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Comparison of the Predictive Roles of Risk Scores of In-Hospital Major Adverse Cardiovascular Events in Patients with Non-ST-Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention
Objective. We evaluated the relationship between various risk scores (SYNTAX score (SS), SYNTAX score-II (SS-II), thrombolysis in myocardial infarction (TIMI) risk scores and Global Registry of Acute Coronary Events (GRACE) risk scores) and major adverse cardiovascular events (MACE) in non-ST-elevation myocardial infarction (NSTEMI) patients undergoing percutaneous coronary intervention (PCI). Subjects and Methods: The study population were selected from among 589 patients who underwent coronary angiography with a diagnosis of NSTEMI. TIMI and GRACE risk scores were calculated. SS and SS-II were calculated in all patients,...
Source: Medical Principles and Practice - April 20, 2018 Category: Internal Medicine Source Type: research

Macrophage Migration Inhibitory Factor -173GC Variant Might Increase the Risk of Beh çet's Disease
Conclusion: We conclude that the CC genotype of MIF -173GC variant may be a risk factor in the pathogenesis of BD in Turkish population. However, further studies with larger samples are needed to address the exact role of this va riant in BD. (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - April 19, 2018 Category: Internal Medicine Source Type: research

Diabetes Self-Management: A Key for Better Health-related Quality of Life in Patients with Diabetes
Conclusions: Kuwaiti patients with diabetes showed a modest level of HRQOL. Patients’ DSM, gender, and diabetes complications were significant independent correlates to HRQOL. Appraisal of patients with diabetes’ HRQOL as an essential component of diabet es management in clinical settings is suggested. Further studies to examine the impact of good diabetes self-management on HRQOL improvement are needed. (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - April 17, 2018 Category: Internal Medicine Source Type: research

Experiences Of Individuals Concerning Combined Orthodontic and Orthognathic Surgical Treatment: A Qualitative Twitter Analysis
Conclusions: The findings from the present study can increase the awareness of clinicians involved in the combined orthodontic and orthognathic surgical treatment of patients with dentofacial deformities, allowing them to better educate and counsel their patients throughout the entire treatment process.Med Princ Pract (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - April 11, 2018 Category: Internal Medicine Source Type: research

Right ventricular functions in pulmonary thromboembolism
Conclusion:this is a letter to editor (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - April 5, 2018 Category: Internal Medicine Source Type: research

Prevalence and genotype distribution of hepatitis C virus infection among patients with type 2 diabetes mellitus
Conclusion:Patients with type 2 DM had a higher prevalence of HCV infection than controls, and this HCV seropositivity was independent of biochemical parameters. (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - April 5, 2018 Category: Internal Medicine Source Type: research

Isolated Renal Hydatid Cyst Misdiagnosed and Operated as a Cystic Renal Tumor
Conclusion: Isolated renal hydatid cyst could be misinterpreted as a renal tumor. It should be considered in the differential diagnosis of renal cystic lesions. (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - March 29, 2018 Category: Internal Medicine Source Type: research

Usefulness of Serum Omentin-1 Levels for the Prediction of Adverse Cardiac Events in Patients with Hypertrophic Cardiomyopathy
Conclusion: Omentin-1 levels were lower in patients with HCM than in the control group, and this was associated with worse cardiac outcomes.Med Princ Pract (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - March 22, 2018 Category: Internal Medicine Source Type: research

Evaluation and Exploration on the Effect of the Management of Chronic Obstructive Pulmonary Disease in Rural Areas Through Internet-based Network Consulting Room < br > < br >
This study aims to improve the management quality of chronic obstructive pulmonary disease (COPD) in rural areas. Methods: Two hundred forty discharged COPD patients were divided into an intervention group and a control group. In the intervention group, 120 patients established contact with doctors through the network consulting room, namely doctor's mobile platform, and were managed through video, voice, and text by the doctors, and kept in close contact with the doctors after discharge (education, consultation), and received electronic prescriptions, and drugs were sent to the door by online retailers. Patients in the co...
Source: Medical Principles and Practice - March 21, 2018 Category: Internal Medicine Source Type: research

Cadaver Dissection is Obsolete in Medical Training! A Misinterpreted Notion
Cadaver dissection is considered a tool for studying the structural details of the human body. Lately, conflicting opinions regarding the utility of this modality in medical training have been published in medical literature. This review of literature was done to examine the status of anatomy teaching with cadaver dissection in traditional, modern, and postgraduate medical training across the world. Literature published in the English language on topics related to cadaver dissection in the past three decades was scrutinized using different search engines. About 200 full texts were reviewed. This review describes how medica...
Source: Medical Principles and Practice - March 13, 2018 Category: Internal Medicine Source Type: research

Sanjad Sakati Syndrome: Oral Health Care
Conclusion: Recognition of oro-facial features might help in the diagnosis of Sanjad Sakati Syndrome. Dental management of affected patients might be complicated by intellectual, neurological and endocrine abnormalities. (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - March 13, 2018 Category: Internal Medicine Source Type: research

Ankle Nerve Block Adjuvant to General Anesthesia Reduces Post-surgical Pain and Improves Functional Outcomes in Hallux Valgus Surgery
Objective: Postoperative pain is a frequently problem after orthopedic procedures like hallux valgus surgery. The aim of this study was to evaluate whether ankle block improves early and mid-term functional outcomes and postoperative pain management after hallux valgus surgery in patients receiving general anesthesia. Subjects and Methods: This randomized controlled trial investigated 60 patients who underwent hallux valgus surgery under general anesthesia. Patients were prospectively randomized into two groups; general anesthesia only (Group A) and ankle block added to general anesthesia (Group B). Age, body-mass index (B...
Source: Medical Principles and Practice - March 13, 2018 Category: Internal Medicine Source Type: research

Cadaver Dissection is Obsolete in Medical Training! A Misinterpreted Notion.
Cadaver dissection is considered a tool for studying the structural details of the human body. Lately, conflicting opinions regarding the utility of this modality in medical training have been published in medical literature. This review of literature was done to examine the status of anatomy teaching with cadaver dissection in traditional, modern, and postgraduate medical training across the world. Literature published in the English language on topics related to cadaver dissection in the past three decades was scrutinized using different search engines. About 200 full texts were reviewed. This review describes how medica...
Source: Medical Principles and Practice - March 13, 2018 Category: Internal Medicine Source Type: research

Does Listening to Music during Tonsillectomy Affect Sevoflurane Consumption?
Objective: The aim of this study was to investigate the effect of listening to music on the consumption of an anesthetic agent as well as postoperative recovery and pain in children undergoing elective tonsillectomy. Materials and Methods: Fifty patients were randomized into those to whom music was played during surgery (Group M) and a control group to whom music was not played (Group C). The depth of anesthesia was provided by entropy levels of 50 ± 5 in both groups. Demographic characteristics and hemodynamic parameters were recorded perioperatively. The duration of surgery sevoflurane consumption, eye opening tim...
Source: Medical Principles and Practice - March 13, 2018 Category: Internal Medicine Source Type: research

Effects of Haloperidol on Delirium in Adult Patients: A Systematic Review and Meta-analysis
Conclusions: In this study, the limited available data revealed that prophylaxis haloperidol at dose of ≥ 5 mg/d might help reduce delirium in adult surgica l patients. Further outcome studies with larger sample sizes are required to confirm these findings. (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - March 9, 2018 Category: Internal Medicine Source Type: research

Methanolic Extract of Leathery Murdah, Terminalia coriacea (Roxb.) Wight and Arn. Leaves Exhibits Anti-inflammatory Activity in Acute and Chronic Models
Objective: The aim of present study was to evaluate anti-inflammatory activity of methanolic extract of Terminalia coriacea. Materials and Methods: A methanolic extract of Terminalia coriacea leaves was subjected to carrageenan-induced paw edema, an acute model, and cotton pellet-induced granuloma, a chronic model, at three oral test doses (125, 250 and 500 mg/kg) in albino Wistar rats. Aspirin 100 mg/kg was used as a positive control. Paw volume and wet and dry weights of cotton pellet were determined. The data was analyzed by one-way ANOVA followed by Dunnett ’s multiple comparison test. Results: The test extract a...
Source: Medical Principles and Practice - March 8, 2018 Category: Internal Medicine Source Type: research

Investigation of exposure factors for various breast composition and thicknesses in digital screening mammography related to breast dose
Conclusion: The use of Rh filter showed better image quality for all phantoms. 28 and 30 kVp with W/Rh combination provided slightly better image quality and the mean glandular dose is less than 1.2 mGy. (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - March 8, 2018 Category: Internal Medicine Source Type: research

Preoperative Midrregional Proadrenomedulin and High Sensitivity Troponin T Predict Perioperative Cardiovascular Events in Non-Cardiac Surgery
Objective: We evaluated the utility of preoperative mid-regional pro-adrenomedulin (MR-proADM) and cardiac troponin T (TnT) for improved detection of patients at high risk for perioperative cardiac events and mortality after major non-cardiac surgery. Subjects and Methods: This prospective, single-center, observational study enrolled 79 patients undergoing major non-cardiac surgery. After initial clinical assessment (clinical history, physical examination, echocardiogram, blood tests, and chest X-ray), mid-regional pro-adrenomedulin and high sensitivity troponin T (hsTnT) were measured within 48 hours prior to surgery by i...
Source: Medical Principles and Practice - March 8, 2018 Category: Internal Medicine Source Type: research

High Serum Thyrotropin Concentrations Within the Reference Range: A Predictor of Malignancy in Nodular Thyroid Disease
This study assesses whether or not a simple biochemical parameter, serum thyrotropin (TSH), within the reference range can predict the likelihood of thyroid malignancy in subjects undergoing fine-needle aspiration biopsy (FNAB) for thyroid nodules. Subjects and Methods: This cross-sectional study evaluated 236 patients without overt thyroid dysfunction who were not on levothyroxine therapy. They underwent FNAB of the thyroid nodules at the Clementino Fraga Filho University Hospital between 2011 and 2012. The reference range and serum TSH quartiles were determined according to age-specific values for serum TSH and then comp...
Source: Medical Principles and Practice - March 8, 2018 Category: Internal Medicine Source Type: research

Evaluation of Prolidase Activity, Oxidative Stress and Antioxidant Enzyme Levels in Testicular and Penile Tissues after Human Chorionic Gonadotropin Treatment in Rats by Predicting Infertility and Erectile Dysfunction
Objectives: Prolidase plays a vital role in collagen turnover, matrix remodeling and cell growth. We aimed to evaluate the association between treatment with chorionic gonadotropin and infertility and erectile dysfunction, by investigating tissue prolidase activity, oxidative stress and levels of antioxidant enzymes. Materials and Methods: Sixteen (16) male Wistar albino rats used in this study were randomly divided into two groups: rats treated with human chorionic gonadotropin (hCG) and control rats (n = 8 in each group). The rats in the hCG group were subcutaneously injected with 50 IU hCG daily for 15 days while the ra...
Source: Medical Principles and Practice - March 6, 2018 Category: Internal Medicine Source Type: research

Drug Resistance-Associated Mutations in Antiretroviral Treatment-Experienced Patients in Kuwait
Objectives: To investigate the prevalence of non-polymorphic resistance-associated mutations (RAMs) in HIV-1 patients on first-line antiretroviral therapy in Kuwait. Subjects and Methods: Total ribonucleic acid (RNA) was isolated from plasma samples of 42 patients who received first-line non-nucleoside reverse transcriptase inhibitor (NNRTI)-based regimen. HIV-1 protease and reverse transcriptase genetic regions were then amplified by nested reverse-transcription polymerase chain reaction (RT-PCR), and directly sequenced. HIV-1 subtype was identified using the Bayesian phylogenetic method, and resistance-associated mutatio...
Source: Medical Principles and Practice - March 6, 2018 Category: Internal Medicine Source Type: research

Potentially Inappropriate Prescribing in Older Adults with Hypertension or Diabetes Mellitus and Hypertension at Primary Care Setting in Bahrain
Conclusions: The prevalence of potentially inappropriate prescribing, 34.1%, was within the spectrum reported world-wide and unrelated to the training backgrounds of physicians. Most of the identified potentially inappropriate prescribing (76.3%) in older adults was associated with medications for acute medical illnesses hence inappropriate polypharmacy should be discouraged. (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - March 2, 2018 Category: Internal Medicine Source Type: research

Clinical and Radiographic Peri-implant Parameters and Whole Salivary Interleukin-1 beta and Interleukin-6 Levels Among Type-2 Diabetic and Non-Diabetic Patients with and without Peri-implantitis
Objective: The aim was to assess the peri-implant clinical and radiographic parameters and whole salivary levels of interleukin (IL)-1 β and IL-6 among type 2 diabetic and non-diabetic patients with and without peri-implantitis. Material and Methods: In group 1: 91 implants (39 patients with and 52 without peri-implantitis) were placed in patients without type 2 diabetes mellitus. In group 2: 80 implants (35 patients with and 45 p atients without peri-implantitis) were placed in patients with diabetes. Peri-implant plaque index, bleeding on probing, probing depth, and marginal bone loss were measured. Unstimulated who...
Source: Medical Principles and Practice - March 1, 2018 Category: Internal Medicine Source Type: research

The Effect of Allium cepa Extract on Lung Oxidant, Antioxidant and Immunological Biomarkers in Ovalbumin-Sensitized Rats
Objectives: To evaluate the effects of Allium cepa (A. cepa) on levels of oxidants, antioxidants and immunological markers in the broncho-alveolar lavage fluids in sensitized rats. Materials and Methods: Oxidant-antioxidant markers and cytokines in BALF of control rats treated with saline (group C), ovalbumin-sensitized rats (group S), rats treated with 1.25 μg/ mL dexamethasone and three doses (35, 70 and 140 mg/kg/day) of A. cepa extract (S+AC) were investigated. Comparison of the results between groups was done using analysis of variance with Tukey-Kramer’s post-test. Results: The oxidant markers nitrogen dioxi...
Source: Medical Principles and Practice - February 23, 2018 Category: Internal Medicine Source Type: research

The Relationship between Hypomagnesemia and Pulmonary Function Tests in Patients with Chronic Asthma
This study recruited 50 patients with chronic stable asthma and 40 healthy individuals as a control group. Data on age, sex, severity of asthma, PFT and details of drug therapy were obtained from each group. Serum magnesium, potassium, phosphorus, calcium, and sodium levels were also measured. Student ’s t test or Mann Whitney U test for continuous variables, and chi-square test for categorical variables were performed to evaluate differences between groups. Results: In the asthma group, 10% (n = 9) of the patients had hypomagnesemia and 5.5% (n = 5) of the patients had hypophosphatemia. Patie nts with asthma were di...
Source: Medical Principles and Practice - February 19, 2018 Category: Internal Medicine Source Type: research

List of Reviewers Vol. 26, 2017
Med Princ Pract 2017;26:593 –594 (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - February 16, 2018 Category: Internal Medicine Source Type: research

Contents Vol. 26, 2017
Med Princ Pract 2017;26:I –VIII (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - February 16, 2018 Category: Internal Medicine Source Type: research

A Comparison of the Effects of Grayanotoxin Containing Honey (Mad Honey), Normal Honey and Propolis on Fracture Healing
Conclusions: This study shows that grayanotoxin-containing "mad honey" and propolis can accelerate fracture healing. (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - February 11, 2018 Category: Internal Medicine Source Type: research

The Contribution of Whole Blood Viscosity to the Process of Aortic Valve Sclerosis
Objective: We aimed to investigate whether increased whole blood viscosity (WBV) could be an important factor for the occurrence of aortic valve sclerosis (AVS) Subjects and Methods: A total of 209 patients were enrolled into the study. WBV was calculated using the hematocrit and total plasma protein at a low shear rate (LSR) and high shear rate (HSR). AVS was defined as irregular valve thickening and calcification, without evidence of obstruction of outflow, as documented by a peak transvalvular velocity of (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - February 9, 2018 Category: Internal Medicine Source Type: research

"Real-life" Efficacy and Safety Aspects of Four-year Omalizumab Treatment for Asthma
Objective: To evaluate the long-term efficacy and safety of omalizumab in asthma in a real-life setting. Subjects and Methods: This was a 4-year observational study that included 65 patients treated with omalizumab during clinic visits; treatment response was rated as excellent, good and partial based on modified GETE (mGETE) scale. of emergency room visits (ERV), hospitalization, use of oral corticosteroids, inhaled corticosteroids/ long acting beta-agonist (ICS/LABA) dose, and short acting beta-agonist (SABA) rescue. The following tests: forced expiratory volume in one second (FEV1), asthma control test (ACT) were done. ...
Source: Medical Principles and Practice - February 8, 2018 Category: Internal Medicine Source Type: research

Focal Encephalitis, Meningitis and Acute Respiratory Distress Syndrome Associated with Influenza A Infection
Conclusion: This case report highlights focal encephalitis with concomitant pulmonary complications after influenza A infection. (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - February 5, 2018 Category: Internal Medicine Source Type: research

Metabolic Syndrome is Associated with Health-Related Quality of Life in Suspected Patients with Nonalcoholic Steatohepatitis
This study was designed to examine the effect of metabolic syndrome (MetS) on health-related quality of life (HRQOL) in patients with suspected nonalcoholic steatohepatitis (NASH). Subjects and Methods: Three hundred and thirty-two (332) patients (males: 236, females: 96) with suspected NASH from Amol cohort study were included in this study. The MetS was diagnosed based on Adult Treatment Panel III criteria (ATPIII) and HRQOL was measured with 12-Item Short Form Health Survey (SF-12) questionnaire (with eight subscales and two summary components). Multivariable linear regression model was used to assess the independent ef...
Source: Medical Principles and Practice - February 5, 2018 Category: Internal Medicine Source Type: research

Usefulness of Serum Omentin-1 Levels for the Predictions of Adverse Cardiac Events in Patients with Hypertrophic Cardiomyopathy
Objective: To investigate the association between serum omentin-1 levels and adverse cardiac events in patients with hypertrophic cardiomyopathy (HCM). Subjects and Methods: This prospective observational study included 87 patients with HCM and 50 age- and sex-matched control subjects. Serum omentin-1 and brain natriuretic peptide (BNP) levels were measured in all the subjects using enzyme-linked immunosorbent assay and electrochemiluminescence methods, respectively. Patients with HCM were divided into two groups according to omentin levels: low level: ≤ 291 ng/mL (n = 48) and high:>291 ng/mL (n = 39). Cardiac mortal...
Source: Medical Principles and Practice - February 5, 2018 Category: Internal Medicine Source Type: research

Effect of Transversus Abdominis-plane (TAP) Block on Postoperative pain after Colorectal Surgery: A Meta-analysis of Randomized Controlled Trials
Conclusions: TAP block was an effective approach for relief of postoperative pain, and reduced postoperative consumption of morphine. More RCTs with large sample sizes are required to confirm these findings. (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - February 2, 2018 Category: Internal Medicine Source Type: research

Primary Fused Teeth and Findings in Permanent Dentition
Conclusion: In this study, primary fused teeth were frequently observed in the mandibular ante rior region. Caries formation and dental anomalies, especially permanent tooth aplasia, were often encountered in areas where PFT were seen. Hence, parents should be informed about possible dental problems associated with primary fused teeth and to schedule regular follow-up. (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - February 2, 2018 Category: Internal Medicine Source Type: research

The Role of Signal Transducer and Activator of Transcription 5 and Transforming Growth Factor-Beta 1 in Hepatic Fibrosis Induced by Chronic Hepatitis C Virus Infection in Egyptian Patients.
Conclusion:STAT5 may play a significant role in hepatic fibrogenesis mostly through induction of TGF- β1, but not through HSC activation. (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - January 31, 2018 Category: Internal Medicine Source Type: research

Completeness and Legibility of Handwritten Prescriptions at Sana ’a, Yemen
Conclusion: In this study, the quality of prescription writing was found to be very poor. Hence, continuous professional development programs are recommended to improve the quality of prescription writing among physicians. Future studies in other cities and investigation of the impact of continuous educational programs on the quality of prescription writing are strongly recommended. (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - January 31, 2018 Category: Internal Medicine Source Type: research

Antibacterial Activity, Cytotoxicity and Mechanism of Action of Bacteriocin from Bacillus subtilis GAS101
Conclusion: Thermostable and pH tolerant bacteriocin form B. subtilis GAS101 of about 6.5 kDa showed broad spectrum antimicrobial and antibiofilm activity. (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - January 31, 2018 Category: Internal Medicine Source Type: research

Adverse Drug Reaction Reporting in Primary Care Setting in Kuwait: A Comparative Study of Physicians and Pharmacists
Objective: To investigate and compare the knowledge, attitude and practices regarding pharmacovigilance (PV) and reporting of adverse drug reactions (ADRs) among physicians and pharmacists in primary care settings. Subjects and Methods: A cross sectional study was conducted in which a validated self-administered questionnaire was distributed to 386 physicians and 197 pharmacists in 38 primary care clinics in Kuwait. Categorical variables were described using numbers and percentages. The Pearson chi-square, Fisher ’s exact or Mann-Whitney U tests were used, as appropriate. P values (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - January 30, 2018 Category: Internal Medicine Source Type: research

Hyoscine N-butylbromide for Preventing Propofol Injection Pain: A randomized, Placebo-controlled and Double-blind Study
In this study, the aim was to investigate the effect of the hyoscine N-butylbromide pretreatment on pain during propofol injection. Subjects and Methods: In this prospective, randomized, placebo-controlled and double-blind trial, 60 patients scheduled to undergo routine outpatient surgery under general anesthesia were allocated randomly to two groups: hyoscine N-butylbromide (n=30) and sodium chloride (n=30). Twenty (20) seconds after injection of 20 mg hyoscine N-butylbromide or 0.9 % sodium chloride, a 50-mg dose of propofol was injected within 2 –3 seconds. Ten seconds later, the pain intensity was assessed using ...
Source: Medical Principles and Practice - January 29, 2018 Category: Internal Medicine Source Type: research

Antispasmodic Effect of Black Currant (Ribes nigrum L.) Juice and its Potential Use as Functional Food in Gastrointestinal Disorders < br > < br > Corrected title: < br > Antispasmodic Effect of Black Currant (Ribes nigrum L.) Juice and its Potential Usage as Functional Food in Gastrointestinal Disorders
Objective: The purpose of this study was to investigate the relaxative effects of black currant juice on the gastrointestinal smooth muscle in vitro. Materials and Methods: Berries of black currant cultivar Ometa were used for preparation of juice used in this study. Spasmolytic activity of black currant juice was tested on rat ileum isolated from male Wistar rats by monitoring its influence on spontaneous contractions, as well as contractions induced by potassium-chloride (KCl), barium-chloride (BaCl2), calcium-chloride (CaCl2) and acetylcholine (Ach). The results were expressed as mean ± standard deviation obtaine...
Source: Medical Principles and Practice - January 29, 2018 Category: Internal Medicine Source Type: research

Evaluation of dynamic thiol-disulphide homeostasis in children and adolescents with non-autoimmune subclinical hypothyroidism
Conclusion:The status of dynamic thiol-disulfide homeostasis did not change in children and adolescents with non-autoimmune subclinical hypothyroidism. Long term follow-up studies in these patients are needed. (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - January 25, 2018 Category: Internal Medicine Source Type: research

Association of FTO rs9939609 with Obesity in The Kuwaiti Population: A Public Health Concern?
Conclusion: We observed an association between the common FTO rs9939609 polymorphism and increased BMI (overweight/obesity) in Kuwaiti adults which is consistent with previous research in other populations. Our findings encourage further investigation of genetic variants to elucidate the mechanis ms involved in the development of obesity in such an obesogenic population. (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - January 24, 2018 Category: Internal Medicine Source Type: research

Do Statins Affect Thyroid Volume and Nodule Size in Patients with Hyperlipidemia in a Mildly to Moderately Iodine-Deficient Region? A Prospective Study
The objective of this study was to assess the anti-proliferative pleiotropic effects of statins on thyroid function, volume and nodularity. Subjects and Methods: One hundred and six hyperlipidemic patients were included in this prospective study. Sixty nine patients in the statin groups received atorvastatin (16 patients received 10 mg, 18 received 20 mg) or rosuvastatin (20 patients received 10 mg, 15 received 20 mg); 37 patients in the control group assessed as not requiring drugs only made lifestyle changes. All patients were evaluated for lipid variables [total cholesterol, high-density lipoprotein cholesterol (HDL-C),...
Source: Medical Principles and Practice - January 24, 2018 Category: Internal Medicine Source Type: research

Abstracts of Theses Approved for MSc Degrees at the Faculty of Medicine, Health Sciences Center, Kuwait University, Kuwait: Abstracts
Med Princ Pract (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - January 16, 2018 Category: Internal Medicine Source Type: research

Abstracts of Award-Winning Posters, 22nd Annual Health Sciences Poster Conference, Faculty of Medicine, Health Sciences Centre, Kuwait University, Kuwait, March 7-9, 2017: Abstracts
Med Princ Pract (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - January 16, 2018 Category: Internal Medicine Source Type: research

Association between Antioxidant Enzyme Activities and Enterovirus-Infected Type 1 Diabetic Children
Conclusion: The present data indicate that enterovirus infection correlates with decreases in the antioxidant enzyme ac tivities in the T1D-EV+ group when compared to T1D-EV¯ group, which may contribute to β-cell damage and increased inflammation. (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - January 10, 2018 Category: Internal Medicine Source Type: research

Cholestatic Jaundice as a Paraneoplastic Manifestation of Prostate Cancer Aggravated by Steroid Therapy
Conclusion: Physicians should be aware of the possibility of paraneoplastic jaundice in patients with prostate cancer. Appropriate anti-androgen therapy should be considered for paraneoplastic jaundice in these patients. (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - January 10, 2018 Category: Internal Medicine Source Type: research

A Retrospective Analysis of Dialysis Events Over a 3-year period, in an Outpatient Dialysis Unit in the State of Kuwait
Conclusion: Dialysis event rates were higher among patients with tunneled or non-tunneled central lines in comparison to patients with fistula or graft. Gram-negative rods were the most commonly isolated microbial group. (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - January 5, 2018 Category: Internal Medicine Source Type: research

Tache Noire in a Patient with Acute Q Fever
Conclusion: In the Mediterranean area, tache noire should be considered pathognomonic of MSF but it should not rule out Q fever. Clinical diagnosis should be supported by accurate laboratory diagnostic tests to guide proper management (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - January 3, 2018 Category: Internal Medicine Source Type: research