Researchers find adult stem cell characteristics in aggressive cancers from different tissues
UCLA researchers have discovered  genetic similarities between the adult stem cells responsible for maintaining and repairing epithelial tissues — which line all of the organs and cavities inside the body — and the cells that drive aggressive epithelial cancers. Their findings could bring about a better understanding of how ag gressive, treatment-resistant cancers develop and progress, and could eventually lead to new drugs for a range of advanced epithelial cancers such as lung, prostate and bladder cancers. The study, led by senior authors Owen Witte and Thomas Graeber, both of the  UCLA E...
Source: UCLA Newsroom: Health Sciences - September 18, 2018 Category: Universities & Medical Training Source Type: news

Which Is Best Neoadjuvant Chemo in Bladder Cancer? Which Is Best Neoadjuvant Chemo in Bladder Cancer?
A nonstandard neoadjuvant chemotherapy was associated with higher complete response rates and more downstaging in patients with muscle-invasive bladder cancer.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 10, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Bladder cancer survivor seeks a kidney - with a 5,000 sq ft Time Square billboard  
Marc Weiner, 53, needs a kidney transplant. Rather than spend the next five to eight years on a waiting list with 100,000 sick New Yorkers, he got creative and took out a Time Square ad for a donor. (Source: the Mail online | Health)
Source: the Mail online | Health - August 31, 2018 Category: Consumer Health News Source Type: news

Robotic vs Open Cystectomy for Bladder Cancer Robotic vs Open Cystectomy for Bladder Cancer
Dr Lowenfels comments on the RAZOR trial, which compares robotic versus conventional surgery for bladder cancer.Medscape General Surgery (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 31, 2018 Category: Consumer Health News Tags: General Surgery Viewpoint Source Type: news

Moffitt researchers compare chemotherapy regimens for best outcomes in invasive bladder cancer
(H. Lee Moffitt Cancer Center& Research Institute) Patients with muscle-invasive bladder cancer have been shown to benefit from chemotherapy prior to surgical removal of the bladder. But which type of chemotherapy leads to the best outcomes in terms of complete response rates or cancer control? Moffitt Cancer Center researchers examined data from more than 800 surgical patients with advanced bladder cancer. The results, published online by JAMA Oncology, show higher likelihoods of complete response or down-staging associated with a chemotherapeutic combination called ddMVAC. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - August 31, 2018 Category: Cancer & Oncology Source Type: news

Discovery could lead to higher immunotherapy response rates for bladder cancer patients
(The Mount Sinai Hospital / Mount Sinai School of Medicine) Mount Sinai researchers have discovered that a particular type of cell present in bladder cancer may be the reason why so many patients do not respond to the groundbreaking class of drugs known as PD-1 and PD-L1 immune checkpoint inhibitors, which enable the immune system to attack tumors. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 29, 2018 Category: International Medicine & Public Health Source Type: news

Prostate cancer warning - how many toilet trips is normal? Are you at risk?
PROSTATE cancer symptoms include difficulty passing urine, finding blood in the urine, or having to make more toilet trips than usual. But what is a normal amount of times to empty your bladder? (Source: Daily Express - Health)
Source: Daily Express - Health - August 27, 2018 Category: Consumer Health News Source Type: news

African Americans Urged To Consider Clinical Trials
An initiative launched today encourages newly-diagnosed African American cancer patients in Maryland to consider clinical trials as the first-line option, not the last resort. The ads are intended to reward those progressive physicians who are actively supporting their patients ’ access to the most advanced options for improved care, including clinical trials for prostate, bladder and kidney cancer.08/23/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - August 23, 2018 Category: Urology & Nephrology Source Type: news

Simple test could identify bladder cancer patients who won't respond to immunotherapy
(University of Sussex) Patients who are unlikely to benefit from a commonly used immunotherapy for bladder cancer could be identified by a simple blood test, according to researchers at Brighton and Sussex Medical School (BSMS). (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - August 21, 2018 Category: Cancer & Oncology Source Type: news

Testing turns up heavy metals in baby food; what Consumer Reports says parents need to know
Testing of dozens of the most popular packaged foods for babies and toddlers turned up noticeable and even “worrisome” levels of lead and other heavy metals, according to the watchdog Consumer Reports. Over the course of a child's development, exposure to heavy metals increases the likelihood of developing cancer, particularly lung cancer, bladder cancer and kidney cancer, and increases the risks of issues with neurological development,08/17/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - August 17, 2018 Category: Urology & Nephrology Source Type: news

Locoregional Recurrence Rates Vary Based on Several Factors in Bladder Cancer
A meta-analysis identified several factors that are correlated with locoregional recurrence in patients with nonmetastatic muscle-invasive bladder cancer. (Source: CancerNetwork)
Source: CancerNetwork - August 16, 2018 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news

Is Marital Status Associated With Bladder Cancer Outcome?
An existing body of literature shows that marital status and related social support are connected with disease outcomes. (Source: CancerNetwork)
Source: CancerNetwork - August 9, 2018 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news

Doxorubicin disrupts the immune system to cause heart toxicity
(University of Alabama at Birmingham) Doxorubicin is a chemotherapy drug used in ovarian, bladder, lung, thyroid and stomach cancers, but it carries a harmful side effect. The drug causes a dose-dependent heart toxicity that can lead to congestive heart failure. Researchers have found an important contributor to that heart pathology -- disruption of the metabolism that controls immune responses in the spleen and heart. This dysregulated immunometabolism impairs resolution of inflammation, and chronic, non-resolving inflammation leads to advanced heart failure. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - August 6, 2018 Category: Biology Source Type: news

Bladder cancer warning - three things you should look out for in your wee
BLADDER cancer symptoms are usually spotted by checking your urine after using the toilet. But what signs are you exactly looking out for? These are the most common bladder cancer symptoms, including finding blood in your wee. (Source: Daily Express - Health)
Source: Daily Express - Health - August 2, 2018 Category: Consumer Health News Source Type: news

Medical News Today: What are the symptoms of late stage bladder cancer?
The symptoms of stage 4 bladder cancer include tiredness, weakness, and pain. Stage 4 is the most advanced stage of cancer. The standard treatment for late-stage cancer is chemotherapy, but treatment will often focus on palliative care. Learn more about the symptoms of stage 4 bladder cancer and the survival rate here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 30, 2018 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news

Immunotherapy Clinical Trial Aims for Mesothelioma Cure
Medical oncologist Dr. Bernardo Goulart at the Seattle Cancer Care Alliance (SCCA) believes his latest clinical trial might be the most curative approach to treatment of pleural mesothelioma. He also believes it could work. Goulart is the principal investigator at SCCA, which has embraced a novel clinical trial that combines the immunotherapy drug Tecentriq (atezolizumab) with a multimodal regimen of chemotherapy, surgery and radiation. “The trial design is very intense, requiring multidisciplinary involvement,” Goulart told Asbestos.com. “I think it could provide insight into the next step of research th...
Source: Asbestos and Mesothelioma News - July 25, 2018 Category: Environmental Health Authors: Matt Mauney Source Type: news

Only 16% of those most at risk of bladder and kidney cancer check for this one vital sign
Blood in urine is a key symptom of kidney cancer.07/19/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - July 23, 2018 Category: Urology & Nephrology Source Type: news

Bladder cancer symptoms: Watch out for this shocking sign only 16 per cent check for
BLADDER cancer symptoms are triggered when its cells start dividing uncontrollably. Britons aren ’t always checking for signs. Watch out for this symptom of bladder and kidney cancer that only 16 per cent of Britons check for. (Source: Daily Express - Health)
Source: Daily Express - Health - July 21, 2018 Category: Consumer Health News Source Type: news

Bladder cancer symptoms: Check for this colour urine when you go to the toilet
BLADDER cancer symptoms are almost all linked to urination and your toilet habits. The most common sign if blood in the urine, but this can appear in a variety of colours. Public Health England has now launched a new campaign to urge people to check their pee. (Source: Daily Express - Health)
Source: Daily Express - Health - July 19, 2018 Category: Consumer Health News Source Type: news

Photodynamic Diagnosis of Bladder Cancer With Oral 5-ALA Is Feasible, Safe
TURBT with fluorescent light source using oral 5-ALA is well tolerated in non –muscle-invasive bladder cancer. (Source: CancerNetwork)
Source: CancerNetwork - July 18, 2018 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news

Poorer Survival, Higher Costs With Trimodal Therapy in Bladder Cancer
Patients with muscle-invasive bladder cancer who underwent trimodal therapy had significantly poorer survival than those who underwent radical cystectomy alone. (Source: CancerNetwork)
Source: CancerNetwork - July 18, 2018 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news

Officials investigating spike in cancers on Long Island  
New York health officials are investigating after significant rates of leukemia, bladder, lung and thyroid cancers were found in three Long Island counties - 16 percent of all cases in New York state. (Source: the Mail online | Health)
Source: the Mail online | Health - July 17, 2018 Category: Consumer Health News Source Type: news

Be clear on cancer: blood in pee campaign
Public Health England will re-run the be clear on cancer: blood in pee campaign from 19 July to 23 September 2018. The aim is to raise public awareness of visible haematuria, a key symptom of bladder and kidney cancer and encourage those who notice this symptom to see their GP without delay. (Source: NHS Networks)
Source: NHS Networks - July 16, 2018 Category: UK Health Source Type: news

Woman's urine infection turned out to be bladder cancer
Julie Morawaka, 55, a bank manager from Great Wakering in Essex, had her bladder, womb and part of her vagina removed after what she thought was a urine infection turned out to be bladder cancer. (Source: the Mail online | Health)
Source: the Mail online | Health - July 12, 2018 Category: Consumer Health News Source Type: news

Targeting tumor-associated acidity in cancer immunotherapy
Checkpoint inhibitors, such as cytotoxic T-lymphocyte-associated protein-4 (CTLA-4) and programmed cell death-1 (PD-1) monoclonal antibodies have changed profoundly the treatment of melanoma, renal cell carcinoma, non-small cell lung cancer, Hodgkin lymphoma, and bladder cancer. Currently, they are tested in various tumor entities as monotherapy or in combination with chemotherapies or targeted therapies. However, only a subgroup of patients benefit from checkpoint blockade (combinations).07/11/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - July 11, 2018 Category: Urology & Nephrology Source Type: news

Robotic surgery as effective as open surgery for bladder cancer
(Loyola University Health System) Robotic surgery is as effective as traditional open surgery in treating bladder cancer, according to a landmark study published in the journal Lancet. Three Loyola Medicine urologists are co-authors of the study. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 11, 2018 Category: International Medicine & Public Health Source Type: news

Discovery of new biomarker could provide personalized treatment options for bladder cancer
(The Mount Sinai Hospital / Mount Sinai School of Medicine) A research team at Mount Sinai has identified two microRNA activity-based biomarkers that can provide insights regarding which patients with p53-like bladder cancer may have a better versus worse prognosis. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 2, 2018 Category: Biology Source Type: news

Study: Simpler test cuts costs, overtreatment for bladder cancer patients
For patients with bladder cancer, a simple test can cut down on care costs, overtreatment and side effects, according to a study. (Source: Health News - UPI.com)
Source: Health News - UPI.com - June 28, 2018 Category: Consumer Health News Source Type: news

For some bladder cancer patients, simple test could reduce over-treatment, ease high cost
(Georgetown University Medical Center) Georgetown-led investigators have found that a fairly simple test significantly improves the identification of bladder tumors that will likely become invasive. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 28, 2018 Category: Cancer & Oncology Source Type: news

Worse OS, Higher Costs Tied to Trimodal Tx for Bladder Cancer
(MedPage Today) -- Bladder-sparing approach would cost $335 million more annually (Source: MedPage Today Surgery)
Source: MedPage Today Surgery - June 27, 2018 Category: Surgery Source Type: news

Metabolomic Analysis May Provide Non-Invasive Bladder Cancer Surveillance
A new study identified several metabolites and metabolic indicators as potential biomarkers for recurrence risk in non –muscle-invasive bladder cancer. (Source: CancerNetwork)
Source: CancerNetwork - June 23, 2018 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news

Study: No difference in complications, survival rate between robot-assisted and open bladder surgeries
A seven-year study comparing outcomes from robotic and open cystectomy procedures showed no statistically significant difference in complications or survival rate between the two methods. The randomized open versus robotic cystectomy study, known as the Razor trial, is touted as the first comprehensive study to compare outcomes between robotic and traditional open surgeries in any organ. Results from the trial were recently published in the journal The Lancet. “We have done more than 4 million surgeries with the robotic approach since the device came into existence, and on average we do close to a million robotic sur...
Source: Mass Device - June 22, 2018 Category: Medical Devices Authors: Fink Densford Tags: Clinical Trials Robotics Surgical Source Type: news

Israel's UroGen to start mid-stage bladder cancer trial
RAANANA, Israel (Reuters) - Israel's UroGen Pharma plans to begin a mid-stage trial of its treatment for bladder cancer patients in August, after positive interim results last month from an advanced trial of a treatment for upper urinary tract cancer. (Source: Reuters: Health)
Source: Reuters: Health - June 21, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

First major study comparing robotic to open surgery published in The Lancet
(University of Miami) The first comprehensive study comparing the outcomes of robotic surgery to those of traditional open surgery in any organ has found that the surgeries are equally effective in treating bladder cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 21, 2018 Category: Cancer & Oncology Source Type: news

Gender Difference in Survival Seen After Radical Cystectomy
WEDNESDAY, June 20, 2018 -- Compared with males, females who undergo radical cystectomy for bladder cancer have worse disease-free, cancer-specific, and overall survival, according to a review published in the July issue of The Journal of... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 20, 2018 Category: Pharmaceuticals Source Type: news

GenomeDx Biosciences and Pathnostics Launch Enhanced Version of Guidance Tests
Now Offering Both Phenotype and Genotype Testing for Antibiotic Resistance SAN DIEGO and Irvine, Calif., June 19, 2018 -- (Healthcare Sales & Marketing Network) -- GenomeDx Biosciences and Pathnostics today announced the launch of the next generation G... Diagnostics, Oncology, Product Launch GenomeDx Biosciences, Pathnostics, prostate cancer, bladder cancer (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - June 19, 2018 Category: Pharmaceuticals Source Type: news

Lower Survival With Checkpoint Inhibitors in Bladder Cancer Lower Survival With Checkpoint Inhibitors in Bladder Cancer
Agencies in both the United States and Europe have warned about a decreased survival in patients treated with checkpoint inhibitors compared with those receiving chemotherapy.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 12, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Could Mesothelioma Chemotherapy Ever Be Obsolete?
Oncologist Dr. Arek Dudek at Regions Hospital Cancer Care Center in St. Paul, Minnesota, believes his clinical trial involving a novel immunotherapy combination could change the way doctors treat pleural mesothelioma. Dudek is opening the only Phase II trial evaluating the combination of nivalumab (Opdivo) and ramucirumab (Cyramza) for previously treated mesothelioma patients. “This strategy – if successful, like we think it will be – could make treatment with chemotherapy obsolete,” Dudek told Asbestos.com. “People can be really excited about this one.” He based his optimism on the pote...
Source: Asbestos and Mesothelioma News - June 1, 2018 Category: Environmental Health Authors: Walter Pacheco Source Type: news

Medical News Today: Sandalwood scent may tackle bladder cancer tumors
New research has identified olfactory receptors in cancerous bladder tissue. These could make good biomarkers, and they may also help to improve therapy. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 1, 2018 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news

EMA recommends restrictions on Merck, Roche immunotherapies
ZURICH (Reuters) - The European Medicines Agency on Friday recommended restricting use of two immunotherapies, one from Roche and the other from Merck, in initial bladder cancer treatment, saying they may not work as well as chemotherapy in some patients. (Source: Reuters: Health)
Source: Reuters: Health - June 1, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Medical News Today: What to expect with bladder removal surgery
Bladder removal surgery or cystectomy is a procedure to remove the urinary bladder. It is commonly used to treat bladder cancer or other pelvic tumors. A person should go into surgery knowing what to expect, during and after the procedure, including recovery times, outlook, and the effect on quality of life afterward. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 31, 2018 Category: Consumer Health News Tags: Urology / Nephrology Source Type: news

Prostate cancer warning - add this 18p fruit to your diet to slash your risk
PROSTATE cancer symptoms include passing more urine than normal, rushing to the toilet, and feeling like your bladder is never truly empty. But, adding this cheap fruit to your diet could lower your risk of the deadly tumour, which is the most commonly diagnosed male cancer in the UK. (Source: Daily Express - Health)
Source: Daily Express - Health - May 30, 2018 Category: Consumer Health News Source Type: news

Bladder cancer symptoms: Seeing THIS in your urine could be a sign of the dangerous cancer
BLADDER cancer symptoms appear when a tumour develops in the lining of this organ. You are more at risk of bladder cancer if you ’re a smoker, or have been exposed to certain chemicals through your profession, such as in the plastics, paints and textiles industries. Finding this in your urine could be a sign of the dangerous cancer. (Source: Daily Express - Health)
Source: Daily Express - Health - May 30, 2018 Category: Consumer Health News Source Type: news

Bladder cancer symptoms: Finding THIS in your urine could be a sign you have the cancer
BLADDER cancer symptoms appear when a tumour develops in the lining of this organ. You are more at risk of bladder cancer if you ’re a smoker, or have been exposed to certain chemicals through your profession, such as in the plastics, paints and textiles industries. Finding this in your urine could be a sign of the dangerous cancer. (Source: Daily Express - Health)
Source: Daily Express - Health - May 30, 2018 Category: Consumer Health News Source Type: news

Urologists Practice Spotting Tumors With Virtual Reality Technology
BOSTON (CBS) – Virtual reality is being used in healthcare more, and a local company is using the technology to help doctors identify hard-to-see tumors in the bladder. Almost 80,000 Americans are diagnosed with bladder cancer every year. To find bladder tumors, a urologist looks directly at the inside of the bladder using a cystoscope, a small tube with a camera and light attached. Cystoscopes are equipped with technology called narrow band imaging. (WBZ-TV) Some tumors are harder to find. But to make it easier, many cystoscopes are equipped with technology called narrow band imaging (NBI). “What NBI does is i...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - May 29, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Seen On WBZ-TV Syndicated Local Dr. Mallika Marshall HealthWatch Local TV Virtual Reality Source Type: news

Olfactory receptor as therapeutic target in bladder cancer
(Ruhr-University Bochum) Researchers from Bochum have detected an olfactory receptor in the human bladder that might prove useful for bladder cancer therapy and diagnosis. Using cell culture studies, the team headed by Professor Dr. Hanns Hatt and Dr. Lea Weber demonstrated that the receptor occurs more frequently in bladder cancer tissue than in healthy bladder tissue. Accordingly, significant higher amounts of the receptor could be found in the urine samples of patients. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 29, 2018 Category: Cancer & Oncology Source Type: news

CR Rate of 30% With Agent for High-Risk Bladder Cancer CR Rate of 30% With Agent for High-Risk Bladder Cancer
With a complete response (CR) rate of 30%, the experimental agent CG0070 is in a race to be the first drug since 1998 for the treatment of BCG-unresponsive bladder cancer.Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 25, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Living With Cancer: Understanding bladder cancer
Bladder cancer? Bladder cancer is one of the most common cancers, affecting approximately 68,000 adults in the U.S. each year. Bladder cancer occurs more frequently in men and usually affects older adults. May is Bladder Cancer Awareness Month, which makes it a good time to learn more about the symptoms, causes, risk factors and treatment [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - May 25, 2018 Category: Databases & Libraries Source Type: news

Staff shortages a factor in case where patient died due to delays
Staffing shortages at a hospital run by Barking, Havering and Redbridge University Hospitals NHS Trust were a factor in the case of a grandmother whose “painful” death from bladder cancer could have been avoided, a report by the health service ombudsman has revealed. (Source: Nursing Times)
Source: Nursing Times - May 22, 2018 Category: Nursing Source Type: news