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Clinical management of Kaposi sarcoma herpesvirus-associated diseases: an update on disease manifestations and treatment strategies
Expert Rev Anti Infect Ther. 2023 Aug 15:1-13. doi: 10.1080/14787210.2023.2247161. Online ahead of print.ABSTRACTINTRODUCTION: Kaposi sarcoma herpes virus (KSHV) is associated with several diseases including Kaposi sarcoma, a form of multicentric Castleman's disease, primary effusion lymphoma, and an inflammatory cytokine syndrome. These KSHV-associated diseases (KAD) can present with heterogenous signs and symptoms that are often associated with cytokine dysregulation that may result in multiorgan dysfunction. The inability to promptly diagnose and treat these conditions can result in long-term complications and mortality...
Source: Expert Review of Anti-Infective Therapy - August 14, 2023 Category: Infectious Diseases Authors: Roshani Patel Kathryn Lurain Robert Yarchoan Ramya Ramaswami Source Type: research

Clinical management of Kaposi sarcoma herpesvirus-associated diseases: an update on disease manifestations and treatment strategies
Expert Rev Anti Infect Ther. 2023 Aug 14. doi: 10.1080/14787210.2023.2247161. Online ahead of print.ABSTRACTINTRODUCTION: Kaposi sarcoma herpes virus (KSHV) is associated with several diseases including Kaposi sarcoma, a form of multicentric Castleman's disease, primary effusion lymphoma, and an inflammatory cytokine syndrome. These KSHV-associated diseases (KAD) can present with heterogenous signs and symptoms that are often associated with cytokine dysregulation that may result in multiorgan dysfunction. Inability to promptly diagnose and treat these conditions can result in long term complications and mortality.AREAS CO...
Source: Expert Review of Anti-Infective Therapy - August 14, 2023 Category: Infectious Diseases Authors: Roshani Patel Kathryn Lurain Robert Yarchoan Ramya Ramaswami Source Type: research

Practices, Knowledge, and Attitudes of Nephrologists Towards Prescribing and Monitoring Vancomycin at Dialysis Centers
CONCLUSION: Findings showed that nephrologists have varying practices, moderate knowledge, and positive attitudes toward prescribing and monitoring vancomycin and highlight the need for interventions to overcome the perceived barriers.PMID:37551135 | DOI:10.1080/14787210.2023.2245566 (Source: Expert Review of Anti-Infective Therapy)
Source: Expert Review of Anti-Infective Therapy - August 8, 2023 Category: Infectious Diseases Authors: Sarah S Alghanem Manar Al-Otaibi Abdelmoneim Awad Source Type: research

Practices, knowledge, and attitudes of nephrologists towards prescribing and monitoring vancomycin at dialysis centers
CONCLUSION: Findings showed that nephrologists have varying practices, moderate knowledge, and positive attitudes toward prescribing and monitoring vancomycin and highlight the need for interventions to overcome the perceived barriers.PMID:37551135 | DOI:10.1080/14787210.2023.2245566 (Source: Expert Review of Anti-Infective Therapy)
Source: Expert Review of Anti-Infective Therapy - August 8, 2023 Category: Infectious Diseases Authors: Sarah S Alghanem Manar Al-Otaibi Abdelmoneim Awad Source Type: research

Nirmatrelvir and ritonavir combination: an antiviral therapy for COVID-19
Expert Rev Anti Infect Ther. 2023 Aug 1:1-13. doi: 10.1080/14787210.2023.2241638. Online ahead of print.ABSTRACTINTRODUCTION: The emergence of the Omicron SARS-CoV-2 variant of concern in late November 2021 presaged yet another stage of the COVID-19 pandemic. Paxlovid, a co-packaged dosage form of two antiviral drugs (nirmatrelvir and ritonavir) developed by Pfizer, received its first FDA Emergency Use Authorization (EUA) and conditional marketing by European Medical Agency in patients at high risk of developing severe COVID-19.AREAS COVERED: We reviewed the timeline of the drug nirmatrelvir from its discovery to authoriza...
Source: Expert Review of Anti-Infective Therapy - August 1, 2023 Category: Infectious Diseases Authors: Gangireddy Navitha Reddy Akanksha Jogvanshi Sana Naikwadi Rajesh Sonti Source Type: research