Efficacy and safety of the all-oral bedaquiline-containing regimen as treatment for pediatric multidrug/rifampicin-resistant tuberculosis: a multicenter, retrospective, cohort study
CONCLUSIONS: The all-oral BDQ-containing regimens may be effective and safe in the Chinese pediatric population.PMID:37982155 | DOI:10.1080/14787210.2023.2285917 (Source: Expert Review of Anti-Infective Therapy)
Source: Expert Review of Anti-Infective Therapy - November 20, 2023 Category: Infectious Diseases Authors: Wen-Wen Sun Ming Yang Xiao-Hong Chen Li-Chao Fan Hao-Yu Wu Shao-Jun Zhang Yu Chen Lin Fan Source Type: research

Health literacy, knowledge, household disposal, and misuse practices of antibiotics among UAE residents: a nationwide cross-sectional study
CONCLUSIONS: Higher levels of adequate health literacy were observed in those involved in the medical field and those with higher educational levels. The prevalence of self-medication with antibiotics among the UAE population was low. These findings highlight the importance of improving health literacy, promoting responsible antibiotic use, and encouraging proper disposal practices among the population.PMID:37978885 | DOI:10.1080/14787210.2023.2284878 (Source: Expert Review of Anti-Infective Therapy)
Source: Expert Review of Anti-Infective Therapy - November 18, 2023 Category: Infectious Diseases Authors: Zelal Kharaba Sayer Al-Azzam Shoroq M Altawalbeh Alin Alkwarit Noor Abdulkareem Salmeh Yassen Alfoteih Mohammad Araydah Reema Karasneh Mamoon A Aldeyab Source Type: research

Impact of a multidisciplinary antimicrobial stewardship program on antibiotic utilization and clinical outcomes at a tertiary hospital in Saudi Arabia: a quasi-experimental study
CONCLUSION: The implemented multidisciplinary ASP intervention was associated with a significant improvement in antibiotic utilization and patient clinical outcomes.PMID:37974376 | DOI:10.1080/14787210.2023.2285425 (Source: Expert Review of Anti-Infective Therapy)
Source: Expert Review of Anti-Infective Therapy - November 17, 2023 Category: Infectious Diseases Authors: Khadijah A Sarkhi Khalid Eljaaly Reham Kaki Rahaf Bahamdan Sultan A Alghamdi Mohammed O Baharith Abrar K Thabit Source Type: research

Selling antibiotics without prescriptions among community pharmacies and drug outlets: a simulated client study from Ghana
CONCLUSIONS: A very high prevalence/sub-optimal practice of selling antibiotics without prescriptions was found. This highlights the need to increase compliance with antibiotic dispensing legislation through evidence-based interventions including education of key stakeholders.PMID:37975725 | DOI:10.1080/14787210.2023.2283037 (Source: Expert Review of Anti-Infective Therapy)
Source: Expert Review of Anti-Infective Therapy - November 17, 2023 Category: Infectious Diseases Authors: Eric Kofi Ngyedu Joseph Acolatse George Akafity Robert Incoom Audu Rauf R Andrew Seaton Jacqueline Sneddon Elaine Cameron Margaret Watson Marta Wanat Brian Godman Amanj Kurdi Source Type: research

Impact of a multidisciplinary antimicrobial stewardship program on antibiotic utilization and clinical outcomes at a tertiary hospital in Saudi Arabia: a quasi-experimental study
CONCLUSION: The implemented multidisciplinary ASP intervention was associated with a significant improvement in antibiotic utilization and patient clinical outcomes.PMID:37974376 | DOI:10.1080/14787210.2023.2285425 (Source: Expert Review of Anti-Infective Therapy)
Source: Expert Review of Anti-Infective Therapy - November 17, 2023 Category: Infectious Diseases Authors: Khadijah A Sarkhi Khalid Eljaaly Reham Kaki Rahaf Bahamdan Sultan A Alghamdi Mohammed O Baharith Abrar K Thabit Source Type: research

Selling antibiotics without prescriptions among community pharmacies and drug outlets: a simulated client study from Ghana
CONCLUSIONS: A very high prevalence/sub-optimal practice of selling antibiotics without prescriptions was found. This highlights the need to increase compliance with antibiotic dispensing legislation through evidence-based interventions including education of key stakeholders.PMID:37975725 | DOI:10.1080/14787210.2023.2283037 (Source: Expert Review of Anti-Infective Therapy)
Source: Expert Review of Anti-Infective Therapy - November 17, 2023 Category: Infectious Diseases Authors: Eric Kofi Ngyedu Joseph Acolatse George Akafity Robert Incoom Audu Rauf R Andrew Seaton Jacqueline Sneddon Elaine Cameron Margaret Watson Marta Wanat Brian Godman Amanj Kurdi Source Type: research

The gut and lung microbiota in pulmonary tuberculosis: susceptibility, function, and new insights into treatment
Expert Rev Anti Infect Ther. 2023 Nov 16. doi: 10.1080/14787210.2023.2283036. Online ahead of print.ABSTRACTINTRODUCTION: Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis (Mtb) that poses a major threat to human health.AREAS COVERED: Herein, we aim to review the alteration of the microbiota in gut and respiratory during TB development, the potential function and mechanisms of microbiota in the pathogenesis of Mtb infection, and the impact of antibiotic treatment on the microbiota. In addition, we discuss the potential new paradigm for the use of microbiota-based treatments such as prob...
Source: Expert Review of Anti-Infective Therapy - November 16, 2023 Category: Infectious Diseases Authors: Qiqi Zhuo Xianyi Zhang Kehong Zhang Chan Chen Zhen Huang Yuzhong Xu Source Type: research

Clinical efficacy of nirmatrelvir plus ritonavir in patients with COVID-19 and preexisting cardiovascular diseases
CONCLUSIONS: Our findings indicate that NMV-r to treat COVID-19 could reduce all-cause hospitalization and death in patients with CVDs.PMID:37965890 | DOI:10.1080/14787210.2023.2284367 (Source: Expert Review of Anti-Infective Therapy)
Source: Expert Review of Anti-Infective Therapy - November 15, 2023 Category: Infectious Diseases Authors: Ting-Hui Liu Jheng-Yan Wu Po-Yu Huang Wan-Hsuan Hsu Min-Hsiang Chuang Ya-Wen Tsai Chih-Cheng Lai Chun-Yen Huang Source Type: research