Drugs for COVID-19: A Publishing Epidemic
As of April 9, PubMed listed 2,868 scientific publications which incorporate the word “COVID”. 323 of these (11.3%) were related to drugs under study for treatment of the disease. No fewer than thirty-one such drugs had been proposed since this pandemic first appeared on the planet four months earlier.
Graph 1 depicts the cumulative numbers of COVID-19 infection (per 100,000 global population) and introductions of relevant drugs into the Literature during February 14 to April 3. Note that both increased by a factor of approximately 16-fold during this period.
In a...
Source: GIDEON blog - April 12, 2020 Category: Databases & Libraries Authors: Uri Blackman Tags: Epidemiology Graphs Source Type: blogs
Cracking the Herpes Encephalitis Code | Causes, Symptoms and Treatment
Conclusion
Herpes encephalitis may rule your body but don't allow the infection to take over your brain. Herpes encephalitis is suppressible and so its symptoms if managed with great attention.
Antiviral drugs such as Zovirax, acyclovir, Valacyclovir are some of the prominently used drugs in suppressing therapy of herpes infection.
You are counseled to see your GP as soon as the very onset of any symptoms described above.You've read Cracking the Herpes Encephalitis Code | Causes, Symptoms and Treatment, originally posted on Pick the Brain | Motivation and Self Improvement. If you've enjoyed this, please visit our site f...
Source: PickTheBrain | Motivation and Self Improvement - June 5, 2019 Category: Consumer Health News Authors: anilkumar Tags: health and fitness Herpes Encephalitis symptoms of herpes encephalitis Source Type: blogs
Herpes infection of the cornea
The clear tissue at the front of the eye is known as the cornea, and it must remain crystal clear in order for an individual to see clearly. The herpes viruses can infect the cornea, causing damage to tissue and possibly causing lasting visual impairment if not quickly identified and treated.
Herpes simplex: the cold sore virus
One of the most common infections of the cornea is caused by the herpes simplex virus (HSV type I and HSV type II), or the cold sore virus. The most common question from patients with HSV infection of the cornea is “How did I get this?” The answer is fairly simple. The virus is everywhere, and e...
Source: Harvard Health Blog - May 20, 2019 Category: Consumer Health News Authors: Emma Davies, MD Tags: Eye Health Infectious diseases Source Type: blogs
TWiV 519: Fishing for viruses in senile
The TWiVomers review a potential role for herpes simplex virus type 1 as a cause of Alzheimer’s Disease, including the finding that amyloid-beta acts as an antiviral by enveloping virus particles. Click arrow to play Download TWiV 519 (58 MB .mp3, 96 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv (Source: virology blog)
Source: virology blog - November 11, 2018 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology acyclovir alzheimer's disease amyloid plaque antiviral beta amyloid herpes simplex virus HSV-1 senile dementia viruses Source Type: blogs
Live the Wheat Belly lifestyle, get off prescription medications
Take a look at the list of medications people have been able to stop by following the Wheat Belly lifestyle.
These represent medications prescribed by doctors to, in effect, “treat” the consequences of consuming wheat and grains. They prescribe drugs to treat inflammation, swelling, skin rashes, gastrointestinal irritation, high blood sugars, airway allergy, joint pain, high blood pressure, leg edema and other abnormal effects caused by wheat and grains.
The list includes anti-inflammatory and pain medication, acid reflux drugs, injectable and oral drugs for diabetes, numerous anti-hypertensive agents, asthma i...
Source: Wheat Belly Blog - October 27, 2018 Category: Cardiology Authors: Dr. Davis Tags: News & Updates autoimmune blood sugar bowel flora cholesterol Gliadin gluten-free grain-free grains Inflammation undoctored Weight Loss wheat belly Source Type: blogs
A cell protein that synthesizes an antiviral ribonucleotide
Some antiviral drugs, like acyclovir for treatment of herpes simplex virus infections, are chain terminators that block RNA or DNA synthesis. They are modified nucleotides that can be incorporated into a growing RNA strand, but no additional nucleotides can be added. Amazingly, a cell protein has been found that can synthesize antiviral chain terminators. Viperin* […] (Source: virology blog)
Source: virology blog - September 27, 2018 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information chain terminator CTP ddhCTP IFN ISG nucleoside polymerase rna synthesis viperin viral virus viruses Source Type: blogs
Tropical Travel Trouble 009 Humongous HIV Extravaganza
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog
aka Tropical Travel Trouble 009
The diagnosis of HIV is no longer fatal and the term AIDS is becoming less frequent. In many countries, people with HIV are living longer than those with diabetes. This post will hopefully teach the basics of a complex disease and demystify some of the potential diseases you need to consider in those who are severely immunosuppressed. While trying to be comprehensive this post can not be exhaustive (as you can imagine any patient with a low ...
Source: Life in the Fast Lane - July 7, 2018 Category: Emergency Medicine Authors: Amanda McConnell Tags: Clinical Cases Tropical Medicine AIDS art cryptococcoma cryptococcus HIV HIV1 HIV2 PEP PrEP TB toxoplasma tuberculoma Source Type: blogs
PrEP: Protection against HIV in a pill?
HIV (the human immunodeficiency virus) weakens the human immune system and destroys the important cells that fight disease and infection. A person can get HIV when bodily fluids — including blood, semen, pre-seminal fluid, rectal fluids, or vaginal fluids of a person with the virus — come in contact with a mucous membrane or damaged tissue. HIV can be transmitted through breast milk, or when a contaminated needle or syringe comes into direct contact with the bloodstream.
There is no cure for HIV, but with proper medical care the virus and its effects can be controlled. HIV transmission can be reduced by consistent use ...
Source: Harvard Health Blog - May 18, 2018 Category: Consumer Health News Authors: Meera Sunder, MBBS, MRCOG Tags: Health HIV Infectious diseases Source Type: blogs
Celebrities get shingles, too
Follow me on Twitter @RobShmerling
Perhaps you heard the news recently that Lin-Manuel Miranda has shingles. Headlines announced this in a variety of ways:
Hamilton creator Lin-Manuel Miranda is suffering from shingles (NY DailyNews)
Lin-Manuel Miranda has shingles; must be quarantined from his baby (today.com)
Lin-Manuel Miranda has shingles, regrets joke about blurred vision (CBS News).
Without more information, these headlines might leave you wondering: is this a serious condition? Is it dangerous for children? Can it lead to blindness?
What is shingles?
The term “shingles” refers to a painful rash caused by infec...
Source: Harvard Health Blog - April 11, 2018 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Health Infectious diseases Skin and Hair Care Vaccines Source Type: blogs
Fuoco di Sant ’ Antonio, shingles, herpes zoster …
Stefano had been complaining recently (last week) about a strange sort of pain/ache in his back that began more or less last Wednesday. We thought he’d pulled a muscle or some such thing. But the pain wasn’t going away. When he’d come home from work, and in the morning when he got out of bed, it was ouch-ouch-ouch. I suggested he at least call our GP, but he didn’t want to bother him. He really thought it was a pulled muscle. Then, on Saturday morning, he asked me to take a look. I found a little rash on the left side of his torso, but he said it wasn’t where the pain was.
And so I didn’...
Source: Margaret's Corner - March 7, 2018 Category: Cancer & Oncology Authors: Margaret Tags: Blogroll shingles turmeric paste Source Type: blogs
Dr. Google: The top 10 health searches in 2017
Follow me on Twitter @RobShmerling
Ever wonder what other people are wondering about? I know I do.
So, here are the top 10 health searches in Google for 2017. And just so you don’t have to look each one up, I’ve provided a brief answer. You’re welcome.
1. What causes hiccups?
I was surprised this one made it to the top 10 list of health searches. Maybe this search is common because hiccups are as mysterious as they are universal. I’ve written about hiccups before, but let’s just say the cause in any individual person is rarely known or knowable. Then again, the reason hiccups stop is also unknown.
Some triggers...
Source: Harvard Health Blog - February 21, 2018 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Health Source Type: blogs
EBV and myeloma stem cells. Chapter 3
This study tells us there are two ways in which a virus, nothing more than a “parasite,” can infect its host cell: 1. actively, by causing “a lytic infection characterized by the release of new progeny virus particles, often upon the lysis of the host cell,” (lysis refers to the destruction of a cell, the host cell in this case), or 2. inactively, which occurs when the virus just sleeps, without reproducing itself.
“Reactivation” occurs when a sleeping virus wakes up and reproduces, stimulated by internal or external factors…but that gets into too much detail, so let’s skip that part.
Here’s anot...
Source: Margaret's Corner - January 23, 2018 Category: Cancer & Oncology Authors: Margaret Tags: Blogroll EBV Epstein-Barr myeloma Source Type: blogs
EBV and myeloma stem cells. Chapter 2.
One thing Dr. Biswas discovered is that the subset of EBV-positive (as opposed to the EBV-negative) myeloma cells are the blasted stem cells, which have CD19 on their surface. What does that mean? Simply that we’re not talking about plasma cells here, but about B-cells that have the ability to REPRODUCE themselves, turning into plasma cells (which do not have that ability, btw).
Confused? Well then, let’s have a look at something different.
On page 12, Dr. Biswas discusses the 90% percentage that I mentioned in my previous post. While EBV “is benign in acute stages and latent in chronic stages […], in some cas...
Source: Margaret's Corner - January 18, 2018 Category: Cancer & Oncology Authors: Margaret Tags: Blogroll Dr. Sunetra Biswas EBV myeloma Source Type: blogs
How Long Does Shingles Last In The Elderly?
Shingles is a viral infection that follows a varicella-zoster infection, although it can take decades for symptoms of the secondary disease to emerge. The condition presents as a painful and blistering rash, but it is not life-threatening.
According to the Center for Disease Control, there are nearly one million cases in the United States each year, and almost half of those cases are in older adults over age 60. Some people only see one instance of the illness, while others have recurring symptoms, but 30 percent of Americans will develop shingles at some point in their lifetime.
Duration of Shingles: Timeline of the Viru...
Source: Shield My Senior - December 8, 2017 Category: Geriatrics Authors: Vin Tags: Senior Safety Source Type: blogs
