IIG Seminar - Cornelia Bergmann
The Bergmann lab researches innate and adaptive immune responses to viral infection of the central nervous system (CNS), with an emphasis on mechanisms contributing to viral persistence and demyelinating disease, similar to multiple sclerosis in human. Control of viral encephalomyelitis or latent/persisting viruses in the central nervous system (CNS) poses a challenge to provide protection while minimizing immune-mediated damage to neurons and glia. Dr. Bergmann ’ s research interests reside in two broad areas of neuroinflammation and central nervous system (CNS) pathology: one investigates innate and adaptive immune res...
Source: Videocast - All Events - February 15, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
IIG Seminar - Exciting Hematopoietic Stem Cells
Prof. Gazit studies hematopoietic stem cells (HSCs) – the adult stem cells that give rise to all types of blood and immune cells. Not only are HSCs of vital importance for the entire blood and immune system, but they are also the functional unit enabling bone marrow transplants. HSCs are already saving tens of thousands of patients every year by using them in bone marrow transplants. Prof. Gazit ’ s lab seeks to directly reprogram blood cells back to HSCs in order to generate novel models for leukemia study and understand HSCs within the immune response. Using advanced molecular biology enables the discovery of key reg...
Source: Videocast - All Events - February 15, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
NIH – FDA COVID SIG Lecture with Donna Farber, Ph.D.
Donna Farber, Ph.D., is the George H. Humphreys, II Professor of Surgical Sciences (in Surgery), Chief, Division of Surgical Sciences and Professor of Microbiology& Immunology at Columbia University. from the speaker: " Research in the laboratory is focused on immunological memory and specifically on memory T cells as essential mediators of protective immunity. While it was previously thought that memory T cells mediate their protective responses through rapid migration and surveillance through tissues, it is now become clear that localization and establishment of non-circulating memory T cells resident in tissue sites is ...
Source: Videocast - All Events - February 10, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
NIH – FDA COVID SIG Lecture with Helen Su, M.D., Ph.D.
Helen Su, M.D., Ph.D., is chief of the Human Immunological Diseases Section in NIAID. The Human Immunological Diseases Section (HIDS) carries out research to understand the molecular mechanisms regulating the human immune system and how their derangements cause disease. They study patients with poorly characterized, inherited immunodeficiencies and autoimmune diseases, often lacking molecular diagnoses.
Major Areas of Research: Defining the molecular mechanisms of new inherited human immunological diseases; Understanding DOCK8 function in health and human disease; Elucidating innate immunoregulatory mechanisms for contro...
Source: Videocast - All Events - February 10, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
NIH – FDA COVID SIG Lecture with Ali Ellebedy, WUSTL
Ali Ellebedy, Ph.D., is Associate Professor, Pathology& Immunology at WUSTL. His research interests are: Defining the cellular and molecular mechanisms that regulate memory B cell heterogeneity and fate; Understanding the rules for eliciting broadly neutralizing B cell responses against rapidly evolving pathogens, such as influenza viruses.Air date: 5/18/2023 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - February 10, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
NIH – FDA COVID SIG Lecture with Michael Diamond, WUSTL
Michael S. Diamond, MD, PhD, is the Herbert S. Gasser Professor, Departments of Medicine, Molecular Microbiology, Pathology& Immunology, WUSTL. Diamond ’ s laboratory studies the molecular basis of disease of globally emerging RNA viruses, and focuses on the interface between pathogenesis and host immunity. He identified many of the key innate and adaptive immune system components that define protection against flaviviruses, and the viral genes that antagonize this response. His laboratory made a seminal discovery by identifying a novel pathogen-associated molecular pattern (lack of 2 ′ -O methylation on the 5 ′ vira...
Source: Videocast - All Events - February 10, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
NIH/FDA IIG Seminar - Viral reservoirs and rebound in a model of perinatal HIV infection
Dr. Chahroudi ’ s research group aims to discover mechanisms of HIV persistence, test translational cure-directed strategies, and uncover immunopathologies caused by Zika virus and SARS-CoV-2 infections using pediatric models and patient samples. Her group ’ s HIV research is centered on mother-to-child transmission of HIV. Using nonhuman primate models of pathogenic and nonpathogenic SIV infections, her group aims to elucidate the mechanisms responsible for breastfeeding transmission. Dr. Chaahroudi has found that sooty mangabeys, a natural SIV host species, rarely transmit SIV from mother to infant. A better understa...
Source: Videocast - All Events - February 8, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
Biomedical History Lecture with Dr. Erling Norrby
A global leader on immunology& vaccines, Dr. Norrby is the former Dean of the Faculty of Medicine at the Karolinska Institute, Stockholm, Sweden. There Norrby was instrumental in the selection process for Nobel Prize recipients in the Physiology of Medicine; and later served as permanent secretary of the Royal Swedish Academy of Sciences, and a board member of the Nobel Foundation. At present, Dr. Norrby is with the Center for History of Science at The Royal Swedish Academy of Sciences; and serves as the Vice Chair of the Board of the J. Craig Venter Institute in La Jolla, California.For more information go tohttps://histo...
Source: Videocast - All Events - February 7, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
NIH/FDA IIG Seminar - Cornelia Bergmann
The Bergmann lab researches innate and adaptive immune responses to viral infection of the central nervous system (CNS), with an emphasis on mechanisms contributing to viral persistence and demyelinating disease, similar to multiple sclerosis in human. Control of viral encephalomyelitis or latent/persisting viruses in the central nervous system (CNS) poses a challenge to provide protection while minimizing immune-mediated damage to neurons and glia. Dr. Bergmann ’ s research interests reside in two broad areas of neuroinflammation and central nervous system (CNS) pathology: one investigates innate and adaptive immune res...
Source: Videocast - All Events - February 6, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
NIH/FDA IIG Seminar - Exciting Hematopoietic Stem Cells
Prof. Gazit studies hematopoietic stem cells (HSCs) – the adult stem cells that give rise to all types of blood and immune cells. Not only are HSCs of vital importance for the entire blood and immune system, but they are also the functional unit enabling bone marrow transplants. HSCs are already saving tens of thousands of patients every year by using them in bone marrow transplants. Prof. Gazit ’ s lab seeks to directly reprogram blood cells back to HSCs in order to generate novel models for leukemia study and understand HSCs within the immune response. Using advanced molecular biology enables the discovery of key reg...
Source: Videocast - All Events - February 6, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
CCR Grand Rounds - Personalized Cellular Therapy for Cancer
CCR Grand Rounds
Antoni Ribas, M.D., Ph.D. is Professor of Medicine, Professor of Surgery, and Professor of Molecular and Medical Pharmacology at the University of California Los Angeles (UCLA), Director of the Tumor Immunology Program at the Jonsson Comprehensive Cancer Center (JCCC), Director of the Parker Inst itute for Cancer Immunotherapy (PICI) Center at UCLA. Dr Ribas is a physician-scientist who conducts laboratory and clinical research in malignant melanoma, focusing on gene engineered T cells, PD-1 blockade and BRAF targeted therapies.
His National Cancer Institute (NCI), State of California and fo undation-sup...
Source: Videocast - All Events - February 2, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
IIG: The diversity of neutrophils
Dr. Hidalgo is interested in the cellular and molecular mechanisms by which innate immune cells and their hematopoietic precursors contribute to organismal physiology and pathology. As a postdoctoral trainee he developed and used live imaging modalities to study acute inflammatory disease and discovered the receptors that mediate early neutrophil recruitment, and the signals that cause acute vascular injury. As an independent researcher at CNIC (Spain), his laboratory further developed tools to study thrombo-inflammation and the dramatic consequences in several organs, including the lung, brain and heart. The Hidalgo lab d...
Source: Videocast - All Events - January 27, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
CCR Grand Rounds
“ Personalized Celular Therapy for Cancer ”
Antoni Ribas, M.D., Ph.D.
PROFESSOR OF MEDICINE WITH TENURE
PROFESSOR OF SURGERY
PROFESSOR OF MOLECULAR AND MEDICAL PHARMACOLOGY
UNIVERSITY OF CALIFORNIA LOS ANGELES (UCLA)
Friday, February 3, 2023
12:00 – 1:00 p.m.
Lipsett Amphitheater
(Masks required)
Also available to view via NIH Videocast.
Antoni Ribas, M.D., Ph.D. is Professor of Medicine, Professor of Surgery, and Professor of Molecular and Medical Pharmacology at the University of California Los Angeles (UCLA), Director of the Tumor Immunology Program at the Jonsson Com prehensive Cancer Center (JCCC), D...
Source: Videocast - All Events - January 24, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
The diversity of neutrophils.
Dr. Hidalgo is interested in the cellular and molecular mechanisms by which innate immune cells and their hematopoietic precursors contribute to organismal physiology and pathology. As a postdoctoral trainee he developed and used live imaging modalities to study acute inflammatory disease and discovered the receptors that mediate early neutrophil recruitment, and the signals that cause acute vascular injury. As an independent researcher at CNIC (Spain), his laboratory further developed tools to study thrombo-inflammation and the dramatic consequences in several organs, including the lung, brain and heart. The Hidalgo lab d...
Source: Videocast - All Events - January 10, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
IIG Seminar - Lineage tracking in rhesus macaques: new insights into natural killer cells and tissue-resident myeloid cells.
Dr. Dunbar ’ s research focuses on understanding the process of hematopoiesis in vivo, as well as on optimizing and improving the safety of gene transfer into primary hematopoietic cells for therapeutic purposes. Her goals are synergistic: insight into the control of hematopoiesis is required to successfully manipulate and genetically modify hematopoietic cells; conversely, genetic marking of hematopoietic stem and progenitor cells has provided novel insights into lineage relationships, stem cell dynamics, and stem cell numbers in vivo that are applicable to gene therapy, stem cell transplantation, and other clinical int...
Source: Videocast - All Events - January 9, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
