Vitamin C alleviates rheumatoid arthritis by modulating gut microbiota balance
In conclusion, our results demonstrate the potential of vitamin C as a potential therapeutic choice for RA.PMID:38599880 | DOI:10.5582/bst.2024.01037 (Source: BioScience Trends)
Source: BioScience Trends - April 10, 2024 Category: Biomedical Science Authors: Yanjie Zhang Sibin Zhen Hao Xu Songfang Sun Ziwei Wang Mian Li Liang Zou Yangyang Zhang Yan Zhao Yazhou Cui Jinxiang Han Source Type: research
Roles and mechanisms of copper homeostasis and cuproptosis in osteoarticular diseases
Biomed Pharmacother. 2024 Apr 9;174:116570. doi: 10.1016/j.biopha.2024.116570. Online ahead of print.ABSTRACTCopper is an essential trace element in the human body that is extensively distributed throughout various tissues. The appropriate level of copper is crucial to maintaining the life activities of the human body, and the excess and deficiency of copper can lead to various diseases. The copper levels in the human body are regulated by copper homeostasis, which maintains appropriate levels of copper in tissues and cells by controlling its absorption, transport, and storage. Cuproptosis is a distinct form of cell death ...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - April 10, 2024 Category: Drugs & Pharmacology Authors: Juanjuan Han Jiayi Luo Cuijing Wang Leonid Kapilevich Xin-An Zhang Source Type: research
Understanding preferences for receiving health communications and information about clinical trials: a cross-sectional study among US adults
CONCLUSION: Effective health communication may be achieved via multiple formats shared directly by healthcare providers.PMID:38595182 | DOI:10.1080/03007995.2024.2340720 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - April 10, 2024 Category: Research Authors: Dalia Majumdar Diane Webb Stephanie Parsons Elizabeth M Selwan-Lewis Trisha Rettig Emily Chastain Winifred Obanor Rob Birnberg Amy Kuang Source Type: research
Vitamin C alleviates rheumatoid arthritis by modulating gut microbiota balance
In conclusion, our results demonstrate the potential of vitamin C as a potential therapeutic choice for RA.PMID:38599880 | DOI:10.5582/bst.2024.01037 (Source: BioScience Trends)
Source: BioScience Trends - April 10, 2024 Category: Biomedical Science Authors: Yanjie Zhang Sibin Zhen Hao Xu Songfang Sun Ziwei Wang Mian Li Liang Zou Yangyang Zhang Yan Zhao Yazhou Cui Jinxiang Han Source Type: research
Clinical Outcomes of Total Wrist Arthroplasty in Patients With Rheumatoid Arthritis: Minimum 10-Year Follow-Up Study
CONCLUSIONS: Total wrist arthroplasty using the semiconstrained arthroplasty system achieves favorable clinical outcomes with no serious complications requiring revision for 10 years after surgery.TYPE OF STUDY/LEVEL OF EVIDENCE: Therapeutic IV.PMID:38597835 | DOI:10.1016/j.jhsa.2024.03.002 (Source: Hand Surgery)
Source: Hand Surgery - April 10, 2024 Category: Surgery Authors: Yuichiro Matsui Akio Minami Makoto Kondo Jyunichi Ishikawa Makoto Motomiya Daisuke Kawamura Norimasa Iwasaki Source Type: research
Roles and mechanisms of copper homeostasis and cuproptosis in osteoarticular diseases
Biomed Pharmacother. 2024 Apr 9;174:116570. doi: 10.1016/j.biopha.2024.116570. Online ahead of print.ABSTRACTCopper is an essential trace element in the human body that is extensively distributed throughout various tissues. The appropriate level of copper is crucial to maintaining the life activities of the human body, and the excess and deficiency of copper can lead to various diseases. The copper levels in the human body are regulated by copper homeostasis, which maintains appropriate levels of copper in tissues and cells by controlling its absorption, transport, and storage. Cuproptosis is a distinct form of cell death ...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - April 10, 2024 Category: Drugs & Pharmacology Authors: Juanjuan Han Jiayi Luo Cuijing Wang Leonid Kapilevich Xin-An Zhang Source Type: research
Understanding preferences for receiving health communications and information about clinical trials: a cross-sectional study among US adults
CONCLUSION: Effective health communication may be achieved via multiple formats shared directly by healthcare providers.PMID:38595182 | DOI:10.1080/03007995.2024.2340720 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - April 10, 2024 Category: Research Authors: Dalia Majumdar Diane Webb Stephanie Parsons Elizabeth M Selwan-Lewis Trisha Rettig Emily Chastain Winifred Obanor Rob Birnberg Amy Kuang Source Type: research
Antinuclear antibodies may predict the development of immune-related adverse events in asymptomatic patients treated with immune checkpoint inhibitors: results from a single-center cohort
This study underlines the potential role of ANA positivity as a predictive biomarker for the development of irAEs. (Source: Clinical and Experimental Medicine)
Source: Clinical and Experimental Medicine - April 10, 2024 Category: Research Source Type: research
Latent class analysis of psychological resilience and influencing factors in patients with rheumatoid arthritis: a cross-sectional survey
ConclusionThree classes of RA patients ’ psychological resilience were identified by this study, and these classes were strongly correlated with individual treatment components. It is crucial to take into account the psychological resiliency of female RA patients who do not have a job. In order to improve psychological resilience, heal thcare staff should first increase their comprehension of treat-to-target. Furthermore, people with RA may become more psychologically resilient if they receive more social support.Key Points•Preliminary research found that psychological resilience in RA patients was associated with thre...
Source: Clinical Rheumatology - April 10, 2024 Category: Rheumatology Source Type: research
Joint-specific memory, resident memory T cells and the rolling window of opportunity in arthritis
Nature Reviews Rheumatology, Published online: 10 April 2024; doi:10.1038/s41584-024-01107-7This Review discusses joint-specific memory (the tendency of arthritis to recur in previously inflamed joints), explores the involvement of resident memory T cells and other contributors, and evaluates how arthritis might spread to new joints, emphasizing the important of sustained treatment. (Source: Nature Reviews Rheumatology)
Source: Nature Reviews Rheumatology - April 10, 2024 Category: Rheumatology Authors: Margaret H. Chang Robert C. Fuhlbrigge Peter A. Nigrovic Source Type: research
Anxiety and depression symptoms in adolescents and young adults with juvenile idiopathic arthritis: results of an outpatient screening
Previous studies have shown that growing up with rheumatic conditions can fuel dissatisfaction and psychological distress, which in turn affects disease self-management and treatment adherence. Primary objecti... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - April 10, 2024 Category: Rheumatology Authors: Florian Milatz, Jens Klotsche, Martina Niewerth, Claudia Sengler, Daniel Windschall, Tilmann Kallinich, Frank Dressler, Ralf Trauzeddel, Reinhard W. Holl, Ivan Foeldvari, Normi Br ück, Svenja Temming, Toni Hospach, Petra Warschburger, Rainer Berendes, Ga Tags: Research Source Type: research
Usability and preliminary effectiveness of an app-based physical activity and education program for people with hip or knee osteoarthritis – a pilot randomized controlled trial
Hip and knee osteoarthritis (OA) are highly prevalent worldwide. The guidelines recommend physical activity and education as the core treatments for osteoarthritis. Digital health has the potential to engage p... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - April 10, 2024 Category: Rheumatology Authors: F. Weber, C. Kloek, S. Stuhrmann, Y. Blum, C. Gr üneberg and C. Veenhof Tags: Research Source Type: research
Correction: Nintedanib downregulates the profibrotic M2 phenotype in cultured monocyte-derived macrophages obtained from systemic sclerosis patients affected by interstitial lung disease
(Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - April 10, 2024 Category: Rheumatology Authors: Stefano Soldano, Vanessa Smith, Paola Montagna, Emanuele Gotelli, Rosanna Campitiello, Carmen Pizzorni, Sabrina Paolino, Alberto Sulli, Andrea Cere and Maurizio Cutolo Tags: Correction Source Type: research
Circulating Immune Landscape Profiling in Psoriasis Vulgaris and Psoriatic Arthritis by Mass Cytometry
CONCLUSION: In the circulation of PsA patients, the TN and CD4+ TCM are characterized with more abundant CD28 and CD127, which effectively distinguished PsA from PsV. This may indicate that individuals undergoing PsV could be stratified at high risk of developing PsA based on the circulating levels of CD28 and CD127 on specific cell subsets.PMID:38590608 | PMC:PMC11001477 | DOI:10.1155/2024/9927964 (Source: Journal of Immunology Research)
Source: Journal of Immunology Research - April 9, 2024 Category: Allergy & Immunology Authors: Xudong Sang Tian Gan Gai Ge Dan Li Youming Mei Chun Pan Siyu Long Bibo Xie Xiaobing Yu Zhiming Chen Hongsheng Wang Source Type: research
