To what extent are medicinal plants shared between country home gardens and urban ones? A case study from Misiones, Argentina.
Conclusion In this changing context where mobility and migrations constitute everyday life, medicinal plants in home gardens are part of local healthcare sovereignty. PMID: 26857000 [PubMed - as supplied by publisher] (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - February 16, 2016 Category: Drugs & Pharmacology Tags: Pharm Biol Source Type: research

What the ancient Greeks and Romans knew (and did not know) about seasickness
Conclusion: The triggers, symptoms, and preventive measures of seasickness were well-known in antiquity. The implications for transport of troops and military actions were repeatedly described, e.g., by Livius and Caesar. At that time, the pathophysiologic mechanism was explained by the humoral theory of Empedokles and Aristoteles. Seneca Minor localized the bodily symptoms in various organs such as stomach, gullet, and esophagus, and also attributed them to an imbalance of bile. Recommended medication included ingestion of the plant white hellebore, a violent gastrointestinal poison. This remedy contains various alkaloids...
Source: Neurology - February 8, 2016 Category: Neurology Authors: Huppert, D., Oldelehr, H., Krammling, B., Benson, J., Brandt, T. Tags: Clinical neurology history, All Neuro-ophthalmology, All Neurotology, Vertigo, All clinical neurophysiology HISTORICAL NEUROLOGY Source Type: research

Prefrontal Neurons Encode Actions and Outcomes in Conjunction with Spatial Location in Rats Performing a Dynamic Delayed Non-Match to Position Task
by Kristen D. Onos, Miranda J. Francoeur, Benjamin A. Wormwood, Rikki L. A. Miller, Brett M. Gibson, Robert G. Mair To respond adaptively to change organisms must utilize information about recent events and environmental context to select actions that are likely to produce favorable outcomes. We developed a dynamic delayed nonmatching to position task to study the influence of spatial context on event-related activity of medial prefrontal cortex neurons during reinforcement-guided decision-making. We found neurons with responses related to preparation, movement, lever press responses, reinforcement, and memory delays. Com...
Source: PLoS One - February 5, 2016 Category: Biomedical Science Authors: Kristen D. Onos et al. Source Type: research

Antibacterial and Antioxidant Activity of Traditional Medicinal Plants from the Balkan Peninsula
Publication date: Available online 7 January 2016 Source:NJAS - Wageningen Journal of Life Sciences Author(s): Nemanja Stanković, Tatjana Mihajilov-Krstev, Bojan Zlatković, Vesna Stankov-Jovanović, Violeta Mitić, Jovana Jović, Ljiljana Čomić, Branislava Kocić, Nirit Bernstein Negative effects of available antibiotics and the constant development of bacterial resistance motivate a search for new antimicrobial agents. Aromatics plants have traditionally been used as antibacterial agents and are well accepted today as a source of antioxidants. The present study evaluated the antibacterial activit...
Source: NJAS Wageningen Journal of Life Sciences - January 12, 2016 Category: Biology Source Type: research

Treatment of organic livestock with medicinal plants: a systematic review of European ethnoveterinary research.
CONCLUSIONS: In general, EuEVM provides interesting treatment approaches for gastrointestinal and dermatological disorders as well as parasitosis. Findings regarding disorders of female genital or respiratory tract are less consistent. Nevertheless, EuEVM offers a solid basis for stimulating research in veterinary phytotherapy in Europe with a perspective to solve animal health problems in organic or even nonorganic ruminant production. PMID: 25592949 [PubMed - in process] (Source: Forschende Komplementarmedizin)
Source: Forschende Komplementarmedizin - December 20, 2015 Category: Complementary Medicine Tags: Forsch Komplementmed Source Type: research

The determination of α- and β-thujone in human serum - simple analysis of absinthe congener substance
Absinthe is a strong spirit beverage, a mostly green colored, containing besides alcohol (main component), alcoholic macerate of wormwood (Artemisia absinthium L.) and other plants such as star anise (Illicium verum L.), fennel seed (Feoniculum vulgare L.) and hyssop (Hyssopus officinalis L.) [1,2]. In the late 19th century, absinthe, in the meantime called “green fairy” (“fée verte”), was the most popular spirit drink in Europe [3,4], achieving great recognition among artist and writers. Primarily due to its biomedical active chemical, thujone, the primary constituent of essential oils derived from a variety of p...
Source: Forensic Science International - December 19, 2015 Category: Forensic Medicine Authors: Michal P. Dybowski, Andrzej L. Dawidowicz Source Type: research

The determination of α- and β-thujone in human serum – Simple analysis of absinthe congener substance
Absinthe is a strong spirit beverage, a mostly green colored, containing besides alcohol (main component), alcoholic macerate of wormwood (Artemisia absinthium L.) and other plants such as star anise (Illicium verum L.), fennel seed (Feoniculum vulgare L.) and hyssop (Hyssopus officinalis L.) [1,2]. In the late 19th century, absinthe, in the meantime called “green fairy” (“fée verte”), was the most popular spirit drink in Europe [3,4], achieving great recognition among artist and writers. Primarily due to its biomedical active chemical, thujone, the primary constituent of essential oils derived from a variety of p...
Source: Forensic Science International - December 19, 2015 Category: Forensic Medicine Authors: Michal P. Dybowski, Andrzej L. Dawidowicz Source Type: research

Our experience with atopy patch tests with aeroallergens.
CONCLUSION: For atopy patch testing with aeroallergens the concentration of 1 x skin prick tests is low to confirme the eczematic reaction in patients suffering from allergy to inhallant allergens. PMID: 23909049 [PubMed - indexed for MEDLINE] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - December 12, 2015 Category: Journals (General) Tags: Acta Medica (Hradec Kralove) Source Type: research

In vitro antimicrobial activity of Romanian medicinal plants hydroalcoholic extracts on planktonic and adhered cells.
Authors: Stanciuc AM, Gaspar A, Moldovan L, Saviuc C, Popa M, Măruţescu L Abstract The aim of this study was to assess the antibacterial and antifungal potential of some Romanian medicinal plants, arnica--Arnica montana, wormwood--Artemisia absinthium and nettle--Urtica dioica. In order to perform this antimicrobial screening, we obtained the vegetal extracts and we tested them on a series of Gram-positive and Gram-negative bacteria, and also against two fungal strains. The vegetal extracts showed antimicrobial activity preferentially directed against the planktonic fungal and bacterial growth, while the...
Source: Roumanian Archives of Microbiology and Immunology - December 12, 2015 Category: Microbiology Tags: Roum Arch Microbiol Immunol Source Type: research

China's Tu Youyou, Nobel Laureate in Medicine 2015, and Relationships with the TCM Research Center Graz at the Medical University
For the first time in history, the Nobel Prize in Medicine 2015 was awarded to a researcher who is specialized in traditional Chinese medicine. The Chinese Tu Youyou received this highest award in medicine for her excellent work in malaria research. Tu Youyou and her team found out that artemisinin, the active ingredient of the medicinal herb ‘sweet wormwood', represents an effective malaria therapy. In the following article, the research that led to this Nobel Prize is introduced. In addition, the insidious tropical disease malaria will be explained briefly. Results of the research on moxibustion using Artemisia are als...
Source: Integrative Medicine International - December 11, 2015 Category: Complementary Medicine Source Type: research

Enhancement of CD3AK cell proliferation and killing ability by α-Thujone.
Abstract Thujone is a monoterpene ketone natural substance found mainly in wormwood and sage. Previous studies have shown that Thujone has various pharmacological effects, such as anti-tumor, analgesic, and insecticide. The effect of α-Thujone to human immune cells is still unknown. Our study focuses on investigating the effects and mechanism of α-Thujone to CD3AK (anti- CD3 antibody induced activated killer) cells proliferation and cytotoxicity to colon cancer cell lines. With cell proliferation and FCM assay, it is found that α-Thujone could significantly enhance CD3AK cell proliferation and expressio...
Source: International Immunopharmacology - December 1, 2015 Category: Allergy & Immunology Authors: Zhou Y, Liu JQ, Zhou ZH, Lv XT, Chen YQ, Sun LQ, Chen FX Tags: Int Immunopharmacol Source Type: research

Reversal of carbon tetrachloride-induced hepatic injury by aqueous extract of Artemisia absinthium in Sprague-Dawley rats.
Authors: Saxena M, Shukla S Abstract In the present study, we evaluated the protective activity of an aqueous extract of Artemisia absinthium against CCl4-induced hepatic damage in rats. The protective activity of this extract at three doses (2.5, 5, and 10 ml/ kg, once orally) against CCl4-induced oxidative damage (1.5 ml/kg, once intraperitoneally) in rats was analyzed. Various blood and tissue biochemical studies were performed, and the administration of the toxicant significantly altered blood biochemical variables. Hepatic lipid peroxidation (LPO) was significantly elevated, whereas glutathione (GSH) ...
Source: Journal of Environmental Pathology, Toxicology and Oncology - November 20, 2015 Category: Environmental Health Tags: J Environ Pathol Toxicol Oncol Source Type: research

T‐shaped trichome‐specific expression of monoterpene synthase ADH2 using promoter–β‐GUS fusion in transgenic Artemisia annua L.
In this study, the ADH2 promoter was cloned by the genome walking method. A number of putative cis‐acting elements were predicted in promoter region, suggesting that the ADH2 is driven by a complex regulation mechanism. ADH2 gene was highly expressed in old leaves, whereas the artemisinin biosynthetic genes were mainly expressed in bud and young leaves. The expression of ADH2 gene increased quickly during leaf development, revealed by qRT‐PCR. GUS expression analysis in different tissues of transgenic A. annua demonstrates that ADH2 expression is exclusively located to T‐shaped trichome, not glandular secretory trich...
Source: Biotechnology and Applied Biochemistry - November 5, 2015 Category: Biochemistry Authors: Xueqing Fu, Pu Shi, Qian Shen, Weimin Jiang, Yueli Tang, Zongyou Lv, Tingxiang Yan, Ling Li, Guofeng Wang, Xiaofen Sun, Kexuan Tang Tags: Original Article Source Type: research

T ‐shaped trichome‐specific expression of monoterpene synthase ADH2 using promoter–β‐GUS fusion in transgenic Artemisia annua L.
In this study, the ADH2 promoter was cloned by the genome walking method. A number of putative cis‐acting elements were predicted in promoter region, suggesting that the ADH2 is driven by a complex regulation mechanism. ADH2 gene was highly expressed in old leaves, whereas the artemisinin biosynthetic genes were mainly expressed in bud and young leaves. The expression of ADH2 gene increased quickly during leaf development, revealed by qRT‐PCR. GUS expression analysis in different tissues of transgenic A. annua demonstrates that ADH2 expression is exclusively located to T‐shaped trichome, not glandular secretory trich...
Source: Biotechnology and Applied Biochemistry - November 4, 2015 Category: Biochemistry Authors: Xueqing Fu, Pu Shi, Qian Shen, Weimin Jiang, Yueli Tang, Zongyou Lv, Tingxiang Yan, Ling Li, Guofeng Wang, Xiaofen Sun, Kexuan Tang Tags: Original Article Source Type: research

Treatment of Mild Gastrointestinal Disorders with a Herbal Combination: Results of a Non‐interventional Study with Gastritol® Liquid
A combination of extracts from chamomile, silverweed, licorice, angelica, blessed thistle and wormwood, Gastritol® Liquid, is registered for the use of indigestion and gastrointestinal spasmodic complaints. To gain data on the experience in practice, a non‐interventional open study was conducted in ambulatory patients including diabetics which were treated for 2 weeks. The efficacy of treatment was assessed by medical examination and evaluation of typical symptoms by patients. A total of 149 patients was enrolled, 90 without and 59 with diabetes. The treatment led to relevant improvements in all symptoms in both study...
Source: Phytotherapy Research - November 2, 2015 Category: Biochemistry Authors: Tankred Wegener, Edgar Heimueller Tags: Research Article Source Type: research