The Not-Quite Annual ASCO Round-Up - 2018 edition

by Drew RosielleTheAmerican Society of Clinical Oncology annual meeting, besides being a feast for the pharmaceutical business news pages (google'ASCO'and most of the hits will be about how announcement X affected drug company Y's stock), is also one of the premiere platforms for publishing original palliative-oncology research. So every year I try to at least scan the abstracts to see what's happening, and I figure I might as well blog about it. It's tough to analyze abstracts, so I'll mostly just be summarizing ones that I think will be of interest to hospice and palliative care folks. I imagine I've missed some good ones, please leave a link in the comments if I have! My major observations on this year's abstracts is that there was very little about symptom management compared to years past, except for neuropathies.(Past ASCO reviews here -2008,2017 - Ed.)Fatigue/NutritionA negative phase 2 study of a walking intervention for fatigue in patients with breast cancerA look at 10-year trends in TPN use in cancer patients (use is slightly declining, as are costs, and involvement of palliative care is increasing)Parenteral nutrition once again fails to show any benefit over oral feeding for cancer cachexia (and in fact suggested harm)A nice study looking at the determinants of long-term fatigue in patients with treated ovarian cancerPerhaps the microbiome influences cancer-related fatigue?CommunicationCode status, race, and palliative care invo...
Source: Pallimed: A Hospice and Palliative Medicine Blog - Category: Palliative Care Tags: artificial nutrition ASCO cannabanoid code status conference reviews fatigue hpmglobal marijuana mindfulness mucositis neuropathic oncology pain race rosielle scrambler Source Type: blogs

Related Links:

In this study, we provide the first estimates that leverage variation in SNAP purchasing power across markets to examine effects of SNAP on child health. We link panel data on regional food prices to National Health Interview Survey data and use a fixed effects framework to estimate the relationship between local purchasing power of SNAP and children’s health and health care utilization. We find that lower SNAP purchasing power leads to lower utilization of preventive health care and more days of school missed due to illness. We estimate no effect on parent-reported health status.
Source: Journal of Health Economics - Category: Health Management Source Type: research
Publication date: Available online 14 September 2019Source: Gene Expression PatternsAuthor(s): P. Arya, P.K. Pradhan, Anutosh Paria, R. Sharma, Dev K. Verma, Ravindra, G. Rathore, N. SoodAbstractIndia is the second largest fish producing country in the world with production of 12.6 million tonnes (mt) in 2017–18, and Indian major carps (IMCs) share bulk of this fish production. Catla, Catla catla is the fastest growing species among IMCs. However, the survival rate of catla during larval rearing is normally lower than the other IMCs i.e rohu Labeo rohita, and mrigal Cirrhinus mrigala. Continuous efforts are devoted f...
Source: Gene Expression Patterns - Category: Genetics & Stem Cells Source Type: research
Publication date: November 2019Source: International Journal of Industrial Ergonomics, Volume 74Author(s): Morten Wærsted, Henrik Enquist, Kaj Bo VeierstedAbstractDuring nine months, nineteen hairdressers every second/third month switched the use between a blow dryer with traditional design and one with a new design. The new blow dryer had the possibility to change between two opposite directed air flows. Every second/third month arm inclination angle and upper trapezius muscle activity were measured a whole workday, and during blow-drying in the laboratory. Pronounced upper arm elevation was reduced with the new blo...
Source: International Journal of Industrial Ergonomics - Category: Occupational Health Source Type: research
Source: Journal of Allied Health - Category: Universities & Medical Training Authors: Tags: Research Note Source Type: research
ConclusionGreater awareness of HWWS will lead to earlier detection and is the key to alleviating patient suffering and avoiding potentially severe complications.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
Do any of you have a good method of prescribing home SPG for a migraine abortive? I’ve prescribed lidocaine drops successfully but I’m not sure what I can prescribe for equipment to administer it (dropper, syringes, etc). Thanks!
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pain Medicine Source Type: forums
ConclusionIsometric exercise, patellar strapping, sports taping, eccentric exercise, injections with PRP, ABI, and saline and DN demonstrated a short-term pain relieving and functional improvement effect in subjects with patellar tendinopathy. Longer term follow up on interventions involving eccentric exercise, DN, and injections with PRP, ABI and saline showed sustained pain reduction and improvement in knee function.Level of evidenceLevel 1.
Source: Journal of Science and Medicine in Sport - Category: Sports Medicine Source Type: research
Publication date: Available online 14 September 2019Source: Journal of Advanced ResearchAuthor(s): Simone Kumstel, Praveen Vasudevan, Rupert Palme, Xianbin Zhang, Edgar Heinz Uwe Wendt, Robert David, Brigitte Vollmar, Dietmar ZechnerAbstractProspective severity assessment is legally required in many countries to ensure high-quality research along with high welfare standards for laboratory animals. Mice and rats, the most common laboratory species, are prey animals that usually suppress signs of pain and suffering. Therefore, highly sensitive readout parameters are necessary to adequately quantify distress. The present stud...
Source: Journal of Advanced Research - Category: Research Source Type: research
Authors: Shackleton C, Evans R, Shamley D, West S, Albertus Y Abstract OBJECTIVES: To evaluate the effectiveness of over-ground robotic locomotor training in individuals with spinal cord injuries with regard to walking performance, cardiovascular demands, secondary health complications and user-satisfaction. DATA SOURCES: PubMed, Cochrane, Web of Science, Scopus, EBSCOhost and Engineering Village. STUDY SELECTION: Trials in which robotic locomotor training was used for a minimum of 3 participants with spinal cord injury. DATA EXTRACTION: Independent extraction of data by 2 reviewers using a pre-establis...
Source: Journal of Rehabilitation Medicine - Category: Rehabilitation Tags: J Rehabil Med Source Type: research
Authors: Reinert T, Coelho GP, Mandelli J, Zimermann E, Zaffaroni F, Bines J, Barrios CH, Graudenz MS Abstract Mutations in the ESR1 gene (ESR1m) are important mechanisms of resistance to endocrine therapy in estrogen receptor-positive advanced breast cancer and have been recognized as a prognostic and predictive biomarker as well as a potential therapeutic target. However, the prevalence of ESR1m in real-world patients has not been adequately described. Therefore, we sought to evaluate the prevalence of ESR1m in metastatic samples from Brazilian patients with estrogen receptor-positive (ER+) advanced breast cancer...
Source: Journal of Oncology - Category: Cancer & Oncology Tags: J Oncol Source Type: research
More News: African Health | Blogging | Brain | Breast Cancer | Cancer | Cancer & Oncology | Childhood Cancer | Chronic Pain | Conferences | Databases & Libraries | Head and Neck Cancer | Hematology | Managed Care | Medicare | National Institute for Health and Clinical Excelle | Neurology | Nutrition | Omega 6 | Oral Cancer | Ovarian Cancer | Ovaries | Pain | Pain Management | Palliative | Palliative Care | Pancreas | Pancreatic Cancer | Parenteral Nutrition | PET Scan | Stem Cell Therapy | Stem Cells | Study | Training | Transplants | Universities & Medical Training | University of Minnesota