Bronchopulmonary Dysplasia Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Histological Chorioamnionitis Increases the Risk of Bronchopulmonary Dysplasia
Am J Respir Crit Care Med. 2024 Feb 28. doi: 10.1164/rccm.202311-2084LE. Online ahead of print.NO ABSTRACTPMID:38416515 | DOI:10.1164/rccm.202311-2084LE (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - February 28, 2024 Category: Intensive Care Authors: Viral G Jain Nehal A Parikh Matthew A Rysavy Vivek V Shukla Marissa Trotta Alan Jobe Waldemar A Carlo Namasivayam Ambalavanan Source Type: research

Histological Chorioamnionitis Increases the Risk of Bronchopulmonary Dysplasia
Am J Respir Crit Care Med. 2024 Feb 28. doi: 10.1164/rccm.202311-2084LE. Online ahead of print.NO ABSTRACTPMID:38416515 | DOI:10.1164/rccm.202311-2084LE (Source: Respiratory Care)
Source: Respiratory Care - February 28, 2024 Category: Respiratory Medicine Authors: Viral G Jain Nehal A Parikh Matthew A Rysavy Vivek V Shukla Marissa Trotta Alan Jobe Waldemar A Carlo Namasivayam Ambalavanan Source Type: research

Recombinant IGF-1/BP3 protects against intestinal injury in a neonatal mouse NEC model
CONCLUSIONS: Exogenous rhIGF-1/BP3 protects neonatal mice against experimental NEC via multiple mechanisms.IMPACT: Exogenous rhIGF-1/BP3 preserves intestinal microvascular development and integrity, promotes enterocyte proliferation and migration, decreases local and systemic inflammation, and protects neonatal mice against NEC. The article adds pre-clinical evidence of a protective role for rhIGF-1/BP3 on the premature gut. It provides evidence supporting the use of rhIGF1/BP3 in premature neonates to protect against NEC.PMID:38418592 | DOI:10.1038/s41390-024-03069-8 (Source: Pediatric Research)
Source: Pediatric Research - February 28, 2024 Category: Pediatrics Authors: Xiaocai Yan Elizabeth Managlia Galen Carey Norman Barton Xiao-Di Tan Isabelle G De Plaen Source Type: research

A retrospective cohort study on mortality, morbidity, and care practices for 1750 very low birth weight infants, 2016-2021
CONCLUSION: Among VLBW infants born in 2016-2021, the total and in-hospital mortality rates were lower than those of neonates born in 2009-2015. Incidences of NRDS and BPD increased in 2016-2021, which affected the survival rates and long-term prognosis of VLBW.PMID:38404117 | DOI:10.1097/CM9.0000000000002923 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - February 26, 2024 Category: General Medicine Authors: Yang He Meng Zhang Jun Tang Wanxiu Liu Yong Hu Jing Shi Hua Wang Tao Xiong Li Zhang Junjie Ying Dezhi Mu Source Type: research

Impact of Congenital Heart Disease on the Outcomes of Very Low Birth Weight Infants
Conclusion VLBW-CHDs showed higher odds of BPD, sepsis, and mortality than VLBW infants without CHD. Future research should focus on the increased mortality and specific complications encountered by VLBW infants with CHD and implement targeted strategies to address these risks. Key Points [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - February 26, 2024 Category: Perinatology & Neonatology Authors: Chen, Xuxin Bhombal, Shazia Kwiatkowski, David M. Ma, Michael Chock, Valerie Y. Tags: Original Article Source Type: research

Implication of m6A Methylation Regulators in the Immune Microenvironment of Bronchopulmonary Dysplasia
Biochem Genet. 2024 Feb 23. doi: 10.1007/s10528-024-10664-1. Online ahead of print.ABSTRACTN6-methyladenosine (m6A) regulates gene expression and governs many important biological processes. However, the function of m6A in the development of bronchopulmonary dysplasia (BPD) remains poorly characterized. Thus, the purpose of this investigation was to evaluate the effects of m6A RNA methylation regulators on the development of BPD. BPD-related transcriptome data were downloaded from the GEO database. Differentially expressed m6A methylation regulators between BPD and control group were identified. Consensus clustering was co...
Source: Biochemical Genetics - February 23, 2024 Category: Genetics & Stem Cells Authors: Tianping Bao Haiyan Zhu Mengmeng Ma Tingting Sun Jingjing Hu JingYan Li Linxia Cao Huaiping Cheng Zhaofang Tian Source Type: research

Non-invasive ventilation in neonatal care: where are we now?
Survival of extremely preterm infants has improved from enhanced antenatal care and high uptake of antenatal steroids along with early use of surfactant. However, the burden of ventilator-induced lung injury (VILI) and bronchopulmonary dysplasia (BPD) has proportionately increased. Despite a greater understanding of pulmonary graphics and advances in neonatal ventilation techniques such as volume-targeted ventilation, lung morbidities remain high. Since the advent of CPAP in the early 70's, the re have been several attempts to expand the non-invasive ventilation (NIV) techniques to improve survival and reduce morbidity. ...
Source: Paediatrics and Child Health - February 21, 2024 Category: Pediatrics Authors: Tayyaba Yasmeen, Prashant Mallya, Sundaram Janakiraman Tags: Symposium: neonatology Source Type: research

Neurodevelopmental outcomes of preterm neonates receiving rescue inhaled nitric oxide in the first week of age: a cohort study
Conclusions In preterm neonates <29 weeks GA with HRF, rescue iNO use was not associated with worse neurodevelopmental outcomes among survivors who were assessed at 18–24 months CA. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - February 19, 2024 Category: Perinatology & Neonatology Authors: Gurram Venkata, S. K. R., Lodha, A., Hicks, M., Jain, A., Lapointe, A., Makary, H., Kanungo, J., Lee, K.-S., Ye, X., Shah, P. S., Soraisham, A. S., the Canadian Neonatal Network and Canadian Neonatal Follow Up Network Tags: Original research Source Type: research

Identifying effect modifiers of systemic hydrocortisone treatment initiated 7-14 days after birth in ventilated very preterm infants on long-term outcome: secondary analysis of a randomised controlled trial
Conclusion This secondary analysis suggests that in infants <27 weeks’ GA, systemic hydrocortisone may improve the outcome death or NDI, mainly driven by its component death. There was insufficient evidence for other selected candidate effect modifiers. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - February 19, 2024 Category: Perinatology & Neonatology Authors: Halbmeijer, N. M., Sonnaert, M., Swarte, R. M., Koopman-Esseboom, C., van Stuijvenberg, M., Mulder-de Tollenaer, S., Tan, R. N. G. B., Mohns, T., Bruneel, E., Steiner, K., Kramer, B. W., Debeer, A., van Weissenbruch, M. M., Marechal, Y., Blom, H., Plaskie Tags: Original research Source Type: research

Inhaled nitric oxide therapy for preterm infants after 7 days of age: a scoping review protocol
Introduction Inhaled nitric oxide (iNO) use is recommended for persistent pulmonary hypertension of the newborn in term and late preterm infants. Recently, iNO therapy to prevent bronchopulmonary dysplasia (BPD) or rescue for hypoxic respiratory failure and pulmonary hypertension secondary to BPD has increasingly been used in preterm infants after 7 days of postnatal age (in the postacute phase), despite its off-label use. However, the initiation criteria of iNO therapy for preterm infants in the postacute phase are varied. The aim of this scoping review is to identify the clinical and/or echo findings at the initiation of...
Source: BMJ Open - February 19, 2024 Category: General Medicine Authors: Minamitani, Y., Kato, S., Hosokawa, M., Nakashima, T., Iwatani, S., Nakao, A., Suzuki, D., Ota, E., Nakanishi, H. Tags: Open access, Paediatrics Source Type: research

Variability in Practice and Implementation of Oxygen Target Saturation Policies in United States' Neonatal Intensive Care Units
Conclusion Oxygen saturation limits have changed over time with an overall increase in targeted SpO2. However, there remains considerable interunit variation in SpO2 policies. There is a need to achieve consensus to optimize clinical outcomes. Key Points [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - February 19, 2024 Category: Perinatology & Neonatology Authors: Parikh, Pratik White, Robert D. Tolia, Veeral N. Reyburn, Brent Guillory, Charleta Ahmad, Kaashif A. Tags: Original Article Source Type: research