Association Between Intrapartum Nitrous Oxide for Labor Analgesia and Short-Term Neonatal Outcomes
CONCLUSION: In this single-center retrospective cohort of low-risk patients, intrapartum inhaled nitrous oxide, compared with the reception of no analgesia, was associated with a decreased risk for NICU admission but with an increased risk for hyperbilirubinemia; other outcomes did not differ. These findings may be used to counsel patients when considering nitrous oxide for labor analgesia.PMID:38484306 | DOI:10.1097/AOG.0000000000005554 (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - March 14, 2024 Category: OBGYN Authors: Anabel Starosta Lisbet Lundsberg Jennifer Culhane Caitlin Partridge Olga Grechukhina Moeun Son Source Type: research

A Contemporary View of Menopausal Hormone Therapy
Obstet Gynecol. 2024 Mar 14. doi: 10.1097/AOG.0000000000005553. Online ahead of print.ABSTRACTEnthusiasm for the use of hormones to ameliorate symptoms of perimenopause and menopause has waxed and waned over the years. Both treatment for symptoms and training of women's health care practitioners in the management of menopause have sharply declined since publication of the Women's Health Initiative initial results in 2002. Findings from that trial, which treated a population of older, asymptomatic patients, have been extrapolated over the past 21 years to all estrogen products, all menopausal women, and all delivery mechani...
Source: Obstetrics and Gynecology - March 14, 2024 Category: OBGYN Authors: Barbara Levy James A Simon Source Type: research

Child Protection System Removal and Short-Interval Births Among Individuals With Prenatal Substance Use
Obstet Gynecol. 2024 Mar 14. doi: 10.1097/AOG.0000000000005552. Online ahead of print.ABSTRACTChild protection systems often intervene after substance-exposed births but are not designed to address the postpartum needs of the delivering parent. In this retrospective cohort study, we aimed to estimate the association between early child protection system removal and high-risk subsequent birth trajectories among a cohort of mothers with substance-exposed births in California. Of 6,893 births in 2015 with documented prenatal drug and alcohol exposure, 20.4% of mothers experienced child protection system removal within 30 days...
Source: Obstetrics and Gynecology - March 14, 2024 Category: OBGYN Authors: Julia Reddy Davida Schiff Mishka Terplan Hendree Jones Emily Putnam-Hornstein Source Type: research

Association Between Intrapartum Nitrous Oxide for Labor Analgesia and Short-Term Neonatal Outcomes
CONCLUSION: In this single-center retrospective cohort of low-risk patients, intrapartum inhaled nitrous oxide, compared with the reception of no analgesia, was associated with a decreased risk for NICU admission but with an increased risk for hyperbilirubinemia; other outcomes did not differ. These findings may be used to counsel patients when considering nitrous oxide for labor analgesia.PMID:38484306 | DOI:10.1097/AOG.0000000000005554 (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - March 14, 2024 Category: OBGYN Authors: Anabel Starosta Lisbet Lundsberg Jennifer Culhane Caitlin Partridge Olga Grechukhina Moeun Son Source Type: research

A Contemporary View of Menopausal Hormone Therapy
Obstet Gynecol. 2024 Mar 14. doi: 10.1097/AOG.0000000000005553. Online ahead of print.ABSTRACTEnthusiasm for the use of hormones to ameliorate symptoms of perimenopause and menopause has waxed and waned over the years. Both treatment for symptoms and training of women's health care practitioners in the management of menopause have sharply declined since publication of the Women's Health Initiative initial results in 2002. Findings from that trial, which treated a population of older, asymptomatic patients, have been extrapolated over the past 21 years to all estrogen products, all menopausal women, and all delivery mechani...
Source: Obstetrics and Gynecology - March 14, 2024 Category: OBGYN Authors: Barbara Levy James A Simon Source Type: research

Child Protection System Removal and Short-Interval Births Among Individuals With Prenatal Substance Use
Obstet Gynecol. 2024 Mar 14. doi: 10.1097/AOG.0000000000005552. Online ahead of print.ABSTRACTChild protection systems often intervene after substance-exposed births but are not designed to address the postpartum needs of the delivering parent. In this retrospective cohort study, we aimed to estimate the association between early child protection system removal and high-risk subsequent birth trajectories among a cohort of mothers with substance-exposed births in California. Of 6,893 births in 2015 with documented prenatal drug and alcohol exposure, 20.4% of mothers experienced child protection system removal within 30 days...
Source: Obstetrics and Gynecology - March 14, 2024 Category: OBGYN Authors: Julia Reddy Davida Schiff Mishka Terplan Hendree Jones Emily Putnam-Hornstein Source Type: research

Association Between Intrapartum Nitrous Oxide for Labor Analgesia and Short-Term Neonatal Outcomes
CONCLUSION: In this single-center retrospective cohort of low-risk patients, intrapartum inhaled nitrous oxide, compared with the reception of no analgesia, was associated with a decreased risk for NICU admission but with an increased risk for hyperbilirubinemia; other outcomes did not differ. These findings may be used to counsel patients when considering nitrous oxide for labor analgesia.PMID:38484306 | DOI:10.1097/AOG.0000000000005554 (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - March 14, 2024 Category: OBGYN Authors: Anabel Starosta Lisbet Lundsberg Jennifer Culhane Caitlin Partridge Olga Grechukhina Moeun Son Source Type: research

A Contemporary View of Menopausal Hormone Therapy
Obstet Gynecol. 2024 Mar 14. doi: 10.1097/AOG.0000000000005553. Online ahead of print.ABSTRACTEnthusiasm for the use of hormones to ameliorate symptoms of perimenopause and menopause has waxed and waned over the years. Both treatment for symptoms and training of women's health care practitioners in the management of menopause have sharply declined since publication of the Women's Health Initiative initial results in 2002. Findings from that trial, which treated a population of older, asymptomatic patients, have been extrapolated over the past 21 years to all estrogen products, all menopausal women, and all delivery mechani...
Source: Obstetrics and Gynecology - March 14, 2024 Category: OBGYN Authors: Barbara Levy James A Simon Source Type: research

Child Protection System Removal and Short-Interval Births Among Individuals With Prenatal Substance Use
Obstet Gynecol. 2024 Mar 14. doi: 10.1097/AOG.0000000000005552. Online ahead of print.ABSTRACTChild protection systems often intervene after substance-exposed births but are not designed to address the postpartum needs of the delivering parent. In this retrospective cohort study, we aimed to estimate the association between early child protection system removal and high-risk subsequent birth trajectories among a cohort of mothers with substance-exposed births in California. Of 6,893 births in 2015 with documented prenatal drug and alcohol exposure, 20.4% of mothers experienced child protection system removal within 30 days...
Source: Obstetrics and Gynecology - March 14, 2024 Category: OBGYN Authors: Julia Reddy Davida Schiff Mishka Terplan Hendree Jones Emily Putnam-Hornstein Source Type: research

An Update on Prenatal Diethylstilbestrol Exposure and High-Grade Squamous Intraepithelial Lesions of the Lower Genital Tract
We report the results of a prospective follow-up study of prenatal diethylstilbestrol exposure and lower genital tract high-grade (grade 2 or higher) squamous intraepithelial lesions (HSIL). The age-adjusted risk of HSIL among diethylstilbestrol-exposed women (n=4,062) was higher than among the diethylstilbestrol unexposed (n=1,837) through age 44 years (hazard ratio 2.03, 95% CI, 1.31-3.14) but not age 45 years or older. Elevated HSIL risk remained higher in diethylstilbestrol-exposed women, after accounting for frequency of cervical cancer screening. Compared with unexposed women, HSIL risk was higher among women with ea...
Source: Obstetrics and Gynecology - February 29, 2024 Category: OBGYN Authors: Rebecca Troisi Kimberly Bertrand Elizabeth E Hatch William C Strohsnitter Kjersti Aagaard Stanley J Robboy Gretchen Gierach Linda Titus Source Type: research

Pregnancy Outcomes After Laparoscopic Radiofrequency Ablation of Uterine Leiomyomas Compared With Myomectomy
CONCLUSION: Full-term pregnancy and vaginal delivery are achievable after radiofrequency ablation of leiomyomas. However, in this interim analysis, the miscarriage rate in both radiofrequency ablation and myomectomy groups was higher than expected for women in this age group. Long-term data collection in the ongoing ULTRA study aims to further understand pregnancy outcomes after radiofrequency ablation compared with myomectomy.CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov, NCT0210094.PMID:38422502 | DOI:10.1097/AOG.0000000000005548 (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - February 29, 2024 Category: OBGYN Authors: Antoinette Allen Michael Schembri Ram Parvataneni L Elaine Waetjen Shira Varon Naghmeh Salamat-Saberi Shawn Tassone Nicole Williams Kimberly A Kho Vanessa L Jacoby Source Type: research

Association of Adverse Childhood Experiences and Resilience With Depression and Anxiety During Pregnancy
Obstet Gynecol. 2024 Feb 29. doi: 10.1097/AOG.0000000000005545. Online ahead of print.ABSTRACTThis was a retrospective cohort study of pregnant individuals in the Kaiser Permanente Northern California system who were screened for adverse childhood experiences and resilience as part of standard prenatal care at about 16 weeks of gestation. Overall, 14,625 pregnancies were included; 17.0% had newly identified depression; 9.8% had newly identified depression symptoms; and 8.9% had newly identified anxiety during the pregnancy with no known preexisting diagnosis. We found that adverse childhood experiences and low resilience w...
Source: Obstetrics and Gynecology - February 29, 2024 Category: OBGYN Authors: Carey R Watson Abigail Eaton Cynthia I Campbell Stacey E Alexeeff Lyndsay A Avalos Kathryn K Ridout Kelly C Young-Wolff Source Type: research

Universal Fetal Echocardiography for Pregestational Diabetes Mellitus: A Cost-Effectiveness Analysis
CONCLUSION: For pregnant patients with first-trimester Hb A1c levels lower than 6.5%, universal fetal echocardiogram was not cost effective, whereas, for those with first-trimester Hb A1c levels higher than 9.0%, universal fetal echocardiogram was cost effective. For those with intermediate Hb A1c levels, universal fetal echocardiogram was cost effective in about 50% of cases; therefore, clinical judgment based on individual patient values, willingness to pay to detect congenital heart disease, and resource availability needs to be considered.PMID:38422504 | DOI:10.1097/AOG.0000000000005538 (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - February 29, 2024 Category: OBGYN Authors: Leah M Savitsky Caitlin Hamilton Mary Sterrett Kelsey Olerich Kimberly Ma Catherine M Albright Source Type: research

Applying Tension to the Transcervical Foley Balloon and Delivery Times in Term Nulliparous Women Undergoing Induction of Labor: A Randomized Controlled Trial
CONCLUSION: Applying tension to a transcervical Foley balloon in term nulliparous women undergoing labor induction did not significantly reduce delivery time or improve secondary outcomes.CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov, NCT05404776.PMID:38422505 | DOI:10.1097/AOG.0000000000005546 (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - February 29, 2024 Category: OBGYN Authors: Meagan Benson Lena Younes Alisha Watson George R Saade Antonio F Saad Source Type: research

An Update on Prenatal Diethylstilbestrol Exposure and High-Grade Squamous Intraepithelial Lesions of the Lower Genital Tract
We report the results of a prospective follow-up study of prenatal diethylstilbestrol exposure and lower genital tract high-grade (grade 2 or higher) squamous intraepithelial lesions (HSIL). The age-adjusted risk of HSIL among diethylstilbestrol-exposed women (n=4,062) was higher than among the diethylstilbestrol unexposed (n=1,837) through age 44 years (hazard ratio 2.03, 95% CI, 1.31-3.14) but not age 45 years or older. Elevated HSIL risk remained higher in diethylstilbestrol-exposed women, after accounting for frequency of cervical cancer screening. Compared with unexposed women, HSIL risk was higher among women with ea...
Source: Obstetrics and Gynecology - February 29, 2024 Category: OBGYN Authors: Rebecca Troisi Kimberly Bertrand Elizabeth E Hatch William C Strohsnitter Kjersti Aagaard Stanley J Robboy Gretchen Gierach Linda Titus Source Type: research