Liver fat as a dietary target by Chinese Medical Nutrition Therapy (CMNT) diet for treating type 2 diabetes with non-alcoholic fatty liver disease: study protocol for a randomised controlled trial
This study aims to investigate the long-term effect of a Chinese Medical Nutrition Therapy (CMNT) diet accompanied by intermittent energy restriction on reducing liver fat and glycated haemoglobin (HbA1c) in patients with type 2 diabetes and NAFLD.
Methods and analysis
This is a multicentre two-armed parallel randomised controlled trial study. 120 participants with type 2 diabetes and NAFLD will be recruited from the physical examination centres of multiple hospitals in China. Participants will be randomly allocated 1:1 to either the CMNT group or the usual care group. The CMNT group will be instructed to consume the prov...
Source: BMJ Open - April 29, 2024 Category: General Medicine Authors: Luo, W., Xiao, Z., Yang, X., Wu, R., Li, J., Yu, Z., Guo, S., Nie, B., Liu, D. Tags: Open access, Diabetes and Endocrinology Source Type: research
Financial incentive interventions for smoking cessation among Chinese smokers: study protocol for a cluster randomised controlled trial
Introduction
There is an urgent issue to relieve the burdens caused by tobacco use through feasible and effective smoking cessation interventions, particularly in a middle-income country with less accessible smoking cessation services and high demand for quitting smoking. Financial incentives have shown effective in changing health behaviours, thus needing to test its portability to a wider implementation and effectiveness of increasing smoking cessation rates.
Methods and analysis
This is a three-arm cluster randomised controlled trial. 462 eligible participants will be assigned to 2 financial incentive groups—rewa...
Source: BMJ Open - April 29, 2024 Category: General Medicine Authors: Yang, X., Galarraga, O., Cao, W., Lin, H., Cao, F., Chang, C. Tags: Open access, Smoking and tobacco Source Type: research
Efficacy and safety of seven Chinese patent medicines combined with conventional triple/quadruple therapy for Helicobacter pylori-positive peptic ulcers: a systematic review and network meta-analysis
Conclusion
Among the combination therapies with the CPMs, Jianweiyuyang+T/Q might be the most favourable option for H. pylori-positive peptic ulcers, followed by Kangfuxin+T/Q. Considering the limited quantity and quality of the included RCTs, the results should be interpreted with caution.
PROSPERO registration number
CRD42022327687. (Source: BMJ Open)
Source: BMJ Open - April 29, 2024 Category: General Medicine Authors: Jiang, Z., Deng, B., Zhang, Y., Li, Y., Yu, Z., Deng, H., Chen, Y. Tags: Open access, Gastroenterology and hepatology Source Type: research
Hepatitis C virus subtype diversity and transmission clusters characteristics among drug users in Zhuhai, South China
Hepatitis C virus (HCV) infection poses a major public health challenge globally, especially among injecting drug users. China has the world ’s largest burden of HCV infections. However, little is known about t... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - April 29, 2024 Category: Infectious Diseases Authors: Hongxia Li, Huitao Huang, Wenyan Huang, Man Du, Dongling Long, Guangxian Xu, Wenhua Mei and Kaisong Huang Tags: Research Source Type: research
Unveiling the ventral morphology of a rare early Cambrian great appendage arthropod from the Chengjiang biota of China
The early Cambrian arthropod clade Megacheira, also referred to as great appendage arthropods, comprised a group of diminutive and elongated predators during the early Palaeozoic era, around 518 million years ... (Source: BMC Biology)
Source: BMC Biology - April 29, 2024 Category: Biology Authors: Michel Schmidt, Xianguang Hou, Huijuan Mai, Guixian Zhou, Roland R. Melzer, Xilin Zhang and Yu Liu Tags: Research article Source Type: research
Viruses, Vol. 16, Pages 706: Additional Insertion of gC Gene Triggers Better Immune Efficacy of TK/gI/gE-Deleted Pseudorabies Virus in Mice
en Luo
Chunmei Ju
In recent years, pseudorabies virus (PRV) variants have resulted in an epidemic in swine herds and huge economic losses in China. Therefore, it is essential to develop an efficacious vaccine against the spread of PRV variants. Here, the triple-gene-deletion virus and the triple-gene-deletion plus gC virus were constructed by homologous recombination (HR). And then, their growth capacity, proliferation ability, and immune efficacy were evaluated. The results showed that the growth kinetics of the recombinant viruses were similar to those of the parental strain PRV-AH. Compared with the triple-gene-de...
Source: Viruses - April 29, 2024 Category: Virology Authors: Zhuoyun Wu Jiahuan Deng Meijing Chen Peiqi Lu Zhibin Yan Xiaoyan Wu Qiuyun Ji Huiying Fan Yongwen Luo Chunmei Ju Tags: Article Source Type: research
Viruses, Vol. 16, Pages 705: Determination and Characterization of Novel Papillomavirus and Parvovirus Associated with Mass Mortality of Chinese Tongue Sole (Cynoglossus semilaevis) in China
This study represents the first report where novel papillomavirus and parvovirus are identified in farmed marine cultured fish, and it provides a basis for further studies on the prevention and treatment of emerging viral diseases. (Source: Viruses)
Source: Viruses - April 29, 2024 Category: Virology Authors: Shuxia Xue Xinrui Liu Yuru Liu Chang Lu Lei Jia Yanguang Yu Houfu Liu Siyu Yang Zhu Zeng Hui Li Jiatong Qin Yuxuan Wang Jinsheng Sun Tags: Article Source Type: research
Genetic polymorphism in the Han populations from Shandong province using a novel system based on 41 Y-STRs and 3 Y-InDels
Volume 56, Issue sup1, May 2024 . (Source: Australian Journal of Forensic Sciences)
Source: Australian Journal of Forensic Sciences - April 29, 2024 Category: Forensic Medicine Authors: Min LiGuofang CaiChen FangPeng ZhouDeping MengXiaoqun XuChunjiang YuChengtao LiJiangwei Yana Shanghai Key Lab of Forensic Medicine, Key Lab of Forensic Science, Ministry of Justice, China (Academy of Forensic Science), Shanghai, P. R. Chinab School of Cli Source Type: research
Two interesting banknote cases
Volume 56, Issue sup1, May 2024 . (Source: Australian Journal of Forensic Sciences)
Source: Australian Journal of Forensic Sciences - April 29, 2024 Category: Forensic Medicine Authors: C. M. PangQuestioned Documents Section, Forensic Science Division, Government Laboratory, Hong Kong Special Administrative Region, People ’s Republic of China Source Type: research
Superconductivity hunt gets boost from China's $220 million physics 'playground'
Nature, Published online: 29 April 2024; doi:10.1038/d41586-024-01192-4From extreme cold to strong magnets and high pressures, the Synergetic Extreme Condition User Facility (SECUF) provides conditions for researching these potential wonder materials. (Source: Nature AOP)
Source: Nature AOP - April 29, 2024 Category: Research Authors: Gemma Conroy Source Type: research
Effect of Apheresis Plasma Donation on Plasma Uric Acid Levels, the Lipid Profile, and Major Plasma Proteins in Plasma Donors in China: A Multicenter, Prospective Cohort Study
Abnormal plasma uric acid (UA) levels, the lipid profile, and plasma proteins in blood are associated with a range of adverse health outcomes. This multicenter, prospective cohort study aimed to determine the possible effects of multiple apheresis plasma donations on plasma UA levels, the lipid profile, and major proteins in plasma donors. Participants were enrolled from 1 April 2021 to 31 August 2022. When their plasma UA (men:>420 µmol/L, women:>360 µmol/L) and/or lipid levels (total cholesterol [TC]: ≥6.2mmol/L, triglycerides [TGs]: ≥2.3mmol/L, low-density lipoprotein cholesterol: ≥4.1mmol/L, or high-density lip...
Source: Transfusion and Apheresis Science - April 29, 2024 Category: Hematology Authors: Qing Liu, Fengjuan Liu, Pan Sun, Xi Du, Liyuan Zhu, Jun Xu, Lu Cheng, Yaojing Huang, Chunyan Huang, Jielin Chen, Zhibo Wang, Aihong Lu, Yikuan Zhu, Huan Huang, Junli Huang, Jufeng Pan, Li Ma, Zongkui Wang, Changqing Li Source Type: research
Health risk analysis of nitrate in groundwater in Shanxi Province, China: A case study of the Datong Basin
J Water Health. 2024 Apr;22(4):701-716. doi: 10.2166/wh.2024.320. Epub 2024 Mar 18.ABSTRACTIn order to identify and effectively control the impact of NO3- pollution on human health, on the basis of investigation, sampling, analysis and testing, statistical analysis software (SPSS19), groundwater pollution analysis software, Nemera comprehensive index method, correlation analysis method and human health risk assessment model are applied for analysis and research. The results indicate that the groundwater in the study area is mainly Class II water, with overall good water quality. The main influencing factors for producing C...
Source: Journal of Water and Health - April 28, 2024 Category: Environmental Health Authors: Qifa Sun Guohui Lang Tao Liu Zhijie Liu Jilin Zheng Source Type: research
Short-Chain Carboxylates Facilitate the Counting of Yeasts in Sub-High Temperature Daqu
In this study, short-chain carboxylates (C1-C6) were added to the culture medium at various pH conditions to investigate their effects on the growth of molds and yeasts. The results demonstrated distinct inhibitory effects of the short-chain carboxylates, depending on both pH and concentration. Several tested short-chain carboxylates effectively suppressed mold growth on agar plates while leaving yeast growth unaffected. This suggests a simple and feasible method for enhancing the efficiency of yeast isolation and counting in Daqu. Such an approach is valuable for studying yeasts in diverse and complex habitats.PMID:386784...
Source: Polish Journal of Microbiology - April 28, 2024 Category: Microbiology Authors: Zhiqiang Ren Juan Xie Tuoxian Tang Zhiguo Huang Source Type: research
Inhibition of PARP1 improves cardiac function after myocardial infarction via up-regulated NLRC5
Chem Biol Interact. 2024 Apr 26;395:111010. doi: 10.1016/j.cbi.2024.111010. Online ahead of print.ABSTRACTThe incidence and mortality rate of myocardial infarction are increasing per year in China. The polarization of macrophages towards the classically activated macrophages (M1) phenotype is of utmost importance in the progression of inflammatory stress subsequent to myocardial infarction. Poly (ADP-ribose) polymerase 1(PARP1) is the ubiquitous and best characterized member of the PARP family, which has been reported to support macrophage polarization towards the pro-inflammatory phenotype. Yet, the role of PARP1 in myoca...
Source: Chemico-Biological Interactions - April 28, 2024 Category: Molecular Biology Authors: Jia-Ming Luo Hong-Bin Lin Ya-Qian Weng Ying-Hui Lin Lu-Ying Lai Ji Li Feng-Xian Li Shi-Yuan Xu Hong-Fei Zhang Wei Zhao Source Type: research
Exploring Efficient Strategies for Air Quality Improvement in China Based on Its Regional Characteristics and Interannual Evolution of PM < sub > 2.5 < /sub > Pollution
Environ Res. 2024 Apr 26:119009. doi: 10.1016/j.envres.2024.119009. Online ahead of print.ABSTRACTFine particulate matter (PM2.5) harms human health and hinders normal human life. Considering the serious complexity and obvious regional characteristics of PM2.5 pollution, it is urgent to fill in the comprehensive overview of regional characteristics and interannual evolution of PM2.5. This review studied the PM2.5 pollution in six typical areas between 2014 and 2022 based on the data published by the Chinese government and nearly 120 relevant literature. We analyzed and compared the characteristics of interannual and quarte...
Source: Environmental Research - April 28, 2024 Category: Environmental Health Authors: Xin-Ze Geng Jia-Tian Hu Zi-Meng Zhang Zhi-Ling Li Chong-Jun Chen Yu-Long Wang Zhi-Qing Zhang Ying-Jie Zhong Source Type: research
