Interpreting permeability as a function of free drug fraction: The case studies of cyclodextrins and liposomes

In conclusion, we proved the adequacy and usefulness of our method for calculating free drug fractions in the examined enabling formulations, supporting the validity of the established drug diffusion/permeation theory that the unbounded drug fraction is the main driver for drug permeation across a membrane.PMID:37544334 | DOI:10.1016/j.ejps.2023.106559
Source: European Journal of Pharmaceutical Sciences - Category: Drugs & Pharmacology Authors: Source Type: research