Effects of Apnea, Obesity, and Statin Therapy on Proprotein Convertase Subtilisin/Kexin 9 Levels in Patients with Obstructive Sleep Apnea
Conclusion: Statin therapy was closely related toPCSK9. OSA along with obesity and statin use induces elevation ofPCSK9. (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - March 15, 2022 Category: Internal Medicine Source Type: research
Effects of Apnea, Obesity and Statin Therapy on Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) Levels in Patients with Obstructive Sleep Apnea
Conclusion: Statin therapy was closely related to PCSK9. OSA together with obesity and statin use induces elevation of PCSK9. (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - March 15, 2022 Category: Internal Medicine Source Type: research
Telerehabilitation during the COVID-19 Pandemic: Patients and Physical Therapists ’ Experiences
Conclusion: The patients as well as the PTs were generally satisfied with their telerehabilitation experiences. Using telerehabilitation in Kuwait was favoured as an adjunct method during and after the COVID-19 pandemic. However, with extensive training, optimal allocation of resources, and the development of local guidelines, telerehabilitation would become an effective mean for the health delivery system in Kuwait. (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - February 24, 2022 Category: Internal Medicine Source Type: research
Telerehabilitation During the COVID-19 Pandemic: Patients ’ Attitudes and Satisfaction and Physical Therapists’ Experiences
Conclusion: The patients as well as the physical therapists were generally satisfied with their telerehabilitati on experiences. Using telerehabilitation in Kuwait was favoured to be as an adjunct method during and after the COVID-19 pandemic. However, with extensive training, resources allocation, and the development of local guidelines, telerehabilitation would become an effective mean for the health deliver y system in Kuwait. (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - February 24, 2022 Category: Internal Medicine Source Type: research
Evaluation of Aortic Elasticity Parameters in Survivors of COVID-19 Using Echocardiography Imaging
This study compared arterial stiffness between the survivors of COVID-19 and those without a history of COVID-19 infection. The difference in aortic diameter was examined using echocardiography.
Results: The study included 50 patients who survived COVID-19 in the last 3 to 6 months and 50 age- and gender-matched healthy volunteers. In surviving COVID-19 patients, aortic diastolic diameter in cm ([3.1 ±0.2] vs. [2.9±0.1], p (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - February 16, 2022 Category: Internal Medicine Source Type: research
Severity of COVID-19 Symptoms among University of Belgrade Students during the July –September 2021 Pandemic Wave: Implications for Vaccination
Conclusion: Students who are vaccinated against COVID-19 are at lower risk of developing moderate and severe symptoms of the disease. (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - February 15, 2022 Category: Internal Medicine Source Type: research
Severity of Covid-19 Symptoms among University of Belgrade Students during the July-September 2021 Pandemic Wave: Implications for Vaccination
Conclusion: Students who were vaccinated against COVID-19 are at lower risk of developing moderate and severe symptoms of the disease. (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - February 15, 2022 Category: Internal Medicine Source Type: research
Comparative Bioavailability Study of Solid Self-Nanoemulsifying Drug Delivery System of Fenofibric Acid in Healthy Male Subjects
Conclusions: S-SNEDDS increased the dissolution rate in acid medium and absorption rate of fenofibric acid but did not increase the extent of fenofibric acid absorption. (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - February 8, 2022 Category: Internal Medicine Source Type: research
Comparative Bioavailability Study of Solid Self Nanoemulsifying Drug Delivery System
(S-SNEDDS) of Fenofibric Acid in Healthy Male Subjects
Conclusions: S-SNEDDS increased the dissolution rate in acid medium and absorption rate of fenofibric acid but did not increase the extent of fenofibric acid absorption. (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - February 8, 2022 Category: Internal Medicine Source Type: research
The Gut in Heart Failure: Current Knowledge and Novel Frontiers
Heart failure (HF) represents a major health problem affecting million people worldwide. In the latest years, many efforts have been made to search more effective strategies to prevent and modify the course of disease, but results are still not satisfying.
HF represents a complex clinical syndrome involving many other systems, including the gastrointestinal one. Although the relationship between gut and HF is far from being fully understood, based on recent evidences highlighting the putative role of gastrointestinal system in different cardiovascular diseases, it is conceivable that the link gut-heart may represent the b...
Source: Medical Principles and Practice - January 28, 2022 Category: Internal Medicine Source Type: research
Red Cell Distribution Width is independently associated with Mortality in Sepsis
Background: Mortality in sepsis remains high. Studies in small cohorts have shown that red cell distribution width (RDW) is associated with mortality. The aim of this study was to validate these findings in a large multi-centre cohort.
Methods: We conducted this retrospective analysis of the multi-center eICU Collaborative Research Database in 16,423 septic patients. We split the cohort in patients with low (≤15%; n=7,129) and high (>15%; n=9,294) RDW. Univariable and multivariable multilevel logistic regression were used to fit regression models for the binary primary outcome of hospital mortality and the secondary ou...
Source: Medical Principles and Practice - January 28, 2022 Category: Internal Medicine Source Type: research
Risk Factors for Surgery in Pediatric Patients with Crohn ’s Disease
I
Objective: Pediatric Crohn ’s disease has a more aggressive phenotype and course than in adults. Many patients develop complications that require surgery. The aim of this study was to identify the factors associated with increased risk for surgical intervention in pediatric patients with Crohn’s disease. Subjects and Meth ods: Retrospective review of medical records. We analyzed the following variables: sex, age at diagnosis, presenting symptoms, duration of symptoms before diagnosis, disease location and severity, presence of extraintestinal manifestations and presence of anti Saccharomyces cerevisiae antibodies. U...
Source: Medical Principles and Practice - January 27, 2022 Category: Internal Medicine Source Type: research
Risk Factors for Mortality in Patients with COVID-19: The Kuwait Experience
Conclusions: The mortality rate was higher in older patients with comorbidities s uch as hypertension and CVD. Early recognition of high-risk patients may help to improve care and reduce mortality. (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - January 26, 2022 Category: Internal Medicine Source Type: research
Noninvasive Investigation of the Presence and Extent of Coronary Artery Disease by the Evaluation of Fingertip-Reactive Hyperemia
Conclusion: RH-PAT is an objective and highly reproducible test with superior diagnostic accuracy for the evaluation of ED. We found significant correlations between ED and the presence and the severity of CAD. (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - January 20, 2022 Category: Internal Medicine Source Type: research
Non-invasive Investigation of the Presence and Extent of Coronary Artery Disease by the Evaluation of Fingertip Reactive Hyperemia
Conclusion: RH-PAT is an objective and highly reproducible test with superior diagnostic accuracy for the evaluation of ED. We found significant correlations between ED and the presence and the severity of CAD. (Source: Medical Principles and Practice)
Source: Medical Principles and Practice - January 20, 2022 Category: Internal Medicine Source Type: research
