The clinical outcomes and effectiveness of antiviral agents among underweight patients with COVID-19
CONCLUSION: Underweight status may be associated with ahigher risk of all-cause hospitalization and death in patients with COVID-19.Among underweight patients, antiviral agents demonstrated clinically beneficial effects.PMID:38178687 | DOI:10.1080/14787210.2024.2303017 (Source: Expert Review of Anti-Infective Therapy)
Source: Expert Review of Anti-Infective Therapy - January 5, 2024 Category: Infectious Diseases Authors: Jheng-Yan Wu Mei-Yuan Liu Mei-Chuan Lee Kuo-Chuan Hung Wan-Hsuan Hsu Ya-Wen Tsai Ting-Hui Liu Po-Yu Huang Min-Hsiang Chuang Shu-Ching Tseng Chih-Ying Lu Chih-Cheng Lai Source Type: research

Understanding < em > staphylococcus aureus < /em > internalization and induction of antimicrobial tolerance
Expert Rev Anti Infect Ther. 2024 Jan 5. doi: 10.1080/14787210.2024.2303018. Online ahead of print.ABSTRACTINTRODUCTION: Staphylococcus aureus, a human commensal, is also one of the most common and serious pathogens for humans. In recent years, its capacity to survive and replicate in phagocytic and non-phagocytic cells has been largely demonstrated. In these intracellular niches, bacteria are shielded from the immune response and antibiotics, turning host cells into long-term infectious reservoirs. Moreover, neutrophils carry intracellular bacteria in the bloodstream, leading to systemic spreading of the disease. Despite ...
Source: Expert Review of Anti-Infective Therapy - January 5, 2024 Category: Infectious Diseases Authors: Fr édéric Goormaghtigh Fran çoise Van Bambeke Source Type: research

Bacterial Co-infections, secondary Infections and antimicrobial use among hospitalized COVID-19 patients in the sixth wave in Pakistan: findings and implications
Conclusion: There continued to be excessive antibiotics use among hospitalized COVID-19 patients. Urgent measures are needed to address inappropriate prescribing including greater prescribing of Access antibiotics where pertinent.PMID:38146949 | DOI:10.1080/14787210.2023.2299387 (Source: Expert Review of Anti-Infective Therapy)
Source: Expert Review of Anti-Infective Therapy - December 26, 2023 Category: Infectious Diseases Authors: Zia Ul Mustafa Arfa Batool Hadia Ibrar Muhammad Salman Yusra Habib Khan Tauqeer Hussain Malhi Johanna C Meyer Brian Godman Catrin E Moore Source Type: research

Clinical utility of procalcitonin in implementation of procalcitonin-guided antibiotic stewardship in the South-East Asia and India: evidence and consensus-based recommendations
Expert Rev Anti Infect Ther. 2023 Dec 19:1-14. doi: 10.1080/14787210.2023.2296066. Online ahead of print.ABSTRACTINTRODUCTION: The South-East Asian (SEA) region and India are highly susceptible to antibiotic resistance, which is caused due to lack of antimicrobial stewardship (AMS) knowledge, uncontrolled use of antibiotics, and poor infection control. Nonadherence to national/local guidelines, developed to combat antimicrobial resistance, is a major concern. A virtual advisory board was conducted to understand the current AMS standards and challenges in its implementation in these regions.AREAS COVERED: Procalcitonin (PCT...
Source: Expert Review of Anti-Infective Therapy - December 19, 2023 Category: Infectious Diseases Authors: Andrea Lay-Hoon Kwa Brigitte Rina Aninda Sidharta Do Ngoc Son Kapil Zirpe Petrick Periyasamy Rongpong Plongla Subramanian Swaminathan Tonny Loho Vu Van Giap Anucha Apisarnthanarak Source Type: research