-dominant period, using a test-negative case-control design. Surveillance sites were 11 primary health care centers (PHC) collecting patient data from October 1, 2021, to January 4, 2022, retrospectively according to a common protocol. In total, we included 1711 participants in the analysis: 933 cases and 778 controls. Of the 933 cases, 508 (54.4 %) had mild and 425 (45.6 %) had moderate to severe disease presentation. We observed no effectiveness aga...
Source: Vaccine - April 21, 2024 Category: Allergy & Immunology Authors: Sanjin Musa Lore Merdrignac Sinisa Skocibusic Rozalija Nedic Seila Cilovic-Lagarija Esther Kissling Source Type: research
A live attenuated influenza B virus vaccine expressing RBD elicits protective immunity against SARS-CoV-2 in mice
In this study, we constructed an IBV-based vector vaccine by inserting a receptor-binding domain (RBD) into a non-structural protein 1 (NS1)-truncated gene (rIBV-NS110-RBD). Subsequently, we assessed its safety, immunogenicity, and protective efficacy against SARS-CoV-2 in mice, and observed that it was safe in a mouse model. Intranasal administration of a recombinant rIBV-NS110-RBD vaccine induced high levels of SARS-CoV-2-specific IgA and IgG antibodies and T cell-mediated immunity in mice. Administering two doses of the intranasal rIBV-NS110-RBD vaccine significantly reduced the viral load and lung damage in mice. This ...
Source: Virus Research - April 21, 2024 Category: Virology Authors: Zhenfei Wang Weiyang Sun Dongxu Li Yue Sun Menghan Zhu Wenqi Wang Yiming Zhang Entao Li Feihu Yan Tiecheng Wang Na Feng Songtao Yang Xianzhu Xia Yuwei Gao Source Type: research
Obesity Differs from Diabetes Mellitus in Antibody and T Cell Responses Post COVID-19 Recovery
This study aims to investigate the humoral and cellular immune responses to SARS-CoV-2 in adult COVID-19 survivors with obesity and DM in Bangladesh. In this cross-sectional study, SARS-CoV-2-specific antibody and T cell responses were investigated in 63 healthy and 75 PCR-confirmed COVID-19 recovered individuals in Bangladesh, during the pre-vaccination first wave of the COVID-19 pandemic in 2020. In COVID-19 survivors, SARS-CoV-2 infection induced robust antibody and T cell responses, which correlated with disease severity. After adjusting for age, sex, DM status, disease severity, and time since onset of symptoms, obesi...
Source: Clinical and Developmental Immunology - April 20, 2024 Category: Allergy & Immunology Authors: Mohammad Ali Stephanie Longet Isabel Neale Patpong Rongkard Forhad Uddin Hassan Chowdhury Jennifer Hill Anthony Brown Stephen Laidlaw Tom Tipton Ashraful Hoque Nazia Hassan Carl-Philipp Hackstein Sandra Adele Hossain Delowar Akther Priyanka Abraham Shreba Source Type: research
Are the 7C psychological antecedents associated with COVID-19 vaccine behaviours beyond intentions? A cross-sectional study on at-least-one-dose and up-to-date vaccination status, and uptake speed among adults in France
CONCLUSION: This study demonstrates that the 7C not only explain vaccine intention, but also vaccine behaviours, and underpins the importance of developing vaccine promotion strategies considering the 7C antecedents.PMID:38643038 | DOI:10.1016/j.vaccine.2024.04.024 (Source: Vaccine)
Source: Vaccine - April 20, 2024 Category: Allergy & Immunology Authors: Ga ëlle Lièvre Jonathan Sicsic Simon Galmiche Tiffany Charmet Arnaud Fontanet Judith E Mueller Source Type: research
Cutaneous adverse reactions associated with COVID-19 vaccines: Current evidence and potential immune mechanisms
Clin Immunol. 2024 Apr 18:110220. doi: 10.1016/j.clim.2024.110220. Online ahead of print.ABSTRACTAs the number of vaccinated individuals has increased, there have been increasing reports of cutaneous hypersensitivity reactions. The main COVID-19 vaccines administered include messenger ribonucleic acid vaccines, non-replicating viral vector vaccines, inactivated whole-virus vaccines, and protein-based vaccines. These vaccines contain active components such as polyethylene glycol, polysorbate 80, aluminum, tromethamine, and disodium edetate dihydrate. Recent advances in understanding the coordination of inflammatory response...
Source: Clinical Immunology - April 20, 2024 Category: Allergy & Immunology Authors: Po-Chien Wu Wan-Chen Lin Chuang-Wei Wang Wen-Hung Chung Chun-Bing Chen Source Type: research
How do we change our approach to COVID with the changing face of disease?
Expert Rev Anti Infect Ther. 2024 Apr 20. doi: 10.1080/14787210.2024.2345881. Online ahead of print.ABSTRACTINTRODUCTION: The emergence of SARS-CoV-2 triggered a global health emergency, causing > 7 million deaths thus far. Limited early knowledge spurred swift research, treatment, and vaccine developments. Implementation of public health measures such as, lockdowns and social distancing, disrupted economies and strained healthcare. Viral mutations highlighted the need for flexible strategies and strong public health infrastructure, with global collaboration crucial for pandemic control.AREAS COVERED: (i) Revisiting dia...
Source: Expert Review of Anti-Infective Therapy - April 20, 2024 Category: Infectious Diseases Authors: Vasso Apostolopoulos Jack Feehan Vivek P Chavda Source Type: research
How do we change our approach to COVID with the changing face of disease?
Expert Rev Anti Infect Ther. 2024 Apr 26:1-9. doi: 10.1080/14787210.2024.2345881. Online ahead of print.ABSTRACTINTRODUCTION: The emergence of SARS-CoV-2 triggered a global health emergency, causing > 7 million deaths thus far. Limited early knowledge spurred swift research, treatment, and vaccine developments. Implementation of public health measures such as, lockdowns and social distancing, disrupted economies and strained healthcare. Viral mutations highlighted the need for flexible strategies and strong public health infrastructure, with global collaboration crucial for pandemic control.AREAS COVERED: (i) Revisiting...
Source: Expert Review of Anti-Infective Therapy - April 20, 2024 Category: Infectious Diseases Authors: Vasso Apostolopoulos Jack Feehan Vivek P Chavda Source Type: research
Influence of vaccination on critical COVID-19 patients with acute respiratory failure: a retrospective cohort study
ConclusionsVaccination status did not significantly influence mortality rates, the occurrence of ARDS, or the viral shedding duration in COVID-19 patients with acute respiratory failure. (Source: European Journal of Medical Research)
Source: European Journal of Medical Research - April 20, 2024 Category: Research Source Type: research
Incidence of SARS-CoV-2 Seropositivity in Pediatric Healthcare Workers Prior to Widespread Vaccination: A Five-month Longitudinal Cohort Study
CONCLUSION: Incidence of seropositivity was 8.2%. Although seropositivity was higher among ED staff during early stages of the pandemic, this difference declined over time, likely due to universal adoption of personal protective equipment (PPE).PMID:38641316 | DOI:10.1016/j.ijid.2024.107064 (Source: Pain Physician)
Source: Pain Physician - April 19, 2024 Category: Anesthesiology Authors: Mark Griffiths Dunia Hatabah Patrick Sullivan Grace Mantus Travis Sanchez Maria Zlotorzynska Stacy Heilman Andres Camacho-Gonzalez Deborah Leake Rawan Korman Mimi Le Mehul Suthara Jens Wrammert Miriam B Vos Claudia R Morris Source Type: research
Predictors of willingness to receive updated 2023-2024 COVID-19 booster vaccines among a convenience sample in Minnesota
CONCLUSIONS: Our study emphasizes the importance of perceived vaccine safety as a predictor of intention to accept COVID-19 vaccines and highlights the continued need to effectively communicate with the public about the safety of vaccines.PMID:38641495 | DOI:10.1016/j.vaccine.2024.04.053 (Source: Vaccine)
Source: Vaccine - April 19, 2024 Category: Allergy & Immunology Authors: I J Ricke A B Spaulding N N Rajtar E M Benton I G Anderson L Lundberg A Mussiel R H N Nguyen Source Type: research
