The trend analysis of neurological disorders as major causes of death and disability according to human development, 1990-2019

This study aims to assess the trends in the incidence rate of neurological disorders in developed and developing countries worldwide during 1990-2019. The age-standardized incidence rate (per 100000 persons) of neurological disorders was the primary outcome, extracted from the Global Burden of Disease database for 189 countries and territories from 1990 to 2019. Using the Human Development Index (HDI), countries were classified into developed (HDI ≥ 0.7) and developing (HDI < 0.7) groups. Longitudinal analysis was performed using the Latent Growth Model (LGM) to assess the change in the incidence rate of neurological disorders over time in these groups. In developed countries, the most increasing rate is related to depressive disorders, with a rising rate of 40.15 in 100000 every five years (p = 0.001). Alzheimer's and dementia, Parkinson and multiple sclerosis are in the next rank, with increasing rates of 8.77, 1.24, and .02, respectively (all p < 0.001). Over time, the significant decreasing trend has been determined related to conducting disorder, attention-deficit and hyperactivity, meningitis, anxiety, and eating disorders, with the rates of - 13.92, - 4.96, - 2.7, - 1.6, and - 1.44, respectively (all p < 0.05). In developing countries, meningitis, conduct disorder, attention-deficit and hyperactivity, stroke, and autism spectrum showed a significant decreasing trend over time, with rates of - 15.45, - 5.84, - 2.56, - 1.86, and - 1.07, respectively (all p <...
Source: Environmental Science and Pollution Research International - Category: Environmental Health Authors: Source Type: research