IIG Seminar Series Lecture
NIH-FDA Immunology Interest Group Seminar Series.Air date: 9/6/2023 4:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - August 17, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

NIH-FDA Immunology Interest Group Seminar
Weekly Seminar Series for the NIH-FDA Immunology Interest GroupAir date: 9/13/2023 4:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - August 9, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

Influenza Pathogenesis and Therapeutics in Vulnerable Populations
Established in 1950 in honor of former NIH Director Rolla E. Dyer, M.D., a noted authority on infectious diseases, this lectureship, now part of the Wednesday Afternoon Lecture Series, features internationally renowned researchers who have contributed substantially to medical as well as biological knowledge of infectious diseases. The Dyer Lecture is the oldest continuous lecture series at the NIH. Stacey Schultz-Cherry, PhD, is a Full Member and Professor in the Department of Infectious Diseases at St Jude Children ’ s Research Hospital in Memphis, TN as well as Senior Associate Dean for the St Jude Graduate School of...
Source: Videocast - All Events - July 19, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

Sleuthing the Microbiome Reveals Undercover Agents of Oncogenesis
The annual Astute Clinician Lecture was established in 1998 through a gift from the late Dr. Robert W. Miller and his wife, Haruko. It honors U.S. scientists who have observed unusual clinical occurrences and, by investigating them, have opened an important new avenue of research. The lectureship exemplifies how astute clinical observations can lead to innovative research. Speakers are proposed by members of the Medical Executive Committee (MEC) with voting for the top three candidates. Selection from this slate of candidates is made by the NIH Director. An expert in foodborne and intestinal infections, Cynthia Sears is ...
Source: Videocast - All Events - July 19, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

Clinical Center GME Grand Rounds: Disease Discovery at the NIH Clinical Center: Translational Approaches to Rare Diseases
Clinical Center Grand Rounds Graduate Medical Education Grand Rounds Disease Discovery at the NIH Clinical Center: Translational Approaches to Rare Diseases Steven Holland, MD Scientific Director, Division of Intramural Research NIH Distinguished Investigator Immunopathogenesis Section National Institute of Allergy and Infectious DiseasesFor more information go tohttps://clinicalcenter.nih.gov/about/news/grcurrent.htmlAir date: 7/26/2023 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - July 17, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

WALS Lecture- William E. Paul Lecture by Diane Mathis
Dr. Mathis obtained a PhD from the University of Rochester, and performed postdoctoral studies at the Laboratoire de G é n é tique Mol é culaire des Eucaryotes in Strasbourg, France and at Stanford University Medical Center. She returned to Strasbourg at the end of 1983, establishing a laboratory at the LGME [later the Institut de Genetique et de Biologie Moleculare et Cellulaire (IGBMC)] in conjunction with Dr. Christophe Benoist. The lab moved to the Joslin Diabetes Center, Boston in 1999. Through 2008, Dr. Mathis was a Professor of Medicine at Brigham and Women ’ s Hospital and Harvard Medical School, and Associate...
Source: Videocast - All Events - July 17, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

NIH – FDA COVID SIG Lecture: Viral RNA Sensors in Human Immunity to SARS-CoV-2
This is an NIH – FDA COVID-19 SIG seminar talk. Helen Su, M.D., Ph.D., is chief of the Human Immunological Diseases Section in NIAID. LECTURE SUMMARY: Impaired type I IFN responses can lead to life-threatening COVID-19. Previous reports have established that the endosomal viral RNA sensors TLR3 and TLR7 initiate protective type I IFN responses during SARS-CoV-2 infections in humans. However, the role of the cytosolic RIG-I-like receptors (RLRs), which are more broadly expressed, has been less well studied. We investigated rare variants in the genes encoding MDA5, RIG-I, and their downstream signaling adaptor MAVS,from a ...
Source: Videocast - All Events - June 21, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

CCR Grand Rounds: Immune Checkpoint Inhibitor Therapy and the Gut Microbiome: A Complex Relationship with Significant Implications in Cancer Treatment
CCR Grand Rounds “ Immune Checkpoint Inhibitor Therapy and the Gut Microbiome: A Complex Relationship with Significant Implications in Cancer Treatment ” Amiran K. Dzutsev, M.D., Ph.D. Staff Scientist Laboratory of Integrative Cancer Immunology Center for Cancer Research, NCI Friday, June 23, 2023 12:00 – 1:00 p.m. Lipsett Amphitheater The Center for Cancer Research Grand Rounds provides a weekly series of lectures that discuss the most up-to-date research regarding new detection methods and treatment modalities and their potential applications. These lectures are designed to enhance professional effectivenes...
Source: Videocast - All Events - June 14, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

NIH Director's Seminar Series: Exploring the functions of skin as an immunological interface
The skin is a vital barrier against environmental stressors such as thermal changes, sunlight, allergens, toxins, and microbes. An array of cell types including epithelia, fibroblasts, neurons, and vasculature act together to ensure its function. Immune cells have emerged as orchestrators of skin biology that collectively serve to reinforce the barrier against external threats. The composition and function of immune cells are constantly tuned by skin structures, microbial and inflammatory stimuli. In turn, skin immune cells engage in an active dialogue with the tissue to regulate the microbiota, limit microbial invasion an...
Source: Videocast - All Events - June 12, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

Clinical Center Grand Rounds: SARS-Cov-2 Evolution And Potential Variant Emergence In Immunocompromised Individuals
Veronique Nussenblatt, MD, ScM, MHS Chief, Infectious Disease Consult Service Associate Program Director, Infectious Disease Fellowship Director, NIH Residency Electives Program (REP) Director, Clinical Electives Program (CEP) for Medical Students National Institute of Allergy and Infectious Diseases, NIAID Elodie Ghedin, PhD Chief, Systems Genomics Section National Institute of Allergy and Infectious Diseases, NIAIDFor more information go tohttps://clinicalcenter.nih.gov/about/news/grcurrent.htmlAir date: 6/14/2023 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - June 6, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

IIG Seminar - CD3z ITAMs mediate TCR ligand discrimination
Dr Guillaume Gaud is the IIG ’ s selected trainee for the 2022-2023 seminar series. Dr. Gaud completed his PhD in molecular oncology at the University of Tours before joining the laboratory of Dr. Saoudi at Inserm where he described the role of CD226 signaling in the amplification of CD4+ T-cell TCR signaling. As a Research Fellow in the laboratory of Paul Love at NICHD, Dr. Gaud has continued to research constituents of the TCR signaling complex. Dr. Gaud has recently demonstrated that T cells expressing TCRs containing inactivated (non-signaling) CD3z ITAMs (6F-CD3z) lose their ability to discriminate between low and h...
Source: Videocast - All Events - June 5, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

IIG Seminar - Immune calibration of neuroendocrine homeostasis
It has become increasingly evident that interactions between the enteric nervous system (ENS) and the immune system play important roles to modulate inflammatory responses. Such interaction is particularly critical in the context of the intestinal microenvironment given the unique properties of this organ: intestinal tissue is continuously exposed to numerous microbial and food-derived antigens. In order to deal with these stimuli yet maintain normal physiology and function, intestinal responses are tightly regulated by actions of both the immune and nervous systems, which co-localize in the intestinal microenvironment wit...
Source: Videocast - All Events - June 5, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

Division of Allergy, Immunology and Transplantation Subcommittee - June 2023
Report from Division Director and Division StaffAir date: 6/5/2023 1:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - May 19, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

CCR Grand Rounds: Insights Gained from Investigating Genomic Junk, Dr. Naomi Taylor
CCR Grand Rounds “ Insights Gained from Investigating Genomic Junk ” Naomi Taylor, M.D., Ph.D. Senior Investigator Pediatric Oncology Branch Center for Cancer Research, NCI Friday, May 19, 2023 12:00 – 1:00 p.m. Lipsett Amphitheater (Masks required) Also available to view via NIH Videocast. Naomi Taylor received her M.D. and Ph.D. degrees from Yale University, studying the disruption of Epstein-Barr virus (EBV) latency under the direction of Dr. George Miller. She then returned to clinical pediatrics, pursuing training in b one marrow transplantation at Children ’ s Hospital Los Angeles. In 1996, Dr. Taylor...
Source: Videocast - All Events - May 16, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

IIG Seminar - IL-15-induced bystander T cell activation in human viral disease.
Dr. Eui-Cheol Shin investigates mechanisms of immunopathogenesis, immunosenescence, T-cell exhaustion, and human immune monitoring. Dr. Shin and his team have extensively demonstrated the pathological significance of bystander T cell activation in human disease by studying T cell responses in patients infected with viral diseases. His group has found that pre-existing bystander memory CD8+ T cells are unexpectedly activated by cytokines (e.g., IL-15) regardless of their antigen specificity, causing liver cell damage through NKG2D-mediated cytotoxicity. In characterizing IL-15-responsive bystander T cells in the liver micro...
Source: Videocast - All Events - May 11, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video