Β-blockers activate autophagy on infantile hemangioma-derived endothelial cells in vitro

CONCLUSION: Our data suggest that autophagy may be ascribed among the mechanisms of action of β-blockers suggesting new mechanistic insights on the potential therapeutic application of this class of drugs in pathologic conditions involving uncontrolled angiogenesis.PMID:36103993 | DOI:10.1016/j.vph.2022.107110

Source: Vascular Pharmacology - September 14, 2022 Category: Drugs & Pharmacology Authors: Bruno Lorusso Giuseppe Cerasoli Angela Falco Caterina Frati Gallia Graiani Denise Madeddu Antonella Nogara Emilia Corradini Giovanni Roti Elisa Cerretani Andrea Gherli Mariafrancesca Caputi Letizia Gnetti Francesco Paolo Pilato Federico Quaini Costanza La Source Type: research