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Is the world crippled by antimicrobial resistance, or simply lacking information?
Expert Rev Anti Infect Ther. 2024 Feb 21. doi: 10.1080/14787210.2024.2322429. Online ahead of print.NO ABSTRACTPMID:38381552 | DOI:10.1080/14787210.2024.2322429 (Source: Expert Review of Anti-Infective Therapy)
Source: Expert Review of Anti-Infective Therapy - February 21, 2024 Category: Infectious Diseases Authors: Ahmad Z Al Meslamani Source Type: research

An assessment of the index of rational drug prescribing for severe acute respiratory infections among hospitalised children in Northern Nigeria: a retrospective study
CONCLUSIONS: Drug prescribing for hospitalized children with SARI was suboptimal, especially with regard to polypharmacy, antibiotics, and injection use. Interventions to promote rational use of medicines including antimicrobial stewardship interventions are recommended.PMID:38334431 | DOI:10.1080/14787210.2024.2307913 (Source: Expert Review of Anti-Infective Therapy)
Source: Expert Review of Anti-Infective Therapy - February 9, 2024 Category: Infectious Diseases Authors: Aliyu Sulaiman Mohammad Alfa Isah Abubakar Usman Source Type: research

Safety and efficacy of Paxlovid in the treatment of adults with mild to moderate COVID-19 during the omicron epidemic: a multicentre study from China
CONCLUSION: Amid the Omicron outbreak, Paxlovid has proven to be a safe and effective treatment for reducing hospitalization durations for patients with mild to moderate COVID-19.PMID:38300126 | DOI:10.1080/14787210.2024.2309998 (Source: Expert Review of Anti-Infective Therapy)
Source: Expert Review of Anti-Infective Therapy - February 1, 2024 Category: Infectious Diseases Authors: Pulin Li Ling Huang Rui Han Min Tang Guanghe Fei Daxiong Zeng Ran Wang Source Type: research

Prevalence of antibiotic resistance in clinical isolates of < em > Mycobacterium kansasii < /em > : a systematic review and meta-analysis
Expert Rev Anti Infect Ther. 2024 Jan 31:1-11. doi: 10.1080/14787210.2024.2313051. Online ahead of print.ABSTRACTINTRODUCTION: The prevalence of diseases caused by non-tuberculous mycobacteria (NTM), including M. kansasii, is increasing, necessitating further information to guide prevention, control, and treatment strategies.AREAS COVERED: A comprehensive analysis of articles published until February 2023 was conducted on PubMed, Web of Science, and Scopus databases to investigate antibiotic resistance in M. kansasii species. Stata software version 17 was employed for all analyses.EXPERT OPINION: A total of 1647 articles w...
Source: Expert Review of Anti-Infective Therapy - January 31, 2024 Category: Infectious Diseases Authors: Negar Narimisa Forough Goodarzi Narjess Bostanghadiri Faramarz Masjedian Jazi Source Type: research

Biosimilars as antivirals: opportunities and challenges
Expert Rev Anti Infect Ther. 2024 Jan 30:1-3. doi: 10.1080/14787210.2024.2313064. Online ahead of print.NO ABSTRACTPMID:38288681 | DOI:10.1080/14787210.2024.2313064 (Source: Expert Review of Anti-Infective Therapy)
Source: Expert Review of Anti-Infective Therapy - January 30, 2024 Category: Infectious Diseases Authors: Anan S Jarab Shrouq R Abu Heshmeh Ahmad Z Al Meslamani Source Type: research

The clinical application of traditional Chinese medicine NRICM101 in hospitalized patients with COVID-19
CONCLUSION: NRICM101 did not reduce in-hospital mortality. However, it shortened the length of hospitalization and reduced mechanical ventilation days in initially severe cases. Further investigation is needed.PMID:38288986 | DOI:10.1080/14787210.2024.2313054 (Source: Expert Review of Anti-Infective Therapy)
Source: Expert Review of Anti-Infective Therapy - January 30, 2024 Category: Infectious Diseases Authors: Wen-Kuei Chang Chieh-Jen Wang Tung-Hu Tsai Fang-Ju Sun Chao-Hsien Chen Kuan-Chih Kuo Hsin-Pei Chung Yen-Hsiang Tang Yen-Ting Chen Kuo-Lun Wu Jou-Chun Wu Chang-Yi Lin Hai-Bo Zhang Source Type: research

Can adverse cardiac events of the COVID-19 vaccine exacerbate preexisting diseases?
Expert Rev Anti Infect Ther. 2024 Jan 29:1-7. doi: 10.1080/14787210.2024.2311837. Online ahead of print.ABSTRACTINTRODUCTION: SARS-CoV-2 infection and COVID-19 vaccination can both lead to serious cardiac conditions such as myocarditis, arrhythmia, acute myocardial infarction, and coagulopathy. Further studies are needed to better understand the risks and benefits of COVID-19 vaccination, and to determine the best course of action for individuals with preexisting heart conditions.AREAS COVERED: The current knowledge and challenges in understanding vaccine-associated heart issues concerning the COVID-19 pandemic are briefly...
Source: Expert Review of Anti-Infective Therapy - January 29, 2024 Category: Infectious Diseases Authors: Mohammed S Razzaque Source Type: research

Metallo-beta-lactamases: mechanisms, treatment challenges, and future prospects
We describe the mechanisms of action that differentiate MBLs from other beta-lactamases. We discuss the global epidemiology of MBL-producing organisms and their impact on patients' outcomes. By exposing the mechanisms of transmission of MBLs among bacterial populations, we emphasize the importance of infection prevention and control.EXPERT OPINION: MBLs are spreading globally and challenging the majority of available antibacterial agents. Genotypic tests play an important role in the identification of MBL production. Phenotypic tests are less specific but may be used in low-resource settings, where MBLs are more predominan...
Source: Expert Review of Anti-Infective Therapy - January 26, 2024 Category: Infectious Diseases Authors: Johnny Zakhour L'Emir Wassim El Ayoubi Souha S Kanj Source Type: research

Healthcare professionals' understanding and perception of drug-related issues linked to off-label pharmacological medications used for COVID-19
CONCLUSION: Most respondents had adequate knowledge. Older patients with comorbidities are at risk of adverse effects. Self-medication, polypharmacy, and multiple prescriptions can lead to misdiagnosis and complications. Electric prescriptions, team effort, and training programs can decrease these issues.PMID:38263904 | DOI:10.1080/14787210.2024.2310004 (Source: Expert Review of Anti-Infective Therapy)
Source: Expert Review of Anti-Infective Therapy - January 24, 2024 Category: Infectious Diseases Authors: Muhammad Zeeshan Munir Amer Hayat Khan Tahir Mehmood Khan Source Type: research

Ceftazidime-avibactam and aztreonam combination for Carbapenem-resistant Enterobacterales bloodstream infections with presumed < em > Metallo- β-lactamase < /em > production: a systematic review and meta-analysis
CONCLUSION: The meta-analysis from studies with a high risk of bias shows that AA is associated with lesser 30-day mortality when compared to polymyxins in patients with MBL-producing CRE BSI. Registration with PROSPERO- CRD42023433608.PMID:38258529 | DOI:10.1080/14787210.2024.2307912 (Source: Expert Review of Anti-Infective Therapy)
Source: Expert Review of Anti-Infective Therapy - January 23, 2024 Category: Infectious Diseases Authors: Nitin Gupta Carl Boodman Parikshit Prayag Abi Manesh Tirlangi Praveen Kumar Source Type: research

Drug recommendation for optimization on treatment outcome for MDR/RR-TB based on a multi-center, large scale, retrospective cohort study in China
CONCLUSIONS: The recommendation order for the treatment of MDR/RR-TB is Bdq, Lzd, and Cs. FQs were decreased in use intensity. Injection drugs, whether Amk or Cm, are not recommended.PMID:38251634 | DOI:10.1080/14787210.2024.2303032 (Source: Expert Review of Anti-Infective Therapy)
Source: Expert Review of Anti-Infective Therapy - January 22, 2024 Category: Infectious Diseases Authors: Lin Fan Ming Yang Yu-Tong Han Fei Ren Hua Wang Jin-Bao Ma Guo-Hui Zhu Yan-Jun Xiong Xin-Xin Fan Su-Xia Chen Hao-Yu Wu Wen-Wen Sun Shao-Jun Zhang Hui Ke Xiao-Hong Cheng Biao Xu Yu Chen Chang Chen Source Type: research