Atenolol Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Single-cell Sequence Analysis Combined with Multiple Machine Learning to Identify Markers in Sepsis Patients: LILRA5
AbstractSepsis is a disease with a very high mortality rate, mainly involving an immune-dysregulated response due to bacterial infection. Most studies are currently limited to the whole blood transcriptome level; however, at the single cell level, there is still a great deal unknown about specific cell subsets and disease markers. We obtained 29 peripheral blood single-cell sequencing data, including 66,283 cells from 10 confirmed samples of sepsis infection and 19 healthy samples. Cells related to the sepsis phenotype were identified and characterized by the “scissor” method. The regulatory relationships of sepsis-...
Source: Inflammation - July 22, 2023 Category: Allergy & Immunology Source Type: research

An Update on Impacts of Epigallocatechin Gallate Co-administration in Modulating Pharmacokinetics of Statins, Calcium Channel Blockers, and Beta-blockers
Planta Med DOI: 10.1055/a-2111-7319Brewed green tea, green tea extract, and its primary active compound, epigallocatechin gallate, may interact with drugs and alter the drugʼs therapeutic effectiveness, ultimately leading to therapeutic failure or drug overdose. Several isolated reports have claimed that epigallocatechin gallate is the main active ingredient that causes these effects. While a few studies aimed to uncover evidence of epigallocatechin gallate-drug interactions, no study has thoroughly and collectively reviewed them. Epigallocatechin gallate is a potential cardioprotective agent used by many p...
Source: Planta Medica - July 14, 2023 Category: Drugs & Pharmacology Authors: Siew-Keah, Lee Jie, Tan Hong Ang-Lim, Chua Bin, Liew Kai Yik-Ling, Chew Tags: Reviews Source Type: research

Analyzing microbial communities and their biodegradation of multiple pharmaceuticals in membrane bioreactors
Appl Microbiol Biotechnol. 2023 Jul 12. doi: 10.1007/s00253-023-12677-z. Online ahead of print.ABSTRACTPharmaceuticals are of concern to our planet and health as they can accumulate in the environment. The impact of these biologically active compounds on ecosystems is hard to predict, and information on their biodegradation is necessary to establish sound risk assessment. Microbial communities are promising candidates for the biodegradation of pharmaceuticals such as ibuprofen, but little is known yet about their degradation capacity of multiple micropollutants at higher concentrations (100 mg/L). In this work, microbial c...
Source: Applied Microbiology and Biotechnology - July 12, 2023 Category: Microbiology Authors: Marcel Suleiman Francesca Demaria Cristina Zimmardi Boris Alexander Kolvenbach Philippe Fran çois-Xavier Corvini Source Type: research

Coronary Computed Tomographic Angiography as the Initial Gatekeeper Modality to Identify and Assess the Severity of Atherosclerotic Coronary Artery Disease
66-year-old Bengali male with past medical history of hypertension, hyperlipidemia, and diabetes mellitus type 2 was referred to the cardiology clinic for the evaluation and management of angina pectoris. The patient's symptoms were characterized as exertional chest pressure, which worsened with minimal activity (walking for 5 minutes) and relieved with rest (after 10 minutes) and had been ongoing for the past 4-5 months. His existing medications included atenolol, valsartan, and empagliflozin. Based on his clinical history and his risk factors for ischemic heart disease, he had a high pre-test probability for ischemic hea...
Source: Journal of Clinical Lipidology - July 1, 2023 Category: Lipidology Authors: Loba Alam, Robert Fishberg, Swaminatha Gurudevan Tags: Imaging Source Type: research

Correction to: Long-term neurocognitive functioning of children treated with propranolol or atenolol for infantile hemangioma
(Source: European Journal of Pediatrics)
Source: European Journal of Pediatrics - June 26, 2023 Category: Pediatrics Source Type: research

IJERPH, Vol. 20, Pages 6154: Influence of Manure as a Complex Mixture on Soil Sorption of Pharmaceuticals & mdash;Studies with Selected Chemical Components of Manure
IJERPH, Vol. 20, Pages 6154: Influence of Manure as a Complex Mixture on Soil Sorption of Pharmaceuticals—Studies with Selected Chemical Components of Manure International Journal of Environmental Research and Public Health doi: 10.3390/ijerph20126154 Authors: Sören Thiele-Bruhn Wei Zhang Pharmaceutically active compounds (PhACs) enter soil with organic waste materials such as manure. Such complex substrates differently affect PhACs&rsquo; soil sorption. For the first time, batch experiments were conducted using five selected chemicals as model constituents to elucidate the effects. Urea, phosp...
Source: International Journal of Environmental Research and Public Health - June 16, 2023 Category: Environmental Health Authors: S ören Thiele-Bruhn Wei Zhang Tags: Article Source Type: research

Epac1 participates in β < sub > 1 < /sub > -adrenoreceptor autoantibody-mediated decreased autophagic flux in cardiomyocytes
This study confirmed that Epac1 upregulation is indeed involved β1-AA-induced decreased cardiomyocyte autophagy through CE3F4 pretreatment, Epac1 siRNA transfection, western blot and immunofluorescence methods. On this basis, we constructed β1-AR and β2-AR knockout mice, and used receptor knockout mice, β1-AR selective blocker (atenolol), and the β2-AR/Gi-biased agonist ICI 118551 to show that β1-AA upregulated Epac1 expression through β1-AR and β2-AR to inhibit autophagy, and biased activation of β2-AR/Gi signaling downregulated myocardial Epac1 expression to reverse β1-AA-induced myocardial autophagy inhibition...
Source: Biochimica et Biophysica Acta - June 14, 2023 Category: Biochemistry Authors: Yang Li Yuan Tian Shu Shi Xiaohong Hou Haihu Hao Mingxia Ma Na Ning Yuan Yuan Xiaohui Wang Huirong Liu Li Wang Source Type: research

Structural and performance variation of PES/PVDF membranes after exposure to the pretreated feed water of CECs
In this study, the removal efficiency of chemicals of emerging concerns (CECs) was evaluated under exposure to various doses of UV/H2O2-based oxidation processes in combination with membrane filtration for three cleaning cycles. Polyethersulphone (PES) and polyvinylidene fluoride (PVDF) materials based membranes were used for this study. The chemical cleaning of the membranes was performed by immersion of the membranes into 1 N HCl followed by adding 3000 mg.L-1 NaOCl for 1hr. Degradation and filtration performance was evaluated using Liquid Chromatography with tandem mass spectrometry (LC-MS/MS) and total organic carbon (...
Source: Chemosphere - June 9, 2023 Category: Chemistry Authors: Jun Young Kim Kang Hoon Lee Jae Won Lee Imtiaz Afzal Khan Jong-Oh Kim Source Type: research

Insight into the synergistic mechanism of sonolysis and sono-induced BiFeO < sub > 3 < /sub > nanorods piezocatalysis in atenolol degradation: Ultrasonic parameters, ROS and degradation pathways
Chemosphere. 2023 May 30:139084. doi: 10.1016/j.chemosphere.2023.139084. Online ahead of print.ABSTRACTHerein, BiFeO3 nanorods (BFO NRs) was synthesized as the piezoelectric catalyst. The synergistic mechanism of sonolysis and sono-induced BFO-piezocatalysis in atenolol degradation was revealed and the effect of ultrasonic parameters on it was investigated for the first time. The results indicated that 100 kHz was the optimal frequency for the sonolytic and sono-piezocatalytic degradation of atenolol in ultrasound/BFO nanorods (US/BFO NRs) system, with the highest synergistic coefficient of 3.43. The piezoelectric potentia...
Source: Chemosphere - June 1, 2023 Category: Chemistry Authors: Mingjian Hong Juanjuan Yao Fanhui Rao Zihan Chen Naiyun Gao Zhi Zhang Wenchao Jiang Source Type: research