Chronic recurrent urticaria in a patient with recurrent herpes labialis: complete remission after administration of aciclovir and antihistamines
We present a 41-year-old female patient with chronic recurrent urticaria associated with angioedema and bronchospasm, in whom her herpes genitalis was found to be concurrent within the history and clinical examination. According to the history, the herpes was also recurrent and dated back about a year. Chlamydia trachomatis infection was also found, with serological findings corresponding to vaginal discomfort. Treatment with acyclovir 400mg thrice daily for an initial period of 7 days in combination with desloratadine 5mg daily was started as we observed complete remission of the urticarial rash. Due to worsening vaginal ...
Source: Herpes - October 4, 2023 Category: Infectious Diseases Authors: Georgi Tchernev Simona Kordeva Source Type: research
Case Report: Spectrum of interesting ocular manifestations following COVID-19 vaccination: a case series of real-world presentations
CONCLUSIONS AND IMPORTANCE: Visual symptoms and various ocular adverse events can occur following COVID-19 vaccination, which warrants further investigation and urgent intervention if necessary. We would suggest patients receiving the COVID-19 vaccination be aware of possible ocular complications and report any symptoms, regardless of severity.PMID:37790912 | PMC:PMC10542575 | DOI:10.3389/fcimb.2023.1243055 (Source: Herpes)
Source: Herpes - October 4, 2023 Category: Infectious Diseases Authors: Iqbal Tajunisah Shao Sze Tan Irina Effendi-Tenang Amir Samsudin Kiet-Phang Ling Wee Yong Tan Sunder Ramasamy Kenneth Choong Sian Fong Source Type: research
Chronic recurrent urticaria in a patient with recurrent herpes labialis: complete remission after administration of aciclovir and antihistamines
We present a 41-year-old female patient with chronic recurrent urticaria associated with angioedema and bronchospasm, in whom her herpes genitalis was found to be concurrent within the history and clinical examination. According to the history, the herpes was also recurrent and dated back about a year. Chlamydia trachomatis infection was also found, with serological findings corresponding to vaginal discomfort. Treatment with acyclovir 400mg thrice daily for an initial period of 7 days in combination with desloratadine 5mg daily was started as we observed complete remission of the urticarial rash. Due to worsening vaginal ...
Source: Herpes - October 4, 2023 Category: Infectious Diseases Authors: Georgi Tchernev Simona Kordeva Source Type: research
Prevalence and healthcare utilization in managing herpes zoster in primary care: a retrospective study in an Asian urban population
This study described the prevalence and healthcare utilization in managing HZ in a developed community. A retrospective database review was conducted across a cluster of 8 public primary care clinics in urban Singapore. Data of multi-ethnic Asian patients with a diagnosis code of "herpes zoster" from 2018 to 2020 was extracted from their electronic medical records. Socio-demographic, clinical, visitation, medical leave, prescription, and referral data were analyzed. A total of 2,987 out of 737,868 individuals were diagnosed with HZ over 3 years. The mean age was 59.9 (SD + 15.5) years; 49.2% were male; 78.5% Chinese, 12.2%...
Source: Herpes - October 2, 2023 Category: Infectious Diseases Authors: Xin-Bei Valerie Chan Ngiap Chuan Tan Mark Chung Wai Ng Ding Xuan Ng Yi Ling Eileen Koh Wai Keong Aau Chirk Jenn Ng Source Type: research
Prevalence and healthcare utilization in managing herpes zoster in primary care: a retrospective study in an Asian urban population
This study described the prevalence and healthcare utilization in managing HZ in a developed community. A retrospective database review was conducted across a cluster of 8 public primary care clinics in urban Singapore. Data of multi-ethnic Asian patients with a diagnosis code of "herpes zoster" from 2018 to 2020 was extracted from their electronic medical records. Socio-demographic, clinical, visitation, medical leave, prescription, and referral data were analyzed. A total of 2,987 out of 737,868 individuals were diagnosed with HZ over 3 years. The mean age was 59.9 (SD + 15.5) years; 49.2% were male; 78.5% Chinese, 12.2%...
Source: Herpes - October 2, 2023 Category: Infectious Diseases Authors: Xin-Bei Valerie Chan Ngiap Chuan Tan Mark Chung Wai Ng Ding Xuan Ng Yi Ling Eileen Koh Wai Keong Aau Chirk Jenn Ng Source Type: research
Acute disseminated encephalomyelitis and viral encephalitis: An unusual and misleading imaging
We present a patient who presented seizures and encephalopathy. Brain MRI showed symmetrical white and gray matter lesions. He was treated with acyclovir for viral encephalitis and given immunotherapy for ADEM. The radiological findings may be inconclusive in some cases, hence differential diagnosis of both viral encephalitis and ADEM needs to be considered. Early immunotherapy is required in such fulminant cases. (Source: Clinical Case Reports)
Source: Clinical Case Reports - September 30, 2023 Category: General Medicine Authors: Isha Shukla,
Bhavin Modasia,
Bipin Chaurasia Tags: CASE REPORT Source Type: research
A predictive model of herpes zoster after allogeneic hematopoietic stem cell transplantation: VZV reactivation following antiviral prophylaxis discontinuation
Am J Hematol. 2023 Sep 29. doi: 10.1002/ajh.27090. Online ahead of print.ABSTRACTHerpes zoster (HZ) refers to the rash appearing on dermatomes due to varicella zoster virus (VZV) reactivation. The incidence of HZ is significantly higher in allogeneic hematopoietic stem cell transplantation (allo-HSCT) recipients than in non-HSCT recipients. Although acyclovir prophylaxis is routinely administered to every allo-HSCT recipient for 1 year after transplantation, some individuals eventually develop late-onset HZ after completing prophylaxis. Little information is known about the clinical features of HZ after prophylactic antivi...
Source: Herpes - September 29, 2023 Category: Infectious Diseases Authors: Cheng-Jie Feng Peng Zhao Hai-Xia Fu Chen-Hua Yan Chen-Cong Wang Xiao-Lu Zhu Yun He Feng-Rong Wang Yuan-Yuan Zhang Xiao-Dong Mo Yuan Kong Wei Han Jing-Zhi Wang Yu Wang Huan Chen Yu-Hong Chen Xiang-Yu Zhao Ying-Jun Chang Lan-Ping Xu Kai-Yan Liu Xiao-Jun Hua Source Type: research
A predictive model of herpes zoster after allogeneic hematopoietic stem cell transplantation: VZV reactivation following antiviral prophylaxis discontinuation
Am J Hematol. 2023 Sep 29. doi: 10.1002/ajh.27090. Online ahead of print.ABSTRACTHerpes zoster (HZ) refers to the rash appearing on dermatomes due to varicella zoster virus (VZV) reactivation. The incidence of HZ is significantly higher in allogeneic hematopoietic stem cell transplantation (allo-HSCT) recipients than in non-HSCT recipients. Although acyclovir prophylaxis is routinely administered to every allo-HSCT recipient for 1 year after transplantation, some individuals eventually develop late-onset HZ after completing prophylaxis. Little information is known about the clinical features of HZ after prophylactic antivi...
Source: Herpes - September 29, 2023 Category: Infectious Diseases Authors: Cheng-Jie Feng Peng Zhao Hai-Xia Fu Chen-Hua Yan Chen-Cong Wang Xiao-Lu Zhu Yun He Feng-Rong Wang Yuan-Yuan Zhang Xiao-Dong Mo Yuan Kong Wei Han Jing-Zhi Wang Yu Wang Huan Chen Yu-Hong Chen Xiang-Yu Zhao Ying-Jun Chang Lan-Ping Xu Kai-Yan Liu Xiao-Jun Hua Source Type: research
Mechanistic of Vesicular Ethosomes and Elastic Liposomes on Permeation Profiles of Acyclovir across Artificial Membrane, Human Cultured EpiDerm, and Rat Skin: In Vitro-Ex Vivo Study
Pharmaceutics. 2023 Aug 24;15(9):2189. doi: 10.3390/pharmaceutics15092189.ABSTRACTAcyclovir (ACV) controls cutaneous herpes, genital herpes, herpes keratitis, varicella zoster, and chickenpox. From previously reported ACV formulations, we continued to explore the permeation behavior of the optimized ACV loaded optimized ethosome (ETHO2R) and elastic liposome (ELP3R) and their respective carbopol gels across artificial membrane, cultured human EpiDerm, and rat skin. Transepidermal water loss (TEWL), scanning electron microscopy (SEM), confocal laser scanning microscopy (CLSM), and atomic force microscopy (AFM) were used to ...
Source: Herpes - September 28, 2023 Category: Infectious Diseases Authors: Afzal Hussain Mohammad A Altamimi Obaid Afzal Abdulmalik S A Altamimi Mohhammad Ramzan Tahir Khuroo Source Type: research
Therapeutic Potential of Biochanin A in Herpes Simplex Keratitis
In this study, we report that biochanin A (BCA), a naturally occurring flavonoid compound, provides multifaceted protective effects with anti-viral, anti-inflammatory, anti-oxidative stress and anti-apoptotic activities to alleviate HSK. The results show that BCA significantly inhibited HSV-1 replication in vitro and further proved that BCA principally influenced the early stage of virus infection. We reveal that BCA downregulated the expression of pro-inflammatory factors triggered by HSV-1, including TNF-α, RANTES, IL-1β and IL-6. Furthermore, BCA treatment alleviated oxidative stress and apoptotic arising from HSV-1 i...
Source: Herpes - September 28, 2023 Category: Infectious Diseases Authors: Nan Zhou Deyuan Zheng Qiao You Taige Chen Jiaxuan Jiang Wenhao Shen Di Zhang Junpeng Liu Deyan Chen Kai Hu Source Type: research
Mechanistic of Vesicular Ethosomes and Elastic Liposomes on Permeation Profiles of Acyclovir across Artificial Membrane, Human Cultured EpiDerm, and Rat Skin: In Vitro-Ex Vivo Study
Pharmaceutics. 2023 Aug 24;15(9):2189. doi: 10.3390/pharmaceutics15092189.ABSTRACTAcyclovir (ACV) controls cutaneous herpes, genital herpes, herpes keratitis, varicella zoster, and chickenpox. From previously reported ACV formulations, we continued to explore the permeation behavior of the optimized ACV loaded optimized ethosome (ETHO2R) and elastic liposome (ELP3R) and their respective carbopol gels across artificial membrane, cultured human EpiDerm, and rat skin. Transepidermal water loss (TEWL), scanning electron microscopy (SEM), confocal laser scanning microscopy (CLSM), and atomic force microscopy (AFM) were used to ...
Source: Herpes - September 28, 2023 Category: Infectious Diseases Authors: Afzal Hussain Mohammad A Altamimi Obaid Afzal Abdulmalik S A Altamimi Mohhammad Ramzan Tahir Khuroo Source Type: research
Therapeutic Potential of Biochanin A in Herpes Simplex Keratitis
In this study, we report that biochanin A (BCA), a naturally occurring flavonoid compound, provides multifaceted protective effects with anti-viral, anti-inflammatory, anti-oxidative stress and anti-apoptotic activities to alleviate HSK. The results show that BCA significantly inhibited HSV-1 replication in vitro and further proved that BCA principally influenced the early stage of virus infection. We reveal that BCA downregulated the expression of pro-inflammatory factors triggered by HSV-1, including TNF-α, RANTES, IL-1β and IL-6. Furthermore, BCA treatment alleviated oxidative stress and apoptotic arising from HSV-1 i...
Source: Herpes - September 28, 2023 Category: Infectious Diseases Authors: Nan Zhou Deyuan Zheng Qiao You Taige Chen Jiaxuan Jiang Wenhao Shen Di Zhang Junpeng Liu Deyan Chen Kai Hu Source Type: research
Cytokine storm and severe hepatitis in pregnancy due to herpes simplex virus 2
Infection. 2023 Sep 27. doi: 10.1007/s15010-023-02092-x. Online ahead of print.ABSTRACTCASE PRESENTATION: A pregnant woman developed hepatitis due to a herpes simplex virus 2 primary infection with a severe systemic inflammatory response. Treatment with acyclovir and human immunoglobulin was given and both mother and baby survived.PURPOSE: We provide the first description of the inflammatory response associated with herpetic hepatitis in pregnancy.PMID:37759073 | DOI:10.1007/s15010-023-02092-x (Source: Herpes)
Source: Herpes - September 27, 2023 Category: Infectious Diseases Authors: Alessandra Mularoni Andrea Cona L ùcia Ribeiro Dias Matteo Bulati Rosalia Bus à Salvatore Castelbuono Davide Lo Porto Giada Pietrosi Rosa Liotta Pier Giulio Conaldi Paolo Antonio Grossi Mario Luppi Source Type: research
Cytokine storm and severe hepatitis in pregnancy due to herpes simplex virus 2
AbstractCase presentationA pregnant woman developed hepatitis due to a herpes simplex virus 2 primary infection with a severe systemic inflammatory response. Treatment with acyclovir and human immunoglobulin was given and both mother and baby survived.PurposeWe provide the first description of the inflammatory response associated with herpetic hepatitis in pregnancy. (Source: Infection)
Source: Infection - September 27, 2023 Category: Infectious Diseases Source Type: research
Herpetic Esophagitis: A Cause of Dysphagia in a Malnourished Patient
Cureus. 2023 Aug 21;15(8):e43858. doi: 10.7759/cureus.43858. eCollection 2023 Aug.ABSTRACTHerpetic esophagitis (HE) is an esophageal infection caused by herpes simplex virus (HSV). Although less common, it can occasionally affect immunocompetent hosts. It can manifest as odynophagia and/or dysphagia and should lead to an investigation by upper digestive endoscopy with a biopsy. The authors report a case of a 65-year-old man with a past medical history relevant for schizophrenia, oligophrenia, and malnutrition, and no other history or evidence of immunosuppression, who presented with severe dysphagia over weeks and recent e...
Source: Herpes - September 22, 2023 Category: Infectious Diseases Authors: B árbara Sousa Joana Silva Elsa Ara újo Raquel Costa Andre Calheiros Source Type: research
