Clostridiodes difficile infection in inflammatory bowel disease: a clinical review
Expert Rev Anti Infect Ther. 2024 Apr 27. doi: 10.1080/14787210.2024.2347955. Online ahead of print.ABSTRACTINTRODUCTION: Strong clinical data demonstrate that inflammatory bowel disease (IBD) is an independent risk factor for Clostridiodes difficile infection (CDI) and suggest a globally increased prevalence and severity of C. difficile coinfection in IBD patients (CDI-IBD). In addition to elderly individuals, children are also at higher risk of CDI-IBD. Rapid diagnosis is essential since the clinical manifestations of active IBD and CDI-IBD are indistinguishable. Antibiotics have been well established in the treatment of...
Source: Expert Review of Anti-Infective Therapy - April 27, 2024 Category: Infectious Diseases Authors: Mengjun Tang Chunhua Wang Ying Xia Jian Tang Jiao Wang Liang Shen Source Type: research

How do we change our approach to COVID with the changing face of disease?
Expert Rev Anti Infect Ther. 2024 Apr 26:1-9. doi: 10.1080/14787210.2024.2345881. Online ahead of print.ABSTRACTINTRODUCTION: The emergence of SARS-CoV-2 triggered a global health emergency, causing > 7 million deaths thus far. Limited early knowledge spurred swift research, treatment, and vaccine developments. Implementation of public health measures such as, lockdowns and social distancing, disrupted economies and strained healthcare. Viral mutations highlighted the need for flexible strategies and strong public health infrastructure, with global collaboration crucial for pandemic control.AREAS COVERED: (i) Revisiting...
Source: Expert Review of Anti-Infective Therapy - April 20, 2024 Category: Infectious Diseases Authors: Vasso Apostolopoulos Jack Feehan Vivek P Chavda Source Type: research

Surveillance and prevention of healthcare-associated infections: best practices to prevent ventilator-associated events
Expert Rev Anti Infect Ther. 2024 Apr 22:1-16. doi: 10.1080/14787210.2024.2345877. Online ahead of print.ABSTRACTINTRODUCTION: Ventilator associated pneumonia (VAP) leads to an increase in morbidity, mortality, and healthcare costs. In addition to increased evidence from the latest European and American guidelines (published in 2017 and 2022, respectively), in the last two years, several important clinical experiences have added new prevention tools to be included to improve the management of VAP.AREAS COVERED: This paper is a narrative review of new evidence on VAP prevention. We divided VAP prevention measures into pharm...
Source: Expert Review of Anti-Infective Therapy - April 20, 2024 Category: Infectious Diseases Authors: Leonardo Lorente Joan Sabater-Riera Jordi Rello Source Type: research

How do we change our approach to COVID with the changing face of disease?
Expert Rev Anti Infect Ther. 2024 Apr 20. doi: 10.1080/14787210.2024.2345881. Online ahead of print.ABSTRACTINTRODUCTION: The emergence of SARS-CoV-2 triggered a global health emergency, causing > 7 million deaths thus far. Limited early knowledge spurred swift research, treatment, and vaccine developments. Implementation of public health measures such as, lockdowns and social distancing, disrupted economies and strained healthcare. Viral mutations highlighted the need for flexible strategies and strong public health infrastructure, with global collaboration crucial for pandemic control.AREAS COVERED: (i) Revisiting dia...
Source: Expert Review of Anti-Infective Therapy - April 20, 2024 Category: Infectious Diseases Authors: Vasso Apostolopoulos Jack Feehan Vivek P Chavda Source Type: research

Surveillance and prevention of healthcare-associated infections: best practices to prevent ventilator-associated events
Expert Rev Anti Infect Ther. 2024 Apr 22:1-16. doi: 10.1080/14787210.2024.2345877. Online ahead of print.ABSTRACTINTRODUCTION: Ventilator associated pneumonia (VAP) leads to an increase in morbidity, mortality, and healthcare costs. In addition to increased evidence from the latest European and American guidelines (published in 2017 and 2022, respectively), in the last two years, several important clinical experiences have added new prevention tools to be included to improve the management of VAP.AREAS COVERED: This paper is a narrative review of new evidence on VAP prevention. We divided VAP prevention measures into pharm...
Source: Expert Review of Anti-Infective Therapy - April 20, 2024 Category: Infectious Diseases Authors: Leonardo Lorente Joan Sabater-Riera Jordi Rello Source Type: research

How do we change our approach to COVID with the changing face of disease?
Expert Rev Anti Infect Ther. 2024 Apr 20. doi: 10.1080/14787210.2024.2345881. Online ahead of print.ABSTRACTINTRODUCTION: The emergence of SARS-CoV-2 triggered a global health emergency, causing > 7 million deaths thus far. Limited early knowledge spurred swift research, treatment, and vaccine developments. Implementation of public health measures such as, lockdowns and social distancing, disrupted economies and strained healthcare. Viral mutations highlighted the need for flexible strategies and strong public health infrastructure, with global collaboration crucial for pandemic control.AREAS COVERED: (i) Revisiting dia...
Source: Expert Review of Anti-Infective Therapy - April 20, 2024 Category: Infectious Diseases Authors: Vasso Apostolopoulos Jack Feehan Vivek P Chavda Source Type: research

Surveillance and prevention of healthcare-associated infections: best practices to prevent ventilator-associated events
Expert Rev Anti Infect Ther. 2024 Apr 22:1-16. doi: 10.1080/14787210.2024.2345877. Online ahead of print.ABSTRACTINTRODUCTION: Ventilator associated pneumonia (VAP) leads to an increase in morbidity, mortality, and healthcare costs. In addition to increased evidence from the latest European and American guidelines (published in 2017 and 2022, respectively), in the last two years, several important clinical experiences have added new prevention tools to be included to improve the management of VAP.AREAS COVERED: This paper is a narrative review of new evidence on VAP prevention. We divided VAP prevention measures into pharm...
Source: Expert Review of Anti-Infective Therapy - April 20, 2024 Category: Infectious Diseases Authors: Leonardo Lorente Joan Sabater-Riera Jordi Rello Source Type: research

Understanding the influence of the microbiome on childhood infections
Expert Rev Anti Infect Ther. 2024 Apr 12:1-17. doi: 10.1080/14787210.2024.2340664. Online ahead of print.ABSTRACTINTRODUCTION: The microbiome is known to have a substantial impact on human health and disease. However, the impacts of the microbiome on immune system development, susceptibility to infectious diseases, and vaccine-elicited immune responses are emerging areas of interest.AREAS COVERED: In this review, we provide an overview of development of the microbiome during childhood. We highlight available data suggesting that the microbiome is critical to maturation of the immune system and modifies susceptibility to a ...
Source: Expert Review of Anti-Infective Therapy - April 12, 2024 Category: Infectious Diseases Authors: Sarah M Heston Jillian H Hurst Matthew S Kelly Source Type: research

Response to: 'letter to the editor: "A multifaceted strategy is needed to limit the over-the-counter sale of antimicrobials "'
Expert Rev Anti Infect Ther. 2024 Apr 5:1-3. doi: 10.1080/14787210.2024.2337824. Online ahead of print.NO ABSTRACTPMID:38576383 | DOI:10.1080/14787210.2024.2337824 (Source: Expert Review of Anti-Infective Therapy)
Source: Expert Review of Anti-Infective Therapy - April 5, 2024 Category: Infectious Diseases Authors: Eric Kofi Ngyedu Joseph Elikem Efui Acolatse George Akafity Robert Incoom Audu Rauf R Andrew Seaton Jacqueline Sneddon Elaine Cameron Margaret Watson Marta Wanat Brian Godman Amanj Kurdi Source Type: research