Machines Treating Patients? It ’s Already Happening

Rayfield Byrd knows when it’s time to wake up every morning. The 68-year-old Oakland, Cal., resident hears a voice from the living room offering a cheery good morning. Except Byrd lives alone. A little after 8 a.m. each day, a small yellow robot named Mabu asks Byrd how he’s doing. Byrd has Type 2 diabetes and congestive heart failure, and about three years ago, he had surgery to implant a microvalve in his heart to keep his blood flowing properly. To stay healthy, he takes four medications a day and needs to exercise regularly. To make sure his heart is still pumping effectively, his doctor needs to stay on top of whether Byrd gets short of breath. But instead of checking in with his doctor all the time, Byrd now talks with Mabu every morning — and sometimes again later in the day. “Mabu keeps me on my toes about remembering to take my medicine,” says Byrd. “And she asks if I’ve had any shortness of breath and other questions pertaining to my health. She keeps me aware of my breathing.” Byrd has been living with Mabu as part of a study for more than a year now, and he’s gotten used to having a daily conversation with the wide-eyed robot, whose eyelids blink like human eyes do to enhance Byrd’s perception that he’s having a conversation with an intelligent machine and not just answering pre-set questions from a computer. Mabu is among the latest examples of what machine learning, or artificial intelligence (AI...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Artificial Intelligence Life Reinvented medicine Source Type: news

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Publication date: May 2020Source: Clinica Chimica Acta, Volume 504Author(s): Damian Jacenik, Jakub FichnaAbstractChemerin is a multifunctional protein involved among others in adipogenesis, angiogenesis and lipid as well as glucose metabolism. Chemerin is an essential factor in promotion of chemotaxis of numerous immune cell types and plays an important role in several pathophysiologic conditions. Chemerin receptors are present on monocytes/macrophages, T cells, natural killer and dendritic cells as well as neutrophils. However, the role of chemerin and chemerin receptors in immune response and gastrointestinal diseases is...
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
ConclusionsPatients with CMS were more likely to present with increased comorbidities. Patients with CMS undergoing CABG were at risk for worse short ‐term secondary postoperative outcomes and reduced long‐term survival. The data supports the need for further investigation for risk reduction surrounding operative revascularization.
Source: Journal of Cardiac Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: ORIGINAL ARTICLE Source Type: research
AbstractThe first successful human heart transplantation was reported on 3 December 1967, by Christiaan Barnard in South Africa. Since then this life ‐saving procedure has been performed in over 120 000 patients. A limitation to the performance of this procedure is the availability of donor hearts with as many as 20% of patients dying before a donor's heart is available for transplant. Today, hearts for transplantation are procured from indiv iduals experiencing donation after brain death (DBD). Interestingly, this, however, was not always the case as the first heart transplants occurred after circulatory dea...
Source: Journal of Cardiac Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: REVIEW ARTICLE Source Type: research
ConclusionUA leads to disruption of Rac1 and Pak1 activity with subsequent actin depolymerization and migration. Thus, use of dietary UA in cancer prevention or as adjuvant therapy is promising.
Source: Molecular Nutrition and Food Research - Category: Food Science Authors: Tags: Research Article Source Type: research
Publication date: Available online 17 February 2020Source: Zoologischer AnzeigerAuthor(s): Iago Bueno da Silva, Sandra Daruiche Buganeme, Ana Maria Costa-LeonardoAbstractNeocapritermes opacus is a Neotropical termite, which feeds on a variety of food sources, including highly decayed wood and humus. Similar to many Termitidae, this species contains a mixed segment in the intestine, an anatomic distinct region composed of both mesenteric and proctodeal tissues. In Neocapritermes spp., a pair of intestinal protrusions referred to as mesenteric sacs are associated with the mixed segment. In the present study, with the aid of ...
Source: A Journal of Comparative Zoology - Category: Zoology Source Type: research
Publication date: Available online 16 February 2020Source: Biosensors and BioelectronicsAuthor(s): Khalil K. Hussain, N.G. Gurudatt, Mahmood H. Akthar, Kyeong-Deok Seo, Deog-Su Park, Yoon-Bo ShimAbstractA robust amperometric sensor was developed for the lactate detection in the extracellular matrix of cancer cells. The sensor was fabricated by separately immobilizing nicotinamide adenine dinucleotide (NAD+) onto a carboxylic acid group and lactate dehydrogenase (LDH) onto an amine group of bi-functionalized conducting polymer (poly 3-(((2,2':5′,2″-terthiophen)-3′-yl)-5-aminobenzoic acid (pTTABA)) composit...
Source: Biosensors and Bioelectronics - Category: Biotechnology Source Type: research
Publication date: Available online 17 February 2020Source: Journal of Molecular BiologyAuthor(s): Jens Danielsson, Jeffrey Kenneth Noel, Jennifer Michelle Simien, Brendan Michael Duggan, Mikael Oliveberg, José Nelson Onuchic, Patricia Ann Jennings, Ellinor HaglundAbstractLeptin is an important signaling hormone, mostly known for its role in energy expenditure and satiety. Furthermore, leptin plays a major role in other proteinopathies such as cancer, marked hyperphagia, impaired immune function, and inflammation. Despite its biological relevance in human health, there are no NMR resonance assignments of the human pr...
Source: Journal of Molecular Biology - Category: Molecular Biology Source Type: research
Publication date: Available online 17 February 2020Source: Life SciencesAuthor(s): Luiz Antonio Lupi, Maira Smaniotto Cucielo, Henrique Spaulonci Silveira, Letícia Barbosa Gaiotte, Roberta Carvalho Cesário, Fábio Rodrigues Ferreira Seiva, Luiz Gustavo de Almeida ChuffaAbstractToll-like receptors (TLRs) are critical sensors related to inflammation and tumorigenesis. Among all subtypes, the TLR4 is a highly described transmembrane protein involved in the inflammatory process. The TLR4/myeloid differentiation factor 88 (MyD88) signaling pathway has been implicated in oncogenic events in several tissues an...
Source: Life Sciences - Category: Biology Source Type: research
Publication date: Available online 17 February 2020Source: Inorganic Chemistry CommunicationsAuthor(s): M. Eid, M.B. El-Arnaouty, M. Salah, El-Sayed Soliman, El-Sayed A. HegazyAbstractGamma radiation synthesis of Polyaniline/glycidyl methacrylate [P(ANI/GMA)] and Polyaniline/glycidyl methacrylate/Ag2O (P(ANI/GMA)-Ag2O were prepared by adding different concentrations of AgNO3 to the prepared Polyaniline/glycidyl methacrylate. The formation of the function groups of P(ANI/GMA) and P(ANI/GMA)-Ag2O nanocomposites have been investigated by FT-IR. The X-ray patterns of P(ANI/GMA)-Ag2O nanocomposites showed more than crystalline ...
Source: Inorganic Chemistry Communications - Category: Chemistry Source Type: research
New J. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0NJ00240B, PaperXiuhui Yin, Xianglong Li, chunling zhu, Xucong Lin, Zenghong Xie Nanotheranostic agents with integration of diagnostic and therapeutic components into one single ultrasmall nanoparticle hold great promise in cancer imaging and therapy, but still remain challenging. Here, Ag2Se@BSA-RGD quantum dots... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - New J. Chem. latest articles - Category: Chemistry Authors: Source Type: research
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