NIH Director's Seminar: Of humans and mice: Fundamental mechanisms of tissue-specific antifungal immunity
NIH Director's Seminar Series
Over the past few decades, fungal infections have emerged as major causes of morbidity and mortality in immunosuppressed patients despite the administration of antifungal therapy. This talk will highlight recent advances in our understanding of the cellular and molecular basis of protective host immunity against mucosal and invasive fungal infections. These insights have been gained via enrollment at the NIH Clinical Center of large cohorts of patients with inherited and acquired susceptibility to fungal disease and via corroborating immunological research in clinically relevant mouse models o...
Source: Videocast - All Events - June 5, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
Of humans and mice: Fundamental mechanisms of tissue-specific antifungal immunity
NIH Director's Seminar Series
Over the past few decades, fungal infections have emerged as major causes of morbidity and mortality in immunosuppressed patients despite the administration of antifungal therapy. This talk will highlight recent advances in our understanding of the cellular and molecular basis of protective host immunity against mucosal and invasive fungal infections. These insights have been gained via enrollment at the NIH Clinical Center of large cohorts of patients with inherited and acquired susceptibility to fungal disease and via corroborating immunological research in clinically relevant mouse models o...
Source: Videocast - All Events - June 3, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
Division of Allergy, Immunology and Transplantation Subcommittee - June 2019
Report from Division Director and Division StaffAir date: 6/3/2019 1:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - May 23, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
NIH Director's Seminar: From molecular understanding of multiple sclerosis to personalized treatments
NIH Director's Seminar
Polygenic diseases have complex pathophysiology and disease heterogeneity, where diverse mechanisms drive disability progression in different patients. Effective treatments of such diseases require patient-specific therapies that target all mechanisms contributing to the patient ’ s disease expression. Although many putative pathogenic mechanisms have been identified in central nervous system (CNS) autopsy materials from patients with neuroinflammatory diseases such as multiple sclerosis (MS), current clinical practice cannot measure these processes in living human subjects. This limits drug develo...
Source: Videocast - All Events - April 30, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
NCCIH Integrative Medicine Research Lecture: Bacteria Get on Your Nerves: How Bugs Modulate Pain and Immunity
The National Center for Complementary and Integrative Health (NCCIH) presents the Integrative Medicine Research Lecture Series. The series provides overviews of the current state of research and practice involving complementary health approaches and explores perspectives on the emerging discipline of integrative medicine. Dr. Isaac Chiu is Assistant Professor of Immunology, Department of Immunology, Harvard Medicine School. Dr. Chiu's research focus is in uncovering interactions between the nervous system, the immune system, and microbes, in health and disease. Dr. Chiu will also discuss other aspects of bacterial interact...
Source: Videocast - All Events - April 11, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
RNA degradation controls inflammation
NIH Director's Wednesday Afternoon Lecture Series
Dr. Akira is a director and special appointed professor of Immunology Frontier Research Center. He received his M.D. and Ph.D. from Osaka University. After two years of postdoctoral working in Department of Immunology, University of California at Berkeley, he started to study on IL-6 gene regulation and signaling in the Institute for Molecular and Cellular Biology, Osaka University, and cloned transcription factors, NF-IL6(C/EBP beta) and STAT3. He was a professor in Department of Biochemistry, Hyogo College of Medicine from 1996 to 1999, where he became involved in Toll-li...
Source: Videocast - All Events - March 26, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
NCCIH Lecture: Watch Your Step, There Is New Chemistry Everywhere
NCCIH Integrative Medicine Research Lecture
The characterization of biologically active small molecules (natural products) produced by easily cultured bacteria has been a rewarding avenue for identifying novel therapeutics. The characterization of biologically active small molecules (natural products) produced by easily cultured bacteria has been a rewarding avenue for identifying novel therapeutics, as well as gaining insights into how bacteria interact with the world around them. Large-scale sequencing of bacterial genomic and metagenomic DNA indicates that the traditional pure culture – based approach to studying bact...
Source: Videocast - All Events - February 21, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
Pediatric immune diseases, all genetics?
NIH Director ’ s Wednesday Afternoon Lecture Series
Dr. Fischer is interested in understanding how genetic errors cause vulnerability to microorganisms, autoimmunity, inflammation and allergy, with the dual goal to decipher in vivo immunity in humans and to correct its defects.Air date: 2/20/2019 3:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - February 4, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
Turning immunity on and off
NIH Director ’ s Wednesday Afternoon Lecture Series
Dr. Hubbell uses biomaterials and protein engineering approaches to investigate topics in regenerative medicine and immunotherapeutics. In regenerative medicine, he focuses on biomaterial matrices that mimic the extracellular matrix and on growth factor - extracellular matrix interactions, working in a variety of animal models of regenerative medicine. In immunotherapeutics, he focuses on nanomaterials in vaccines that target lymphoid-resident antigen presenting cells and on protein engineering approaches to deliver antigen to the spleen and liver for inverse vaccines t...
Source: Videocast - All Events - January 17, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
Division of Allergy, Immunology, and Transplantation Subcommittee - January 2019
Report from Division Director and Division StaffAir date: 1/28/2019 1:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - January 9, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
Molecular engineering of immunotherapeutics: from regulation in autoimmunity to immunity to cancer
NIH Director ’ s Wednesday Afternoon Lecture Series
Dr. Hubbell uses biomaterials and protein engineering approaches to investigate topics in regenerative medicine and immunotherapeutics. In regenerative medicine, he focuses on biomaterial matrices that mimic the extracellular matrix and on growth factor - extracellular matrix interactions, working in a variety of animal models of regenerative medicine. In immunotherapeutics, he focuses on nanomaterials in vaccines that target lymphoid-resident antigen presenting cells and on protein engineering approaches to deliver antigen to the spleen and liver for inverse vaccines t...
Source: Videocast - All Events - January 7, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
Translational studies in patients with Autoinflammatory Diseases...from bedside to bench and back
Director's Seminar Series
Dr. Goldbach-Mansky will present the work of her Laboratory of Clinical Immunology and Microbiology. Autoinflammatory diseases are a group of rare immune dysregulatory syndromes that present with unexplained fevers, rashes, joint pain, and inflammation in multiple organs, such as the central nervous system, the eyes, inner ears, bones, fat, blood vessels, lungs, and muscles. Many of the disease symptoms present very early in life, and patients do not have infections or malignacies. The discovery of single gene mutations, which modify the regulation of inflammatory pathways that are triggered by ex...
Source: Videocast - All Events - January 4, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
Cancer, Autoimmunity and Immunology 2019 (Day 2)
This event will bring together basic research scientists, clinical research scientists and front line physicians who will be discussing the latest immunotherapy breakthroughs in the context or initiation of autoimmune disease. Speakers will cover cancer therapy in the context of existing autoimmunity and the triggering of autoimmunity as a result of the cancer therapy.Air date: 4/16/2019 8:30:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - December 19, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
Cancer, Autoimmunity and Immunology 2019 (Day 1)
This event will bring together basic research scientists, clinical research scientists and front line physicians who will be discussing the latest immunotherapy breakthroughs in the context or initiation of autoimmune disease. Speakers will cover cancer therapy in the context of existing autoimmunity and the triggering of autoimmunity as a result of the cancer therapy.Air date: 4/15/2019 8:30:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - December 19, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
Resident Memory CD8 T Cells: Surveillance, Function, and Plasticity
Immunology Interest GroupAir date: 12/12/2018 4:15:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - December 6, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
