COVID-19: Developing a Vaccine During a Pandemic
COVID-19 Scientific Interest GroupDr. Barouch is the William Bosworth Castle Professor of Medicine and Professor of Immunology at Harvard Medical School and director of the Center for Virology and Vaccine Research at the Beth Israel Deaconess Medical Center. His talk will outline the current state of the COVID-19 vaccine field and will describe the development of the Ad26.COV2.S vaccine — a recombinant, replication-incompetent adenovirus serotype 26 (Ad26) vector encoding a full-length and stabilized SARS-CoV-2 spike protein.My laboratory focuses on studying the immunology and virology of HIV-1 infection and developing n...
Source: Videocast - All Events - February 3, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video

COVID 19 Vaccine Development
My laboratory focuses on studying the immunology and virology of HIV-1 infection and developing novel vaccine strategies. I have also recently demonstrated the therapeutic efficacy of potent monoclonal antibodies and the early seeding of the viral reservoir. My laboratory received three NIH U19 Integrated Preclinical/Clinical AIDS Vaccine Development (IPCAVD) program grants in 2005, 2008, and 2012 to construct alternative serotype adenovirus vaccine vectors, to explore their immunogenicity and protective efficacy in rhesus monkeys, and to advance optimal vaccine candidates into clinical trials. Four phase 1 clinical trials...
Source: Videocast - All Events - December 10, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video

Workshop on Systemic Immunogenicity Considerations for Adeno-Associated Virus (AAV)-Mediated Gene Therapy (Day 2)
This meeting will bring together scientists, therapeutic developers and patient representatives to focus on immunogenicity issues related to the systemic administration of AAV gene therapy products and identify solutions for those issues.For more information go tohttps://events-support.com/events/NCATS_Gene_Therapies_November_2020Air date: 12/1/2020 9:30:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - September 8, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video

Workshop on Systemic Immunogenicity Considerations for Adeno-Associated Virus (AAV)-Mediated Gene Therapy (Day 1)
The National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH) and the Center for Biologics Evaluation and Research (CBER) at the U.S. Food and Drug Administration (FDA) are co-hosting a virtual Workshop on Systemic Immunogenicity Considerations for Adeno-Associated Virus (AAV)-Mediated Gene Therapy. This meeting will bring together scientists, therapeutic developers and patient representatives to focus on immunogenicity issues related to the systemic administration of AAV gene therapy products and identify solutions for those issues.For more information go tohttps://events-supp...
Source: Videocast - All Events - September 8, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video

Workshop on Expanding AAV Manufacturing Capacity for Rare Disease Gene Therapies (Day 1)
The National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH) and Center for Biologics Evaluation and Research (CBER) at the Food and Drug Administration (FDA) are co-hosting a Workshop on Expanding AAV Manufacturing Capacity for Rare Disease Gene Therapies. Current adeno-associated virus (AAV) manufacturing capacity cannot keep pace with the demand for AAV gene therapy clinical trials. The purpose of the meeting is to bring together thought leaders, key stakeholders and innovators to explore obstacles and identify opportunities for expanding the capacity of AAV manufacturing f...
Source: Videocast - All Events - January 22, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video

Workshop on Expanding AAV Manufacturing Capacity for Rare Disease Gene Therapies (Day 2)
The National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH) and Center for Biologics Evaluation and Research (CBER) at the Food and Drug Administration (FDA) are co-hosting a Workshop on Expanding AAV Manufacturing Capacity for Rare Disease Gene Therapies. Current adeno-associated virus (AAV) manufacturing capacity cannot keep pace with the demand for AAV gene therapy clinical trials. The purpose of the meeting is to bring together thought leaders, key stakeholders and innovators to explore obstacles and identify opportunities for expanding the capacity of AAV manufacturing f...
Source: Videocast - All Events - January 22, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video

Unexpected Results from Unconventional Approaches to Adeno-associated Virus Research
Presented by: Dr. Robert Kotin, Voyager Therapeutics and University of Massachusetts Medical School in WorcesterCategory: Philip S. Chen - Innovation & Technology TransferAired date: 10/23/2015 (Source: Videocast - All Events)
Source: Videocast - All Events - October 26, 2015 Category: Journals (General) Tags: Past Events Source Type: video

Unexpected Results from Unconventional Approaches to Adeno-associated Virus Research
The Office of Intramural Research, Office of the Director, NIH, invites you to the tenth annual Philip S. Chen, Jr., Ph.D. Distinguished Lecture on Innovation and Technology Transfer. The lecture will be held on Friday, October 23, 2015, at 10:00 AM in the Masur Auditorium, Building 10, NIH campus in Bethesda, Maryland.Dr. Robert Kotin will present “Unexpected Results from Unconventional Approaches to Adeno-associated Virus Research.” Dr. Kotin was Senior Investigator (1999 – 2014) at the National Heart, Lung and Blood Institute and is currently Vice President of Voyager Therapeutics and Adjunct Professor at the Gene...
Source: Videocast - All Events - September 28, 2015 Category: Journals (General) Tags: Upcoming Events Source Type: video

CC Grand Rounds: (1) Gene Therapy for the Treatment of Radiation Induced Salivary Gland Hypofunction (2) Genome-wide Analysis of Genes and Pathways in the Pathogenesis and Therapy of Head and Neck Cancer
Presented by: (1) Jay Chiorini, PhD, Chief, Adeno-Associated Virus Biology Section, Molecular Physiology and Therapeutics Branch, NIDCR (2) Carter Van Waes, MD, PhD, Clinical Director and Chief, Head and Neck Surgery Branch, NIDCDCategory: Clinical Center Grand RoundsAired date: 09/18/2013 (Source: Videocast - All Events)
Source: Videocast - All Events - September 18, 2013 Category: Journals (General) Tags: Past Events Source Type: video