Evaluation of anticancer, antioxidant activity and phenolic compounds of Artemisia absinthium L. Extract.
This study aimed to examine the anti-cancer and antioxidant properties and identify the phenolic content of the methanolic extract obtained from Artemisia absinthium L. (AR) species, which is used as folk-medicine. The antioxidant activity of the extract was investigated using total phenolics, flavonoids, ABTS and CUPRAC methods. Phenolic component analysis of the plant extract was performed by LC-MS/MS. The anti-cancer property of AR extract was investigated on human colon (DLD-1), endometrium (ECC-1) cancer cells and embryonic kidney (HEK-293) cells. Cytotoxic effects were defined with MTT, apoptotic activity with DNA fr...
Source: Cellular and Molecular Biology - March 8, 2018 Category: Molecular Biology Tags: Cell Mol Biol (Noisy-le-grand) Source Type: research
Chemical composition and antifungal activity of plant extracts traditionally used in organic and biodynamic farming.
Abstract
Five plant extracts traditionally used in organic and biodynamic farming for pest control and antifungal (downy mildew) disease management were selected after a farmer survey and analyzed for their chemical composition in LC-PDA-MS-MS and using adapted analytical method from food chemistry for determination of class of component (e.g., protein, sugar, lipids…). Their antifungal activity against Penicillium expansum, Botrytis cinerea, Botrytis allii, brown rot causing agents (Monilinia laxa and Monilinia fructigena), and grape downy mildew (Plasmopara viticola) was examined in vitro. White willow...
Source: Environmental Science and Pollution Research International - March 7, 2018 Category: Environmental Health Authors: Andreu V, Levert A, Amiot A, Cousin A, Aveline N, Bertrand C Tags: Environ Sci Pollut Res Int Source Type: research
83PArtemisia absinthium extract loaded polymeric nanoparticles as the therapeutic remedy for breast cancer
Background: Besides significant progress in the field of cancer therapy, breast cancer remains the major ongoing health problem among the women worldwide because of the side effects of available drugs. This problem can be overcome by loading herbal extract into the polymeric nanoparticles that will aid in site-specific drug delivery and increase in the retention time of drug, thereby improving therapeutic efficacy. (Source: Annals of Oncology)
Source: Annals of Oncology - March 5, 2018 Category: Cancer & Oncology Source Type: research
The desert wormwood (Artemisia herba-alba) – From Arabian folk medicine to a source of green and effective nanoinsecticides against mosquito vectors
Publication date: Available online 11 February 2018 Source:Journal of Photochemistry and Photobiology B: Biology Author(s): Al Thbiani Aziz, Mohammed Ali Alshehri, Chellasamy Panneerselvam, Kadarkarai Murugan, Subrata Trivedi, Jazem A. Mahyoub, Mo'awia Mukhtar Hassan, Filippo Maggi, Stefania Sut, Stefano Dall'Acqua, Angelo Canale, Giovanni Benelli The development of eco-friendly and effective insecticides is crucial for public health worldwide. Herein, we focused on the desert wormwood (Artemisia herba-alba), a plant widely used in Arabian traditional medicine, as a source of green nanoinsecticides against mo...
Source: Journal of Photochemistry and Photobiology B: Biology - February 11, 2018 Category: Speech-Language Pathology Source Type: research
Facial Expression Predictions as Drivers of Social Perception.
Abstract
Emerging perspectives in neuroscience indicate that the brain functions predictively, constantly anticipating sensory input based on past experience. According to these perspectives, prediction signals impact perception, guiding and constraining experience. In a series of six behavioral experiments, we show that predictions about facial expressions drive social perception, deeply influencing how others are evaluated: individuals are judged as more likable and trustworthy when their facial expressions are anticipated, even in the absence of any conscious changes in felt affect. Moreover, the effect...
Source: Journal of Personality and Social Psychology - January 25, 2018 Category: Psychiatry & Psychology Authors: Chanes L, Wormwood JB, Betz N, Barrett LF Tags: J Pers Soc Psychol Source Type: research
Comparative Antitussive Effects of Medicinal Plants and Their Constituents.
Conclusions • These results suggest the therapeutic potential of the studied medicinal plants as antitussive therapies. However, only a few clinical studies have examined the antitussive effects of medicinal plants, and more clinical studies are needed. The underlying mechanisms of the antitussive effects of medicinal plants should be also examined in further studies.
PMID: 29332022 [PubMed - as supplied by publisher] (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - January 15, 2018 Category: Complementary Medicine Authors: Saadat S, Shakeri F, Boskabady MH Tags: Altern Ther Health Med Source Type: research
Evaluation of antioxidant capacity and phenolic content in ethanolic extracts of leaves and flowers of some Asteraceae species.
CONCLUSION: Artemisia absinthium, A. lappa and E. ritro can use as easily accessible source of natural antioxidants and as a possible food supplement or in pharmaceutical industry.
PMID: 29065850 [PubMed - as supplied by publisher] (Source: Recent Patents on Food, Nutrition and Agriculture)
Source: Recent Patents on Food, Nutrition and Agriculture - October 29, 2017 Category: Food Science Tags: Recent Pat Food Nutr Agric Source Type: research
IJERPH, Vol. 14, Pages 1280: The Assessment of Toxic Metals in Plants Used in Cosmetics and Cosmetology
Stojko
Heavy metals polluting the natural environment are absorbed by plants. The use of herbs as components of cosmetics may pose a health risk for humans. The aim of the study was to determine the concentrations of Pb, Cd and Hg in selected species of herbs (horsetail Equisetum arvense, nettle Urtica dioica, St. John’s wort Hypericum perforatum, wormwood Artemisia absinthium, yarrow Achillea millefolium, cottonwood Solidago virgaurea) self-collected from the natural environment in two different locations, and purchased in stores on the territory of Poland. The concentration of the metals studied was: 4.67–23.8 mg...
Source: International Journal of Environmental Research and Public Health - October 24, 2017 Category: Environmental Health Authors: Agnieszka Fischer Barbara Brodziak-Dopiera ła Krzysztof Loska Jerzy Stojko Tags: Article Source Type: research
Artemisinin disrupts androgen responsiveness of human prostate cancer cells by stimulating the 26S proteasome-mediated degradation of the androgen receptor protein
Androgen receptor (AR) expression and activity is highly linked to the development and progression of prostate cancer and is a target of therapeutic strategies for this disease. We investigated whether the antimalarial drug artemisinin, which is a sesquiterpene lactone isolated from the sweet wormwood plant Artemisia annua, could alter AR expression and responsiveness in cultured human prostate cancer cell lines. Artemisinin treatment induced the 26S proteasome-mediated degradation of the receptor protein, without altering AR transcript levels, in androgen-responsive LNCaP prostate cancer cells or PC-3 prostate cancer cell...
Source: Anti-Cancer Drugs - September 16, 2017 Category: Cancer & Oncology Tags: Preclinical Reports Source Type: research
Drug-Herb Interactions in the Elderly Patient with IBD: a Growing Concern
Opinion statementInflammatory bowel disease (IBD), which includes conditions such as Crohn ’s disease and ulcerative colitis, is becoming more prevalent with the elderly being the fastest growing group. Parallel to this, there is an increasing interest in the use of complementary and alternative medicine (CAM). Nearly half of patients with IBD have used CAM at one time. The elderly pati ents, however, are burdened by comorbid conditions, polypharmacy, and altered functional status. With increasing use of complementary and alternative medicine in our elderly patients with IBD, it is vital for the provider to provide couns...
Source: Current Treatment Options in Gastroenterology - September 16, 2017 Category: Gastroenterology Source Type: research
Molecules, Vol. 22, Pages 1473: Medicinal Plants Based Products Tested on Pathogens Isolated from Mastitis Milk
odim Fiț
Bovine mastitis a major disease that is commonly associated with bacterial infection. The common treatment is with antibiotics administered intramammary into infected quarters of the udder. The excessive use of antibiotics leads to multidrug resistance and associated risks for human health. In this context, the search for alternative drugs based on plants has become a priority in livestock medicine. These products have a low manufacturing cost and no reports of antimicrobial resistance to these have been documented. In this context, the main objective of this study was to determine the antimicrobial effect of...
Source: Molecules - September 4, 2017 Category: Chemistry Authors: Claudia Pa șca Liviu M ărghitaș Daniel Dezmirean Otilia Bobi ș Victori ța Bonta Flore Chiril ă Ioana Matei Nicodim Fi ț Tags: Article Source Type: research
Avoiding premature closure and reaching diagnostic accuracy: some key predictive factors
ConclusionsLevel of training (i.e. clinical experience) was not associated with accuracy on this task. As faculty clinicians certainly have more knowledge than their junior counterparts, it is important to identify ways in which cognitive factors can lead to more or less persistence and openness, and to teach clinicians how to overcome tendencies associated with error. (Source: Medical Education)
Source: Medical Education - August 30, 2017 Category: Universities & Medical Training Authors: Edward Krupat, Jolie Wormwood, Richard M Schwartzstein, Jeremy B Richards Tags: Diagnostic Reasoning Source Type: research
Absolute configuration of the ocimene monoterpenoids from Artemisia absinthium.
Abstract
The absolute configuration (AC) of the naturally occurring ocimenes (-)-(3S,5Z)-2,6-dimethyl-2,3-epoxyocta-5,7-diene (1) and (-)-(3S,5Z)-2,6-dimethylocta-5,7-dien-2,3-diol (2), isolated from the essential oils of domesticated specimens of Artemisia absinthium, followed by vibrational circular dichroism (VCD) studies of 1, as well as from the acetonide 3 and the monoacetate 4, both derived from 2, since secondary alcohols are not the best functional groups to be present during VCD studies in solution due to intermolecular associations. The AC follows from comparison of experimental and calculated V...
Source: Chirality - August 25, 2017 Category: Molecular Biology Authors: Julio LF, Burgueño-Tapia E, Díaz CE, Pérez-Hernández N, González-Coloma A, Joseph-Nathan P Tags: Chirality Source Type: research
Kidney toxicity related to herbs and dietary supplements: Online table of case reports. Part 3 of 5 series.
CONCLUSION: This online "DS Toxic Table" provides clinicians, consumers, and manufacturers with a list of herbs that could potentially contribute to kidney injuries.
PMID: 28755953 [PubMed - in process] (Source: Food and Chemical Toxicology)
Source: Food and Chemical Toxicology - August 2, 2017 Category: Food Science Authors: Brown AC Tags: Food Chem Toxicol Source Type: research
Fermentation quality and nutritive value of total mixed ration silages based on desert wormwood (Artemisia desertorum Spreng.) combining with early stage corn
This study aimed to investigate the fermentation quality and nutritive value of total mixed ration (TMR) silages based on desert wormwood (DW) combined with early stage corn (ESC) as forage and determine an optimum formula. Desert wormwood and ESC were harvested, chopped, and mixed with other ingredients according to a formula, packed into laboratory silos at densities of 500–550 g/L, and stored in the dark for 60 days. The DW proportions in the forage of TMR were 1, 0.75, 0.50, 0.25 and 0, based on fresh weight. As the proportion of DW decreased, the pH also decreased (P < 0.05), while lactic acid, lactic acid/ac...
Source: Animal Science Journal - July 1, 2017 Category: Zoology Authors: Guomei Yin, Chunsheng Bai, Juanjuan Sun, Lin Sun, Yanlin Xue, Yuanyuan Zhang, Heping Zhao, Zhu Yu, Sibo Liu, Kewei Zhang Tags: Original Article Source Type: research
