Aspirin Use Tied to Longer Bladder, Breast Cancer Survival
However, aspirin use in older adults not tied to incidence of various cancer types (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - January 27, 2021 Category: Cancer & Oncology Tags: Gynecology, Oncology, Pharmacy, Urology, Journal, Source Type: news

Regular aspirin use can lower risk for death in bladder, breast cancers, study finds
People who take aspirin at least three times per week are more likely to survive bladder cancer, according to an analysis published Friday by JAMA Network Open. (Source: Health News - UPI.com)
Source: Health News - UPI.com - January 15, 2021 Category: Consumer Health News Source Type: news

Bladder cancer -- When to use chemotherapy
(Charit é - Universit ä tsmedizin Berlin) In patients with bladder cancer, chemotherapy effectiveness is partially determined by the body's immune system response to the malignancy. This is the conclusion of research conducted by a team of scientists from Charit é -- Universit ä tsmedizin Berlin and the Berlin Institute of Health. The findings, which have been published in Science Translational Medicine*, can be used to predict treatment success and may increase survival in patients with bladder cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 14, 2021 Category: Cancer & Oncology Source Type: news

MD Anderson and UroGen Pharma announce strategic research collaboration to advance investigational treatment for high-grade bladder cancer
(University of Texas M. D. Anderson Cancer Center) MD Anderson and UroGen today announced a strategic three-year collaboration agreement to advance combination immunotherapy, delivered directly into the bladder, for the treatment of high-grade non-muscle invasive bladder cancer. The collaboration will work through MD Anderson's immunotherapy platform to design pre-clinical and clinical studies. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 13, 2021 Category: International Medicine & Public Health Source Type: news

Bladder cancer symptoms: Is your pee brown? You could be at risk of the deadly disease
BLADDER cancer is the tenth most common cancer in the UK, with around 10,000 people diagnosed with it every year. One of the main symptoms is a colour change in your urine. (Source: Daily Express - Health)
Source: Daily Express - Health - January 8, 2021 Category: Consumer Health News Source Type: news

Bladder cancer symptoms: The colour of your urine could pinpoint the deadly disease
BLADDER cancer is twice as likely to occur in men than women, especially for those over the age of 50. Would you know what to look for in order to seek medical treatment? Find out here. (Source: Daily Express - Health)
Source: Daily Express - Health - December 17, 2020 Category: Consumer Health News Source Type: news

Physicians often miss rad therapy side effects
Physicians often missed key side effects of radiation therapy in patients with...Read more on AuntMinnie.comRelated Reading: Skipping rad therapy may not hinder breast cancer survival Radiation therapy takes toll on prostate cancer patients' finances Race, ethnicity vary in radiation therapy trials Radiation therapy access grows, but not in rural areas Daily radiation-chemo helps save bladder in cancer patients (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - December 10, 2020 Category: Radiology Source Type: news

Roche presents exploratory data from the Phase III IMvigor010 study in early bladder cancer at the ESMO Immuno-Oncology Virtual Congress 2020
Basel, 10 December 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today presented an exploratory analysis from the Phase III IMvigor010 study evaluating Tecentriq ® (atezolizumab), compared with observation, as an adjuvant (after surgery) monotherapy treatment for people with muscle-invasive urothelial cancer (MIUC) at the European Society for Medical Oncology Immuno-Oncology (ESMO IO) Virtual Congress, 9–12 December 2020. (Source: Roche Investor Update)
Source: Roche Investor Update - December 10, 2020 Category: Pharmaceuticals Source Type: news

Roche presents exploratory data from the Phase III IMvigor010 study in early bladder cancer at the ESMO Immuno-Oncology Virtual Congress 2020
Basel, 10 December 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today presented an exploratory analysis from the Phase III IMvigor010 study evaluating Tecentriq ® (atezolizumab), compared with observation, as an adjuvant (after surgery) monotherapy treatment for people with muscle-invasive urothelial cancer (MIUC) at the European Society for Medical Oncology Immuno-Oncology (ESMO IO) Virtual Congress, 9–12 December 2020. (Source: Roche Media News)
Source: Roche Media News - December 10, 2020 Category: Pharmaceuticals Source Type: news

Novel Gene Therapy Wows for BCG-Unresponsive Bladder Cancer Novel Gene Therapy Wows for BCG-Unresponsive Bladder Cancer
A novel gene therapy for BCG-unresponsive NMIBC, nadofaragene firadenovec, is being suggested as a"new gold standard" for these patients.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - December 8, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Groundbreaking urine test that can spot bladder cancer proves 100% accurate in trials
The pioneering liquid biopsy could replace the dipstick test currently used by GPs (pictured) as a first check for the life-threatening condition. (Source: the Mail online | Health)
Source: the Mail online | Health - December 5, 2020 Category: Consumer Health News Source Type: news

Incidence and risk factors of suicide among patients diagnosed with bladder cancer: a systematic review and meta-analysis - Guo Z, Gu C, Li S, Gan S, Li Y, Xiang S, Gong L, Wang S.
This study aimed to assess how bladder cancer increases suicide risk and to identify the demographic and clinical factors associated with suicidal death among patients with bladder ca... (Source: SafetyLit)
Source: SafetyLit - December 5, 2020 Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news

Burden of non-muscle invasive bladder cancer substantial
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - December 1, 2020 Category: Drugs & Pharmacology Source Type: news

Breast Cancer, CRC Incidence No Different With, Without MS
However, bladder cancer incidence and mortality rates higher among individuals with multiple sclerosis (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - November 30, 2020 Category: Cancer & Oncology Tags: Gastroenterology, Gynecology, Internal Medicine, Neurology, Oncology, Urology, Journal, Source Type: news

Breast Cancer, CRC Incidence No Different With, Without MS
MONDAY, Nov. 30, 2020 -- The incidence of and mortality rates for breast and colorectal cancers do not differ for individuals with and without multiple sclerosis (MS), while bladder cancer incidence and mortality rates are higher for MS patients,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 30, 2020 Category: Pharmaceuticals Source Type: news

Quit Smoking, Your Bladder Will Thank You
THURSDAY, Nov. 26, 2020 -- If you smoke, you significantly increase your odds of developing bladder cancer, experts warn. " Everyone knows smoking causes lung cancer, but they don't always know about bladder cancer, " said Dr. Srinivas Vourganti, a... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - November 26, 2020 Category: General Medicine Source Type: news

MS Has Mixed Impact on Patients' Cancer Risk: Study
WEDNESDAY, Nov. 25, 2020 -- How does having multiple sclerosis (MS) affect a person's odds for cancer? The answer may depend on the type of cancer, new research shows. The study found that MS patients do have much greater odds of developing bladder... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - November 25, 2020 Category: General Medicine Source Type: news

Multiple sclerosis may not put you at risk for breast, colorectal cancers
(American Academy of Neurology) People with multiple sclerosis (MS) may not be at higher risk of developing two of the three cancers that occur most commonly in people with MS, breast and colorectal cancer, than people who don't have the disease, according to a new study published in the November 25, 2020, online issue of Neurology ® , the medical journal of the American Academy of Neurology. However, the study did find that people with MS had a higher incidence of bladder cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 25, 2020 Category: Cancer & Oncology Source Type: news

Cancer Prevention and Screening for Older Adults Cancer Prevention and Screening for Older Adults
This review addresses special considerations regarding prevention and early identification of lung, colorectal, bladder, and kidney cancer for adults aged 65 and older.Journal of the American Geriatrics Society (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 18, 2020 Category: Consumer Health News Tags: Internal Medicine Journal Article Source Type: news

Mesothelioma Surgery with Organ Removal Extends Survival
Removing major organs to achieve a more complete cancer resection did not increase severe complications or hinder survival benefits of aggressive surgery for patients with peritoneal mesothelioma, according to a recent report. The increased complexity of organ resection surgery will not adversely affect long-term outcomes, according to the multicenter study published in Annals of Surgical Oncology. By comparison, an incomplete cytoreduction that can spare the organs is associated with increased mortality and shorter overall survival. The study, which involved 174 patients across 12 specialty centers within the U.S., accent...
Source: Asbestos and Mesothelioma News - November 17, 2020 Category: Environmental Health Authors: Fran Mannino Source Type: news

Houston country star Doug Supernaw dies of cancer at age 60
Country singer Doug Supernaw grew up in Houston’s Inwood Forest. He died Friday, nine months after being diagnosed with lung and bladder... (Source: Reuters: Health)
Source: Reuters: Health - November 14, 2020 Category: Consumer Health News Source Type: news

Sussex research points to new effective breast cancer treatment
(Diamond Light Source) An international five-year study led by scientists at the University of Sussex has provided strong evidence for an effective new target for breast cancer treatment. The study, The structure-function relationship of oncogenic LMTK3 being published in Science Advances, involved researchers from seven institutions across three countries including the UKs Diamond Light Source. It suggests LMTK3 inhibitors could be effectively used for treatment of breast cancer, and potentially other types of cancer such as lung, stomach, thyroid and bladder cancer patients (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 13, 2020 Category: Cancer & Oncology Source Type: news

What Is the Main Cause of Bladder Cancer
? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - November 3, 2020 Category: General Medicine Source Type: news

Patients with Tracey Emin's cancer welcome new treatment plans
Turner Prize nominated artist Tracey Emin said she has an aggressive form of bladder cancer. Some 10,000 Britons a year receive a similar diagnosis and up to two-thirds of them will die within a year. (Source: the Mail online | Health)
Source: the Mail online | Health - November 1, 2020 Category: Consumer Health News Source Type: news

Daily radiation-chemo helps save bladder in cancer patients
A regimen of gemcitabine chemotherapy with daily radiation therapy led to good...Read more on AuntMinnie.comRelated Reading: PET with Axumin boosts prostate cancer outcomes Single-session SBRT speeds treatment of lung metastases Photon IMRT falls short in glioblastoma study Stereotactic body radiation eases spinal cancer pain (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - October 28, 2020 Category: Radiology Source Type: news

Effectiveness of gemcitabine & daily RT for bladder preservation in muscle-invasive bladder cancer
(NRG Oncology) Bladder preservation with trimodality therapy can be a safe and effective alternative to cystectomy for selected patients with muscle-invasive bladder cancer. The phase II NRG Oncology NRG-RTOG 0712 trial evaluated two regimens. One was the prior RTOG standard using 5-flourouracil and cisplatin with twice daily radiation (FCT), and the other a regimen of gemcitabine and daily radiation (GD) which had demonstrated efficacy in single institution clinical trials. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 26, 2020 Category: International Medicine & Public Health Source Type: news

Dual checkpoint blockade promising as pre-surgical approach for certain patients with localized bladder cancer
(University of Texas M. D. Anderson Cancer Center) Phase I trial finds neoadjuvant combination checkpoint inhibitors (anti-CTLA-4 plus anti-PD-1) was well tolerated and showed early signs of activity in certain patients with bladder cancer. These patients cannot be treated with chemotherapy and have no standard treatment options available. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 12, 2020 Category: Cancer & Oncology Source Type: news

Urine-based liquid biopsy test outperforms urine cytology in detecting bladder cancer
(American Association for Cancer Research) Analysis of DNA copy number variants (CNVs) in the cells exfoliated in urine showed better sensitivity and similar specificity in detecting urothelial carcinoma compared with urine cytology (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 9, 2020 Category: Cancer & Oncology Source Type: news

Smoking Tied to Worse Bladder Cancer Outcomes After Surgery
Poor outcomes include lower response rate to chemotherapy, higher mortality, recurrence (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - October 7, 2020 Category: Cancer & Oncology Tags: Oncology, Surgery, Urology, Journal, Source Type: news

Smoking Tied to Worse Bladder Cancer Outcomes After Surgery
WEDNESDAY, Oct. 7, 2020 -- Smoking is tied to worse bladder cancer outcomes following radical cystectomy, according to a review published online Oct. 1 in The Journal of Urology. Giovanni E. Cacciamani, M.D., from the University of Southern... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - October 7, 2020 Category: Pharmaceuticals Source Type: news

Robotic surgery in the COVID-19 era: Urologists take on the challenges
(Wolters Kluwer Health) Robotic surgery plays a major role in modern management of prostate cancer, bladder cancer, and other conditions treated by urologists. But it also poses some special challenges as hospitals resume elective surgery amid the COVID-19 pandemic. Problems and solutions facing urologic robotic surgery in the era of COVID-19 are reviewed inUrology Practice ®, an Official Journal of the American Urological Association (AUA). The journal is published in the Lippincott portfolio by Wolters Kluwer. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 6, 2020 Category: International Medicine & Public Health Source Type: news

Why aren't doctors warning women with bladder cancer that surgery cure can also end their love life?
Thousands of women across the UK with bladder cancer are having life-changing surgery without realising it will end their sex lives, the Mail on Sunday has learned. (Source: the Mail online | Health)
Source: the Mail online | Health - October 3, 2020 Category: Consumer Health News Source Type: news

Bladder Cancer: Developing Drugs and Biologics for Adjuvant Treatment
Draft guidance for industry: Bladder Cancer: Developing Drugs and Biologics for Adjuvant Treatment (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - October 1, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

DNA changes in healthy bladder provide clues on how cancer arises
(Wellcome Trust Sanger Institute) The first comprehensive study of DNA changes in healthy and diseased human bladder tissue has revealed that 'cancer-driving' mutations are common in healthy bladder tissue. The study, conducted by scientists at the Wellcome Sanger Institute, the University of Cambridge and their collaborators, provides an unprecedented view of the first steps towards bladder cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 1, 2020 Category: Cancer & Oncology Source Type: news

Extensive heterogeneity in somatic mutation and selection in the human bladder
This study reveals a rich landscape of mutational processes and selection in normal urothelium with large heterogeneity across clones and individuals. (Source: ScienceNOW)
Source: ScienceNOW - September 30, 2020 Category: Science Authors: Lawson, A. R. J., Abascal, F., Coorens, T. H. H., Hooks, Y., ONeill, L., Latimer, C., Raine, K., Sanders, M. A., Warren, A. Y., Mahbubani, K. T. A., Bareham, B., Butler, T. M., Harvey, L. M. R., Cagan, A., Menzies, A., Moore, L., Colquhoun, A. J., Turner, Tags: Genetics, Medicine, Diseases r-articles Source Type: news

Macroscopic somatic clonal expansion in morphologically normal human urothelium
In this study, we investigated somatic clonal events in morphologically normal human urothelium (MNU; epithelium lining the bladder and ureter) and identified macroscopic clonal expansions. Aristolochic acid (AA), a natural herb-derived compound, was a major mutagenic driving factor in MNU. AA drastically accelerates mutation accumulation and enhances clonal expansion. Mutations in MNU were widely observed in chromatin remodeling genes such as KMT2D and KDM6A but rarely in TP53, PIK3CA, and FGFR3. KMT2D mutations were found to be common in urothelial cells, regardless of whether the cells experience exogenous mutagen expos...
Source: ScienceNOW - September 30, 2020 Category: Science Authors: Li, R., Du, Y., Chen, Z., Xu, D., Lin, T., Jin, S., Wang, G., Liu, Z., Lu, M., Chen, X., Xu, T., Bai, F. Tags: Genetics, Medicine, Diseases r-articles Source Type: news

SIMPONI ARIA ® (golimumab) Approved by the U.S. Food and Drug Administration for Active Polyarticular Juvenile Idiopathic Arthritis and Extension of Its Active Psoriatic Arthritis Indication in Patients 2 Years of Age and Older
HORSHAM, PA, September 30, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that the U.S. Food and Drug Administration (FDA) has approved SIMPONI ARIA® (golimumab) for patients 2 years of age and older for the treatment of active pJIA and has extended the PsA indication for this same patient population. “This latest FDA approval of SIMPONI ARIA for pediatric use in active pJIA and active PsA not only brings a new option to young patients living with these diseases but also adds to the growing body of evidence for this treatment,” said Mathai Mammen, M.D., Ph.D., Glo...
Source: Johnson and Johnson - September 30, 2020 Category: Pharmaceuticals Source Type: news

A Manly Response to Disease
A conventional model of masculinity inhibits some men from expressing their emotional responses to assaults on the body. (Source: NYT Health)
Source: NYT Health - September 24, 2020 Category: Consumer Health News Authors: Susan Gubar Tags: Bladder Cancer Men and Boys Lehman, David Source Type: news

Smoking Reduces Survival Odds After Bladder Cancer Surgery
Title: Smoking Reduces Survival Odds After Bladder Cancer SurgeryCategory: Health NewsCreated: 9/23/2020 12:00:00 AMLast Editorial Review: 9/24/2020 12:00:00 AM (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - September 24, 2020 Category: Cancer & Oncology Source Type: news

Smoking Reduces Survival Odds After Bladder Cancer Surgery
(Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - September 23, 2020 Category: Cancer & Oncology Tags: Oncology, Surgery, Preventive Medicine, News, Source Type: news

Smoking Reduces Survival Odds After Bladder Cancer Surgery
This study is important because while it is known that tobacco smoking is the leading cause of bladder cancer, this is the... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - September 23, 2020 Category: General Medicine Source Type: news

Gene Therapy Clinical Trial for Mesothelioma Moving Forward
This study will compare the effectiveness of the drug against a control group receiving only the gemcitabine and celecoxib. Patients have a one-in-two chance of being randomly assigned to either the adenovirus treatment or the control group. Adenovirus-delivered interferon Alpha-2b is designed as a second- or third-line treatment for patients who have failed in earlier regimens. Patients who previously had aggressive mesothelioma surgery but whose tumors have since progressed would be eligible to enroll. Success at the phase III level would mark the culmination of 20 years of researching and fine tuning gene therapy for us...
Source: Asbestos and Mesothelioma News - September 23, 2020 Category: Environmental Health Authors: Fran Mannino Source Type: news

Immunotherapy Drug Boosts Survival With Bladder Cancer
Title: Immunotherapy Drug Boosts Survival With Bladder CancerCategory: Health NewsCreated: 9/21/2020 12:00:00 AMLast Editorial Review: 9/22/2020 12:00:00 AM (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - September 22, 2020 Category: Cancer & Oncology Source Type: news

Immunotherapy Drug Boosts Survival With Bladder Cancer
(Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - September 21, 2020 Category: Cancer & Oncology Tags: Family Medicine, Oncology, Pharmacy, Research, News, Source Type: news

Immunotherapy Drug Avelumab Boosts Survival With Bladder Cancer
MONDAY, Sept. 21, 2020 -- An immunotherapy drug significantly improved survival in patients with the most common type of bladder cancer, according to a new study. About 550,000 new cases of bladder cancer are diagnosed worldwide each year, making... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - September 21, 2020 Category: General Medicine Source Type: news

How Cancer Shaped Justice Ruth Bader Ginsburg ’s Life and Work
The name Ruth Bader Ginsburg became almost synonymous with strength and stamina as she rose to prominence in judicial and feminist circles throughout her long career. Famously nicknamed the Notorious RBG and known for her grueling fitness regimen, the late Supreme Court justice also struggled with cancer and other health issues for the better part of her time on the bench — culminating with her death on Sept. 18 at the age of 87 of complications from metastatic pancreatic cancer. Ginsburg’s health issues became public in 1999, six years after her appointment to the Supreme Court, when she had surgery for early-...
Source: TIME: Health - September 19, 2020 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized Cancer healthytime remembrance Source Type: news

Immunotherapy improves survival in advanced bladder cancer patients
(Queen Mary University of London) An immunotherapy drug called 'avelumab' has been shown to significantly improve survival in patients with the most common type of bladder cancer, according to results from a phase III clinical trial led by Queen Mary University of London and Barts Cancer Centre, UK. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 18, 2020 Category: International Medicine & Public Health Source Type: news

Prostate cancer symptoms: What’s waking you up in the night? Sign of the deadly disease
PROSTATE cancer develops at the base of the bladder, surrounding the first part of the urethra - the tube that carries urine and semen. Do you find it difficult to sleep throughout the night? Here's a sign linked to the deadly disease. (Source: Daily Express - Health)
Source: Daily Express - Health - September 16, 2020 Category: Consumer Health News Source Type: news

If PPIs Are Onboard, Atezolizumab May Not Work for Bladder Cancer If PPIs Are Onboard, Atezolizumab May Not Work for Bladder Cancer
Your patients with atezolizumab-treated bladder cancer may not benefit if they are on a PPI.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - September 15, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Cigarette smoking associated with worse outcomes for bladder cancer patients after surgery
(University of Southern California - Health Sciences) Study from Keck Medicine of USC links smoking with a higher risk of death and cancer recurrence, and less responsiveness to chemotherapy. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - September 15, 2020 Category: Cancer & Oncology Source Type: news