Innate Lymphoid cell (ILC) subsets Controlled by Dynamic Expression of Master Regulators
Immunonology IG Seminar
Dr. Jinfang Zhu received his Ph.D. in biochemistry and molecular biology from the Shanghai Institute of Biochemistry, Chinese Academy of Sciences. He completed his postdoctoral training at the Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, with late Dr. William E. Paul, studying CD4 T helper cell differentiation controlled by key transcription factors including GATA3 and T-bet. He started his own group in the Laboratory of Immunology as an Earl Stadtman investigator, and is now the section chief of the Molecular and Cellular Immunoregulation Section in the Laborator...
Source: Videocast - All Events - March 16, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
PD-1 Cancer Immunotherapy
NCI Center for Cancer Research Eminent Lecture Series
Gordon J. Freeman, PhD works in the Department of Medical Oncology at Dana-Farber Cancer Institute and is Professor of Medicine at Harvard Medical School. Dr. Freeman earned his BA in Biochemistry and Molecular Biology, and PhD in Microbiology and Molecular Genetics from Harvard University. His research has identified the major pathways that control the immune response by inhibiting T cell activation (PD-1/PD-L1 and B7-2/CTLA-4) or stimulating T cell activation (B7-2/CD28).
In 2000, Dr. Freeman discovered PD-L1 and PD-L2, and showed they were ligands for PD-1, thus def...
Source: Videocast - All Events - March 16, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
From PHD to NPR: Careers in Science Communication and Tips for Communicating Your Research
Ever wondered how to transition from a career in laboratory research to a career in science communication? Or are you happy in the lab, but want to enhance your skills in communicating research to broader audiences?
Join us as NPR's Madeline Sofia details her journey from the bench to a career in science communication, and provides practical tips for researchers to enhance their ability to communicate their science.
Madeline Sofia is an assistant producer on NPR's Science Desk, specifically for Joe's Big Idea. The goal of Joe's Big Idea is to tell scientific stories that explore the minds and motivations of researchers and...
Source: Videocast - All Events - March 13, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
Macrophages and lymphatics: guardians of the tissue microenvironment
Immunonology IG Seminar
Gwen Randolph received her PhD in Cellular and Molecular Pathology from SUNY, Stonybrook, and completed post-doctoral training at the Rockefeller University and Cornell University Medical Center under the mentorship of Ralph Steinman and William Muller. She joined the faculty at Cornell/Weill Medical College Cornell, and then spent 11 years at Mount Sinai School of Medicine, before moving to Washington University in 2011, where she is now an endowed professor, and head of the immunology graduate program in the Department of Pathology and Immunology. Dr. Randolph has made many major contributions to ...
Source: Videocast - All Events - February 16, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
Mechanistic basis of cancer immunotherapy
NIH Director's Wednesday Afternoon Lecture Series
My group ’ s long interest in understanding the cellular mechanisms of the immune response has increasingly focused on the problem of cancer immunology and immunotherapy. We have now established an entire department devoted to this effort, and postdocs in my group seek to understand how checkpoint inhibitors (eg anti-PD-L1), vaccines, immune agonists and their combinations work to produce durable anti-cancer responses.For more information go tohttps://oir.nih.gov/wals/2017-2018/Air date: 4/18/2018 3:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - February 14, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
Sensing from within: how the immune system discriminates friend from foe
NIH Director's Wednesday Afternoon Lecture Series
The Fitzgerald lab is focused on understanding the molecular mechanisms controlling the inflammatory response. We are interested in determining how the immune system discriminates between pathogens, resident microflora and host molecules to both protect the host from infection and avoid damaging inflammatory diseases. We employ multifaceted approaches including immunology, biochemistry, molecular biology and genetics to understand these mechanisms.For more information go tohttps://oir.nih.gov/wals/2017-2018/Air date: 4/25/2018 3:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - February 14, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
Foxo1 regulates commensalism via modulating goblet cell mucus secretion
Immunonology IG Seminar
Dr. Wu completed his M.D. studies in China at Shanghai Jiaotong University School of Medicine, and then studied immunology and matrix biology as a graduate student at Muenster University, Germany. His main focus was T cell migration during the central nervous system (CNS) inflammation. He joined Dr. Vijay Kuchroo ’ s lab in Brigham and Women ’ s Hospital, Harvard Medical School as a postdoctoral fellow where he studied the molecular regulation of T cell differentiation during inflammation and autoimmunity. In 2017, Dr. Wu started a position as an NIH Stadtman Tenure-Track Investigator at the Exp...
Source: Videocast - All Events - February 12, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
Vesicular transmission of viral populations: strength in numbers
Director's Seminar Series
Using interdisciplinary approaches from cell biology to virology to immunology, we investigate the strategies exploited by viruses to successfully transmit themselves among hosts. We recently discovered a novel form of viral transmission in which viruses are transmitted among hosts, not as single infectious units, but as populations of infectious units clustered inside vesicles. We have found this type of en masse transmission to be widespread in nature, taking place both within as well as between hosts and notably leading to enhanced viral infectivity, suppression of host immune responses and the...
Source: Videocast - All Events - February 12, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
Development and Function of Dendritic Cells
Immunonology IG Seminar
Dr. Reizis did his thesis research in immunology with Irun R. Cohen at the Weizmann Institute, and trained as a postdoc with Philip Leder at Harvard Medical School. In late 2003, he started his lab at Columbia University, where he became a tenured Associate Professor in 2010 and a Professor in 2014. In 2015, he joined New York University School of Medicine (NYUSoM) as a Professor in the departments of Pathology and Medicine. Boris is the director of NYUSoM Immunology and Inflammation Training programand the co-Director of the Colton Center for Autoimmunity. In 2016, he has been awarded the inaugural...
Source: Videocast - All Events - January 29, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
Effectors versus Protectors: How Anti-inflammatory Tissue Macrophages Maintain Tissue Homeostasis
Immunonology IG Seminar
Dr. Stefan Uderhardt is a post-doctoral fellow in Dr. Ronald Germain's group within the Laboratory of Systems Biology (LSB), NIAID. Stefan received his medical degree (Dr. med.) from the University of Erlangen-N ü rnberg, Germany in 2011. Early during medical school he developed a passion for immunological research, and thus spent most his spare time working on an experimental thesis on osteoimmunology in the lab of Georg Schett and Gerhard Kr ö nke, investigating the mechanisms of bone loss during inflammatory arthritis. He then started a residency in rheumatology and clinical immunology at the U...
Source: Videocast - All Events - January 19, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
Sex Differences in Immunology & Vaccinology
ORWH Women's Health Seminar SeriesAir date: 3/20/2018 1:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - January 10, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
Single cell analysis of the effector T cell transcriptome
Immunonology IG Seminar
Dr. Thomas Ciucci is a post-doctoral fellow in Dr. R é my Bosselut ’ s group within the Laboratory of Immune Cell Biology (LICB). He received a Ph.D. in Genetics and Immunology from the University of Nice, France in 2012. His doctoral research work investigated the relationship between inflammatory immune cells, the tumor environment and bone tissue. Dr. Ciucci joined Dr. Bosselut ’ s group in 2013 to pursue his interests in the regulation of T cell responses. His research has focused on two aspects of T cell differentiation during the immune response. The first, identified a previously unrecog...
Source: Videocast - All Events - January 9, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
Division of Allergy, Immunology and Transplantation Subcommittee - January 2018
Report from Division Director and Division StaffAir date: 1/29/2018 1:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - January 3, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
T Cell-Based Immunotherapy Approaches for Gliomas
NCI's Center for Cancer Research (CCR) Grand Rounds
As a physician – scientist, Dr. Okada has been dedicated to brain tumor immunology and development of effective immunotherapy for brain tumor patients for over 20 years. His team was one of very first to discover cytotoxic T lymphocyte (CTL) epitopes in glioma-associated and glioma-specific antigens. Dr. Okada also found critical roles for the integrin receptor very late activation antigen (VLA)-4 and the chemokine CXCL10 in facilitating entry of CTLs to the brain tumor site. Dr. Okada has translated these discoveries into a number of innovative immunotherapy clinical s...
Source: Videocast - All Events - December 11, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video
Joseph J. Kinyoun Memorial Lecture - Antibodies Against Ebola and Lassa: A Global Collaboration
Joseph J. Kinyoun Memorial Lecture 2017
Dr. Erica Ollmann Saphire, director of the Viral Hemorrhagic Fever Immunotherapeutic Consortium (VIC), will deliver the 2017 Joseph J. Kinyoun Memorial Lecture.
Her talk, “ Antibodies Against Ebola and Lassa: A Global Collaboration, ” will explore the features of antibodies that protect against these deadly viruses and the ongoing need for scientists to collaborate in this research to establish a complete knowledge base. During the past three years, VIC researchers from dozens of labs on five continents have studied these protective antibodies. The VIC aims to fill critical knowl...
Source: Videocast - All Events - November 27, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video
