Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19 A Meta-analysis
Importance Effective therapies for patients with coronavirus disease 2019 (COVID-19) are needed, and clinical trial data have demonstrated that low-dose dexamethasone reduced mortality in hospitalized patients with COVID-19 who required respiratory support. Objective To estimate the association between administration of corticosteroids compared with usual care or placebo and 28-day all-cause mortality. Design, Setting, and Participants Prospective meta-analysis that pooled data from 7 randomized clinical trials that evaluated the efficacy of corticosteroids in 1703 critically ill patients with COVID-19. The trials were con...
Source: Current Awareness Service for Health (CASH) - September 17, 2020 Category: Consumer Health News Source Type: news

Hydrocortisone Early After Septic Shock Onset May Aid Outcomes
THURSDAY, Sept. 17, 2020 -- For patients with vasopressor-dependent septic shock, early hydrocortisone use is associated with improved outcomes, according to a study published online Sept. 2 in SHOCK. Gretchen L. Sacha, Pharm.D., from the Cleveland... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - September 17, 2020 Category: Pharmaceuticals Source Type: news

Prevention of Adrenal Crisis Prevention of Adrenal Crisis
What is the most appropriate hydrocortisone dose and delivery mode to prevent adrenal crisis among patients with adrenal insufficiency?Journal of Clinical Endocrinology & Metabolism (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 17, 2020 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Study says cheap steroid reduces COVID-19 mortality by 33%
(Natural News) Some interesting news has emerged about a possible remedy for the Wuhan coronavirus (COVID-19) that, just like hydroxychloroquine (HCQ), is inexpensive and already widely available. A study published in the Journal of the American Medical Association found that the commonly used steroid drugs dexamethasone, hydrocortisone and methylprednisolone can help to reduce the mortality... (Source: NaturalNews.com)
Source: NaturalNews.com - September 6, 2020 Category: Consumer Health News Source Type: news

Corticosteroids in the treatment of suspected or confirmed COVID-19 , Chief Medical Officer
Following recent publication of the REMAP-CAP trial for hydrocortisone and a meta-analysis of corticosteroids, the WHO has recently issued new interim guidance recommending the use of systemic corticosteroids in severe and critical COVID-19 disease. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 4, 2020 Category: Consumer Health News Source Type: news

Widely-used and cheap steroid hydrocortisone can cut coronavirus deaths by a THIRD
An analysis by University of Bristol of seven different studies found three steroids reduce the risk of death in critically ill Covid-19 patients by 20%, which bumped up to 31% for hydrocortisone. (Source: the Mail online | Health)
Source: the Mail online | Health - September 3, 2020 Category: Consumer Health News Source Type: news

Two types of steroid found to save lives of some Covid-19 patients
Analysis of seven trials finds dexamethasone and hydrocortisone should be given in severe casesCoronavirus – latest updatesSee all our coronavirus coverageStudies around the world have confirmed that steroids can save lives in the Covid-19 pandemic, leading to new recommendations from the World Heath Organization that doctors should give them to severely ill patients.In June, the Recovery trial run in most NHS hospitals and led by Oxford University found that the lives of one in eight people sick enough from Covid-19 to need a ventilator could be saved by a steroid called dexamethasone.Continue reading... (Source: Gu...
Source: Guardian Unlimited Science - September 3, 2020 Category: Science Authors: Sarah Boseley Health editor Tags: Medical research Coronavirus outbreak Science World news Source Type: news

Inexpensive Steroids Can Save Lives Of Seriously Ill COVID-19 Patients
Multiple studies now confirm earlier research: Dexamethasone and hydrocortisone, drugs that reduce an immune system's overreaction, can help reduce deaths of hospitalized COVID-19 patients.(Image credit: Photo Illustration by Soumyabrata Roy/NurPhoto via Getty Images) (Source: NPR Health and Science)
Source: NPR Health and Science - September 2, 2020 Category: Consumer Health News Authors: Richard Harris Source Type: news

Coronavirus treatment breakthrough: Cheap hydrocortisone steroid drastically cuts deaths
CORONAVIRUS update: The fight against coronavirus has been strengthened after studies have found hydrocortisone, an anti-inflammatory drug, drastically reduced mortality rate in the sickest patients. In light of the findings, the NHS plans to roll out the drug immediately. (Source: Daily Express - Health)
Source: Daily Express - Health - September 2, 2020 Category: Consumer Health News Source Type: news

WHO recommends cheap everyday steroids as Covid-19 treatment
Dexamethasone and hydrocortisone offer hope in curbing death toll (Source: FT.com - Drugs and Healthcare)
Source: FT.com - Drugs and Healthcare - September 2, 2020 Category: Pharmaceuticals Source Type: news

Steroid found to improve survival of critically ill COVID-19 patients
A new international study published today has shown that treating critically ill patients with COVID-19 with the steroid hydrocortisone improves their chances of recovery. The study, led in the UK by Professor Anthony Gordon from Imperial College London with collaborators from the Intensive Care National Audit & Research Centre, found that patients receiving intensive care who were treated with a regular fixed dose of the steroid hydrocortisone for seven days had a better chance of recovery, compared with the patients who were not treated with the steroid. (Source: World Pharma News)
Source: World Pharma News - September 2, 2020 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Steroid found to improve survival of critically ill COVID-19 patients
(Imperial College London) A new international study published today [02 September] has shown that treating critically ill patients with COVID-19 with the steroid hydrocortisone improves their chances of recovery. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - September 2, 2020 Category: Infectious Diseases Source Type: news

Effect of hydrocortisone on death, organ support in patients with severe COVID-19
(JAMA Network) This randomized clinical trial of patients with severe COVID-19 was stopped early after results from   another trial were released but this study investigated whether   intravenous hydrocortisone (administered either as a seven-day fixed-dose course or restricted to when shock is clinically evident) improved 21-day organ support-free days. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - September 2, 2020 Category: Infectious Diseases Source Type: news

Effect of hydrocortisone on death, respiratory support among critically ill COVID-19 patients
(JAMA Network) The purpose of this randomized clinical trial in France   was to evaluate the effect of low-dose hydrocortisone for the treatment of ICU patients with COVID-19-related acute respiratory failure but the trial was stopped early. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - September 2, 2020 Category: Infectious Diseases Source Type: news

Colocort (Hydrocortisone Rectal Suspension) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - April 23, 2020 Category: Drugs & Pharmacology Source Type: news

Treating sepsis with vitamin C, thiamine, and hydrocortisone: Exploring the quest for the magic elixir
The administration of ascorbic acid (vitamin C) alone or in combination with thiamine (vitamin B1) and corticosteroids (VCTS) has recently been hypothesized to improve hemodynamics, end-organ function, and may even increase survival in critically ill patients. This review aims to explore the current evidence and potential benefits and adverse effects of the VCTS regimen for the treatment of sepsis. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - March 26, 2020 Category: Consumer Health News Source Type: news

Effects of hydrocortisone and yohimbine on decision-making under risk - Metz S, Waiblinger-Grigull T, Schulreich S, Chae WR, Otte C, Heekeren HR, Wingenfeld K.
INTRODUCTION: Many studies have investigated the influence of stress on decision-making. However, results are equivocal and the exact role of increased noradrenaline and cortisol after stress remains unclear. Using pharmacological manipulation, we investig... (Source: SafetyLit)
Source: SafetyLit - February 11, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Effect of Vitamin C, Hydrocortisone, and Thiamine vs Hydrocortisone Alone on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock: The VITAMINS Randomized Clinical Trial
RCT (n=216) found that treatment with intravenous vitamin C, hydrocortisone, and thiamine, compared with intravenous hydrocortisone alone, did not significantly improve the duration of time alive and free of vasopressor administration over 7 days. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - February 6, 2020 Category: Consumer Health News Source Type: news

High-Dose IV Vitamin C Does Not Speed Resolution of Septic Shock
FRIDAY, Jan. 24, 2020 -- Treatment with intravenous vitamin C, hydrocortisone, and thiamine does not improve the duration of time alive and vasopressor administration-free compared with intravenous hydrocortisone alone among patients with septic... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 24, 2020 Category: Pharmaceuticals Source Type: news

Vitamin Cocktail for Sepsis Fails; PPI for Stress Ulcer Prevention May Be Risky: ICU Studies Vitamin Cocktail for Sepsis Fails; PPI for Stress Ulcer Prevention May Be Risky: ICU Studies
A major new study of intensive care unit (ICU) patients with septic shock failed to find a benefit of giving an intravenous cocktail of vitamin C, hydrocortisone and thiamine, relative to hydrocortisone alone.Reuters Health Information (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - January 22, 2020 Category: Intensive Care Tags: Critical Care News Source Type: news

Vitamin C-B1-steroid combo linked to lower septic shock mortality in kids
(Ann& Robert H. Lurie Children's Hospital of Chicago) Treating septic shock in children with a combination of intravenous vitamin C, vitamin B1 and hydrocortisone (a commonly used steroid) is associated with lower mortality, according to a study from Ann& Robert H. Lurie Children's Hospital of Chicago. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 21, 2020 Category: International Medicine & Public Health Source Type: news

VITAMINS trial report on vitamin C, hydrocortisone, thiamine for septic shock
(JAMA Network) In this   randomized clinical trial of about 200 patients with septic shock, combination treatment with intravenous vitamin C, hydrocortisone and thiamine compared with intravenous hydrocortisone alone didn't significantly improve the amount of time patients were alive and free of medicines that raise blood pressure (vasopressors) over seven days. The study findings are being released to coincide with presentation at the Critical Care Reviews Meeting 2020 in Belfast, Northern Ireland. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 17, 2020 Category: International Medicine & Public Health Source Type: news

pramoxine and hydrocortisone (Epifoam, Pramosone, Proctofoam HC, Procort, Analpram HC)
Title: pramoxine and hydrocortisone (Epifoam, Pramosone, Proctofoam HC, Procort, Analpram HC)Category: MedicationsCreated: 3/2/2005 12:00:00 AMLast Editorial Review: 11/22/2019 12:00:00 AM (Source: MedicineNet Skin General)
Source: MedicineNet Skin General - November 22, 2019 Category: Dermatology Source Type: news

Vitamin C and Thiamine for Sepsis and Septic Shock
Sepsis and septic shock are medical emergencies resulting in significant morbidity and mortality. Intravenous (IV) vitamin C, thiamine, and hydrocortisone have shown promise in reducing hospital mortality. The Memphis Veterans Affairs Medical Center (VAMC) similarly implemented this regimen, called the vitamin C protocol, for patients presenting in sepsis or septic shock in the intensive care unit (ICU). Although no significant mortality benefit was observed, the vitamin C protocol was not associated with patient harm. In this Veteran population, there was reduced ICU length of stay, suggesting possible benefit. Though fur...
Source: Current Awareness Service for Health (CASH) - September 19, 2019 Category: Consumer Health News Source Type: news

Vytone (Hydrocortisone Acetate, USP 1.9%, Iodoquinol, USP 1%) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 17, 2019 Category: Drugs & Pharmacology Source Type: news

Protopic Ointment vs. Hydrocortisone
Title: Protopic Ointment vs. HydrocortisoneCategory: MedicationsCreated: 8/12/2019 12:00:00 AMLast Editorial Review: 8/12/2019 12:00:00 AM (Source: MedicineNet Skin General)
Source: MedicineNet Skin General - August 12, 2019 Category: Dermatology Source Type: news

Lucky Mart Inc. Issues Voluntary Nationwide Recall Of Piyanping Anti-Itch Lotion Due to Incorrect Active Ingredient
Lucky Mart Inc. is voluntarily recalling lots C14005, C16001 and C16002 of Piyanping Anti-Itch Lotion to the consumer level. The product was manufactured using the active pharmaceutical ingredient dexamethasone rather than hydrocortisone. Dexamethasone is not listed as an ingredient in the labeling. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - July 24, 2019 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Impact of CBG Circadian Rhythm on Cortisol Exposure Impact of CBG Circadian Rhythm on Cortisol Exposure
How does the circadian rhythm of CBG impact cortisol exposure after hydrocortisone administration?Clinical Endocrinology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 17, 2019 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

How to treat wounds caused by insects and animal bites
  Being outdoors during the warm weather season carries with it the risk of bites of all kinds – insects, animals, ticks and others. Here is some helpful advice for treating bites and itching. Check the symptoms. Most insect bites and stings are mild, causing minor symptoms like itching, redness, stinging or a small degree of swelling around the bite. In some rare cases, stings from hornets, bees, wasps, scorpions or fire ants may lead to more serious reactions, including mosquito-borne West Nile virus. The Mayo Clinic advises moving away from the area where you were stung or bitten to prevent further injur...
Source: Advanced Tissue - June 10, 2019 Category: Dermatology Authors: AdvancedTissue Tags: Wound Care Wound care products wound care treatment Source Type: news

Traumatic imagery following glucocorticoid administration in earthquake-related post-traumatic stress disorder: a preliminary functional magnetic resonance imaging study - Douglas KM, Groves S, Porter RJ, Jordan J, Wilson L, Melzer TR, Wise RG, Bisson JI, Bell CJ.
OBJECTIVE: Post-traumatic stress disorder involves excessive retrieval of traumatic memories. Glucocorticoids impair declarative memory retrieval. This preliminary study examined the effect of acute hydrocortisone administration on brain activation in indi... (Source: SafetyLit)
Source: SafetyLit - June 4, 2019 Category: International Medicine & Public Health Tags: Disaster Preparedness Source Type: news

Vitamin C, Hydrocortisone, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Analysis of Real-World Application
A recent study suggested mortality benefits using vitamin C, hydrocortisone, and thiamine combination therapy (triple therapy) in addition to standard care in patients with severe sepsis and septic shock. In order to further evaluate the effects of triple therapy in real-world clinical practice, we conducted a retrospective observational cohort study at an academic tertiary care hospital. When compared to standard care, triple therapy did not improve hospital or ICU mortality in patients with septic shock. A randomized controlled trial evaluating the effects of triple therapy is necessary prior to implementing vitamin C, h...
Source: Current Awareness Service for Health (CASH) - May 29, 2019 Category: Consumer Health News Source Type: news

Essential wound care supplies for your home first aid kit
When the cut, scrape, blister or bleeding happens, you don't want to be stuck running in a panicked frenzy to the closest drug store. Instead, be prepared for common injuries, symptoms and ailments with a well-stocked medicine cabinet and home first aid kit. Here are the essential wound care supplies you should have on hand at home: Make sure your home first aid kit is well stocked. For cuts and scrapes: The basic must-haves for these minor wounds include: Adhesive bandages in various sizes. Sterile gauze pads. Medical tape. Antibiotic ointment. The size of the wound will help you determine whether a bandage will s...
Source: Advanced Tissue - April 29, 2019 Category: Dermatology Authors: AdvancedTissue Tags: Wound Care Wound care products Source Type: news

Hydrocortisone Tablets, USP (New - Discontinuation)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - April 19, 2019 Category: Drugs & Pharmacology Source Type: news

Hydrocortisone Does Not Reduce BPD in Preemies Hydrocortisone Does Not Reduce BPD in Preemies
Systemic hydrocortisone did not reduce the risk for a composite endpoint of death or bronchopulmonary dysplasia in very preterm infants receiving mechanical ventilation, a randomized trial found.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 30, 2019 Category: Consumer Health News Tags: Pediatrics News Source Type: news

Hydrocortisone, Ascorbic Acid and Thiamine (HAT Therapy) for the Treatment of Sepsis. Focus on Ascorbic Acid
The authors of this journal article state that sepsis is a devastating disease that carries an enormous toll in terms of human suffering and lives lost. They say that over 100 novel pharmacologic agents that targeted specific molecules or pathways have failed to improve the outcome of sepsis. Preliminary data suggests that the combination of Hydrocortisone, Ascorbic Acid and Thiamine (HAT therapy) may reduce organ failure and mortality in patients with sepsis and septic shock. HAT therapy is based on the concept that a combination of readily available, safe and cheap agents, which target multiple components of the host's r...
Source: Current Awareness Service for Health (CASH) - December 28, 2018 Category: Consumer Health News Source Type: news

Hydrocortisone muco-adhesive buccal tablets
should not be used off-label for treating adrenal insufficiency in children due to serious risks. There is a risk of insufficient cortisol absorption and li (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - December 19, 2018 Category: Drugs & Pharmacology Source Type: news

MiCort HC (Hydrocortisone Acetate Cream) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 19, 2018 Category: Drugs & Pharmacology Source Type: news

hydrocortisone oral (Cortef)
Title: hydrocortisone oral (Cortef)Category: MedicationsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 12/17/2018 12:00:00 AM (Source: MedicineNet Asthma General)
Source: MedicineNet Asthma General - December 17, 2018 Category: Respiratory Medicine Source Type: news

hydrocortisone valerate
Title: hydrocortisone valerateCategory: MedicationsCreated: 4/4/1999 12:00:00 AMLast Editorial Review: 12/10/2018 12:00:00 AM (Source: MedicineNet Skin General)
Source: MedicineNet Skin General - December 10, 2018 Category: Dermatology Source Type: news

Ascorbic acid, corticosteroids, and thiamine in sepsis: a review of the biologic rationale and the present state of clinical evaluation
This review states that the combination of thiamine, ascorbic acid, and hydrocortisone has recently emerged as a potential adjunctive therapy to antibiotics, infectious source control, and supportive care for patients with sepsis and septic shock. In the present manuscript, the authors provide a comprehensive review of the pathophysiologic basis and supporting research for each element of the thiamine, ascorbic acid, and hydrocortisone drug combination in sepsis. In addition, they describe potential areas of synergy between these therapies and discuss the strengths/weaknesses of the two studies to date which have evaluated...
Source: Current Awareness Service for Health (CASH) - November 16, 2018 Category: Consumer Health News Source Type: news

Our daughter ’s eczema was out of control until we found Dr Aron
Life was like Groundhog Day for our family but then a South African dermatologist and his regimen improved things considerablyFucibet, Clobevate, hydrocortisone creams and gels, Daktacort, Epaderm, Elocon, E45, Dermol, Eumovate, calamine lotion, Pinetarsol solution, antihistamines, Piriton, Ucerax, wet wraps, dry wraps, cradle cap shampoo, all kinds of moisturisers, topical steroids, topical antibiotics, Prednisolone oral steroid, Elidel … GPs, dermatologists and consultants all offered their own variation on this list. Chekhov said, “When many solutions are offered, it means the problem is unsolvable,” ...
Source: Guardian Unlimited Science - August 5, 2018 Category: Science Authors: Chris Hall Tags: Eczema Parents and parenting Family Life and style Health & wellbeing Source Type: news

The role of glucocorticoids as adjunctive treatment for sepsis in the modern era
This viewpoint critically appraises two large RCTs published this year investigating the role of hydrocortisone n patients with septic shock, which had conflicting results. It evaluates the use of glucocorticoids in the treatment of sepsis and septic shock in the modern era. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - July 12, 2018 Category: Consumer Health News Source Type: news

9 Kinds of Bug Bites You Might Get This Summer — and What to Do About Them
This article originally appeared on Health.com (Source: TIME: Health)
Source: TIME: Health - June 4, 2018 Category: Consumer Health News Authors: Amanda Gardner / Health Tags: Uncategorized healthytime onetime public health Source Type: news

Myths in Emergency Medicine: Inconsistencies in Hydrocortisone Trial for Septic Shock Make Findings Suspect
No abstract available (Source: Emergency Medicine News)
Source: Emergency Medicine News - May 1, 2018 Category: Emergency Medicine Tags: Myths in Emergency Medicine Source Type: news

Hydrocortisone Granules Specially Formulated for Children Hydrocortisone Granules Specially Formulated for Children
New data suggest that the pediatric hydrocortisone formulation Infacort is equivalently absorbed whether taken directly by mouth or sprinkled on soft food.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 21, 2018 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Hydrocortisone Granules on Par, Given Straight or With Food
(MedPage Today) -- May be helpful option for administering meds to pediatric patients, researcher says (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - March 19, 2018 Category: Endocrinology Source Type: news