Risk Factors for Surgery in Pediatric Patients with Crohn ’s Disease

I Objective: Pediatric Crohn ’s disease has a more aggressive phenotype and course than in adults. Many patients develop complications that require surgery. The aim of this study was to identify the factors associated with increased risk for surgical intervention in pediatric patients with Crohn’s disease. Subjects and Meth ods: Retrospective review of medical records. We analyzed the following variables: sex, age at diagnosis, presenting symptoms, duration of symptoms before diagnosis, disease location and severity, presence of extraintestinal manifestations and presence of anti Saccharomyces cerevisiae antibodies. Un ivariate analysis using the Mann-Whitney test and the Fisher’s exact test was performed to detect the factors associated with surgery. Potential risk factors with p
Source: Medical Principles and Practice - Category: Internal Medicine Source Type: research