Effects of hydrocortisone and yohimbine on decision-making under risk - Metz S, Waiblinger-Grigull T, Schulreich S, Chae WR, Otte C, Heekeren HR, Wingenfeld K.
INTRODUCTION: Many studies have investigated the influence of stress on decision-making. However, results are equivocal and the exact role of increased noradrenaline and cortisol after stress remains unclear. Using pharmacological manipulation, we investig... (Source: SafetyLit)
Source: SafetyLit - February 11, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Effect of Vitamin C, Hydrocortisone, and Thiamine vs Hydrocortisone Alone on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock: The VITAMINS Randomized Clinical Trial
RCT (n=216) found that treatment with intravenous vitamin C, hydrocortisone, and thiamine, compared with intravenous hydrocortisone alone, did not significantly improve the duration of time alive and free of vasopressor administration over 7 days. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - February 6, 2020 Category: Consumer Health News Source Type: news

High-Dose IV Vitamin C Does Not Speed Resolution of Septic Shock
FRIDAY, Jan. 24, 2020 -- Treatment with intravenous vitamin C, hydrocortisone, and thiamine does not improve the duration of time alive and vasopressor administration-free compared with intravenous hydrocortisone alone among patients with septic... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 24, 2020 Category: Pharmaceuticals Source Type: news

Vitamin Cocktail for Sepsis Fails; PPI for Stress Ulcer Prevention May Be Risky: ICU Studies Vitamin Cocktail for Sepsis Fails; PPI for Stress Ulcer Prevention May Be Risky: ICU Studies
A major new study of intensive care unit (ICU) patients with septic shock failed to find a benefit of giving an intravenous cocktail of vitamin C, hydrocortisone and thiamine, relative to hydrocortisone alone.Reuters Health Information (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - January 22, 2020 Category: Intensive Care Tags: Critical Care News Source Type: news

Vitamin C-B1-steroid combo linked to lower septic shock mortality in kids
(Ann& Robert H. Lurie Children's Hospital of Chicago) Treating septic shock in children with a combination of intravenous vitamin C, vitamin B1 and hydrocortisone (a commonly used steroid) is associated with lower mortality, according to a study from Ann& Robert H. Lurie Children's Hospital of Chicago. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 21, 2020 Category: International Medicine & Public Health Source Type: news

VITAMINS trial report on vitamin C, hydrocortisone, thiamine for septic shock
(JAMA Network) In this   randomized clinical trial of about 200 patients with septic shock, combination treatment with intravenous vitamin C, hydrocortisone and thiamine compared with intravenous hydrocortisone alone didn't significantly improve the amount of time patients were alive and free of medicines that raise blood pressure (vasopressors) over seven days. The study findings are being released to coincide with presentation at the Critical Care Reviews Meeting 2020 in Belfast, Northern Ireland. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 17, 2020 Category: International Medicine & Public Health Source Type: news

pramoxine and hydrocortisone (Epifoam, Pramosone, Proctofoam HC, Procort, Analpram HC)
Title: pramoxine and hydrocortisone (Epifoam, Pramosone, Proctofoam HC, Procort, Analpram HC)Category: MedicationsCreated: 3/2/2005 12:00:00 AMLast Editorial Review: 11/22/2019 12:00:00 AM (Source: MedicineNet Skin General)
Source: MedicineNet Skin General - November 22, 2019 Category: Dermatology Source Type: news

Vitamin C and Thiamine for Sepsis and Septic Shock
Sepsis and septic shock are medical emergencies resulting in significant morbidity and mortality. Intravenous (IV) vitamin C, thiamine, and hydrocortisone have shown promise in reducing hospital mortality. The Memphis Veterans Affairs Medical Center (VAMC) similarly implemented this regimen, called the vitamin C protocol, for patients presenting in sepsis or septic shock in the intensive care unit (ICU). Although no significant mortality benefit was observed, the vitamin C protocol was not associated with patient harm. In this Veteran population, there was reduced ICU length of stay, suggesting possible benefit. Though fur...
Source: Current Awareness Service for Health (CASH) - September 19, 2019 Category: Consumer Health News Source Type: news

Vytone (Hydrocortisone Acetate, USP 1.9%, Iodoquinol, USP 1%) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 17, 2019 Category: Drugs & Pharmacology Source Type: news

Protopic Ointment vs. Hydrocortisone
Title: Protopic Ointment vs. HydrocortisoneCategory: MedicationsCreated: 8/12/2019 12:00:00 AMLast Editorial Review: 8/12/2019 12:00:00 AM (Source: MedicineNet Skin General)
Source: MedicineNet Skin General - August 12, 2019 Category: Dermatology Source Type: news

Lucky Mart Inc. Issues Voluntary Nationwide Recall Of Piyanping Anti-Itch Lotion Due to Incorrect Active Ingredient
Lucky Mart Inc. is voluntarily recalling lots C14005, C16001 and C16002 of Piyanping Anti-Itch Lotion to the consumer level. The product was manufactured using the active pharmaceutical ingredient dexamethasone rather than hydrocortisone. Dexamethasone is not listed as an ingredient in the labeling. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - July 24, 2019 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Impact of CBG Circadian Rhythm on Cortisol Exposure Impact of CBG Circadian Rhythm on Cortisol Exposure
How does the circadian rhythm of CBG impact cortisol exposure after hydrocortisone administration?Clinical Endocrinology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 17, 2019 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

How to treat wounds caused by insects and animal bites
  Being outdoors during the warm weather season carries with it the risk of bites of all kinds – insects, animals, ticks and others. Here is some helpful advice for treating bites and itching. Check the symptoms. Most insect bites and stings are mild, causing minor symptoms like itching, redness, stinging or a small degree of swelling around the bite. In some rare cases, stings from hornets, bees, wasps, scorpions or fire ants may lead to more serious reactions, including mosquito-borne West Nile virus. The Mayo Clinic advises moving away from the area where you were stung or bitten to prevent further injur...
Source: Advanced Tissue - June 10, 2019 Category: Dermatology Authors: AdvancedTissue Tags: Wound Care Wound care products wound care treatment Source Type: news

Traumatic imagery following glucocorticoid administration in earthquake-related post-traumatic stress disorder: a preliminary functional magnetic resonance imaging study - Douglas KM, Groves S, Porter RJ, Jordan J, Wilson L, Melzer TR, Wise RG, Bisson JI, Bell CJ.
OBJECTIVE: Post-traumatic stress disorder involves excessive retrieval of traumatic memories. Glucocorticoids impair declarative memory retrieval. This preliminary study examined the effect of acute hydrocortisone administration on brain activation in indi... (Source: SafetyLit)
Source: SafetyLit - June 4, 2019 Category: International Medicine & Public Health Tags: Disaster Preparedness Source Type: news

Vitamin C, Hydrocortisone, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Analysis of Real-World Application
A recent study suggested mortality benefits using vitamin C, hydrocortisone, and thiamine combination therapy (triple therapy) in addition to standard care in patients with severe sepsis and septic shock. In order to further evaluate the effects of triple therapy in real-world clinical practice, we conducted a retrospective observational cohort study at an academic tertiary care hospital. When compared to standard care, triple therapy did not improve hospital or ICU mortality in patients with septic shock. A randomized controlled trial evaluating the effects of triple therapy is necessary prior to implementing vitamin C, h...
Source: Current Awareness Service for Health (CASH) - May 29, 2019 Category: Consumer Health News Source Type: news

Essential wound care supplies for your home first aid kit
When the cut, scrape, blister or bleeding happens, you don't want to be stuck running in a panicked frenzy to the closest drug store. Instead, be prepared for common injuries, symptoms and ailments with a well-stocked medicine cabinet and home first aid kit. Here are the essential wound care supplies you should have on hand at home: Make sure your home first aid kit is well stocked. For cuts and scrapes: The basic must-haves for these minor wounds include: Adhesive bandages in various sizes. Sterile gauze pads. Medical tape. Antibiotic ointment. The size of the wound will help you determine whether a bandage will s...
Source: Advanced Tissue - April 29, 2019 Category: Dermatology Authors: AdvancedTissue Tags: Wound Care Wound care products Source Type: news

Hydrocortisone Tablets, USP (New - Discontinuation)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - April 19, 2019 Category: Drugs & Pharmacology Source Type: news

Hydrocortisone Does Not Reduce BPD in Preemies Hydrocortisone Does Not Reduce BPD in Preemies
Systemic hydrocortisone did not reduce the risk for a composite endpoint of death or bronchopulmonary dysplasia in very preterm infants receiving mechanical ventilation, a randomized trial found.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 30, 2019 Category: Consumer Health News Tags: Pediatrics News Source Type: news

Hydrocortisone, Ascorbic Acid and Thiamine (HAT Therapy) for the Treatment of Sepsis. Focus on Ascorbic Acid
The authors of this journal article state that sepsis is a devastating disease that carries an enormous toll in terms of human suffering and lives lost. They say that over 100 novel pharmacologic agents that targeted specific molecules or pathways have failed to improve the outcome of sepsis. Preliminary data suggests that the combination of Hydrocortisone, Ascorbic Acid and Thiamine (HAT therapy) may reduce organ failure and mortality in patients with sepsis and septic shock. HAT therapy is based on the concept that a combination of readily available, safe and cheap agents, which target multiple components of the host's r...
Source: Current Awareness Service for Health (CASH) - December 28, 2018 Category: Consumer Health News Source Type: news

Hydrocortisone muco-adhesive buccal tablets
should not be used off-label for treating adrenal insufficiency in children due to serious risks. There is a risk of insufficient cortisol absorption and li (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - December 19, 2018 Category: Drugs & Pharmacology Source Type: news

MiCort HC (Hydrocortisone Acetate Cream) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 19, 2018 Category: Drugs & Pharmacology Source Type: news

hydrocortisone oral (Cortef)
Title: hydrocortisone oral (Cortef)Category: MedicationsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 12/17/2018 12:00:00 AM (Source: MedicineNet Asthma General)
Source: MedicineNet Asthma General - December 17, 2018 Category: Respiratory Medicine Source Type: news

hydrocortisone valerate
Title: hydrocortisone valerateCategory: MedicationsCreated: 4/4/1999 12:00:00 AMLast Editorial Review: 12/10/2018 12:00:00 AM (Source: MedicineNet Skin General)
Source: MedicineNet Skin General - December 10, 2018 Category: Dermatology Source Type: news

Ascorbic acid, corticosteroids, and thiamine in sepsis: a review of the biologic rationale and the present state of clinical evaluation
This review states that the combination of thiamine, ascorbic acid, and hydrocortisone has recently emerged as a potential adjunctive therapy to antibiotics, infectious source control, and supportive care for patients with sepsis and septic shock. In the present manuscript, the authors provide a comprehensive review of the pathophysiologic basis and supporting research for each element of the thiamine, ascorbic acid, and hydrocortisone drug combination in sepsis. In addition, they describe potential areas of synergy between these therapies and discuss the strengths/weaknesses of the two studies to date which have evaluated...
Source: Current Awareness Service for Health (CASH) - November 16, 2018 Category: Consumer Health News Source Type: news

Our daughter ’s eczema was out of control until we found Dr Aron
Life was like Groundhog Day for our family but then a South African dermatologist and his regimen improved things considerablyFucibet, Clobevate, hydrocortisone creams and gels, Daktacort, Epaderm, Elocon, E45, Dermol, Eumovate, calamine lotion, Pinetarsol solution, antihistamines, Piriton, Ucerax, wet wraps, dry wraps, cradle cap shampoo, all kinds of moisturisers, topical steroids, topical antibiotics, Prednisolone oral steroid, Elidel … GPs, dermatologists and consultants all offered their own variation on this list. Chekhov said, “When many solutions are offered, it means the problem is unsolvable,” ...
Source: Guardian Unlimited Science - August 5, 2018 Category: Science Authors: Chris Hall Tags: Eczema Parents and parenting Family Life and style Health & wellbeing Source Type: news

The role of glucocorticoids as adjunctive treatment for sepsis in the modern era
This viewpoint critically appraises two large RCTs published this year investigating the role of hydrocortisone n patients with septic shock, which had conflicting results. It evaluates the use of glucocorticoids in the treatment of sepsis and septic shock in the modern era. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - July 12, 2018 Category: Consumer Health News Source Type: news

9 Kinds of Bug Bites You Might Get This Summer — and What to Do About Them
This article originally appeared on Health.com (Source: TIME: Health)
Source: TIME: Health - June 4, 2018 Category: Consumer Health News Authors: Amanda Gardner / Health Tags: Uncategorized healthytime onetime public health Source Type: news

Myths in Emergency Medicine: Inconsistencies in Hydrocortisone Trial for Septic Shock Make Findings Suspect
No abstract available (Source: Emergency Medicine News)
Source: Emergency Medicine News - May 1, 2018 Category: Emergency Medicine Tags: Myths in Emergency Medicine Source Type: news

Hydrocortisone Granules Specially Formulated for Children Hydrocortisone Granules Specially Formulated for Children
New data suggest that the pediatric hydrocortisone formulation Infacort is equivalently absorbed whether taken directly by mouth or sprinkled on soft food.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 21, 2018 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Hydrocortisone Granules on Par, Given Straight or With Food
(MedPage Today) -- May be helpful option for administering meds to pediatric patients, researcher says (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - March 19, 2018 Category: Endocrinology Source Type: news

Hydrocortisone plus Fludrocortisone for Adults with Septic Shock
This research article reported 90-day all-cause mortality was lower in hydrocortisone plus fludrocortisone vs. placebo group. The rate of serious adverse events did not differ significantly, but hyperglycaemia was more common in steroid group. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - March 7, 2018 Category: Consumer Health News Source Type: news

Adjunctive Glucocorticoid Therapy in Patients with Septic Shock
This research article outlines a study of patients with septic shock undergoing mechanical ventilation. It found that a continuous infusion of hydrocortisone (200mg daily) did not reduce 90-day mortality (27.9% v 28.8% with placebo; OR 0.95; 95% CI 0.82 to 1.10; P=0.50). (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - January 25, 2018 Category: Consumer Health News Source Type: news

Steroids Speed Recovery From Septic Shock; No Survival Benefit Steroids Speed Recovery From Septic Shock; No Survival Benefit
A hydrocortisone infusion does not reduce mortality among septic shock patients undergoing mechanical ventilation, but it does speed recovery when the condition is not fatal, according to an international study of 3,658 patients treated over four years.Reuters Health Information (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - January 23, 2018 Category: Intensive Care Tags: Critical Care News Source Type: news

Study Supports Early Postnatal Steroids for Extremely Preterm Infants Study Supports Early Postnatal Steroids for Extremely Preterm Infants
New data confirm the value of early low-dose prophylactic hydrocortisone in extremely preterm infants and suggest that those born after placental vascular disease may benefit the most.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 19, 2018 Category: Consumer Health News Tags: Medscape Today News Source Type: news

Hydrocortisone Does Not Seem to Reduce Mortality in Certain Patients with Septic Shock
Hydrocortisone is not associated with reduced mortality in patients with septic shock who undergo mechanical ventilation, according to a study published in the New England... (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - January 19, 2018 Category: Primary Care Source Type: news

Researchers develop first cortisol treatment specifically designed for infants
EU-funded researchers have developed a treatment tailored for babies and children lacking the stress hormone cortisol. The drug, the first hydrocortisone formulation specifically designed for infants, could become available next year following successful clinical trials. (Source: EUROPA - Research Information Centre)
Source: EUROPA - Research Information Centre - January 18, 2018 Category: Research Source Type: news

Once a day glucocorticoid therapy improves health in adrenal insufficiency
According to an Italian study, published in theLancet Diabetes& Endocrinology, adrenal insufficiency patients treated once a day with hydrocortisone have improved immune and metabolic function compared with those on conventional therapy.Healio (Source: Society for Endocrinology)
Source: Society for Endocrinology - December 15, 2017 Category: Endocrinology Source Type: news

Department of Health advice on hydrocortisone sodium phosphate shortage
There is currently a shortage of hydrocortisone sodium phosphate 100 mg injection (formerly branded as Efcortesol injection). The sole licensed UK supplier, Concordia, does not expect to be able to supply this product again until late in 2018.The Department of Health (DOH) have commissioned some clinical advice on this matter and Solu-Cortef (hydrocortisone sodium succinate) 100 mg, manufactured by Pfizer, is considered an acceptable alternative during this time.Due to differences in formulation and administration the DOH have also commissioned thisguidance on the use of Solu-Cortef.These videos demonstrate the pr...
Source: Society for Endocrinology - December 8, 2017 Category: Endocrinology Source Type: news

Prednisone vs. Hydrocortisone
Title: Prednisone vs. HydrocortisoneCategory: MedicationsCreated: 10/31/2017 12:00:00 AMLast Editorial Review: 10/31/2017 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - October 31, 2017 Category: Drugs & Pharmacology Source Type: news

Lucky Mart Inc. Issues Voluntary Nationwide Recall Of Piyanping Anti-Itch Lotion Due to Incorrect Active Ingredient
Lucky Mart Inc. is voluntarily recalling lots C14005, C16001 and C16002 of Piyanping Anti-Itch Lotion to the consumer level. The product was manufactured using the active pharmaceutical ingredient dexamethasone rather than hydrocortisone. Dexamethasone is not listed as an ingredient in the labeling. (Source: Food and Drug Administration)
Source: Food and Drug Administration - August 30, 2017 Category: Food Science Source Type: news

Your NEJM Group Today: Salt-and-Pepper Skin Changes / Vitamin C, Thiamine, & Hydrocortisone for Sepsis / Ohio IM Opportunities (FREE)
By the Editors Have a look at some of the latest clinical content from NEJM Group:NEJM Clinical Practice Center: Images in clinical medicine: A … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - July 19, 2017 Category: Primary Care Source Type: news

Cortaid (Hydrocortisone Cream and Ointment 1.0%) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - June 28, 2017 Category: Drugs & Pharmacology Source Type: news

Cortisporin Ointment (Neomycin and Polymyxin B Sulfates, Bacitracin Zinc, and Hydrocortisone) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - June 21, 2017 Category: Drugs & Pharmacology Source Type: news

Coly-Mycin S Otic (Colistin Sulfate with Neomycin and Hydrocortisone ) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - June 16, 2017 Category: Drugs & Pharmacology Source Type: news

Analpram HC (Hydrocortisone Acetate 2.5% Pramoxine HCl 1%) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - June 5, 2017 Category: Drugs & Pharmacology Source Type: news

Is It A Poison Ivy Rash? How To Tell — And How To Treat It
By Jessica Migala You’ve probably feared a run-in with poison ivy since you were a kid. Even brushing up against the pointy leaves is risky, says Temitayo A. Ogunleye, MD, assistant professor of dermatology at the Perelman School of Medicine at the University of Pennsylvania. The climbing plant contains an irritating resin, called urushiol, that can transfer to your skin via touch, she explains. You might also be exposed to the oily liquid by a pet who picks up the resin on his fur and then passes it along to you. You can even inhale urushiol if, say, you mow over a large patch of poison ivy in your yard,&n...
Source: Healthy Living - The Huffington Post - May 31, 2017 Category: Consumer Health News Source Type: news

How Much Peanut Butter Should He Take?
Discussion Peanut allergy is an increasing problem with ~2% prevalence in the United States. It is also the leading cause of food-related death. The LEAP trial (Learning Early about Peanut Allergy trial) was a randomized trial of early introduction of peanut foods to try to prevent peanut allergy. It found a significant decrease in peanut allergy at 60 months of age with early introduction of peanut foods to infants. This finding occurred in participants with baseline negative skin testing (13.7% in peanut avoidance group versus 1.9% in peanut consumption group) or those with measureable peanut skin testing at study entry ...
Source: PediatricEducation.org - May 22, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news