Phthalates exposure and uterine fibroid burden among women undergoing surgical treatment for fibroids: a preliminary study
To examine the association between phthalate exposure and two measures of uterine fibroid burden: diameter of largest fibroid and uterine volume. (Source: Fertility and Sterility)
Source: Fertility and Sterility - November 14, 2018 Category: Reproduction Medicine Authors: Ami R. Zota, Ruth J. Geller, Antonia M. Calafat, Cherie Q. Marfori, Andrea A. Baccarelli, Gaby N. Moawad Tags: Environment Source Type: research

Metabolic imaging with the use of  fluorescence lifetime imaging microscopy (FLIM) accurately detects mitochondrial dysfunction in mouse oocytes
To determine whether metabolic imaging with the use of fluorescence lifetime imaging microscopy (FLIM) identifies metabolic differences between normal oocytes and those with metabolic dysfunction. (Source: Fertility and Sterility)
Source: Fertility and Sterility - November 14, 2018 Category: Reproduction Medicine Authors: Tim Sanchez, Tianren Wang, Marta Venturas Pedro, Man Zhang, Ecem Esencan, Denny Sakkas, Dan Needleman, Emre Seli Tags: Reproductive science Source Type: research

Developmental potential of slow-developing embryos: day-5 morulae compared with day-5 cavitating morulae
To describe and compare the ongoing pregnancy rate between morulae and cavitating morulae (CAVM) transferred on day 5, to describe and compare the blastulation rate between day 5 morulae and CAVM, and to describe the pregnancy rate of these slow-developing blastocysts during a frozen embryo transfer (FET) cycle. (Source: Fertility and Sterility)
Source: Fertility and Sterility - November 12, 2018 Category: Reproduction Medicine Authors: Jigal Haas, Jim Meriano, Rawad Bassil, Eran Barzilay, Eran Zilberberg, Robert F. Casper Tags: Original article Source Type: research

Home sperm testing device versus laboratory sperm quality analyzer: comparison of motile sperm concentration
To test the ability of the smartphone-based YO Home Sperm Test to accurately and precisely measure motile sperm concentration (MSC) versus the SQA-Vision, an automated laboratory semen analyzer. (Source: Fertility and Sterility)
Source: Fertility and Sterility - November 10, 2018 Category: Reproduction Medicine Authors: Ashok Agarwal, Manesh Kumar Panner Selvam, Rakesh Sharma, Kruyanshi Master, Aditi Sharma, Sajal Gupta, Ralf Henkel Tags: Original article Source Type: research

Transfer of embryos with segmental mosaicism is associated with a significant reduction in live-birth rate
To evaluate the impact of segmental mosaicism on pregnancy outcomes from the transfer of embryos previously designated as euploid. (Source: Fertility and Sterility)
Source: Fertility and Sterility - November 10, 2018 Category: Reproduction Medicine Authors: Temeka Zore, Lindsay L. Kroener, Chunmin Wang, Lian Liu, Richard Buyalos, Gary Hubert, Mousa Shamonki Tags: Original article Source Type: research

Commentary: when embryos hit the brakes
If we have gleaned any one general principle from the time-lapse literature with regard to embryo selection, it is this: successful outcome from the transfer of a blastocyst depends somewhat upon it reaching that stage but even more so upon how and when it was reached. The simple visualization of an emerging fluid-filled space in a morula belies the underlying workings of a myriad of ordered molecular interactions. Without a doubt, blastulation is a complex process, with the resulting blastocyst representing the successful derivation of divergent cell lineages, a culmination of an ordered sequence of events that begins wit...
Source: Fertility and Sterility - November 10, 2018 Category: Reproduction Medicine Authors: Thomas B. Pool Tags: Reflections Source Type: research

What are patients doing with their mosaic embryos? Decision making after genetic counseling
To assess patient decisions regarding mosaic embryos and their impact on clinical outcomes. (Source: Fertility and Sterility)
Source: Fertility and Sterility - November 10, 2018 Category: Reproduction Medicine Authors: Andria G. Besser, David H. McCulloh, James A. Grifo Tags: Original article Source Type: research

Singleton fetal growth kinetics depend on the mode of conception
To study the impact of in  vitro fertilization, with or without intracytoplasmic sperm injection (IVF/ICSI), frozen-embryo transfer (FET), and intrauterine insemination (IUI) on fetal growth kinetics throughout pregnancy and to compare the different modes of conception. (Source: Fertility and Sterility)
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Authors: Perrine Ginod, C écile Choux, Julie Barberet, Thierry Rousseau, Céline Bruno, Bouchra Khallouk, Paul Sagot, Karine Astruc, Patricia Fauque Tags: Original article Source Type: research

A sonographic classification of adenomyosis: interobserver reproducibility in the evaluation of type and degree of the myometrial involvement
To study the interobserver reproducibility of our new ultrasonographic mapping system to define the type and extension of uterine adenomyosis. (Source: Fertility and Sterility)
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Authors: Lucia Lazzeri, Giulia Morosetti, Gabriele Centini, Giorgia Monti, Errico Zupi, Emilio Piccione, Caterina Exacoustos Tags: Original article Source Type: research

Dietary factors and serum antim üllerian hormone concentrations in late premenopausal women
To study the associations between dietary factors and circulating antim üllerian hormone (AMH) concentrations among late premenopausal women. (Source: Fertility and Sterility)
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Authors: Chelsea Anderson, Yong-Moon Mark Park, Frank Z. Stanczyk, Dale P. Sandler, Hazel B. Nichols Tags: Original article Source Type: research

International Committee for Monitoring Assisted Reproductive Technology: world report on assisted reproductive technology, 2011
To report the utilization, effectiveness, and safety of practices in assisted reproductive technology (ART) globally in 2011 and assess global trends over time. (Source: Fertility and Sterility)
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Authors: G. David Adamson, Jacques de Mouzon, Georgina M. Chambers, Fernando Zegers-Hochschild, Ragaa Mansour, Osamu Ishihara, Manish Banker, Silke Dyer Tags: Original article Source Type: research

Experimental pain tolerance is decreased and independent of clinical pain intensity in patients with endometriosis
To investigate alterations in tactile, pain thresholds and pain tolerance thresholds in patients with endometriosis using a multimodality approach. (Source: Fertility and Sterility)
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Authors: Mieke van Aken, Joukje Oosterman, Tineke van Rijn, Kelly Woudsma, Magdalena Ferdek, G é Ruigt, Tamas Kozicz, Didi Braat, Ard Peeters, Annemiek Nap Tags: Original article Source Type: research

Effects of medical comorbidity on male infertility and comorbidity treatment on spermatogenesis
To investigate the prevalence and effects of medical comorbidities on spermatogenesis and to determine whether the treatment of medical comorbidities effectively improves spermatogenesis. (Source: Fertility and Sterility)
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Authors: Koji Shiraishi, Hideyasu Matsuyama Tags: Seminal Contribution Source Type: research

Organophosphate flame-retardant metabolite concentrations and pregnancy loss among women conceiving with assisted reproductive technology
To evaluate whether urinary concentrations of organophosphate flame retardant (PFR) metabolites are associated with pregnancy loss among women conceiving with assisted reproductive technology (ART). (Source: Fertility and Sterility)
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Authors: Carmen Messerlian, Paige L. Williams, Lidia M ínguez-Alarcón, Courtney C. Carignan, Jennifer B. Ford, Craig M. Butt, John D. Meeker, Heather M. Stapleton, Irene Souter, Russ Hauser, EARTH Study Team Tags: Original article Source Type: research

Control of endometriosis-associated pain with etonogestrel-releasing contraceptive implant and 52-mg levonorgestrel-releasing intrauterine system: randomized clinical trial
To assess the efficacy of an etonogestrel (ENG)-releasing contraceptive implant or the 52-mg levonorgestrel-releasing intrauterine system (LNG-IUS) in the control of endometriosis-associated pelvic pain. (Source: Fertility and Sterility)
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Authors: Nelsilene Carvalho, Deborah Margatho, Kleber Cursino, Cristina L. Benetti-Pinto, Luis Bahamondes Tags: Original article Source Type: research

The role of immunotherapy in in  vitro fertilization and recurrent pregnancy loss: a systematic review and meta-analysis
To study the current evidence on the role of immunotherapy in IVF and in the management of recurrent pregnancy loss (RPL). (Source: Fertility and Sterility)
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Authors: Chiara Achilli, Montserrat Duran-Retamal, Wael Saab, Paul Serhal, Srividya Seshadri Tags: Original article Source Type: research

Stage-specific modulation of antim üllerian hormone promotes primate follicular development and oocyte maturation in the matrix-free three-dimensional culture
To study whether follicular growth and oocyte maturation can be improved by antim üllerian hormone (AMH) modulation at specific stages of follicular development. (Source: Fertility and Sterility)
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Authors: Jing Xu, Maralee S. Lawson, Shoukhrat M. Mitalipov, Byung S. Park, Fuhua Xu Tags: Original article Source Type: research

Supplementation of cryopreservation medium with TAT-Peroxiredoxin 2 fusion protein improves human sperm quality and function
To investigate the potential effects of TAT-PRDX2 protein supplementation to the cryopreservation medium on post-thaw sperm quality and function. (Source: Fertility and Sterility)
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Authors: Juan Liu, Wenting Wang, Xin Liu, Xuebo Wang, Jiahui Wang, Yanwei Wang, Ning Li, Xiong Wang Tags: Original article Source Type: research

Relevance of International Committee for Monitoring Assisted Reproductive Technology (ICMART) Registry report 2011
The International Committee for Monitoring Assisted Reproductive Technology (ICMART) promotes and develops national and regional ART registries to monitor safety and efficacy in ART treatment worldwide. This is the 16th ICMART World Report and the most comprehensive global ART statistical report using aggregate country data (1). Despite the remarkable task of coordinating, executing, and completing such an endeavor, there are obvious limitations of the current registry report, as pointed out by the authors. (Source: Fertility and Sterility)
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Authors: David B. Seifer Tags: Reflections Source Type: research

Patient experience in a randomized trial of a weekly progesterone vaginal ring versus a daily progesterone gel for luteal support after in  vitro fertilization
To assess patient experience and convenience of using progesterone vaginal ring (VR) versus vaginal gel for women requiring luteal phase support during in  vitro fertilization (IVF). (Source: Fertility and Sterility)
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Authors: Elizabeth S. Ginsburg, Teru Jellerette-Nolan, Gaurang Daftary, Yunling Du, Kaylen M. Silverberg Tags: Original article Source Type: research

National survey of the Society for Assisted Reproductive Technology membership regarding insurance coverage for assisted reproductive technologies
To assess the attitudes of Society for Assisted Reproductive Technology (SART) members regarding expanding insurance coverage for patients seeking assisted reproductive technologies (ART) and identify some of the factors that may influence such attitudes. (Source: Fertility and Sterility)
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Authors: David B. Seifer, Ethan Wantman, Amy E. Sparks, Barbara Luke, Kevin J. Doody, James P. Toner, Bradley J. van Voorhis, Paul C. Lin, Richard H. Reindollar Tags: Original article Source Type: research

Influence of temperature, serum, and gonadotropin supplementation in short- and long-term organotypic culture of human immature testicular tissue
To study how temperature, serum, and gonadotropin supplementation affect the organotypic culture of human immature testicular tissue (ITT) in  vitro. (Source: Fertility and Sterility)
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Authors: Jose V. Medrano, Teresa Vilanova-P érez, Victoria Fornés-Ferrer, Ana Navarro-Gomezlechon, María L. Martínez-Triguero, Sofía García, Javier Gómez-Chacón, Ivan Povo, Antonio Pellicer, María M. Andrés, Edurne Novella-Maestre Tags: Original article Source Type: research

Changes in serum antim üllerian hormone levels in patients 6 and 12 months after endometrioma stripping surgery
To investigate the impact of laparoscopic endometrioma cystectomy on the ovarian reserve and to identify the most important factors that predict the ovarian reserve in patients with endometriomas. (Source: Fertility and Sterility)
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Authors: Vera Miodrag Kova čević, Luka Momir Anđelić, Ana Mitrović Jovanović Tags: Original article Source Type: research

Elusive adenomyosis: a plea for an international classification system to allow artificial intelligence approaches to reset our clinical management
Adenomyosis may be more elusive than ever! In the wake of technological progress, the definition and the clinical burden associated with adenomyosis have dramatically changed over the last 20  years. We went from a disease with a diagnosis based on hysterectomy specimens from patients in their 40s who were undergoing surgery for severe uterine bleeding, to a disease diagnosed via transvaginal ultrasound and/or magnetic resonance imaging (MRI) (1–4). As these technologies continue to i mprove with each passing year, 5 years from now our clinical decisions will likely be based on different criteria. (Source: ...
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Authors: Michel Canis, Anne Sophie Gremeau, Nicolas Bourdel Tags: Reflections Source Type: research

Conflicting messages on diet and fertility: food for thought
“How can I change my diet to improve my fertility?” This is one of the most frequently asked fertility-related questions to both providers and Google over the last several years, indicating that women of reproductive age have a vested interest in the subject matter. The evaluation of diet and fe rtility is a growing area of epidemiologic research, and in recent years much work has focused on how diet may influence the rate of ovarian aging, a critical component of female fertility. The need for identifying modifiable lifestyle factors related to ovarian aging is becoming increasingly releva nt, as more women ch...
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Authors: Alexandra C. Purdue-Smithe, Sunni L. Mumford Tags: Reflections Source Type: research

Simplifying luteal phase support in stimulated assisted reproduction cycles
The luteal phase is a very popular yet complex and poorly understood topic in the field of in  vitro fertilization (IVF). After ovulation, the formation of the corpus luteum occurs under the influence of luteinizing hormone (LH). Studies in humans and primates have demonstrated that the corpus luteum requires a consistent LH stimulus to perform its physiologic function (1). In 1949, Georgea nna Jones first described luteal phase deficiency as the premature onset of menses resulting from deficient progesterone production, correctable by exogenous progesterone administration. (Source: Fertility and Sterility)
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Authors: Human M. Fatemi Tags: Reflections Source Type: research

Medical treatment of comorbidities among infertile men: a step toward improving semen quality and general health status of infertile men?
From a historical perspective, the main clinical and research focuses have been on the long-term health outcomes of infertile women, including the effects of ovarian stimulation on the risk of mortality and cancer. However, in recent years, it has become more evident that a man's reproductive and somatic health also are closely related. (Source: Fertility and Sterility)
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Authors: Clara Helene Glazer Tags: Reflections Source Type: research

Autotransplantation of fragmented ovarian cortical tissue: a laparoscopic demonstration
To describe and demonstrate a simple and secure procedure for laparoscopic autotransplantation of fragmented ovarian cortical tissue in women with diminished ovarian reserve as part of in  vitro activation (IVA) of ovarian follicles. (Source: Fertility and Sterility)
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Authors: Stine Aagaard Lunding, Susanne Elisabeth Pors, Stine Gry Kristensen, Claus Yding Andersen, Janni Vikkels ø Jeppesen, Kirsten Tryde Macklon, Anders Nyboe Andersen, Anette Tønnes Pedersen Tags: Original article Source Type: research

Planned oocyte cryopreservation for women seeking to preserve future reproductive potential: an Ethics Committee opinion
Planned oocyte cryopreservation ( “planned OC”) is an emerging but ethically permissible procedure that may help women avoid future infertility. Because planned OC is new and evolving, it is essential that women who are considering using it be informed about the uncertainties regarding its efficacy and long-term effects. (Source: Fertility and Sterility)
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Authors: Ethics Committee of the American Society for Reproductive Medicine Tags: ASRM pages Source Type: research

Against seminal principles: ethics, hubris, and lessons to learn from illicit inseminations
So I never conceptualized this kind of deception and betrayal. I expected the doctors to be truthful and honest … If he had told me that he didn't have enough donors and he had said, “Hey, I have more women on the list for insemination, I don't have enough donors,” … I would not like hearing that, but I can handle it… Had he told me it was going to be him using his own semen I would have been absolu tely creeped out.—Judith, research interview (Source: Fertility and Sterility)
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Authors: Jody Madeira, Steven R. Lindheim, Mark V. Sauer Tags: Inklings Source Type: research

Consideration of the gestational carrier: an Ethics Committee opinion
Intended parents engage with gestational carriers in an attempt to achieve their personal reproductive goals. All gestational carriers have a right to be fully informed of the risks as well as the contractual and legal aspects of the gestational-carrier process. Gestational carriers have autonomy in making their own decisions regarding medical care and should be free from undue influences by the stakeholders involved. They should have free access to and receive psychological evaluation and counseling before, during, and after participating. (Source: Fertility and Sterility)
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Authors: Ethics Committee of the American Society for Reproductive Medicine Tags: ASRM pages Source Type: research

Misconduct in third-party assisted reproduction: an Ethics Committee opinion
Earn online CME credit related to this document at www.asrm.org/elearn (Source: Fertility and Sterility)
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Authors: Ethics Committee of the American Society for Reproductive Medicine Tags: ASRM pages Source Type: research

Facts often fail to overcome  preconceived notions
“Study the past if you would define the future.”— Confucius (Source: Fertility and Sterility)
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Authors: Olivia Carpinello, Alan DeCherney Tags: Fertility and sterility: 50 years ago today Source Type: research

In  vitro culture of ovarian preantral follicles: a promising alternative for preserving fertility in cancer patients
The exponential increase in the number of ovarian tissue cryopreservation (OTC) procedures in Europe in recent years, becoming similar to the number of oocyte cryopreservations for cancer patients (1), is mainly due to the successful results after transplantation of cryopreserved ovarian tissue. Indeed, this strategy has led to restoration of ovarian function of ∼ 95% of the patients and more than 130 live births (1). As promising as these outcomes are, it is also important to bear in mind that the ischemia-reperfusion period in the first days after avascular transplantation leads to ovarian tissue damage and significa...
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Authors: Christiani A. Amorim Tags: Reflections Source Type: research

Is in  vitro organotypic culture the key to spermatogenesis of human immature testicular tissue?
Pediatric cancers, though uncommon, are on the rise. As of 2014, there were almost 210,000 male survivors of childhood cancers that were diagnosed from ages 0 to 19  years in the United States. With improved therapies and discovered cures, this number will continue to rise as these patients continue to survive into adulthood (1). Unfortunately, many of these therapies have gonadotoxic effects and challenge these men's ability to father children. Therefore, it is imperative to address fertility preservation in this patient population before inducing these deleterious effects. (Source: Fertility and Sterility)
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Authors: Gabriella J. Avellino, Kathleen Hwang Tags: Reflections Source Type: research

Universal assisted reproductive technology coverage: a worthy cause that promotes safety
I remember, when I was a young doctor completing my fellowship, my uncle always asking me if I had saved a life. My response was always the same: “If I have to save a life, as a reproductive endocrinologist, it really is a bad day.” It is too bad that lawmakers and insurance companies have that same attitude; practicing medicine that cures diseases and saves lives is worthwhile, but infertility, which is not about saving lives, is conside red to be a “luxury” not worthy of universal coverage. The study by Seifer et al. (Source: Fertility and Sterility)
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Authors: Steven D. Spandorfer Tags: Reflections Source Type: research

Revisiting the early days of oocyte and embryo donation: relevance to contemporary clinical practice
Oocyte and embryo donation have evolved significantly since they were first introduced to treat human infertility nearly four decades ago. Social, ethical, and regulatory challenges to oocyte and embryo donation have generated controversy and invited public scrutiny. However, oocyte and embryo donation continued to provide physicians the opportunity to treat the “untreatable.” Undoubtedly, clinical practices related to oocyte and embryo donation have greatly changed over the years. Yet, they have endured as viable choices of treatment for many patients and their physicians, remained popular owing to their versa...
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Authors: Mark V. Sauer Tags: Views and reviews Source Type: research

Oocyte donation: lessons from the past, directions for the future
Oocyte donation has its origins in the clandestine use of donated sperm more than 140  years ago. Since first described in 1983, oocyte donation has resulted in more than 50,000 births in the United States alone and today now accounts for more than 10% of all IVF cycles performed yearly in the United States. The use of donated oocytes has changed the human reproductive landscape, ch allenging the traditional norms of conception and parenthood. Oocyte donation has also provided a unique scientific model that separates the egg from the uterus, allowing the independent study of each in normal physiologic and pathological...
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Authors: Steven R. Lindheim, Susan C. Klock Tags: Views and reviews Source Type: research

Innovations in assisted reproductive technologies: impact on contemporary donor egg practice and future advances
Innovations in assisted reproductive technologies (ART) have driven progress in the donor egg field since the birth of the first baby derived from a donor egg in 1983. Over time, donor oocytes have become an increasingly used option for patients unable to conceive with autologous oocytes. In donor egg, the unique separation of the oocyte source and recipient uterus has created a model that has propelled advances in ART. Progressive ART innovations that have optimized the oocyte donor and resulting embryo include the following: evaluation of ovarian reserve, controlled ovarian hyperstimulation regimens that reduce the risk ...
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Authors: Mindy S. Christianson, Jos é Bellver Tags: Views and reviews Source Type: research

Oocyte donation: insights gleaned and future challenges
With the first successful report of an IVF pregnancy achieved via donor oocytes in 1984, the applications of assisted reproductive technology (ART) were further expanded to include women unable to conceive with their own oocytes. Today, oocyte donation makes up an increasingly large percentage of all ART cycles worldwide. Oocyte donation presents several unique challenges to clinicians as two separate interests, those of the donor and those of the recipient, must be represented. These challenges include successful preparation of the endometrium in donor oocyte recipients, the synchronization of donor/recipient cycles, and ...
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Authors: Alexis P. Melnick, Zev Rosenwaks Tags: Views and reviews Source Type: research

Editorial Board
(Source: Fertility and Sterility)
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Source Type: research

Table of Contents
(Source: Fertility and Sterility)
Source: Fertility and Sterility - November 1, 2018 Category: Reproduction Medicine Source Type: research

Primary hepatic pregnancy: report of  a case treated with laparoscopic approach and review of the literature
To report a case of primary hepatic pregnancy complicated by acute hemoperitoneum that was treated with a laparoscopic approach. (Source: Fertility and Sterility)
Source: Fertility and Sterility - October 1, 2018 Category: Reproduction Medicine Authors: Simone Garzon, Ricciarda Raffaelli, Umberto Montin, Fabio Ghezzi Tags: Original article Source Type: research

Diagnostic efficacy of blastocoel fluid and spent media as sources of DNA for preimplantation genetic testing in standard clinical conditions
To determine whether blastocoel fluid (BF) or spent blastocyst medium (SBM) is a suitable template for genotype and/or karyotype assessment of in  vitro fertilization–generated embryos. (Source: Fertility and Sterility)
Source: Fertility and Sterility - October 1, 2018 Category: Reproduction Medicine Authors: Antonio Capalbo, Valeria Romanelli, Cristina Patassini, Maurizio Poli, Laura Girardi, Adriano Giancani, Marta Stoppa, Danilo Cimadomo, Filippo Maria Ubaldi, Laura Rienzi Tags: Original article Source Type: research

Impact of male partner characteristics and semen parameters on in  vitro fertilization and obstetric outcomes in a frozen oocyte donor model
To examine the degree to which paternal variables of age, body mass index (BMI), and sperm parameters affect vitrified donor oocyte IVF outcomes. Previous studies examining the impact of male partner characteristics on in-vitro fertilization (IVF) have found conflicting results. Concerns are rising over the potential effects of paternal factors, such as age and obesity, on pregnancy and child health. Frozen donor oocyte IVF offers an ideal model to study these effects. (Source: Fertility and Sterility)
Source: Fertility and Sterility - October 1, 2018 Category: Reproduction Medicine Authors: Sarah M. Capelouto, Zsolt Peter Nagy, Daniel B. Shapiro, Sydney R. Archer, Deandrea P. Ellis, Alicia K. Smith, Jessica B. Spencer, Heather S. Hipp Tags: Original article Source Type: research

External validation of a prediction model to select the best day-three embryo for transfer in in  vitro fertilization or intracytoplasmatic sperm injection procedures
To evaluate the multivariate embryo selection model by van Loendersloot et  al. (2014) (VL) in a different geographical context. (Source: Fertility and Sterility)
Source: Fertility and Sterility - October 1, 2018 Category: Reproduction Medicine Authors: Celine Blank, Imke T. Duijf, Els Slappendel, Massimo Mischi, Saskia Houterman, Jacques. W.M. Maas, Petra de Sutter, Benedictus C. Schoot Tags: Original article Source Type: research

Relationship between umbilical cord sex hormone binding globulin, sex steroids, and age at menarche: a prospective cohort study
To study the role of the prenatal environment in regulating reproductive development by measuring the prospective association between umbilical cord concentrations of sex hormone binding globulin (SHBG; principal regulator of sex steroid activity), bioavailable sex steroids, and age at menarche. (Source: Fertility and Sterility)
Source: Fertility and Sterility - October 1, 2018 Category: Reproduction Medicine Authors: Martha Hickey, Lauren P. Lawson, Jennifer L. Marino, Jeffrey A. Keelan, Roger Hart Tags: Original article Source Type: research

Development of a clinical prediction model for diagnosing adenomyosis
To develop a multivariate prediction model for diagnosing adenomyosis using predictors available through transvaginal ultrasonography and clinical examinations. (Source: Fertility and Sterility)
Source: Fertility and Sterility - October 1, 2018 Category: Reproduction Medicine Authors: Tina Tellum, Staale Nygaard, Else K. Skovholt, Erik Qvigstad, Marit Lieng Tags: Original article Source Type: research

Parental subfertility and hypospadias and cryptorchidism in boys: results from two Danish birth cohorts
To study if parental subfertility is related to the occurrence of the male genital anomalies, cryptorchidism and hypospadias. (Source: Fertility and Sterility)
Source: Fertility and Sterility - October 1, 2018 Category: Reproduction Medicine Authors: Linn H åkonsen Arendt, Morten Søndergaard Lindhard, Camilla Kjersgaard, Tine Brink Henriksen, Jørn Olsen, Cecilia Høst Ramlau-Hansen Tags: Seminal contribution Source Type: research

Oligo-anovulation is not a rarer feature in women with documented endometriosis
To study the prevalence of oligo-anovulation in women suffering from endometriosis compared to that of women without endometriosis. (Source: Fertility and Sterility)
Source: Fertility and Sterility - October 1, 2018 Category: Reproduction Medicine Authors: Pietro Santulli, Chloe Tran, Vanessa Gayet, Mathilde Bourdon, Chloe Maignien, Louis Marcellin, Khaled Pocate-Cheriet, Charles Chapron, Dominique de Ziegler Tags: Original article Source Type: research