Workshop on Post-Acute Sequelae of COVID-19 Breakout Session 5 (Immunologic/Rheumatologic)
Breakout Session 5. This session will focus on the immunological and rheumatological perspectives of post-acute sequelae of COVID-19.Air date: 12/4/2020 10:30:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - November 24, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Workshop on Post-Acute Sequelae of COVID-19 Breakout Session 5
Breakout Session 5. This session will focus on the immunological and rheumatological perspectives of post-acute sequelae of COVID-19.Air date: 12/4/2020 10:30:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - October 22, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Linking TCR Signaling to Variations in Gene Expression
The control of T cell lineage development in the thymus and T cell differentiation pathways following activation are strongly influenced by T cell receptor (TCR) signaling. Yet the details of how variations in the strength of TCR stimulation produce distinct gene expression programs is poorly understood. Dr. Berg ’ s work has focused on understanding the contribution of ITK to this process. ITK is a Tec family tyrosine kinase known to modulate ‘ TCR signal strength ’ ; biochemically, ITK phosphorylates and activates the enzyme phospholipaseC- γ 1. Using a combination of transcription factor activation assays, genomi...
Source: Videocast - All Events - October 14, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Multicellular control of immunological homeostasis
Hari completed his Ph.D. in Cell Biology at the University of Toronto, Canada, where he employed single-molecule imaging techniques to study multimolecular interactions in individual immune cells. Specifically, he focused on how the dynamics of the actin cytoskeleton regulated receptor diffusion and immune cell signal transduction at fast timescales. In 2016, Hari joined Dr. Ron Germain ’ s lab at the NIH, seeking to understand how the immune response was regulated over much larger spatiotemporal scales. Here, Hari transitioned to studying multicellular systems and their emergent properties within complex tissue environm...
Source: Videocast - All Events - September 29, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Strategies for an HIV Cure 2020 (Day 2)
The National Institute of Allergy and Infectious Diseases (NIAID) will host the fifth biennial Strategies for an HIV Cure meeting virtually on November 16-17, 2020. The goal of this meeting is to review research progress by grantees funded through the NIH Martin Delaney Collaboratories for HIV Cure Research program and NIAID ’ s Understanding HIV Rebound P01 grant program. November 17th (Day 2) will feature presentations from NIAID ’ s Understanding HIV Rebound P01 program grantees. It will also feature a special 'flash talk' session to highlight outstanding early-stage investigators in the HIV cure field.Air date: 11/...
Source: Videocast - All Events - September 15, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Strategies for an HIV Cure 2020 (Day 1)
The National Institute of Allergy and Infectious Diseases (NIAID) will host the fifth biennial Strategies for an HIV Cure meeting virtually on November 16-17, 2020. The goal of this meeting is to review research progress by grantees funded through the NIH Martin Delaney Collaboratories for HIV Cure Research program and NIAID ’ s Understanding HIV Rebound P01 grant program. November 16th (Day 1) will feature presentations from the NIH Martin Delaney Collaboratories for HIV Cure Research program grantees.Air date: 11/16/2020 10:00:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - September 15, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
IIG Seminar - Type I interferon induction and exhaustion upon viral infection
Dr. Zuniga ’ s laboratory discovered that, in response to a viral infection, systemic type I interferons (IFN-I) are initially elevated but are subsequently and rapidly silenced despite continuous pathogen replication. They showed that there is an IFN-I refractory (or exhaustion) phase, during which the infected host fails to elevate IFN-I upon secondary unrelated infections, explaining delayed viral control and enhanced susceptibility to opportunistic infections. Dr. Zuniga will present their recent work on the mechanisms underlying the initial IFN-I elevation and its subsequent, rapid, suppression after viral infection...
Source: Videocast - All Events - September 15, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Division of Allergy, Immunology and Transplantation Subcommittee - September 2020
Report from Division Director and Division StaffAir date: 9/14/2020 1:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - September 2, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
IIG Seminar - Immunological Mechanisms of Cancer Defense: Reining in Dynamic Cancer Cell and Microenvironment Reciprocity
IIG Seminar
The immune system employs two distinct defense strategies against infections: microbe-directed pathogen destruction typified by type 1 immunity, and host-directed pathogen containment exemplified by type 2 immunity in induction of tissue repair. Akin to infectious diseases, cancer progresses with cancer cell acquisition of microorganism-like behavior propagating at the expense of the host. While immunological mechanisms of cancer cell destruction are well defined, whether immune-mediated cancer cell containment can be induced is poorly understood. In this presentation, I will discuss how type 2 immunity can be ...
Source: Videocast - All Events - June 25, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
IIG Seminar: Obesity, lipids and anti-tumor immunity
IIG Seminar
The major focus of my research is to understand the interdependence of the immune and metabolic systems, especially in the setting of obesity and cancer. In particular, my research focuses on the effects of altered metabolism, such as in obesity or the tumor microenvironment, on immune cell function, and full circle to the role of innate immune cells in regulating metabolism. Obesity is a leading preventable cause of cancer. Here I will discuss the effects of obesity on anti-tumour immunity in humans and mice. Analysis of tumors in murine and human obesity and found that obesity supresses the anti-tumor NK cell...
Source: Videocast - All Events - June 18, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
IIG Seminar: Defining malaria vaccine responses by single B cell IG sequencing and plasma IgG proteomics
IIG Seminar
Malaria elimination is a global priority and WHO has projected that malaria deaths could double due to COVID19-related health care disruptions. Vaccines have been pivotal for campaigns to eliminate or eradicate other infectious diseases. Malaria transmission blocking vaccines (TBVs) target surface antigens expressed by parasites during their development in mosquitoes in order to interrupt transmission and contribute to malaria elimination. We collected antigen-specific memory B cells from Malian adults immunized with TBV and obtained B cell receptor IG sequences that were used to define the antibody repertoire ...
Source: Videocast - All Events - June 15, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Rain clears pollen from the air, right? Well, this new research will make you think twice.
Everyone with seasonal allergies is familiar with how troublesome pollen grains can be, but new research from the University of Iowa unveils just how insidious fragmented pollen can be. Since pollen grains can break up in high humidity, during storms they are swept up into the storm’s updraft and ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - June 13, 2020 Category: Science Source Type: video
Immunological Mechanisms of Cancer Defense: Reining in Dynamic Cancer Cell and Microenvironment Reciprocity
IIG Seminar
The immune system employs two distinct defense strategies against infections: microbe-directed pathogen destruction typified by type 1 immunity, and host-directed pathogen containment exemplified by type 2 immunity in induction of tissue repair. Akin to infectious diseases, cancer progresses with cancer cell acquisition of microorganism-like behavior propagating at the expense of the host. While immunological mechanisms of cancer cell destruction are well defined, whether immune-mediated cancer cell containment can be induced is poorly understood. In this presentation, I will discuss how type 2 immunity can be ...
Source: Videocast - All Events - June 8, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Division of Allergy, Immunology and Transplantation Subcommittee - June 2020
Report from Division Director and Division StaffAir date: 6/1/2020 1:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - May 7, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
The Biomedical Research Response to COVID-19: A View from NIAID
NIH COVID-19 SIG Lecture Series
NIAID has a long-standing dual mandate to maintain a robust portfolio of research in its key focus areas and to respond to emerging and re-emerging infectious diseases (EIDs). With this mandate, NIAID has also sought to improve EID-response preparedness, working in partnership with other U.S. government research entities, industry, academia, and international public-health organizations. This preparedness planning helped the institute respond rapidly to COVID-19. NIAID tapped existing coronavirus expertise and other assets to stand up research programs spanning basic virology and immunology ...
Source: Videocast - All Events - April 13, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
