Role of FoxP3+ Regulatory T Cells in Modulating Immune Responses to Adeno-Associated Virus Gene Therapy
Human Gene Therapy, Ahead of Print. (Source: Human Gene Therapy)
Source: Human Gene Therapy - April 11, 2024 Category: Genetics & Stem Cells Authors: Maite Mu ñoz-Melero Moanaro Biswas Source Type: research
Engeletin alleviates depressive-like behaviours by modulating microglial polarization via the LCN2/CXCL10 signalling pathway
In conclusion, engeletin can alleviate CSDS-induced depressive-like behaviours by regulating the LCN2/CXCL10 pathway and thereby altering the polarization of microglia. These data suggest that the antidepressant effects of engeletin are correlated with the polarization of microglia, highlighting a potential avenue for future design of antidepressant strategies that specifically target the microglia.PMID:38597406 | DOI:10.1111/jcmm.18285 (Source: Molecular Medicine)
Source: Molecular Medicine - April 10, 2024 Category: Molecular Biology Authors: Jie Zhang Zheng Song Yanchao Huo Guangqiang Li Liming Lu Chuanmei Wei Shuping Zhang Xinfu Gao Xingyue Jiang Yangyang Xu Source Type: research
Post-pandemic trends: Epidemiological and etiological insights into acute respiratory infections in southern China
This study provides valuable insights into the dynamic nature of respiratory pathogens post COVID-19 era.PMID:38598951 | DOI:10.1016/j.diagmicrobio.2024.116293 (Source: Adv Data)
Source: Adv Data - April 10, 2024 Category: Epidemiology Authors: Yuquan Gao Xudong Feng Ting Yuan Min Li Muyun Wei Shuangshuang Li Source Type: research
Engeletin alleviates depressive-like behaviours by modulating microglial polarization via the LCN2/CXCL10 signalling pathway
In conclusion, engeletin can alleviate CSDS-induced depressive-like behaviours by regulating the LCN2/CXCL10 pathway and thereby altering the polarization of microglia. These data suggest that the antidepressant effects of engeletin are correlated with the polarization of microglia, highlighting a potential avenue for future design of antidepressant strategies that specifically target the microglia.PMID:38597406 | PMC:PMC11005460 | DOI:10.1111/jcmm.18285 (Source: J Cell Mol Med)
Source: J Cell Mol Med - April 10, 2024 Category: Molecular Biology Authors: Jie Zhang Zheng Song Yanchao Huo Guangqiang Li Liming Lu Chuanmei Wei Shuping Zhang Xinfu Gao Xingyue Jiang Yangyang Xu Source Type: research
Engeletin alleviates depressive-like behaviours by modulating microglial polarization via the LCN2/CXCL10 signalling pathway
In conclusion, engeletin can alleviate CSDS-induced depressive-like behaviours by regulating the LCN2/CXCL10 pathway and thereby altering the polarization of microglia. These data suggest that the antidepressant effects of engeletin are correlated with the polarization of microglia, highlighting a potential avenue for future design of antidepressant strategies that specifically target the microglia.PMID:38597406 | PMC:PMC11005460 | DOI:10.1111/jcmm.18285 (Source: Molecular Medicine)
Source: Molecular Medicine - April 10, 2024 Category: Molecular Biology Authors: Jie Zhang Zheng Song Yanchao Huo Guangqiang Li Liming Lu Chuanmei Wei Shuping Zhang Xinfu Gao Xingyue Jiang Yangyang Xu Source Type: research
Engeletin alleviates depressive-like behaviours by modulating microglial polarization via the LCN2/CXCL10 signalling pathway
In conclusion, engeletin can alleviate CSDS-induced depressive-like behaviours by regulating the LCN2/CXCL10 pathway and thereby altering the polarization of microglia. These data suggest that the antidepressant effects of engeletin are correlated with the polarization of microglia, highlighting a potential avenue for future design of antidepressant strategies that specifically target the microglia.PMID:38597406 | PMC:PMC11005460 | DOI:10.1111/jcmm.18285 (Source: J Cell Mol Med)
Source: J Cell Mol Med - April 10, 2024 Category: Molecular Biology Authors: Jie Zhang Zheng Song Yanchao Huo Guangqiang Li Liming Lu Chuanmei Wei Shuping Zhang Xinfu Gao Xingyue Jiang Yangyang Xu Source Type: research
Viruses, Vol. 16, Pages 585: Higher-Order Structure of Adeno-Associated Virus Serotype 8 by Hydrogen/Deuterium Exchange Mass Spectrometry
This study demonstrated HDX-MS as a powerful method for probing the structure of the entire rAAV capsid. (Source: Viruses)
Source: Viruses - April 10, 2024 Category: Virology Authors: Tomohiko Ikeda Yuki Yamaguchi Hiroaki Oyama Aoba Matsushita Yasuo Tsunaka Mitsuko Fukuhara Tetsuo Torisu Susumu Uchiyama Tags: Article Source Type: research
