Bronchopulmonary Dysplasia Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Patent Ductus Arteriosus and Lung MRI Phenotype in Moderate and Severe Bronchopulmonary Dysplasia-Pulmonary Hypertension
CONCLUSIONS: In infants with moderate or severe BPD, prolonged exposure to hsPDA is associated with BPD severity, PH-PVD, and increased parenchymal lung disease by MRI.PMID:38568735 | DOI:10.1164/rccm.202310-1733OC (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 3, 2024 Category: Respiratory Medicine Authors: Kurt R Bjorkman Kimberley G Miles Laura E Bellew Kristin A Schneider S Melissa Magness Nara S Higano Nicholas J Ollberding X Hoyos Cordon Russel M Hirsch Erik B Hysinger Jason C Woods Paul J Critser Source Type: research

Patent Ductus Arteriosus and Lung MRI Phenotype in Moderate and Severe Bronchopulmonary Dysplasia-Pulmonary Hypertension
CONCLUSIONS: In infants with moderate or severe BPD, prolonged exposure to hsPDA is associated with BPD severity, PH-PVD, and increased parenchymal lung disease by MRI.PMID:38568735 | DOI:10.1164/rccm.202310-1733OC (Source: Respiratory Care)
Source: Respiratory Care - April 3, 2024 Category: Respiratory Medicine Authors: Kurt R Bjorkman Kimberley G Miles Laura E Bellew Kristin A Schneider S Melissa Magness Nara S Higano Nicholas J Ollberding X Hoyos Cordon Russel M Hirsch Erik B Hysinger Jason C Woods Paul J Critser Source Type: research

Patent Ductus Arteriosus and Lung MRI Phenotype in Moderate and Severe Bronchopulmonary Dysplasia-Pulmonary Hypertension
CONCLUSIONS: In infants with moderate or severe BPD, prolonged exposure to hsPDA is associated with BPD severity, PH-PVD, and increased parenchymal lung disease by MRI.PMID:38568735 | DOI:10.1164/rccm.202310-1733OC (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - April 3, 2024 Category: Intensive Care Authors: Kurt R Bjorkman Kimberley G Miles Laura E Bellew Kristin A Schneider S Melissa Magness Nara S Higano Nicholas J Ollberding X Hoyos Cordon Russel M Hirsch Erik B Hysinger Jason C Woods Paul J Critser Source Type: research

Epigenetic modifications in the development of bronchopulmonary dysplasia: a review
Pediatr Res. 2024 Apr 3. doi: 10.1038/s41390-024-03167-7. Online ahead of print.ABSTRACTWhile perinatal medicine advancements have bolstered survival outcomes for premature infants, bronchopulmonary dysplasia (BPD) continues to threaten their long-term health. Gene-environment interactions, mediated by epigenetic modifications such as DNA methylation, histone modification, and non-coding RNA regulation, take center stage in BPD pathogenesis. Recent discoveries link methylation variations across biological pathways with BPD. Also, the potential reversibility of histone modifications fuels new treatment avenues. The review a...
Source: Cell Research - April 3, 2024 Category: Cytology Authors: Lichuan Wang Jun Xiao Bohan Zhang Ana Hou Source Type: research

Epigenetic modifications in the development of bronchopulmonary dysplasia: a review
Pediatr Res. 2024 Apr 3. doi: 10.1038/s41390-024-03167-7. Online ahead of print.ABSTRACTWhile perinatal medicine advancements have bolstered survival outcomes for premature infants, bronchopulmonary dysplasia (BPD) continues to threaten their long-term health. Gene-environment interactions, mediated by epigenetic modifications such as DNA methylation, histone modification, and non-coding RNA regulation, take center stage in BPD pathogenesis. Recent discoveries link methylation variations across biological pathways with BPD. Also, the potential reversibility of histone modifications fuels new treatment avenues. The review a...
Source: Pediatric Research - April 3, 2024 Category: Pediatrics Authors: Lichuan Wang Jun Xiao Bohan Zhang Ana Hou Source Type: research

Patent Ductus Arteriosus and Lung MRI Phenotype in Moderate and Severe Bronchopulmonary Dysplasia-Pulmonary Hypertension
CONCLUSIONS: In infants with moderate or severe BPD, prolonged exposure to hsPDA is associated with BPD severity, PH-PVD, and increased parenchymal lung disease by MRI.PMID:38568735 | DOI:10.1164/rccm.202310-1733OC (Source: Respiratory Care)
Source: Respiratory Care - April 3, 2024 Category: Respiratory Medicine Authors: Kurt R Bjorkman Kimberley G Miles Laura E Bellew Kristin A Schneider S Melissa Magness Nara S Higano Nicholas J Ollberding X Hoyos Cordon Russel M Hirsch Erik B Hysinger Jason C Woods Paul J Critser Source Type: research

Nutritional support during the first week for infants with bronchopulmonary dysplasia and respiratory distress: a multicenter cohort study in China
Bronchopulmonary dysplasia (BPD) is a major complication affecting the survival rate and long-term outcomes of preterm infants. A large, prospective, multicenter cohort study was conducted to evaluate early nu... (Source: BMC Pediatrics)
Source: BMC Pediatrics - April 3, 2024 Category: Pediatrics Authors: Huijia Lin, Guannan Bai, Jiajing Ge, Xuefeng Chen, Xinyu He, Xiaolu Ma, Liping Shi, Lizhong Du and Zheng Chen Tags: Research Source Type: research

Single-Cell RNA Sequencing Reveals Repair Features of Human Umbilical Cord Mesenchymal Stromal Cells
CONCLUSIONS: UC-MSCs with a progenitor-like transcriptome, but not with a fibroblast-like transcriptome, provide lung protection in experimental BPD. High expression of major histocompatibility complex class I is associated with reduced therapeutic benefit. scRNA-seq may be useful to identify subsets of MSCs with superior repair capacity for clinical application.PMID:38564376 | DOI:10.1164/rccm.202310-1975OC (Source: Respiratory Care)
Source: Respiratory Care - April 2, 2024 Category: Respiratory Medicine Authors: Chan èle Cyr-Depauw David P Cook Ivana Mi žik Flore Lesage Arul Vadivel Laurent Renesme Yupu Deng Shumei Zhong Pauline Bardin Liqun Xu Marius A M öbius Jenny Marzahn Daniel Freund Duncan J Stewart Barbara C Vanderhyden Mario R üdiger Bernard Th ébaud Source Type: research

Single-Cell RNA Sequencing Reveals Repair Features of Human Umbilical Cord Mesenchymal Stromal Cells
CONCLUSIONS: UC-MSCs with a progenitor-like transcriptome, but not with a fibroblast-like transcriptome, provide lung protection in experimental BPD. High expression of major histocompatibility complex class I is associated with reduced therapeutic benefit. scRNA-seq may be useful to identify subsets of MSCs with superior repair capacity for clinical application.PMID:38564376 | DOI:10.1164/rccm.202310-1975OC (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 2, 2024 Category: Respiratory Medicine Authors: Chan èle Cyr-Depauw David P Cook Ivana Mi žik Flore Lesage Arul Vadivel Laurent Renesme Yupu Deng Shumei Zhong Pauline Bardin Liqun Xu Marius A M öbius Jenny Marzahn Daniel Freund Duncan J Stewart Barbara C Vanderhyden Mario R üdiger Bernard Th ébaud Source Type: research

Mesenchymal stromal cell extracellular vesicles improve lung development in mechanically ventilated preterm lambs
CONCLUSIONS: MSC-sEVs improved respiratory system physiology and alveolar formation in mechanically ventilated preterm lambs. MSC-sEVs may be an effective and safe therapy for appropriate functional and structural development of the lung in preterm infants who require mechanical ventilation and are at-risk of developing BPD.PMID:38563994 | DOI:10.1152/ajplung.00349.2023 (Source: Am J Physiol Lung Ce...)
Source: Am J Physiol Lung Ce... - April 2, 2024 Category: Respiratory Medicine Authors: Kurt H Albertine Andrew Rebentisch Elaine Dawson Jakob Van Boerum Emily Major Juraj Štipka Hannah Foreman David Headden Zo ë Vordos Emily Beck Zhengming Wang Haixia Yang Baifeng Yu Mar Janna Dahl Donald M Null Davide Bizzotto Chiara Veneroni Anna Lavizz Source Type: research

Single-Cell RNA Sequencing Reveals Repair Features of Human Umbilical Cord Mesenchymal Stromal Cells
CONCLUSIONS: UC-MSCs with a progenitor-like transcriptome, but not with a fibroblast-like transcriptome, provide lung protection in experimental BPD. High expression of major histocompatibility complex class I is associated with reduced therapeutic benefit. scRNA-seq may be useful to identify subsets of MSCs with superior repair capacity for clinical application.PMID:38564376 | DOI:10.1164/rccm.202310-1975OC (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - April 2, 2024 Category: Intensive Care Authors: Chan èle Cyr-Depauw David P Cook Ivana Mi žik Flore Lesage Arul Vadivel Laurent Renesme Yupu Deng Shumei Zhong Pauline Bardin Liqun Xu Marius A M öbius Jenny Marzahn Daniel Freund Duncan J Stewart Barbara C Vanderhyden Mario R üdiger Bernard Th ébaud Source Type: research

Mesenchymal stromal cell extracellular vesicles improve lung development in mechanically ventilated preterm lambs
CONCLUSIONS: MSC-sEVs improved respiratory system physiology and alveolar formation in mechanically ventilated preterm lambs. MSC-sEVs may be an effective and safe therapy for appropriate functional and structural development of the lung in preterm infants who require mechanical ventilation and are at-risk of developing BPD.PMID:38563994 | DOI:10.1152/ajplung.00349.2023 (Source: American Journal of Physiology. Lung Cellular and Molecular Physiology)
Source: American Journal of Physiology. Lung Cellular and Molecular Physiology - April 2, 2024 Category: Cytology Authors: Kurt H Albertine Andrew Rebentisch Elaine Dawson Jakob Van Boerum Emily Major Juraj Štipka Hannah Foreman David Headden Zo ë Vordos Emily Beck Zhengming Wang Haixia Yang Baifeng Yu Mar Janna Dahl Donald M Null Davide Bizzotto Chiara Veneroni Anna Lavizz Source Type: research

The role of nutritional interventions in the prevention and treatment of chronic lung disease of prematurity
Pediatr Res. 2024 Apr 2. doi: 10.1038/s41390-024-03133-3. Online ahead of print.ABSTRACTChronic lung disease of prematurity or bronchopulmonary dysplasia (BPD) is a common complication of preterm birth. Nutrition may affect incidence and severity of BPD. In this context, the Section on Nutrition, Gastroenterology and Metabolism, the Pulmonary Section of the European Society for Paediatric Research (ESPR) and SPR have joined forces to review the current knowledge on nutritional issues related to BPD. The aim of this narrative review is to discuss the clinical implications for nutritional practice. Nutrient deficiencies may ...
Source: Pediatric Research - April 2, 2024 Category: Pediatrics Authors: Miguel Saenz de Pipaon Leif D Nelin Alison Gehred Madelaine E Rossholt Sissel Moltu Chris Van den Akker Anton H van Kaam Ana S ánchez Minesh Khashu Charles C Roehr Virgilio Carnielli ESPR Nutrition council members Source Type: research