In vitro and in silico insights of Cupressus sempervirens, Artemisia absinthium and Lippia triphylla: Bridging traditional knowledge and scientific validation
Conclusion This study provides insight into the antioxidant capacity and the inhibitory potential of these medicinal plants against key enzymes linked to DMT2 and neurodegenerative disorders. (Source: European Journal of Integrative Medicine)
Source: European Journal of Integrative Medicine - June 1, 2017 Category: Complementary Medicine Source Type: research
The impact of a mixture of medicinal herbs on ruminal fermentation, parasitological status and hematological parameters of the lambs experimentally infected with Haemonchus contortus
Publication date: Available online 3 May 2017 Source:Small Ruminant Research Author(s): Z. Váradyová, S. Kišidayová, K. Čobanová, Ľ. Grešáková, M. Babják, A. Königová, M. Urda Dolinská, M. Várady The aim of this study was to determine the effect of dietary supplementation with a mixture of selected medicinal herbs (Herbmix) on hematological and parasitological parameters and on the inflammatory response of lambs infected experimentally with the gastrointestinal parasitic nematode Haemonchus contortus. Herbmix contained selected medicinal herbs common in central Europe (8.55% each of Althaea officin...
Source: Small Ruminant Research - May 4, 2017 Category: Zoology Source Type: research
Toxic essential oils. Part V: Behaviour modulating and toxic properties of thujones and thujone-containing essential oils of Salvia officinalis L., Artemisia absinthium L., Thuja occidentalis L. and Tanacetum vulgare L.
In this study, we employed a statistical approach to determine the contribution of thujones to the overall observed behaviour-modulating and toxic effects of essential oils (Salvia officinalis L., Artemisia absinthium L., Thuja occidentalis L. and Tanacetum vulgare L.) containing these monoterpene ketones. The data from three in vivo neuropharmacological tests on rats (open field, light-dark, and diazepam-induced sleep), and toxicity assays (brine shrimp, and antimicrobial activity against a panel of microorganisms), together with the data from detailed chemical analyses, were subjected to a multivariate statistical treatm...
Source: Food and Chemical Toxicology - May 1, 2017 Category: Food Science Authors: Radulović NS, Genčić MS, Stojanović NM, Randjelović PJ, Stojanović-Radić Z, Stojiljković NI Tags: Food Chem Toxicol Source Type: research
Discovery and Development of Artemisinin and Related Compounds
Publication date: April 2017 Source:Chinese Herbal Medicines, Volume 9, Issue 2 Author(s): Chang-xiao Liu Artemisinin is isolated from the plant Artemisia annua, sweet wormwood, an herb employed in traditional Chinese medicine. Prof. You-you Tu discovered artemisinin in the 1960s, so she was awarded the 2015 Nobel Prize in Physiology or Medicine. Artemisinin and its semi-synthetic derivatives are a group of drugs that possess the most rapid action of all current drugs against Plasmodium falciparum malaria. In this review, the author investigated history on discovery of artemisinin, ethnopharmacology of Artemisia plants,...
Source: Chinese Herbal Medicines - April 27, 2017 Category: Complementary Medicine Source Type: research
Atrial electrophysiological and molecular remodelling induced by obstructive sleep apnoea.
Abstract
Obstructive sleep apnoea (OSA) affects 9-24% of the adult population. OSA is associated with atrial disease, including atrial enlargement, fibrosis and arrhythmias. Despite the link between OSA and cardiac disease, the molecular changes in the heart which occur with OSA remain elusive. To study OSA-induced cardiac changes, we utilized a recently developed rat model which closely recapitulates the characteristics of OSA. Male Sprague Dawley rats, aged 50-70 days, received surgically implanted tracheal balloons which were inflated to cause transient airway obstructions. Rats were given 60 apnoeas p...
Source: J Cell Mol Med - April 12, 2017 Category: Molecular Biology Authors: Channaveerappa D, Lux JC, Wormwood KL, Heintz TA, McLerie M, Treat JA, King H, Alnasser D, Goodrow RJ, Ballard G, Decker R, Darie CC, Panama BK Tags: J Cell Mol Med Source Type: research
Atrial electrophysiological and molecular remodelling induced by obstructive sleep apnoea
Abstract
Obstructive sleep apnoea (OSA) affects 9–24% of the adult population. OSA is associated with atrial disease, including atrial enlargement, fibrosis and arrhythmias. Despite the link between OSA and cardiac disease, the molecular changes in the heart which occur with OSA remain elusive. To study OSA‐induced cardiac changes, we utilized a recently developed rat model which closely recapitulates the characteristics of OSA. Male Sprague Dawley rats, aged 50–70 days, received surgically implanted tracheal balloons which were inflated to cause transient airway obstructions. Rats were given 60 apnoeas per hour of ...
Source: Journal of Cellular and Molecular Medicine - April 12, 2017 Category: Molecular Biology Authors: Devika Channaveerappa, Jacob C. Lux, Kelly L. Wormwood, Timothy A. Heintz, Meredith McLerie, Jacqueline A. Treat, Hannah King, Donia Alnasser, Robert J. Goodrow, Glenn Ballard, Robert Decker, Costel C. Darie, Brian K. Panama Tags: Original Article Source Type: research
Thujone inhibits the function of α7-nicotinic acetylcholine receptors and impairs nicotine-induced memory enhancement in one-trial passive avoidance paradigm.
Abstract
Effects of thujone, a major ingredient of absinthe, wormwood oil and some herbal medicines, were tested on the function of α7 subunit of the human nicotinic acetylcholine (α7 nACh) receptor expressed in Xenopus oocytes using the two-electrode voltage-clamp technique. Thujone reversibly inhibited ACh (100μM)-induced currents with an IC50 value of 24.7μM. The effect of thujone was not dependent on the membrane potential and did not involve Ca(2+)-dependent Cl(-) channels expressed endogenously in oocytes. Inhibition by thujone was not reversed by increasing ACh concentrations. Moreover, specific...
Source: Toxicology - April 7, 2017 Category: Toxicology Authors: Sultan A, Yang KS, Isaev D, Nebrisi EE, Syed N, Khan N, Howarth CF, Sadek B, Oz M Tags: Toxicology Source Type: research
Poaceae, Secale spp. and Artemisia spp. pollen in the air at two sites of different degrees of urbanisation.
CONCLUSIONS: The risk of allergy caused by the pollen of the taxa analysed was much higher in Gudowo (in the country), than in Szczecin city.
PMID: 28378978 [PubMed - in process] (Source: Annals of Agricultural and Environmental Medicine : AAEM)
Source: Annals of Agricultural and Environmental Medicine : AAEM - March 21, 2017 Category: Environmental Health Authors: Kruczek A, Puc M, Wolski T Tags: Ann Agric Environ Med Source Type: research
Glucose-triggered Insulin Release from Fe3+-cross-linked Alginate Hydrogel: Experimental Study and Theoretical Modeling.
Abstract
We study the mechanisms involved in the release, triggered by the application of glucose, of insulin entrapped in Fe3+-cross-linked alginate hydrogel particles further stabilized with a polyelectrolyte. Platelet-shaped alginate particles are synthesized containing enzyme glucose oxidase conjugated with silica nanoparticles, which are also entrapped in the hydrogel. Glucose diffuses in from solution, and production of hydrogen peroxide is catalyzed by the enzyme within the hydrogel. We argue that, specifically for the Fe3+-cross-linked systems, the produced hydrogen peroxide is further converted to...
Source: Chemphyschem - March 15, 2017 Category: Chemistry Authors: Katz E, Scheja S, Domanskyi S, Gamella M, Wormwood KL, Darie CC, Poghossian A, Schöning MJ, Melman A, Privman V Tags: Chemphyschem Source Type: research
Deaths
Hannam On December 16, 2016, Avril Kathleen Hannam, BVSc, MSc, MRCVS, of Karibu, Knayton, Thirsk, North Yorkshire. Mrs Hannam qualified from Liverpool in 1973.
Mitchell On February 21, 2017, Thomas William Mitchell, BVMS, MRCVS, of Elizabethan House, Leicester Road, Lutterworth, Leicestershire. Mr Mitchell qualified from Glasgow in 1997.
Ryde On February 28, 2017, Paul Scrivener Ryde, BSc (VetSci), MRCVS, of Wormwood Green, The Green, Kersey, Ipswich. Mr Ryde qualified from London in 1949.
Schmitz On October 17, 2016, Charles Conrad Schmitz, BVSc, MRCVS, of Gauteng, Albermale 1410, South Africa. Mr Schmitz qualified from P...
Source: Veterinary Record - March 9, 2017 Category: Veterinary Research Tags: Gazette Source Type: research
Antioxidant Supplements and Gastrointestinal Diseases: A Critical Appraisal
The gastrointestinal tract digests and absorbs dietary nutrients; protects the body against physical and chemical damage from contents in its lumen; provides immunity against external antigens and keeps an optimum environment for the gut microbiota. These functions cannot be performed normally in several diseases of which the following are discussed here: irritable bowel syndrome, inflammatory bowel disease which includes Crohn's disease and ulcerative colitis. Because these diseases are associated with oxidative stress, a host of antioxidant supplements are used for maintenance and recovery of the gut functions. However, ...
Source: Medical Principles and Practice - March 9, 2017 Category: Internal Medicine Source Type: research
Flavonoids and Sesquiterpene Lactones from Artemisia absinthium and Tanacetum parthenium against Schistosoma mansoni Worms.
This report provides the first evidence for the in vitro activity of parthenolide against adult worms of S. mansoni, opening the route to further schistosomicidal studies with this compound.
PMID: 27980595 [PubMed - in process] (Source: Evidence-based Complementary and Alternative Medicine)
Source: Evidence-based Complementary and Alternative Medicine - December 18, 2016 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Quantitative and qualitative variation of volatile oil in Artemisia annua and A. absinthium species from wild populations in Republic of Moldova
Planta Med 2016; 81: S1-S381 DOI: 10.1055/s-0036-1596345 Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents | Full text (Source: Planta Medica)
Source: Planta Medica - December 13, 2016 Category: Drugs & Pharmacology Authors: Stefanache, CP Spac, A Bujor, OC Danila, D Ciocarlan, N Carlen, C Simonnet, X Tags: Abstracts Source Type: research
Artemisia campestris L.: Ethnomedicinal, phytochemical and pharmacological review
Publication date: Available online 21 October 2016 Source:Journal of Herbal Medicine Author(s): Ikram Dib, Luc Angenot, Atika Mihamou, Abderrahim Ziyyat, Monique Tits Artemisia campestris L. (Asteraceae) is a perennial herb, commonly known as field wormwood. It is widespread in Asia, North America, Europe and North Africa. The different parts of this plant are used as anthelmintic, antidiabetic, antihypertensive, emmenagogue, antivenom, and to treat digestive and cutaneous problems. An exhaustive bibliographic research of this plant has been carried out by means of scientific engines and databases like Google Schola...
Source: Journal of Herbal Medicine - October 21, 2016 Category: Complementary Medicine Source Type: research
Disgust evoked by strong wormwood bitterness influences the processing of visual food cues in women: An ERP study.
We presented 39 healthy normal-weight women (mean age: 22.5 years) with images depicting high-caloric meat dishes, high-caloric sweets, and low-caloric vegetables after they had either rinsed their mouth with wormwood tea (bitter group; n = 20) or water (control group; n = 19) for 30s. The bitter aftertaste of wormwood enhanced fronto-central early potentials (N100, N200) and reduced P300 amplitudes for all food types (meat, sweets, vegetables). Moreover, meat and sweets elicited higher fronto-central LPPs than vegetables in the water group. This differentiation was absent in the bitter group, which gave lower arousal ...
Source: Appetite - September 20, 2016 Category: Nutrition Authors: Schwab D, Giraldo M, Spiegl B, Schienle A Tags: Appetite Source Type: research
