Prognostic Factors for Long-term Aesthetic Outcome of Infantile Haemangioma Treated with Beta-blockers
Acta Derm Venereol. 2023 Aug 30;103:adv5286. doi: 10.2340/actadv.v103.5286.ABSTRACTParents of infants treated with beta-blockers for infantile haemangioma are often concerned about the long-term aesthetic outcome. This cross-sectional study assessed the influence on the long-term aesthetic outcome of characteristics of the infantile haemangioma, the beta-blocker treatment, and the infant. The study included 103 children aged 6-12 years, treated with beta-blockers (propranolol or atenolol) for infantile haemangioma during infancy (age at treatment initiation ≤1 year) for ≥6 months. Dermatologists and parents scored the ...
Source: Acta Dermato-Venereologica - August 31, 2023 Category: Dermatology Authors: Mireille M Hermans Suzanne G M A Pasmans Marlies De Graaf Avi ël Ragamin Elodie J Mendels Johannes M P J Breur Hester R Langeveld Martine F Raphael Peter C J De Laat Saskia N De Wildt Andr é B Rietman Corstiaan C Breugem Renske Schappin Source Type: research

Prognostic Factors for Long-term Aesthetic Outcome of Infantile Haemangioma Treated with Beta-blockers
Acta Derm Venereol. 2023 Aug 30;103:adv5286. doi: 10.2340/actadv.v103.5286.ABSTRACTParents of infants treated with beta-blockers for infantile haemangioma are often concerned about the long-term aesthetic outcome. This cross-sectional study assessed the influence on the long-term aesthetic outcome of characteristics of the infantile haemangioma, the beta-blocker treatment, and the infant. The study included 103 children aged 6-12 years, treated with beta-blockers (propranolol or atenolol) for infantile haemangioma during infancy (age at treatment initiation ≤1 year) for ≥6 months. Dermatologists and parents scored the ...
Source: Acta Derm Venereol A... - August 31, 2023 Category: Dermatology Authors: Mireille M Hermans Suzanne G M A Pasmans Marlies De Graaf Avi ël Ragamin Elodie J Mendels Johannes M P J Breur Hester R Langeveld Martine F Raphael Peter C J De Laat Saskia N De Wildt Andr é B Rietman Corstiaan C Breugem Renske Schappin Source Type: research

Prognostic Factors for Long-term Aesthetic Outcome of Infantile Haemangioma Treated with Beta-blockers
Acta Derm Venereol. 2023 Aug 30;103:adv5286. doi: 10.2340/actadv.v103.5286.ABSTRACTParents of infants treated with beta-blockers for infantile haemangioma are often concerned about the long-term aesthetic outcome. This cross-sectional study assessed the influence on the long-term aesthetic outcome of characteristics of the infantile haemangioma, the beta-blocker treatment, and the infant. The study included 103 children aged 6-12 years, treated with beta-blockers (propranolol or atenolol) for infantile haemangioma during infancy (age at treatment initiation ≤1 year) for ≥6 months. Dermatologists and parents scored the ...
Source: Acta Dermato-Venereologica - August 31, 2023 Category: Dermatology Authors: Mireille M Hermans Suzanne G M A Pasmans Marlies De Graaf Avi ël Ragamin Elodie J Mendels Johannes M P J Breur Hester R Langeveld Martine F Raphael Peter C J De Laat Saskia N De Wildt Andr é B Rietman Corstiaan C Breugem Renske Schappin Source Type: research

Prognostic Factors for Long-term Aesthetic Outcome of Infantile Haemangioma Treated with Beta-blockers
Acta Derm Venereol. 2023 Aug 30;103:adv5286. doi: 10.2340/actadv.v103.5286.ABSTRACTParents of infants treated with beta-blockers for infantile haemangioma are often concerned about the long-term aesthetic outcome. This cross-sectional study assessed the influence on the long-term aesthetic outcome of characteristics of the infantile haemangioma, the beta-blocker treatment, and the infant. The study included 103 children aged 6-12 years, treated with beta-blockers (propranolol or atenolol) for infantile haemangioma during infancy (age at treatment initiation ≤1 year) for ≥6 months. Dermatologists and parents scored the ...
Source: Acta Derm Venereol A... - August 31, 2023 Category: Dermatology Authors: Mireille M Hermans Suzanne G M A Pasmans Marlies De Graaf Avi ël Ragamin Elodie J Mendels Johannes M P J Breur Hester R Langeveld Martine F Raphael Peter C J De Laat Saskia N De Wildt Andr é B Rietman Corstiaan C Breugem Renske Schappin Source Type: research

Prognostic Factors for Long-term Aesthetic Outcome of Infantile Haemangioma Treated with Beta-blockers
Acta Derm Venereol. 2023 Aug 30;103:adv5286. doi: 10.2340/actadv.v103.5286.ABSTRACTParents of infants treated with beta-blockers for infantile haemangioma are often concerned about the long-term aesthetic outcome. This cross-sectional study assessed the influence on the long-term aesthetic outcome of characteristics of the infantile haemangioma, the beta-blocker treatment, and the infant. The study included 103 children aged 6-12 years, treated with beta-blockers (propranolol or atenolol) for infantile haemangioma during infancy (age at treatment initiation ≤1 year) for ≥6 months. Dermatologists and parents scored the ...
Source: Acta Dermato-Venereologica - August 31, 2023 Category: Dermatology Authors: Mireille M Hermans Suzanne G M A Pasmans Marlies De Graaf Avi ël Ragamin Elodie J Mendels Johannes M P J Breur Hester R Langeveld Martine F Raphael Peter C J De Laat Saskia N De Wildt Andr é B Rietman Corstiaan C Breugem Renske Schappin Source Type: research

Prognostic Factors for Long-term Aesthetic Outcome of Infantile Haemangioma Treated with Beta-blockers
Acta Derm Venereol. 2023 Aug 30;103:adv5286. doi: 10.2340/actadv.v103.5286.ABSTRACTParents of infants treated with beta-blockers for infantile haemangioma are often concerned about the long-term aesthetic outcome. This cross-sectional study assessed the influence on the long-term aesthetic outcome of characteristics of the infantile haemangioma, the beta-blocker treatment, and the infant. The study included 103 children aged 6-12 years, treated with beta-blockers (propranolol or atenolol) for infantile haemangioma during infancy (age at treatment initiation ≤1 year) for ≥6 months. Dermatologists and parents scored the ...
Source: Acta Derm Venereol A... - August 31, 2023 Category: Dermatology Authors: Mireille M Hermans Suzanne G M A Pasmans Marlies De Graaf Avi ël Ragamin Elodie J Mendels Johannes M P J Breur Hester R Langeveld Martine F Raphael Peter C J De Laat Saskia N De Wildt Andr é B Rietman Corstiaan C Breugem Renske Schappin Source Type: research

Renin-angiotensin-aldosterone system inhibitors and mortality risk in elderly patients with atrial fibrillation. Insights from the nationwide START registry
CONCLUSION: A lower mortality risk was found in AF patients on ACE-I/ARBs. Different prescription patterns of antihypertensive drugs between men and women do exist.PMID:37648584 | DOI:10.1016/j.ejim.2023.08.019 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - August 30, 2023 Category: Internal Medicine Authors: Danilo Menichelli Daniela Poli Emilia Antonucci Gualtiero Palareti Pasquale Pignatelli Daniele Pastori START2 Register Investigators Source Type: research

Renin-angiotensin-aldosterone system inhibitors and mortality risk in elderly patients with atrial fibrillation. Insights from the nationwide START registry
CONCLUSION: A lower mortality risk was found in AF patients on ACE-I/ARBs. Different prescription patterns of antihypertensive drugs between men and women do exist.PMID:37648584 | DOI:10.1016/j.ejim.2023.08.019 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - August 30, 2023 Category: Internal Medicine Authors: Danilo Menichelli Daniela Poli Emilia Antonucci Gualtiero Palareti Pasquale Pignatelli Daniele Pastori START2 Register Investigators Source Type: research

Interpreting permeability as a function of free drug fraction: The case studies of cyclodextrins and liposomes
In conclusion, we proved the adequacy and usefulness of our method for calculating free drug fractions in the examined enabling formulations, supporting the validity of the established drug diffusion/permeation theory that the unbounded drug fraction is the main driver for drug permeation across a membrane.PMID:37544334 | DOI:10.1016/j.ejps.2023.106559 (Source: European Journal of Pharmaceutical Sciences)
Source: European Journal of Pharmaceutical Sciences - August 6, 2023 Category: Drugs & Pharmacology Authors: Martina M Tzanova Lisa Nguyen Federica Moretti Mario Grassi Greta Camilla Magnano Dario Voinovich Paul C Stein Marianne Hiorth Massimiliano Pio di Cagno Source Type: research

Interpreting permeability as a function of free drug fraction: The case studies of cyclodextrins and liposomes
In conclusion, we proved the adequacy and usefulness of our method for calculating free drug fractions in the examined enabling formulations, supporting the validity of the established drug diffusion/permeation theory that the unbounded drug fraction is the main driver for drug permeation across a membrane.PMID:37544334 | DOI:10.1016/j.ejps.2023.106559 (Source: European Journal of Pharmaceutical Sciences)
Source: European Journal of Pharmaceutical Sciences - August 6, 2023 Category: Drugs & Pharmacology Authors: Martina M Tzanova Lisa Nguyen Federica Moretti Mario Grassi Greta Camilla Magnano Dario Voinovich Paul C Stein Marianne Hiorth Massimiliano Pio di Cagno Source Type: research

Interpreting permeability as a function of free drug fraction: The case studies of cyclodextrins and liposomes
In conclusion, we proved the adequacy and usefulness of our method for calculating free drug fractions in the examined enabling formulations, supporting the validity of the established drug diffusion/permeation theory that the unbounded drug fraction is the main driver for drug permeation across a membrane.PMID:37544334 | DOI:10.1016/j.ejps.2023.106559 (Source: European Journal of Pharmaceutical Sciences)
Source: European Journal of Pharmaceutical Sciences - August 6, 2023 Category: Drugs & Pharmacology Authors: Martina M Tzanova Lisa Nguyen Federica Moretti Mario Grassi Greta Camilla Magnano Dario Voinovich Paul C Stein Marianne Hiorth Massimiliano Pio di Cagno Source Type: research

Interpreting permeability as a function of free drug fraction: The case studies of cyclodextrins and liposomes
In conclusion, we proved the adequacy and usefulness of our method for calculating free drug fractions in the examined enabling formulations, supporting the validity of the established drug diffusion/permeation theory that the unbounded drug fraction is the main driver for drug permeation across a membrane.PMID:37544334 | DOI:10.1016/j.ejps.2023.106559 (Source: European Journal of Pharmaceutical Sciences)
Source: European Journal of Pharmaceutical Sciences - August 6, 2023 Category: Drugs & Pharmacology Authors: Martina M Tzanova Lisa Nguyen Federica Moretti Mario Grassi Greta Camilla Magnano Dario Voinovich Paul C Stein Marianne Hiorth Massimiliano Pio di Cagno Source Type: research

Molecules, Vol. 28, Pages 5908: Copper (II) Ions Induced Self-Disproportionation of Enantiomers in Capillary Electrophoresis for the Quantification of Atenolol Enantiomers
u Despite the fact that the self-disproportionation of enantiomers (SDE) has been found for several decades and has been widely used in crystallization, sublimation and chromatography for the purification or separation of nonracemic compounds, the phenomenon of SDE in capillary electrophoresis (CE) has never been reported up to now. Here, a new approach to separate enantiomers in CE based on SDE was demonstrated by introducing copper (II) ions into the separation media. The enantiomers of atenolol interact with copper ions to produce positively charged complexes with different electrophoretic mobilities from the single...
Source: Molecules - August 6, 2023 Category: Chemistry Authors: Shaoqiang Hu Tags: Communication Source Type: research

Tizanidine induced hypotension: report of a case and review of literature
CONCLUSION: This patient highlights the need for close monitoring of patients receiving tizanidine co-medication with angiotensin-converting enzyme inhibitors and angiotensin receptor blockers. These drugs have a synergistic effect on reducing the renin-angiotensin-aldosterone system, thereby hypotension and bradycardia.PMID:37489780 | DOI:10.2174/1574886318666230725113855 (Source: Current Drug Safety)
Source: Current Drug Safety - July 25, 2023 Category: Drugs & Pharmacology Authors: Roopali Mahajan Jayantee Kalita Source Type: research

Tizanidine induced hypotension: report of a case and review of literature
CONCLUSION: This patient highlights the need for close monitoring of patients receiving tizanidine co-medication with angiotensin-converting enzyme inhibitors and angiotensin receptor blockers. These drugs have a synergistic effect on reducing the renin-angiotensin-aldosterone system, thereby hypotension and bradycardia.PMID:37489780 | DOI:10.2174/1574886318666230725113855 (Source: Current Drug Safety)
Source: Current Drug Safety - July 25, 2023 Category: Drugs & Pharmacology Authors: Roopali Mahajan Jayantee Kalita Source Type: research