Essential oils from Artemisia species inhibit biofilm formation and the virulence of Escherichia coli EPEC 2348/69.
Abstract Enteropathogenic Escherichia coli E2346/69 (EPEC) has caused foodborne outbreaks worldwide and the bacterium forms antimicrobial-tolerant biofilms. The anti-biofilm formation of various components of essential oils extracted from selected medicinal plants were investigated and tested on EPEC and wild strains of E. coli. Oils extracted from the family Asteraceae and their major common constituents at 0.031 and 0.062% (V/v) were found to significantly inhibit biofilm formation without affecting the growth of planktonic cells. In addition, three plants belonging to this family (Artemisia herba alba, ...
Source: Biofouling - February 15, 2021 Category: Molecular Biology Authors: Mathlouthi A, Saadaoui N, Pennacchietti E, De Biase D, Ben-Attia M Tags: Biofouling Source Type: research

In vitro and in vivo biological activities of azulene derivatives with potential applications in medicine
AbstractAzulene is an aromatic hydrocarbon that possesses a unique chemical structure and interesting biological properties. Azulene derivatives, including guaiazulene or chamazulene, occur in nature as components of many plants and mushrooms, such asMatricaria chamomilla,Artemisia absinthium,Achillea millefolium, andLactarius indigo. Due to physicochemical properties, azulene and its derivatives have found many potential applications in technology, especially in optoelectronic devices. In medicine, the ingredients of these plants have been widely used for hundreds of years in antiallergic, antibacterial, and anti-inflamma...
Source: Medicinal Chemistry Research - January 30, 2021 Category: Chemistry Source Type: research

High-defined quantitative snapshots of the ganglioside lipidome using high resolution ion mobility SLIM assisted shotgun lipidomics.
Abstract Defects in sphingolipid metabolism have emerged as a common link across neurodegenerative disorders, and a deeper understanding of the lipid content in preclinical models and patient specimens offers opportunities for development of new therapeutic targets and biomarkers. Sphingolipid metabolic pathways include the formation of glycosphingolipid species that branch into staggeringly complex structural heterogeneity within the globoside and ganglioside sub-lipidomes. Characterization of these sub-lipidomes has typically relied on liquid chromatography-mass spectrometry-based (LC-MS) approaches, but...
Source: Analytica Chimica Acta - January 21, 2021 Category: Chemistry Authors: Wormwood Moser KL, Van Aken G, DeBord D, Hatcher NG, Maxon L, Sherman M, Yao L, Ekroos K Tags: Anal Chim Acta Source Type: research

Dense Breast Notification Laws’ Association With Outcomes in the US Population: A Cross-Sectional Study
Publication date: Available online 25 December 2020Source: Journal of the American College of RadiologyAuthor(s): Nancy R. Kressin, Tracy A. Battaglia, Jolie B. Wormwood, Priscilla J. Slanetz, Christine M. Gunn (Source: Journal of the American College of Radiology)
Source: Journal of the American College of Radiology - December 25, 2020 Category: Radiology Source Type: research

Dense Breast Notification Laws ’ Association With Outcomes in the US Population: A Cross-Sectional Study
We examined self-reported receipt of personal breast density information, breast density discussions with providers, knowledge about density’s masking effect, and association with incre ased breast cancer risk by state legislation status and women’s sociodemographic characteristics. (Source: Journal of the American College of Radiology : JACR)
Source: Journal of the American College of Radiology : JACR - December 24, 2020 Category: Radiology Authors: Nancy R. Kressin, Tracy A. Battaglia, Jolie B. Wormwood, Priscilla J. Slanetz, Christine M. Gunn Tags: Original Article Source Type: research

Sparrows use a medicinal herb to defend against parasites and increase offspring condition.
Abstract The incorporation of aromatic plants into nests by birds is suspected to constitute an example of preventative medicine use, whereby the phytochemical compounds within plants reduce infestation by parasites and increase offspring condition [1,2]. In China, russet sparrows (Passer cinnamomeus) incorporate wormwood (Artemisia verlotorum) leaves into their nests around the same time that local people hang wormwood from their doors as a traditional custom during the Dragon Boat Festival. The belief that this behaviour confers protection against ill health [3] is supported by the description of anti-pa...
Source: Current Biology - December 7, 2020 Category: Biology Authors: Yang C, Ye P, Huo J, Møller AP, Liang W, Feeney WE Tags: Curr Biol Source Type: research

Methanolic extract of Artemisia absinthium prompts apoptosis, enhancing expression of Bax/Bcl-2 ratio, cell cycle arrest, caspase-3 activation and mitochondrial membrane potential destruction in human colorectal cancer HCT-116 cells.
This study aims to assess the anticancer activity of the methanolic extract of A. absinthium (MEAA) against human colorectal cancer HCT-116 cell line. The cytotoxic effects of MEAA on HCT-116 cells was evaluated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium (MTT) assay. The expression levels of BAX and BCL-2 in HCT-116 cell line were examined by qRT-PCR. Annexin V/PI-flow cytometry technique was used to detect the cell cycle and apoptosis. MMP was predicted by Rhodamine 123 staining, and caspase 3 activity was analyzed by ELISA. Western blot method was performed to detect the expression level of BAX, Bcl-2 and Ca...
Source: Molecular Biology Reports - November 3, 2020 Category: Molecular Biology Authors: Nazeri M, Mirzaie-Asl A, Saidijam M, Moradi M Tags: Mol Biol Rep Source Type: research

Chemical Composition and Antimicrobial Activity of the Essential Oils of Artemisia absinthium, Artemisia scoparia, and Artemisia sieberi Grown in Saudi Arabia
Publication date: Available online 8 October 2020Source: Arabian Journal of ChemistryAuthor(s): Hanan Y. Aati, Shagufta Perveen, Raha Orfali, Areej M. Al-Taweel, Sultan Yahya, Juergen Wanner, Afsar Khan, Rashad Mehmood (Source: Arabian Journal of Chemistry)
Source: Arabian Journal of Chemistry - October 9, 2020 Category: Chemistry Source Type: research

Chemotypic variation of non-volatile constituents of Artemisia afra (African wormwood) from South Africa.
Abstract Artemisia afra, (African wormwood) is a popular medicinal plant of southern Africa and is an excellent candidate for commercialisation. This current study was aimed at exploring the phytochemistry and chemical variation of non-volatile compounds within wild populations of A, afra, and developing chromatographic quality control protocols for raw materials based on the identification of marker compounds. Chromatographic data, from samples representing 12 distinct populations were obtained using liquid chromatography-mass spectrometry. An untargeted chemometric approach revealed three clusters. Marke...
Source: Fitoterapia - October 8, 2020 Category: Biochemistry Authors: Sotenjwa VZ, Chen W, G L Veale C, Anokwuru CP, Tankeu S, Combrinck S, Kamatou GPP, Viljoen AM Tags: Fitoterapia Source Type: research

Bioactive principles and potentiality of hot methanolic extract of the leaves from Artemisia absinthium L "in vitro cytotoxicity against human MCF-7 breast cancer cells, antibacterial study and wound healing activity".
CONCLUSION: The study suggested that novel anticancer, antibacterial and immune modulatory molecules can be developed from the leaves of Artemisia absinthium L. PMID: 32988347 [PubMed - as supplied by publisher] (Source: Current Pharmaceutical Biotechnology)
Source: Current Pharmaceutical Biotechnology - September 27, 2020 Category: Biotechnology Authors: Sultan MH, Zuwaiel AA, Moni SS, Alshahrani S, Alqahtani SS, Madkhali O, Elmobark ME Tags: Curr Pharm Biotechnol Source Type: research

Cytotoxic potential of Artemisia absinthium extract loaded polymeric nanoparticles against breast cancer cells: Insight into the protein targets
Publication date: 30 August 2020Source: International Journal of Pharmaceutics, Volume 586Author(s): Mohd Mughees, Saima Wajid, Mohd Samim (Source: International Journal of Pharmaceutics)
Source: International Journal of Pharmaceutics - July 2, 2020 Category: Drugs & Pharmacology Source Type: research

Evaluation of Two New Methods for DNA Extraction of "Legal High" Plant Species.
Abstract A quick, simple, and high-yield nucleic acid isolation process is crucial for high-quality DNA analysis. The ability of the MicroGEM PDQeX phytoGEM system and Omega Bio-tek E.Z.N.A.® Plant DS Mini kit to extract PCR-ready DNA was evaluated by extracting the forensically relevant "legal high" plant species: Ipomoea purpurea, Artemisia absinthium, Mitragyna speciosa, Datura stramonium, and Papaver somniferum. The plant material was pulverized, processed using the manufacturer's plant protocol for the PDQeX Nucleic Acid Extraction or the manufacturer's protocol for the Omega extraction, quantified u...
Source: Journal of Forensic Sciences - June 14, 2020 Category: Forensic Medicine Authors: Ryan AL, O'Hern CP, Elkins KM Tags: J Forensic Sci Source Type: research

Effect of dry medicinal plants (wormwood, chamomile, fumitory and mallow) on in vitro ruminal antioxidant capacity and fermentation patterns of sheep
The objective of this study was to determine the effect of dry medicinal plants (wormwood, chamomile, fumitory and mallow) and dietary substrates containing a mix of the plants on the end products of in vitro ruminal and intestinal fermentation, rumen protozoan population and ruminal antioxidant capacity of sheep. The experiment consisted of fermentations with the four plants used individually as the sole substrate and fermentation of a mix of medicinal plants (Plants): meadow hay:barley grain (MH:B), 700/300 w/w and Plants:MH:B, 100/600/300 w/w/w. The experiment was conducted using the in vitro gas production technique (I...
Source: Journal of Animal Physiology and Animal Nutrition - March 24, 2020 Category: Zoology Authors: Daniel Petri č, Dominika Mravčáková, Katarína Kucková, Klaudia Čobanová, Svetlana Kišidayová, Adam Cieslak, Sylwester Ślusarczyk, Zora Váradyová Tags: ORIGINAL ARTICLE Source Type: research

The Effect of Auxin and Auxin-Producing Bacteria on the Growth, Essential Oil Yield, and Composition in Medicinal and Aromatic Plants.
Abstract Aromatic plants had been used since ancient times for their preservative and medicinal properties, and to impart aroma and flavor to food. Also their secondary metabolites are economically important as drugs, flavor and fragrances, pharmaceuticals, agrochemicals, dye, and pigments, pesticides, cosmetics, food additives, other industrially biochemical, and also play a major role in the adaptation of plants to their environment. Indole acetıc acid-producing rhizobacteria inoculations increase in stomatal density and level of secondary metabolite and have a synergistic effect on monoterpene biosynt...
Source: Current Microbiology - February 19, 2020 Category: Microbiology Authors: Çakmakçı R, Mosber G, Milton AH, Alatürk F, Ali B Tags: Curr Microbiol Source Type: research