Varicella Zoster viral encephalitis without herpes: diagnosis by metagenomic next-generation sequencing of cerebrospinal fluid
Future Microbiol. 2023 Oct 26. doi: 10.2217/fmb-2023-0107. Online ahead of print.ABSTRACTAcute Varicella Zoster viral encephalitis in immunocompetent adult patients without cutaneous herpes has rarely been reported. A 24-year-old female was hospitalized for a headache with a fever but without other obvious symptoms. Multiple routine examinations showed no abnormalities. Lumbar puncture indicated intracranial hypertension. The examination of cerebrospinal fluid by metagenomic next-generation sequencing demonstrated acute Varicella Zoster viral encephalitis. The patient's condition improved by treatment with acyclovir for an...
Source: Herpes - October 26, 2023 Category: Infectious Diseases Authors: Xin Hong Youqi Ji Mengyuan Chen Fang Su Yongze Zhu Yumei Ge Source Type: research
HHV-6B- and HHV-7-associated choroiditis secondary to acute myelogenous leukemia: a case report
We report a case of human herpes virus 6 (HHV-6)- and human herpes virus 7 (HHV-7)-associated choroiditis in an immunocompromised woman. A 42-year-old Chinese woman with a history of acute myelogenous leukemia presented with blurred vision and black floaters in her right eye. Anterior segment examination findings were normal. Ophthalmoscopic examination revealed a subretinal lesion in the superonasal peripapillary region with several punctate hemorrhages. Optical coherence tomography showed a crater-like choroidal protuberance, associated with retinal pigment epithelium rupture and full-thickness retinal edema in the invol...
Source: Herpes - October 24, 2023 Category: Infectious Diseases Authors: Jing Xu Linjiang Chen Tao Cen Yuanping Zeng Qiong Liu Source Type: research
Acute Herpes Simplex Virus Laryngitis Presenting as Airway Obstruction Post Influenza: A Viral Pneumonia
We present a case of HSV laryngitis in a 71-year-old female who presented with septic shock, acute renal failure, and acute hypoxic respiratory failure secondary to Influenza A and bacterial pneumonia for which she required intubation. The hospitalization course included extubation failures due to stridor, a positive cuff leak test resulting in an open tracheostomy, and a laryngeal biopsy confirming HSV infection, which was successfully treated with acyclovir.PMID:37872902 | PMC:PMC10590468 | DOI:10.7759/cureus.45742 (Source: Herpes)
Source: Herpes - October 24, 2023 Category: Infectious Diseases Authors: Tyler W Boyd Sachin M Patil Jason Sinclair Dennis Chairman Nguyen Van T Mohammed Alnijoumi Source Type: research
HHV-6B- and HHV-7-associated choroiditis secondary to acute myelogenous leukemia: a case report
We report a case of human herpes virus 6 (HHV-6)- and human herpes virus 7 (HHV-7)-associated choroiditis in an immunocompromised woman. A 42-year-old Chinese woman with a history of acute myelogenous leukemia presented with blurred vision and black floaters in her right eye. Anterior segment examination findings were normal. Ophthalmoscopic examination revealed a subretinal lesion in the superonasal peripapillary region with several punctate hemorrhages. Optical coherence tomography showed a crater-like choroidal protuberance, associated with retinal pigment epithelium rupture and full-thickness retinal edema in the invol...
Source: Herpes - October 24, 2023 Category: Infectious Diseases Authors: Jing Xu Linjiang Chen Tao Cen Yuanping Zeng Qiong Liu Source Type: research
Acute Herpes Simplex Virus Laryngitis Presenting as Airway Obstruction Post Influenza: A Viral Pneumonia
We present a case of HSV laryngitis in a 71-year-old female who presented with septic shock, acute renal failure, and acute hypoxic respiratory failure secondary to Influenza A and bacterial pneumonia for which she required intubation. The hospitalization course included extubation failures due to stridor, a positive cuff leak test resulting in an open tracheostomy, and a laryngeal biopsy confirming HSV infection, which was successfully treated with acyclovir.PMID:37872902 | PMC:PMC10590468 | DOI:10.7759/cureus.45742 (Source: Herpes)
Source: Herpes - October 24, 2023 Category: Infectious Diseases Authors: Tyler W Boyd Sachin M Patil Jason Sinclair Dennis Chairman Nguyen Van T Mohammed Alnijoumi Source Type: research
A Report of a Case of Segmental Zoster Paresis Demonstrated by Limb Paralysis and a Review of the Literature
Cureus. 2023 Sep 21;15(9):e45691. doi: 10.7759/cureus.45691. eCollection 2023 Sep.ABSTRACTVaricella zoster virus (VZV) lies dormant in our spinal dorsal root ganglia until reactivation occurs and causes herpes zoster. VZV can spread from the dorsal root to the neighboring ventral root and cause subsequent segmental paresis. In this case report, we present the case of a 78-year-old female who was hospitalized after she developed right upper extremity paresis and altered mental status four days after the eruption of a vesicular rash involving the same dermatome. The patient received intravenous acyclovir, gabapentin, and inp...
Source: Herpes - October 23, 2023 Category: Infectious Diseases Authors: Luis F Castro Siddharth A Atwal Jessica M Ramirez Jali Garza Judy Lalmuanpuii Source Type: research
A case of successful hormone therapy for refractory hypotension following viral encephalitis: Case report
We report a rare case of refractory hypotension following herpes simplex virus type 1 encephalitis that was successfully treated with hormone therapy.PATIENT CONCERNS: The patient was a 66-year-old male who was admitted to the hospital because of fever, chills, convulsions, and impaired consciousness. He developed respiratory failure and was intubated. Cerebrospinal fluid metagenomic sequencing confirmed herpes simplex virus type 1 infection. He received piperacillin-tazobactam for anti-infection, acyclovir for antiviral therapy, and dexamethasone for anti-inflammatory therapy. He had repeated episodes of hypotension despi...
Source: Herpes - October 20, 2023 Category: Infectious Diseases Authors: Congcong Zhang Jiangshan Zhang Zhongkai Liao Source Type: research
Fixed Drug Eruption in a Patient Taking Valacyclovir without Cross-Reactivity to Acyclovir
We report a 33-year-old male who presented with a recurrent, localized, brownish-to-erythematous macule and papules on the peri-philtrum area two hours after taking valacyclovir. Three episodes of valacyclovir ingestion for treatment of Herpes simplex virus infection provoked a similar skin rash at the same site. Histopathology results showed vacuolar degeneration in the basal layer of the epidermis, pigmentary incontinence, and perivascular inflammatory cell infiltration in the papillary dermis. Although patch test and skin prick test showed negative responses to acyclovir and valacyclovir, an intradermal test showed a po...
Source: Herpes - October 19, 2023 Category: Infectious Diseases Authors: Yeon-Gu Choi Hyeon Jeong Park Sunmin Yim Heun Joo Lee Young Jun Choi Won-Serk Kim Ga-Young Lee Source Type: research
Fixed Drug Eruption in a Patient Taking Valacyclovir without Cross-Reactivity to Acyclovir
We report a 33-year-old male who presented with a recurrent, localized, brownish-to-erythematous macule and papules on the peri-philtrum area two hours after taking valacyclovir. Three episodes of valacyclovir ingestion for treatment of Herpes simplex virus infection provoked a similar skin rash at the same site. Histopathology results showed vacuolar degeneration in the basal layer of the epidermis, pigmentary incontinence, and perivascular inflammatory cell infiltration in the papillary dermis. Although patch test and skin prick test showed negative responses to acyclovir and valacyclovir, an intradermal test showed a po...
Source: Annals of Dermatology - October 19, 2023 Category: Dermatology Authors: Yeon-Gu Choi Hyeon Jeong Park Sunmin Yim Heun Joo Lee Young Jun Choi Won-Serk Kim Ga-Young Lee Source Type: research
Fixed Drug Eruption in a Patient Taking Valacyclovir without Cross-Reactivity to Acyclovir
We report a 33-year-old male who presented with a recurrent, localized, brownish-to-erythematous macule and papules on the peri-philtrum area two hours after taking valacyclovir. Three episodes of valacyclovir ingestion for treatment of Herpes simplex virus infection provoked a similar skin rash at the same site. Histopathology results showed vacuolar degeneration in the basal layer of the epidermis, pigmentary incontinence, and perivascular inflammatory cell infiltration in the papillary dermis. Although patch test and skin prick test showed negative responses to acyclovir and valacyclovir, an intradermal test showed a po...
Source: Annals of Dermatology - October 19, 2023 Category: Dermatology Authors: Yeon-Gu Choi Hyeon Jeong Park Sunmin Yim Heun Joo Lee Young Jun Choi Won-Serk Kim Ga-Young Lee Source Type: research
