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Inside the NICU: Shining light on the healing power of touch
Abigail underwent open-heart surgery and received care in Boston Children’s Cardiac Intensive Care Unit Traveling through Boston Children’s Neonatal Intensive Care Unit (NICU), you feel the warmth of natural light and a soothing sense of calm. One mom, leaning delicately over her son’s bedside, caresses his forehead and gently whispers a lullaby. Only a few steps away, a father rests in a chair with his tiny son on his chest. Lifesaving technology fills the 24-bed NICU and a reassuring team of specialized physicians, nurses and Child Life Specialists monitor, treat and embrace their delicate patients. Nea...
Source: Thrive, Children's Hospital Boston - November 16, 2017 Category: Pediatrics Authors: Maureen McCarthy Tags: Our Patients’ Stories neonatal intensive care unit NICU Source Type: news

Drexel researchers identify 'master regulator' involved in infant lung damage
(Drexel University) Blocking the micro-RNA miR-34a significantly reduced bronchopulmonary dysplasia (BPD) in mice. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 27, 2017 Category: International Medicine & Public Health Source Type: news

How the lungs of premature babies can undergo damage
(Helmholtz Zentrum M ü nchen - German Research Center for Environmental Health) Premature babies that need ventilation to support their breathing often suffer from a condition known as bronchopulmonary dysplasia. Researchers at the Helmholtz Zentrum M ü nchen, partner in the German Center for Lung Research (DZL), have now discovered a molecular mechanism that plays a key role in the development of the disease. The study has been published in 'EMBO Molecular Medicine'. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 29, 2017 Category: International Medicine & Public Health Source Type: news

What Causes Microcephaly?
Patient Presentation A 5-month-old male came to clinic for his health supervision visit and followup from his neonatal intensive care stay. He was born prematurely at 28 weeks gestation and his stay was complicated by a right sided Grade III intraventricular hemorrhage, a left-sided Grade IV intraventricular hemorrhage, neonatal seizures, respiratory distress and bronchopulmonary dysplasia, retinopathy of prematurity, acute kidney injury that had resolved, possible necrotizing enterocolitis incidents x 2, and herpes simplex encephalitis. He was on home oxygen, a nasogastric feeding tube because of aspiration risk and mult...
Source: PediatricEducation.org - September 25, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Low-Dose Steroids in Preemies: No Adverse Effects on Brain Low-Dose Steroids in Preemies: No Adverse Effects on Brain
Administration of steroid to extremely preterm infants was not associated with adverse neurodevelopmental outcomes and holds promise to prevent bronchopulmonary dysplasia, a new study has found.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 4, 2017 Category: Consumer Health News Tags: Pediatrics News Source Type: news

Enteral DHA Doesn ’ t Cut Preemie Bronchopulmonary Dysplasia Risk
Relative risk of physiological bronchopulmonary dysplasia up for infants born before 29 weeks (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - March 30, 2017 Category: Respiratory Medicine Tags: Pediatrics, Pulmonology, Journal, Source Type: news

DHA Shows No Benefit, Possible Harm, in Preemies DHA Shows No Benefit, Possible Harm, in Preemies
DHA did not lower the risk for bronchopulmonary dysplasia in premature infants and may be associated with increased risk, a new study has found.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 30, 2017 Category: Consumer Health News Tags: Pediatrics News Source Type: news

DHA Fails to Prevent Lung Disease in Preemies (CME/CE)
(MedPage Today) -- Supplementation may have upped risk for bronchopulmonary dysplasia (Source: MedPage Today Pediatrics)
Source: MedPage Today Pediatrics - March 29, 2017 Category: Pediatrics Source Type: news

Hydrocortisone in Managing Bronchopulmonary Dysplasia Hydrocortisone in Managing Bronchopulmonary Dysplasia
Is hydrocortisone a safe and effective treatment option for the prevention and treatment of bronchopulmonary dysplasia?Pediatric Pharmacotherapy (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 3, 2017 Category: Consumer Health News Tags: Pediatrics Journal Article Source Type: news

Adjunctive Therapies in Bronchopulmonary Dysplasia
This article focuses on the pathogenesis of BPD, the adjunctive therapies used in relation to BPD, and the mechanisms of action of these adjunctive therapies. (Source: NeoReviews recent issues)
Source: NeoReviews recent issues - February 28, 2017 Category: Pediatrics Authors: Maduekwe, E., DeCristofaro, J. D. Tags: Pediatric Drug Labeling Update Articles Source Type: news

After 3 Months In The NICU, This Preemie Got A Surprise Homecoming
A Kentucky community came out in full force to support a local family whose daughter was born three months early. Nicole and Blaine Mike of Middlesboro tried to have a baby for 10 years. After unsuccessful fertility treatments, a failed adoption and a painful ectopic pregnancy, they welcomed their daughter, Meredith, on Oct. 24. But they faced another slew of challenges as the baby arrived before her due date and struggled to survive in the NICU. After three months at the University of Tennessee Medical Center in Knoxville, Meredith was finally able to go home. The Mikes made the 90-minute drive back to Middlesboro, where...
Source: Healthy Living - The Huffington Post - February 6, 2017 Category: Consumer Health News Source Type: news

By causing cells to cannibalize themselves, researchers prevent lung injury in mice
Study offers a new solution to prevent Bronchopulmonary Dysplasia (BPD), the most common chronic lung disease in premature infants. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - July 19, 2016 Category: Science Source Type: news

Early echocardiography to study pulmonary hypertension in mouse model of bronchopulmonary dysplasia
(Baylor College of Medicine) Researchers at Baylor College of Medicine who focus on bronchopulmonary dysplasia and pulmonary hypertension, a common lung disease in premature infants, have shown that echocardiography can be used to detect the pulmonary hypertension in neonatal mice at an earlier time point than previously thought. Their report appears today in the International Journal of Chronic Obstructive Pulmonary Disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 15, 2016 Category: Global & Universal Source Type: news

Study: Steroid may heal damaged lungs in newborns
Stephen FellerCHICAGO, April 25 (UPI) -- Hydrocortisone may prevent bronchopulmonary dysplasia, or BPD, in premature newborns given oxygen treatments after birth, according to a recent study. (Source: Health News - UPI.com)
Source: Health News - UPI.com - April 25, 2016 Category: Consumer Health News Source Type: news

Immunization need not be delayed in most preterm infants with BPD
Despite concerns that preterm infants with bronchopulmonary dysplasia (BPD) are more likely to experience respiratory decompensation after immunization than those without BPD, no difference in the... (Source: Pediatric News)
Source: Pediatric News - April 11, 2016 Category: Journals (General) Source Type: news

Immunization need not be delayed in most preterm infants with BPD
Despite concerns that preterm infants with bronchopulmonary dysplasia (BPD) are more likely to experience respiratory decompensation after immunization than those without BPD, no difference in the... (Source: Family Practice News)
Source: Family Practice News - April 11, 2016 Category: Primary Care Source Type: news

Hydrocortisone Curbs Lung Problems in Extremely Preterm InfantsHydrocortisone Curbs Lung Problems in Extremely Preterm Infants
Early low-dose hydrocortisone prompts a significant increase in bronchopulmonary dysplasia-free survival in extremely preterm infants, according to French researchers. Reuters Health Information (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - March 2, 2016 Category: Intensive Care Tags: Pediatrics News Source Type: news

Researchers identify process that causes chronic neonatal lung disease
A key component of the pathogenesis of bronchopulmonary dysplasia (BPD), a devastating and sometimes fatal lung disease that affects premature infants, has been uncovered by researchers. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - January 15, 2016 Category: Science Source Type: news

UT Southwestern researchers identify process that causes chronic neonatal lung disease
(UT Southwestern Medical Center) Pediatric researchers at UT Southwestern Medical Center have identified a key component of the pathogenesis of bronchopulmonary dysplasia (BPD), a devastating and sometimes fatal lung disease that affects premature infants. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - January 15, 2016 Category: Biology Source Type: news

Nutritional Management of the Infant With Severe Bronchopulmonary Dysplasia
This article reviews concepts related to these challenges and provides recommendations for achieving successful nutrition in this population. (Source: NeoReviews recent issues)
Source: NeoReviews recent issues - December 1, 2015 Category: Pediatrics Authors: Curtiss, J., Zhang, H., Griffiths, P., Shepherd, E. G., Lynch, S. Tags: Pediatric Drug Labeling Update Articles Source Type: news

Hydrocortisone effects on neurodevelopment for extremely low birthweight infants
First placebo-controlled study on stress dose hydrocortisone and neurodevelopment shows that higher doses of hydrocortisone are not associated with brain injury or neurodevelopmental impairments, but may not be effective in reducing risk for bronchopulmonary dysplasia (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - September 18, 2015 Category: Science Source Type: news

Hydrocortisone effects on neurodevelopment for extremely low birthweight infants
(Nationwide Children's Hospital) First placebo-controlled study on stress dose hydrocortisone and neurodevelopment shows that higher doses of hydrocortisone are not associated with brain injury or neurodevelopmental impairments, but may not be effective in reducing risk for bronchopulmonary dysplasia (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 18, 2015 Category: Global & Universal Source Type: news

Hair Sample Tests Reveal Underreported Exposure to Tobacco Smoke Among Preemies With Lung Disease - 2/23/15
Public health experts have long known that tobacco smoke exposure (TSE) can be harmful for children with bronchopulmonary dysplasia, a lung disease that often accompanies premature birth. (Source: Johns Hopkins Medicine News)
Source: Johns Hopkins Medicine News - February 23, 2015 Category: Research Source Type: news

Tests reveal under-reported exposure to tobacco smoke among preemies with lung disease
(Johns Hopkins Medicine) Public health experts have long known that tobacco smoke exposure can be harmful for children with bronchopulmonary dysplasia, a lung disease that often accompanies premature birth. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 23, 2015 Category: Global & Universal Source Type: news

What Are Risk Factors for Progression To Severe Disease with Bronchiolitis?
Discussion Bronchiolitis is a clinical disease with following features: begins usually with rhinitis and cough that may progress to also having tachypnea, rales, wheezing and increased work of breathing shown by nasal flaring and/or accessory muscle use. The increased work of breathing may cause problems with feeding and hydration and also with mental status changes. It is usually seen in infants and children
Source: PediatricEducation.org - December 15, 2014 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Revised Article-Bronchopulmonary Dysplasia
Bronchopulmonary dysplasia, or BPD, is a serious lung condition that affects infants. (Source: National Heart, Lung, and Blood Institute Health Topics)
Source: National Heart, Lung, and Blood Institute Health Topics - October 27, 2014 Category: Consumer Health News Source Type: news

Minimally Invasive Surfactant Therapy: An Update
Preterm infants who have respiratory distress syndrome have for many years been managed with a combination of early intubation and exogenous surfactant therapy. It is now recognized that applying continuous positive airway pressure (CPAP) in an extremely preterm infant is a reasonable alternative to early intubation after birth. Meta-analysis of large controlled trials comparing these two approaches suggests a benefit of CPAP, with a small reduction in the risk of the composite outcome of death or bronchopulmonary dysplasia. In the past decade, there has been an upsurge in the use of CPAP as primary therapy for preterm inf...
Source: NeoReviews recent issues - July 1, 2014 Category: Pediatrics Authors: Aguar, M., Vento, M., Dargaville, P. A. Tags: Articles Source Type: news

Preventing lung injuries in very premature babies: Current therapies less effective than expected
A neonatologist at The Children's Hospital of Philadelphia is the senior author of a large new study that found that current non-invasive techniques for respiratory support are less effective than widely assumed, in reducing the incidence of severe lung injury in very premature infants. Neonatologists commonly use non-invasive nasal ventilation instead of mechanical ventilation via a breathing tube, in hopes of avoiding bronchopulmonary dysplasia (BPD)... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 17, 2013 Category: Consumer Health News Tags: Pediatrics / Children's Health Source Type: news

Current therapies less effective than expected in preventing lung injuries in very premature babies
(Children's Hospital of Philadelphia) A neonatologist at The Children's Hospital of Philadelphia is the senior author of a large new study that found that current non-invasive techniques for respiratory support are less effective than widely assumed, in reducing the incidence of severe lung injury in very premature infants. Neonatologists commonly use non-invasive nasal ventilation instead of mechanical ventilation via a breathing tube, in hopes of avoiding the lung disease bronchopulmonary dysplasia. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 14, 2013 Category: Global & Universal Source Type: news

Chorioamnionitis and Bronchopulmonary DysplasiaChorioamnionitis and Bronchopulmonary Dysplasia
This retrospective study examines the correlation between chorioamnionitis and bronchopulmonary dysplasia in preterm infants. Journal of Perinatology : Official Journal of the California Perinatal Association (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 20, 2013 Category: Consumer Health News Tags: Pediatrics Journal Article Source Type: news

Hydrocortisone Safe in Infantile Bronchopulmonary DysplasiaHydrocortisone Safe in Infantile Bronchopulmonary Dysplasia
In preterm infants with bronchopulmonary dysplasia, hydrocortisone does not seem to have adverse effects, according to European researchers. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 5, 2013 Category: Consumer Health News Tags: Pediatrics News Source Type: news

What Causes Spontaneous Pneumothorax?
Discussion “A pneumothorax is a collection of air in the pleural space, and it can be categorized into spontaneous, traumatic or iatrogenic. Spontaneous pneumothorax can be further classified into primary with no clinical evidence of underlying lung disease or secondary due to pre-existing lung disease.” Spontaneous pneumothorax is a condition that is relatively rare in pediatrics. There is a bimodal age distribution – neonates and late adolescence. It is caused by tearing of the visceral pleural. Clinical signs include chest pain, dyspnea, tachycardia, tracheal deviation towards contralateral side, hypot...
Source: PediatricEducation.org - May 20, 2013 Category: Pediatrics Authors: Donna M. D'Alessandro, M.D. Tags: Uncategorized Source Type: news

Noninvasive Strategies for Management of Respiratory Problems in Neonates
Multiple techniques have been developed to provide noninvasive strategies for respiratory support of the newborn that provide positive airway pressure continuously, with or without ventilation cycles, in nonintubated infants. The core physiologic variable is positive airway pressure used clinically as nasal continuous positive airway pressure (CPAP). CPAP can be augmented with intermittent positive pressure breaths that are, or are not, synchronized to the breathing of the infant. Pressures delivered by high-flow nasal cannula are less predictable than those delivered by a CPAP device. A renewed interest in testing and inn...
Source: NeoReviews recent issues - May 1, 2013 Category: Pediatrics Authors: Hillman, N., Jobe, A. H. Tags: Articles Source Type: news

Update on Mechanical Ventilatory Strategies
Mechanical ventilation is essential for survival of many extremely premature infants, but all forms of positive pressure ventilation are to some degree injurious to the lungs. A variety of sophisticated devices are used to provide respiratory support, yet substantial uncertainty remains regarding the optimal ways in which these tools can be used to minimize ventilator-associated lung injury. A good understanding of the unique aspects of respiratory physiology of extremely preterm infants is key to obtaining the greatest benefit from modern ventilator technology. Early lung volume recruitment with adequate end-expiratory pr...
Source: NeoReviews recent issues - May 1, 2013 Category: Pediatrics Authors: Keszler, M. Tags: Articles Source Type: news

Chronic Lung Disease in the Neonate: Past, Present, and Future
Bronchopulmonary dysplasia (BPD), the chronic lung disease (CLD) in the neonate described over 40 years ago, remains a major cause of morbidity and mortality. Because of advances in perinatal care, the disease now appears in infants that are far more immature than in 1967. Soon, infants born at the limit of viability (based on the developmental stage of the lung and its actual incapacity to exchange oxygen and carbon dioxide) will be routinely resuscitated. Neonatologists will then be confronted with new dilemmas (predicting viability) and new therapeutic opportunities. This review takes a quick look at past achievements t...
Source: NeoReviews recent issues - May 1, 2013 Category: Pediatrics Authors: Thebaud, B. Tags: Articles Source Type: news

What Causes Spontaneous Pneumothorax?
Discussion “A pneumothorax is a collection of air in the pleural space, and it can be categorized into spontaneous, traumatic or iatrogenic. Spontaneous pneumothorax can be further classified into primary with no clinical evidence of underlying lung disease or secondary due to pre-existing lung disease.” Spontaneous pneumothorax is a condition that is relatively rare in pediatrics. There is a bimodal age distribution – neonates and late adolescence. It is caused by tearing of the visceral pleural. Clinical signs include chest pain, dyspnea, tachycardia, tracheal deviation towards contralateral side, hypot...
Source: PediatricEducation.org - April 22, 2013 Category: Pediatrics Authors: Donna M. D'Alessandro, M.D. Tags: Uncategorized Source Type: news