Retraction Note: Reduced immunomodulation potential of bone marrow-derived mesenchymal stem cells induced CCR4+CCR6+ Th/Treg cell subset imbalance in ankylosing spondylitis
(Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - April 19, 2024 Category: Rheumatology Authors: Yanfeng Wu, Mingliang Ren, Rui Yang, Xinjun Liang, Yuanchen Ma, Yong Tang, Lin Huang, Jichao Ye, Keng Chen, Peng Wang and Huiyong Shen Tags: Retraction Note Source Type: research
Long-term effects of abatacept on atherosclerosis and arthritis in older vs. younger patients with rheumatoid arthritis: 3-year results of a prospective, multicenter, observational study
We aimed to reveal the effect of abatacept (ABT) on atherosclerosis in rheumatoid arthritis (RA) patients, 3-year efficacy for arthritis, and safety in a population of older vs. younger patients. (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - April 17, 2024 Category: Rheumatology Authors: Zento Yamada, Sei Muraoka, Mai Kawazoe, Wataru Hirose, Hajime Kono, Shinsuke Yasuda, Takahiko Sugihara and Toshihiro Nanki Tags: Research Source Type: research
Osteoarthritis and hypertension: observational and Mendelian randomization analyses
The association between osteoarthritis (OA) and hypertension is a subject of ongoing debate in observational research, and the underlying causal relationship between them remains elusive. (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - April 17, 2024 Category: Rheumatology Authors: Zhi-Jie Yang, Yuan Liu, Yan-Li Liu, Bin Qi, Xin Yuan, Wan-Xin Shi and Liu Miao Tags: Research Source Type: research
Integrative analysis of single-cell and bulk transcriptome data reveal the significant role of macrophages in lupus nephritis
We attempted to identify abnormal immune cell components and signaling pathways in lupus nephritis (LN) and to identify potential therapeutic targets. (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - April 12, 2024 Category: Rheumatology Authors: Shuping Wei, Haiyun Shen, Yidan Zhang, Chunrui Liu, Shoushan Li, Jing Yao, Zhibin Jin and Hongliang Yu Tags: Research Source Type: research
Deregulation in adult IgA vasculitis skin as the basis for the discovery of novel serum biomarkers
Immunoglobulin A vasculitis (IgAV) in adults has a variable disease course, with patients often developing gastrointestinal and renal involvement and thus contributing to higher mortality. Due to understudied ... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - April 12, 2024 Category: Rheumatology Authors: Matija Baj želj, Matjaž Hladnik, Rok Blagus, Vesna Jurčić, Ana Markež, Tanya Deniz Toluay, Snežna Sodin-Šemrl, Alojzija Hočevar and Katja Lakota Tags: Research Source Type: research
Urate-lowering therapy, serum urate, inflammatory biomarkers, and renal function in patients with gout following pegloticase discontinuation
We examined ULT use, serum urate (SU), inflammatory biomarkers, and renal function f... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - April 12, 2024 Category: Rheumatology Authors: Emily E. Holladay, Amy S. Mudano, Fenglong Xie, Jingyi Zhang, Ted R. Mikuls, Brian LaMoreaux, Lissa Padnick-Silver and Jeffrey R. Curtis Tags: Research Source Type: research
Correction: Nintedanib downregulates the profibrotic M2 phenotype in cultured monocyte-derived macrophages obtained from systemic sclerosis patients affected by interstitial lung disease
(Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - April 10, 2024 Category: Rheumatology Authors: Stefano Soldano, Vanessa Smith, Paola Montagna, Emanuele Gotelli, Rosanna Campitiello, Carmen Pizzorni, Sabrina Paolino, Alberto Sulli, Andrea Cere and Maurizio Cutolo Tags: Correction Source Type: research
Anxiety and depression symptoms in adolescents and young adults with juvenile idiopathic arthritis: results of an outpatient screening
Previous studies have shown that growing up with rheumatic conditions can fuel dissatisfaction and psychological distress, which in turn affects disease self-management and treatment adherence. Primary objecti... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - April 10, 2024 Category: Rheumatology Authors: Florian Milatz, Jens Klotsche, Martina Niewerth, Claudia Sengler, Daniel Windschall, Tilmann Kallinich, Frank Dressler, Ralf Trauzeddel, Reinhard W. Holl, Ivan Foeldvari, Normi Br ück, Svenja Temming, Toni Hospach, Petra Warschburger, Rainer Berendes, Ga Tags: Research Source Type: research
Usability and preliminary effectiveness of an app-based physical activity and education program for people with hip or knee osteoarthritis – a pilot randomized controlled trial
Hip and knee osteoarthritis (OA) are highly prevalent worldwide. The guidelines recommend physical activity and education as the core treatments for osteoarthritis. Digital health has the potential to engage p... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - April 10, 2024 Category: Rheumatology Authors: F. Weber, C. Kloek, S. Stuhrmann, Y. Blum, C. Gr üneberg and C. Veenhof Tags: Research Source Type: research
Canakinumab treatment real world evidence in 3 monogenic periodic fever syndromes in 2009 –2022: an interim analysis using the French JIR cohort database
Our study aimed to provide real-world evidence on the treatment patterns, effectiveness and safety of canakinumab in France in Familial Mediterranean Fever (FMF), Mevalonate Kinase Deficiency (MKD), and Tumor ... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - April 8, 2024 Category: Rheumatology Authors: Isabelle Kon é-Paut, Sophie Georgin-Lavialle, Alexandre Belot, Magali Jover, Mathilde Pouriel, Laure Lacoin, Pascal Pillet and Véronique Hentgen Tags: Research Source Type: research
Specific isoforms of the ubiquitin ligase gene WWP2 are targets of osteoarthritis genetic risk via a differentially methylated DNA sequence
Transitioning from a genetic association signal to an effector gene and a targetable molecular mechanism requires the application of functional fine-mapping tools such as reporter assays and genome editing. In... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - April 3, 2024 Category: Rheumatology Authors: Jack B. Roberts, Olivia L.G. Boldvig, Guillaume Aubourg, S. Tanishq Kanchenapally, David J. Deehan, Sarah J. Rice and John Loughlin Tags: Research Source Type: research
Effectiveness and safety of mycophenolate mofetil and rituximab combination therapy for immune idiopathic myopathies
Idiopathic inflammatory myopathies (IIM) represent a rare and heterogenous group diseases, and their treatment is not fully defined yet. According to previous small case series, the combination of mycophenolat... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - April 3, 2024 Category: Rheumatology Authors: Corrado Campochiaro, Nicola Farina, Giacomo De Luca, Veronica Batani, Giorgia Trignani, Davide Vignale, Anna Palmisano, Marco Matucci-Cerinic and Lorenzo Dagna Tags: Research Source Type: research
Peptidoglycan in osteoarthritis synovial tissue is associated with joint inflammation
Peptidoglycan (PG) is an arthritogenic bacterial cell wall component whose role in human osteoarthritis is poorly understood. The purpose of this study was to determine if PG is present in synovial tissue of o... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - March 27, 2024 Category: Rheumatology Authors: Meaghan N Holub, Amanda Wahhab, Joseph R Rouse, Rebecca Danner, Lauren G Hackner, Christine B Duris, Mecaila E McClune, Jules M Dressler, Klemen Strle, Brandon L Jutras, Adam I Edelstein and Robert B Lochhead Tags: Research Source Type: research
Deficiency of peripheral CLA+ Tregs and clinical relevance in Behcet ’s syndrome
Autoimmune responses have been suggested to involvement in patients with Behcet ’s syndrome (BS). There has been growing attention towards the roles of cutaneous lymphocyte antigen (CLA)+ regular T cells (Tregs) i... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - March 21, 2024 Category: Rheumatology Authors: Jiachen Li, Feng Sun, Danxue Zhu, Yuke Hou, Gong Cheng, Ping Wang, Xu Jin, Wenyan Zhou, Xiaolin Sun, Zhanguo Li and Tian Liu Tags: Research Source Type: research
Targeting STAT6-mediated synovial macrophage activation improves pain in experimental knee osteoarthritis
Pain from osteoarthritis (OA) is one of the top causes of disability worldwide, but effective treatment is lacking. Nociceptive factors are released by activated synovial macrophages in OA, but depletion of sy... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - March 20, 2024 Category: Rheumatology Authors: Garth Blackler, Yue Lai-Zhao, Joseph Klapak, Holly T. Philpott, Kyle K. Pitchers, Andrew R. Maher, Benoit Fiset, Logan A. Walsh, Elizabeth R. Gillies and C. Thomas Appleton Tags: Research Source Type: research
