Herpetic Esophagitis: A Cause of Dysphagia in a Malnourished Patient
Cureus. 2023 Aug 21;15(8):e43858. doi: 10.7759/cureus.43858. eCollection 2023 Aug.ABSTRACTHerpetic esophagitis (HE) is an esophageal infection caused by herpes simplex virus (HSV). Although less common, it can occasionally affect immunocompetent hosts. It can manifest as odynophagia and/or dysphagia and should lead to an investigation by upper digestive endoscopy with a biopsy. The authors report a case of a 65-year-old man with a past medical history relevant for schizophrenia, oligophrenia, and malnutrition, and no other history or evidence of immunosuppression, who presented with severe dysphagia over weeks and recent e...
Source: Herpes - September 22, 2023 Category: Infectious Diseases Authors: B árbara Sousa Joana Silva Elsa Ara újo Raquel Costa Andre Calheiros Source Type: research
Supportive care and antiviral treatments in primary herpetic gingivostomatitis: a systematic review
CONCLUSIONS: Although PHGS is a disease with a high worldwide prevalence, the lack of consensus about therapeutic management indicates gaps in existing evidence. Most of the proposed treatment consists in symptomatic drugs with empiric regimens which are ineffective for the viral replication. The main limit to realize randomized clinical trial is due to the rapid onset and remission of the disease. In fact, the diagnostic delay, estimated in 72 h, decreases the effectiveness of any antiviral drugs.CLINICAL RELEVANCE: Out of the five studies included in this systematic review, only one was able to provide some weak evidence...
Source: Herpes - September 21, 2023 Category: Infectious Diseases Authors: Noemi Coppola Tiziana Cantile Daniela Adamo Federica Canfora Stefania Baldares Francesco Riccitiello Gennaro Musella Michele Davide D Mignogna Stefania Leuci Source Type: research
Supportive care and antiviral treatments in primary herpetic gingivostomatitis: a systematic review
CONCLUSIONS: Although PHGS is a disease with a high worldwide prevalence, the lack of consensus about therapeutic management indicates gaps in existing evidence. Most of the proposed treatment consists in symptomatic drugs with empiric regimens which are ineffective for the viral replication. The main limit to realize randomized clinical trial is due to the rapid onset and remission of the disease. In fact, the diagnostic delay, estimated in 72 h, decreases the effectiveness of any antiviral drugs.CLINICAL RELEVANCE: Out of the five studies included in this systematic review, only one was able to provide some weak evidence...
Source: Herpes - September 21, 2023 Category: Infectious Diseases Authors: Noemi Coppola Tiziana Cantile Daniela Adamo Federica Canfora Stefania Baldares Francesco Riccitiello Gennaro Musella Michele Davide D Mignogna Stefania Leuci Source Type: research
Supportive care and antiviral treatments in primary herpetic gingivostomatitis: a systematic review
ConclusionsAlthough PHGS is a disease with a high worldwide prevalence, the lack of consensus about therapeutic management indicates gaps in existing evidence. Most of the proposed treatment consists in symptomatic drugs with empiric regimens which are ineffective for the viral replication. The main limit to realize randomized clinical trial is due to the rapid onset and remission of the disease. In fact, the diagnostic delay, estimated in 72 h, decreases the effectiveness of any antiviral drugs.Clinical relevanceOut of the five studies included in this systematic review, only one was able to provide some weak evidence t...
Source: Clinical Oral Investigations - September 21, 2023 Category: Dentistry Source Type: research
Detection of varicella-zoster virus in two dermatomes of herpes zoster duplex bilateralis in an immunocompetent host
J Dermatol. 2023 Sep 17. doi: 10.1111/1346-8138.16963. Online ahead of print.ABSTRACTAn 85-year-old woman with no history of herpes zoster (HZ) presented with a primary lesion of erythema and blistering on her left thigh and a secondary similar lesion on her right chest which had appeared at 4 and 3 days before presentation, respectively. Tzanck smears for both lesions were positive, revealing multinucleated giant cells. Immunochromatography to detect varicella-zoster virus (VZV) antigen (DermaQuick®VZV) showed positive on the left thigh at initial onset but negative on the right chest at subsequent onset. The latter repe...
Source: Herpes - September 18, 2023 Category: Infectious Diseases Authors: Hiroto Ono Reimon Yamaguchi Kazushi Anzawa Akira Shimizu Source Type: research
Segmental Zoster Paresis Accompanied by Horner's Syndrome
Intern Med. 2023;62(18):2743-2746. doi: 10.2169/internalmedicine.0578-22. Epub 2023 Sep 15.ABSTRACTWe herein report a 90-year-old immunocompromised woman who developed right upper limb weakness and right ptosis with a miotic pupil 1 week after oral therapy for zoster on the right T2 dermatome. The right pupil was dilated with instillation of 1% apraclonidine, indicating Horner's syndrome. The patient was treated with intravenous acyclovir and methylprednisolone. Focal weakness related to zoster, generally known as segmental zoster paresis, improved over five months, but Horner's syndrome remained. We suggest that aggressiv...
Source: Internal Medicine - September 18, 2023 Category: Internal Medicine Authors: Kenta Hanada Yusuke Osaki Koji Fujita Tatsuya Fukumoto Koji Fukushima Hideki Kito Yuishin Izumi Source Type: research
Segmental Zoster Paresis Accompanied by Horner's Syndrome
Intern Med. 2023;62(18):2743-2746. doi: 10.2169/internalmedicine.0578-22. Epub 2023 Sep 15.ABSTRACTWe herein report a 90-year-old immunocompromised woman who developed right upper limb weakness and right ptosis with a miotic pupil 1 week after oral therapy for zoster on the right T2 dermatome. The right pupil was dilated with instillation of 1% apraclonidine, indicating Horner's syndrome. The patient was treated with intravenous acyclovir and methylprednisolone. Focal weakness related to zoster, generally known as segmental zoster paresis, improved over five months, but Horner's syndrome remained. We suggest that aggressiv...
Source: Herpes - September 18, 2023 Category: Infectious Diseases Authors: Kenta Hanada Yusuke Osaki Koji Fujita Tatsuya Fukumoto Koji Fukushima Hideki Kito Yuishin Izumi Source Type: research
Detection of varicella-zoster virus in two dermatomes of herpes zoster duplex bilateralis in an immunocompetent host
J Dermatol. 2023 Sep 17. doi: 10.1111/1346-8138.16963. Online ahead of print.ABSTRACTAn 85-year-old woman with no history of herpes zoster (HZ) presented with a primary lesion of erythema and blistering on her left thigh and a secondary similar lesion on her right chest which had appeared at 4 and 3 days before presentation, respectively. Tzanck smears for both lesions were positive, revealing multinucleated giant cells. Immunochromatography to detect varicella-zoster virus (VZV) antigen (DermaQuick®VZV) showed positive on the left thigh at initial onset but negative on the right chest at subsequent onset. The latter repe...
Source: Herpes - September 18, 2023 Category: Infectious Diseases Authors: Hiroto Ono Reimon Yamaguchi Kazushi Anzawa Akira Shimizu Source Type: research
Segmental Zoster Paresis Accompanied by Horner's Syndrome
Intern Med. 2023;62(18):2743-2746. doi: 10.2169/internalmedicine.0578-22. Epub 2023 Sep 15.ABSTRACTWe herein report a 90-year-old immunocompromised woman who developed right upper limb weakness and right ptosis with a miotic pupil 1 week after oral therapy for zoster on the right T2 dermatome. The right pupil was dilated with instillation of 1% apraclonidine, indicating Horner's syndrome. The patient was treated with intravenous acyclovir and methylprednisolone. Focal weakness related to zoster, generally known as segmental zoster paresis, improved over five months, but Horner's syndrome remained. We suggest that aggressiv...
Source: Internal Medicine - September 18, 2023 Category: Internal Medicine Authors: Kenta Hanada Yusuke Osaki Koji Fujita Tatsuya Fukumoto Koji Fukushima Hideki Kito Yuishin Izumi Source Type: research
Lately Diagnosed Acanthamoeba Keratitis Manifesting as an Intrastromal Corneal Abscess: A Case Report
Eye Contact Lens. 2023 Sep 15. doi: 10.1097/ICL.0000000000001034. Online ahead of print.ABSTRACTA 42-year-old female contact lens wearer presented to a local emergency department with a 3-day history of decreased vision and ocular discomfort in her right eye. She was started on topical fluorometholone and oral acyclovir with initial diagnosis of herpes simplex keratitis. After 3 weeks of worsening symptoms, she was diagnosed with bacterial corneal ulcer and treated with levofloxacin eye drops every 2 hr. After 14 days of no improvement, she was referred to our clinic for further workup. Slitlamp examination demonstrated a ...
Source: Herpes - September 15, 2023 Category: Infectious Diseases Authors: Sepehr Feizi Zahra Karjou Hamed Esfandiari Source Type: research
Amazonian medicinal plants efficiently inactivate Herpes and Chikungunya viruses
This study contributes to the understanding of medicinal species native to the Brazilian Amazon, revealing their potential in combating viral infections that have plagued humanity for centuries (HSV-1) or currently lack specific therapeutic interventions (CHIKV).PMID:37713986 | DOI:10.1016/j.biopha.2023.115476 (Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie)
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 15, 2023 Category: Drugs & Pharmacology Authors: Catielen Paula Pavi Isabella Dai Pr á Rafael Dorighello Cadamuro Isamu Kanzaki Jhuly Wellen Ferreira Lacerda Louis Pergaud Sandjo Roberto Messias Bezerra Jorge Federico Orellana Segovia Gislaine Fongaro Izabella Tha ís Silva Source Type: research
