Β-blockers activate autophagy on infantile hemangioma-derived endothelial cells in vitro
CONCLUSION: Our data suggest that autophagy may be ascribed among the mechanisms of action of β-blockers suggesting new mechanistic insights on the potential therapeutic application of this class of drugs in pathologic conditions involving uncontrolled angiogenesis.PMID:36103993 | DOI:10.1016/j.vph.2022.107110 (Source: Vascular Pharmacology)
Source: Vascular Pharmacology - September 14, 2022 Category: Drugs & Pharmacology Authors: Bruno Lorusso Giuseppe Cerasoli Angela Falco Caterina Frati Gallia Graiani Denise Madeddu Antonella Nogara Emilia Corradini Giovanni Roti Elisa Cerretani Andrea Gherli Mariafrancesca Caputi Letizia Gnetti Francesco Paolo Pilato Federico Quaini Costanza La Source Type: research
Β-blockers activate autophagy on infantile hemangioma-derived endothelial cells in vitro
CONCLUSION: Our data suggest that autophagy may be ascribed among the mechanisms of action of β-blockers suggesting new mechanistic insights on the potential therapeutic application of this class of drugs in pathologic conditions involving uncontrolled angiogenesis.PMID:36103993 | DOI:10.1016/j.vph.2022.107110 (Source: Vascular Pharmacology)
Source: Vascular Pharmacology - September 14, 2022 Category: Drugs & Pharmacology Authors: Bruno Lorusso Giuseppe Cerasoli Angela Falco Caterina Frati Gallia Graiani Denise Madeddu Antonella Nogara Emilia Corradini Giovanni Roti Elisa Cerretani Andrea Gherli Mariafrancesca Caputi Letizia Gnetti Francesco Paolo Pilato Federico Quaini Costanza La Source Type: research
Β-blockers activate autophagy on infantile hemangioma-derived endothelial cells in vitro
CONCLUSION: Our data suggest that autophagy may be ascribed among the mechanisms of action of β-blockers suggesting new mechanistic insights on the potential therapeutic application of this class of drugs in pathologic conditions involving uncontrolled angiogenesis.PMID:36103993 | DOI:10.1016/j.vph.2022.107110 (Source: Vascular Pharmacology)
Source: Vascular Pharmacology - September 14, 2022 Category: Drugs & Pharmacology Authors: Bruno Lorusso Giuseppe Cerasoli Angela Falco Caterina Frati Gallia Graiani Denise Madeddu Antonella Nogara Emilia Corradini Giovanni Roti Elisa Cerretani Andrea Gherli Mariafrancesca Caputi Letizia Gnetti Francesco Paolo Pilato Federico Quaini Costanza La Source Type: research
Β-blockers activate autophagy on infantile hemangioma-derived endothelial cells in vitro
CONCLUSION: Our data suggest that autophagy may be ascribed among the mechanisms of action of β-blockers suggesting new mechanistic insights on the potential therapeutic application of this class of drugs in pathologic conditions involving uncontrolled angiogenesis.PMID:36103993 | DOI:10.1016/j.vph.2022.107110 (Source: Vascular Pharmacology)
Source: Vascular Pharmacology - September 14, 2022 Category: Drugs & Pharmacology Authors: Bruno Lorusso Giuseppe Cerasoli Angela Falco Caterina Frati Gallia Graiani Denise Madeddu Antonella Nogara Emilia Corradini Giovanni Roti Elisa Cerretani Andrea Gherli Mariafrancesca Caputi Letizia Gnetti Francesco Paolo Pilato Federico Quaini Costanza La Source Type: research
Β-blockers activate autophagy on infantile hemangioma-derived endothelial cells in vitro
CONCLUSION: Our data suggest that autophagy may be ascribed among the mechanisms of action of β-blockers suggesting new mechanistic insights on the potential therapeutic application of this class of drugs in pathologic conditions involving uncontrolled angiogenesis.PMID:36103993 | DOI:10.1016/j.vph.2022.107110 (Source: Vascular Pharmacology)
Source: Vascular Pharmacology - September 14, 2022 Category: Drugs & Pharmacology Authors: Bruno Lorusso Giuseppe Cerasoli Angela Falco Caterina Frati Gallia Graiani Denise Madeddu Antonella Nogara Emilia Corradini Giovanni Roti Elisa Cerretani Andrea Gherli Mariafrancesca Caputi Letizia Gnetti Francesco Paolo Pilato Federico Quaini Costanza La Source Type: research
Β-blockers activate autophagy on infantile hemangioma-derived endothelial cells in vitro
CONCLUSION: Our data suggest that autophagy may be ascribed among the mechanisms of action of β-blockers suggesting new mechanistic insights on the potential therapeutic application of this class of drugs in pathologic conditions involving uncontrolled angiogenesis.PMID:36103993 | DOI:10.1016/j.vph.2022.107110 (Source: Vascular Pharmacology)
Source: Vascular Pharmacology - September 14, 2022 Category: Drugs & Pharmacology Authors: Bruno Lorusso Giuseppe Cerasoli Angela Falco Caterina Frati Gallia Graiani Denise Madeddu Antonella Nogara Emilia Corradini Giovanni Roti Elisa Cerretani Andrea Gherli Mariafrancesca Caputi Letizia Gnetti Francesco Paolo Pilato Federico Quaini Costanza La Source Type: research
Β-blockers activate autophagy on infantile hemangioma-derived endothelial cells in vitro
CONCLUSION: Our data suggest that autophagy may be ascribed among the mechanisms of action of β-blockers suggesting new mechanistic insights on the potential therapeutic application of this class of drugs in pathologic conditions involving uncontrolled angiogenesis.PMID:36103993 | DOI:10.1016/j.vph.2022.107110 (Source: Vascular Pharmacology)
Source: Vascular Pharmacology - September 14, 2022 Category: Drugs & Pharmacology Authors: Bruno Lorusso Giuseppe Cerasoli Angela Falco Caterina Frati Gallia Graiani Denise Madeddu Antonella Nogara Emilia Corradini Giovanni Roti Elisa Cerretani Andrea Gherli Mariafrancesca Caputi Letizia Gnetti Francesco Paolo Pilato Federico Quaini Costanza La Source Type: research
Β-blockers activate autophagy on infantile hemangioma-derived endothelial cells in vitro
CONCLUSION: Our data suggest that autophagy may be ascribed among the mechanisms of action of β-blockers suggesting new mechanistic insights on the potential therapeutic application of this class of drugs in pathologic conditions involving uncontrolled angiogenesis.PMID:36103993 | DOI:10.1016/j.vph.2022.107110 (Source: Vascular Pharmacology)
Source: Vascular Pharmacology - September 14, 2022 Category: Drugs & Pharmacology Authors: Bruno Lorusso Giuseppe Cerasoli Angela Falco Caterina Frati Gallia Graiani Denise Madeddu Antonella Nogara Emilia Corradini Giovanni Roti Elisa Cerretani Andrea Gherli Mariafrancesca Caputi Letizia Gnetti Francesco Paolo Pilato Federico Quaini Costanza La Source Type: research
Diverse pharmacological properties, trial results, comorbidity prescribing and neural pathophysiology suggest European hypertension guideline downgrading of beta-blockers is not justified
Blood Press. 2022 Dec;31(1):210-224. doi: 10.1080/08037051.2022.2110858.ABSTRACTBeta-blockers have solid documentation in preventing cardiovascular complications in the treatment of hypertension; atenolol, metoprolol, oxprenolol and propranolol demonstrate proven cardiovascular prevention in hypertension mega-trials. Hypertension is characterised by activation of the sympathetic nervous system from early to late phases, which makes beta-blockers an appropriate treatment seen from a pathophysiological viewpoint, especially in patients with an elevated heart rate. Beta-blockers represent a heterogenous class of drugs with re...
Source: Blood Pressure - August 27, 2022 Category: Hematology Authors: Murray Esler Sverre E Kjeldsen Atul Pathak Guido Grassi Reinhold Kreutz Giuseppe Mancia Source Type: research
