Upadacitinib in Rheumatoid Arthritis and Inadequate Response to Conventional Synthetic Disease-Modifying Antirheumatic Drugs: Efficacy and Safety Through 5 Years (SELECT-NEXT)
CONCLUSION: The 5-year benefit-risk profile for upadacitinib in RA remains favorable.PMID:38621793 | DOI:10.3899/jrheum.2023-1062 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 15, 2024 Category: Rheumatology Authors: Gerd R Burmester Filip Van den Bosch John Tesser Anna Shmagel Yanxi Liu Nasser Khan Heidi S Camp Alan Kivitz Source Type: research
Drug survival and change of disease activity using a second janus kinase inhibitor in patients with difficult-to-treat rheumatoid arthritis who failed to a janus kinase inhibitor and subsequent biologics
CONCLUSIONS: Second JAKi could be a therapeutic option in patients with difficult-to-treat RA who have failed to a JAKi and subsequent bDMARDs.PMID:38622706 | DOI:10.1186/s42358-024-00368-w (Source: Adv Data)
Source: Adv Data - April 15, 2024 Category: Epidemiology Authors: Oh Chan Kwon Wonho Choi Soo Min Ahn Ji Seon Oh Seokchan Hong Chang-Keun Lee Bin Yoo Min-Chan Park Yong-Gil Kim Source Type: research
Rheumatology: What You May Have Missed in 2023
Ann Intern Med. 2024 Apr 16. doi: 10.7326/M24-0678. Online ahead of print.ABSTRACTMany patients with rheumatologic conditions receive care from physicians other than rheumatologists. Here we note key findings from 6 studies in rheumatology published in 2023 that offer valuable insights for internal medicine specialists and subspecialists outside of rheumatology. The first study investigated the effect of low-dose glucocorticoids on patients with rheumatoid arthritis (RA) over 2 years and challenged existing perceptions about the risks of glucocorticoids in this setting. The second study focused on the updated guideline for...
Source: Annals of Internal Medicine - April 15, 2024 Category: Internal Medicine Authors: Kafaf Jalali Lisa A Mandl Source Type: research
The Effect of Low-Dose Glucocorticoids Over Two Years on Weight and Blood Pressure in Rheumatoid Arthritis
Ann Intern Med. 2024 Apr;177(4):545. doi: 10.7326/L24-0003.NO ABSTRACTPMID:38621264 | DOI:10.7326/L24-0003 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 15, 2024 Category: Internal Medicine Authors: Daniel Arkfeld Sofia Audrey B Gonzales Katherine Ruddy Source Type: research
The Effect of Low-Dose Glucocorticoids Over Two Years on Weight and Blood Pressure in Rheumatoid Arthritis
Ann Intern Med. 2024 Apr;177(4):545-546. doi: 10.7326/L24-0004.NO ABSTRACTPMID:38621265 | DOI:10.7326/L24-0004 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 15, 2024 Category: Internal Medicine Authors: Kavita Narula Katharine Lazarus Sirazum Choudhury Karim Meeran Source Type: research
The Effect of Low-Dose Glucocorticoids Over Two Years on Weight and Blood Pressure in Rheumatoid Arthritis
Ann Intern Med. 2024 Apr;177(4):546. doi: 10.7326/L24-0005.NO ABSTRACTPMID:38621266 | DOI:10.7326/L24-0005 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 15, 2024 Category: Internal Medicine Authors: Alexander Theophilopoulos Michael R Bubb Source Type: research
The Effect of Low-Dose Glucocorticoids Over Two Years on Weight and Blood Pressure in Rheumatoid Arthritis
Ann Intern Med. 2024 Apr;177(4):546-547. doi: 10.7326/L24-0006.NO ABSTRACTPMID:38621267 | DOI:10.7326/L24-0006 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 15, 2024 Category: Internal Medicine Authors: Andriko Palmowski Maarten Boers John Kirwan Robin Christensen Frank Buttgereit Source Type: research
When Should I Get My Next COVID Vaccine? Data from the SUrveillance of responses to COVID-19 vaCcines in systEmic immunE mediated inflammatory Diseases (SUCCEED)study
CONCLUSION: Ours is the first pan-Canadian IMID assessment of how vaccine history and other factors affect serologic COVID-19 vaccine responses. These findings may help individuals personalize vaccination decisions, including consideration of additional vaccination when >6 months has elapsed since last COVID vaccination/infection.PMID:38621797 | DOI:10.3899/jrheum.2023-1214 (Source: J Rheumatol)
Source: J Rheumatol - April 15, 2024 Category: Rheumatology Authors: Dawn M E Bowdish Vinod Chandran Carol A Hitchon Gilaad G Kaplan J Antonio Avina-Zubieta Paul R Fortin Maggie J Larch é Gilles Boire Anne-Claude Gingras Roya M Dayam Ines Colmegna Luck Lukusa Jennifer L F Lee Dawn P Richards Daniel Pereira Tania H Watts M Source Type: research
Feasibility of physiotherapist-led rheumatology triage: A randomized study
CONCLUSION: Physiotherapist-led triage was feasible, appeared as reliable as rheumatologist triage of referrals for joint pain, and lead to significantly fewer patients requiring in-clinic visits.PMID:38621798 | DOI:10.3899/jrheum.2023-1071 (Source: J Rheumatol)
Source: J Rheumatol - April 15, 2024 Category: Rheumatology Authors: Janet H Roberts Cheri Gun Jennifer E Mackinnon Susan Parlee Volodko Bakowsky Trudy Taylor Claire E H Barber John G Hanly Source Type: research
Upadacitinib in Rheumatoid Arthritis and Inadequate Response to Conventional Synthetic Disease-Modifying Antirheumatic Drugs: Efficacy and Safety Through 5 Years (SELECT-NEXT)
CONCLUSION: The 5-year benefit-risk profile for upadacitinib in RA remains favorable.PMID:38621793 | DOI:10.3899/jrheum.2023-1062 (Source: J Rheumatol)
Source: J Rheumatol - April 15, 2024 Category: Rheumatology Authors: Gerd R Burmester Filip Van den Bosch John Tesser Anna Shmagel Yanxi Liu Nasser Khan Heidi S Camp Alan Kivitz Source Type: research
A nationwide study on immunosenescence biomarkers profile in older adults: ELSI-Brazil
Exp Gerontol. 2024 Apr 13:112433. doi: 10.1016/j.exger.2024.112433. Online ahead of print.ABSTRACTImmunosenescence is a phenomenon caused by changes in the immune system, and part of these changes involves an increase in circulating immunological biomarkers, a process known as "Inflammaging." Inflammaging can be associated with many diseases related to older people. As the older population continues to grow, understanding changes in the immune system becomes essential. While prior studies assessing these alterations have been conducted in countries with Caucasian populations, this investigation marks a pioneering effort. T...
Source: Experimental Gerontology - April 15, 2024 Category: Geriatrics Authors: Maria Luiza Lima-Silva Karen Cec ília Lima Torres Juliana Vaz de Melo Mambrini Nathalia Coimbra de Brot Sara de Oliveira Santos Olindo Assis Martins-Filho Andr éa Teixeira-Carvalho Maria Fernanda Lima-Costa S érgio Viana Peixoto Source Type: research
Upadacitinib in Rheumatoid Arthritis and Inadequate Response to Conventional Synthetic Disease-Modifying Antirheumatic Drugs: Efficacy and Safety Through 5 Years (SELECT-NEXT)
CONCLUSION: The 5-year benefit-risk profile for upadacitinib in RA remains favorable.PMID:38621793 | DOI:10.3899/jrheum.2023-1062 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 15, 2024 Category: Rheumatology Authors: Gerd R Burmester Filip Van den Bosch John Tesser Anna Shmagel Yanxi Liu Nasser Khan Heidi S Camp Alan Kivitz Source Type: research
When Should I Get My Next COVID Vaccine? Data from the SUrveillance of responses to COVID-19 vaCcines in systEmic immunE mediated inflammatory Diseases (SUCCEED)study
CONCLUSION: Ours is the first pan-Canadian IMID assessment of how vaccine history and other factors affect serologic COVID-19 vaccine responses. These findings may help individuals personalize vaccination decisions, including consideration of additional vaccination when >6 months has elapsed since last COVID vaccination/infection.PMID:38621797 | DOI:10.3899/jrheum.2023-1214 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 15, 2024 Category: Rheumatology Authors: Dawn M E Bowdish Vinod Chandran Carol A Hitchon Gilaad G Kaplan J Antonio Avina-Zubieta Paul R Fortin Maggie J Larch é Gilles Boire Anne-Claude Gingras Roya M Dayam Ines Colmegna Luck Lukusa Jennifer L F Lee Dawn P Richards Daniel Pereira Tania H Watts M Source Type: research
Feasibility of physiotherapist-led rheumatology triage: A randomized study
CONCLUSION: Physiotherapist-led triage was feasible, appeared as reliable as rheumatologist triage of referrals for joint pain, and lead to significantly fewer patients requiring in-clinic visits.PMID:38621798 | DOI:10.3899/jrheum.2023-1071 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 15, 2024 Category: Rheumatology Authors: Janet H Roberts Cheri Gun Jennifer E Mackinnon Susan Parlee Volodko Bakowsky Trudy Taylor Claire E H Barber John G Hanly Source Type: research
The Effect of Low-Dose Glucocorticoids Over Two Years on Weight and Blood Pressure in Rheumatoid Arthritis
Ann Intern Med. 2024 Apr;177(4):546-547. doi: 10.7326/L24-0006.NO ABSTRACTPMID:38621267 | DOI:10.7326/L24-0006 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 15, 2024 Category: Internal Medicine Authors: Andriko Palmowski Maarten Boers John Kirwan Robin Christensen Frank Buttgereit Source Type: research
