The Possible Litholytic Effect of Ononis Spinosa L. on Various Human Kidney Stones – an in vitro experimental evaluation
This study aimed to investigate whether Ononis spinosa L. has a litholytic effect on kidney stones with different chemical patterns.Materials and MethodsUrinary stones extracted from seven patients over 18 years of age during surgery were used as the study material. Each urinary stone was divided into two parts, one of which was left in a solution prepared with O. spinosa L. and the other constituted the control sample. The amount of calcium, phosphor and uric acid passing through each solution was detected by spectrophotometric analysis to assess its efficiency and determine whether or not the urinary stones were dissolve...
Source: Journal of Herbal Medicine - February 20, 2020 Category: Complementary Medicine Source Type: research

Efficiency and Safety of Yueju Antidepressant for Primary Depression Patients: A Meta-analysis of Randomized Controlled Trials
This study was registered in the International Prospective Register of Systematic Reviews (PROSPERO), number CRD42017078860. PubMed, Embase, Cochrane Library; and the Chinese National Knowledge Infrastructure (CNKI), Vip information database, Wanfang data and Chinese Biomedical Literature Database (SINOMED), with no language restrictions, were searched from commencement of the study to September 2017. Randomized Controlled Trials (RCTs) with patients suffering from primary depression, who were given Yueju antidepressant alone or Yueju combined with a selective serotonin re-uptake inhibitor (SSRI) were compared with the res...
Source: Journal of Herbal Medicine - February 15, 2020 Category: Complementary Medicine Source Type: research

Medical and food ethnobotany among Albanians and Serbs living in the Shtërpcë/Štrpce area, South Kosovo
Publication date: Available online 13 February 2020Source: Journal of Herbal MedicineAuthor(s): Behxhet Mustafa, Avni Hajdari, Bledar Pulaj, Cassandra L. Quave, Andrea PieroniAbstractEthnobotanical research in the Balkans is important for providing concrete insights aimed at developing small-scale markets of local medicinal plants and food products to support rural development. An ethnobotanical field study was carried out in the spring of 2017 among Muslim Albanians and Christian Orthodox Serbs living in 20 villages located in South Kosovo. The aim of the study was to assess if two different ethnic affiliations played a r...
Source: Journal of Herbal Medicine - February 14, 2020 Category: Complementary Medicine Source Type: research

A Comparative Study of the Antioxidant and ACE Inhibitory Activities of Selected Herbal Extracts
Publication date: Available online 11 February 2020Source: Journal of Herbal MedicineAuthor(s): Neha Chaudhary, Latha Sabikhi, Shaik Abdul Hussain, Sathish Kumar M HAbstractSome herbal bioactives possess high antioxidant and angiotensin converting enzymes (ACE) inhibition activity, which affects blood pressure levels. Herbal bioactives promote health benefits via different molecular mechanisms and most of these mechanisms are yet to be fully elucidated. In the present study, health promoting potential of aqueous extracts of six herbs viz. Allium sativum L., Withania somnifera (L.) Dunal, Ocimum sanctum L., Hibiscus sabdrif...
Source: Journal of Herbal Medicine - February 13, 2020 Category: Complementary Medicine Source Type: research

A tale of two cinnamons: a comparative review of the clinical evidence of Cinnamomum verum and C. cassia as diabetes interventions
ConclusionWhile evidence supports the therapeutic benefit ofC. cassia, interchangeability of C. cassia and C. verum remains inconclusive. Further research is warranted to address the effectiveness and safety of these cinnamon species. Given the potential hepatotoxicity of C. cassia, RCTs that include liver function tests are required. Robust RCTs on C. verum are recommended to establish if its efficacy can match its safety profile. (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - February 13, 2020 Category: Complementary Medicine Source Type: research

Vitex negundo L. leaf extract inhibits IL-6 and TNF-α secretion and phagocytosis in human leukocytes
Publication date: Available online 5 February 2020Source: Journal of Herbal MedicineAuthor(s): K.W.J.C. Kariyawasam, P.D.N.N. Sirisena, H.L.C. Nanayakkara, W.D. Ratnasooriya, S.M. HandunnettiAbstractVitex negundo L. is used as an anti-inflammatory agent in Ayurveda and Sri Lankan traditional medicine. Here, the anti-inflammatory effects of an aqueous leaf extract (ALE) of V. negundo L. was investigated. The inhibitory effects of freeze-dried ALE (15.7–500 µg/mL) against interleukin-1β (IL-1β), interleukin-6 (IL-6), and tumour necrosis factor-α (TNFα) secretion by human mononuclear c...
Source: Journal of Herbal Medicine - February 6, 2020 Category: Complementary Medicine Source Type: research

New Concentration of Curcumin Orabase in Recurrent Aphthous Stomatitis: a randomized, controlled clinical trial
ConclusionsThe results showed that, administration of 5% of Curcumin is as effective as 0.1% of triamcinolone acetonide for treatment of aphthous lesions. Therefore, it could be used for patients with a contraindication against corticosteroids. (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - February 4, 2020 Category: Complementary Medicine Source Type: research

Significant decrease in the viability and tumor stem cell marker expression in tumor cell lines treated with curcumin
In this study we investigated the effect of curcumin on cancer cell viability, proliferation and suppression of CSCs markers (CD44, CD133, ALDH1) in vitro. Additionally, as limitations for curcumin application arise from its poor bioavailability, the stability of curcumin in different media conditions was investigated.The effect of curcumin on three cancer cell lines (A549, HCT116, 183E95) was investigated with MTT-assay, Flowcytometry, Immunofluorescence and western blotting. Stability of curcumin (diferuloylmethane) and curcuminoids (bisdemetoxycurcumin; desmetoxycurcumin) was determined by HPLC technique in A549 cells i...
Source: Journal of Herbal Medicine - February 2, 2020 Category: Complementary Medicine Source Type: research

Effects of green coffee extract supplementation on glycemic indexes, leptin, and obesity values in patients with non-alcoholic fatty liver disease
In conclusion, GCE supplementation improved glycemic parameters and obesity values and may be useful in the management of NAFLD complications. Trial registration number: IRCT201602113664N17 (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - January 31, 2020 Category: Complementary Medicine Source Type: research

Antibacterial activity of selected medicinal plants used by traditional healers in Genta Meyche (Southern Ethiopia) for the treatment of gastrointestinal disorders
This study was designed to investigate the antibacterial activity of selected medicinal plants used by the Genta Meyche community in Southern Ethiopia. Ethnomedicinal data was collected from 25 herbalists through semi-structured interviews and observations. Based on the highest use value (UV), plants were selected to be tested on pathogenic bacteria. A total of 26 ethnomedicinal plant species belonging to 17 families were collected and identified. The extraction of active compounds from the selected plants was carried out using five solvents. Roots (30.8%) and leaves (26.9%) were the plant parts most frequently used for th...
Source: Journal of Herbal Medicine - January 30, 2020 Category: Complementary Medicine Source Type: research

Phenolic profile and biological activities of decoctions from Santolina impressa, a Portuguese endemic species
Publication date: Available online 21 January 2020Source: Journal of Herbal MedicineAuthor(s): Ana Margarida Rodrigues, Pedro Luis Vieira Falé, Paulo Madeira, Rita Pacheco, Maria Helena Florêncio, Lia Ascensão, Maria Luisa Marques SerralheiroAbstractSantolina impressa Hoffmanns & Link is an aromatic Asteraceae species endemic to the southwest of Portugal. It is used in folk medicine as an herbal tea for gastrointestinal ailments and mouthwash antiseptic. The present study aimed to relate the chemical composition of decoctions from the aerial parts S. impressa with their antiacetylcholinesterase, ant...
Source: Journal of Herbal Medicine - January 22, 2020 Category: Complementary Medicine Source Type: research

Nepeta nuda ssp. nuda L. water extract: Inhibition of replication of some strains of Human Alpha herpes virus (genus Simplex virus) in vitro, mode of action and NMR-based metabolomics
Publication date: Available online 20 January 2020Source: Journal of Herbal MedicineAuthor(s): Anton Hinkov, Petia Angelova, Andrey Marchev, Yordan Hodzhev, Venelin Tsvetkov, Daniela Dragolova, Daniel Todorov, Kalina Shishkova, Veneta Kapchina-Toteva, Renald Blundell, Stoyan Shishkov, Milen GeorgievAbstractNepeta nuda L. has been used in traditional folk medicine for its diuretic, anti-asthmatic, antioxidant, spasmolytic, sedative and analgesic properties (attributed to the nepetalactones). In the present study, water extract from Nepeta nuda ssp. nuda L. was tested in order to study its’ effect on the replication of...
Source: Journal of Herbal Medicine - January 21, 2020 Category: Complementary Medicine Source Type: research

Determination of phytochemical composition, cytotoxicity, genotoxicity and mutagenicity of the hydroethanolic extract of Dolichandra unguis-cati L. leaves in human leukocytes
Publication date: Available online 16 January 2020Source: Journal of Herbal MedicineAuthor(s): Juliana Calil Brondani, Rachel de Lima, Michel Mansur Machado, Melânia Palermo ManfronAbstractIn order to identify deleterious effects on cell integrity and genome, this study aimed to assess the phytochemical composition, cytotoxicity, genotoxicity and mutagenicity of the hydroethanolic extract obtained from the leaves of Dolichandra unguis-cati (CELD). Validated methods were used to evaluate in vitro the genotoxicity (Alkaline Comet DNA), mutagenicity (Micronucleus Frequency), cytotoxicity (Cell Viability Assay), and phyt...
Source: Journal of Herbal Medicine - January 16, 2020 Category: Complementary Medicine Source Type: research

Ethnopharmacological survey of herbal remedies used for treating malaria in Yemen
In conclusion, this study provides a new ethnopharmacological database of anti-malarial remedies in Yemen, which will be useful in further pharmacological and phytochemical investigations.Graphical abstract (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - January 10, 2020 Category: Complementary Medicine Source Type: research

Bioactive constituents of Curcuma amada (mango ginger) rhizomes and their antifungal activity against human skin pathogens
This study demonstrated the efficacy of this plant used in traditional medicine to treat all kinds of skin diseases as practiced by many ethnic groups since antiquity.Graphical abstract (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - January 9, 2020 Category: Complementary Medicine Source Type: research

Lysiphyllum strychnifolium (Craib) A. Schmitz extract, a novel neuraminidase inhibitor of avian influenza virus subtype H5N1
Publication date: Available online 7 January 2020Source: Journal of Herbal MedicineAuthor(s): Sophida Sukprasert, Kanoktip Pansuksan, Kusuma SriyakulAbstractThe leaves and stems of Lysiphyllum strychnifolium (Craib) A. Schmitz (Fabaceae family) have been traditionally used in Thailand for detoxification and to treat pesticide poisoning in humans. To uncover novel uses of L. strychnifolium, the possible antiviral properties against avian influenza virus A, strain H5N1, were explored in this study. The ethanolic extracts of L. strychnifolium leaves and stems showed good inhibitory activities against H5N1 neuraminidase. Such ...
Source: Journal of Herbal Medicine - January 9, 2020 Category: Complementary Medicine Source Type: research

The effects of Citrus aurantium aroma on anxiety and fatigue in patients with Acute Myocardial Infarction: A Two-center, randomized, controlled trial
Publication date: Available online 23 December 2019Source: Journal of Herbal MedicineAuthor(s): Razieh Shirzadegan, Mohammad Gholami, Shirin Hasanvand, Afsaneh BeiranvandAbstractObjectivesAnxiety and fatigue affect the clinical course and quality of life in patients with Acute Myocardial Infarction (AMI). Complementary therapies are recommended for managing these symptoms. The present study was conducted to evaluate the effects of Citrus aurantium aroma on anxiety and fatigue in patients with AMI admitted to coronary care units.DesignIn this triple-blind, randomized, controlled, clinical trial, 80 patients with AMI were al...
Source: Journal of Herbal Medicine - December 25, 2019 Category: Complementary Medicine Source Type: research

Effects of both Aloe Vera gel and breast milk on the improvement of nipple soreness in lactating women- a randomized controlled trial
Publication date: Available online 19 December 2019Source: Journal of Herbal MedicineAuthor(s): Seideh Hanieh Alamolhoda, Parvaneh Mirabi, Faraz Mojab (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - December 19, 2019 Category: Complementary Medicine Source Type: research

Anti-HIV-1 and antibacterial potential of Hyptis radicans (Pohl) Harley & J.F.B. Pastore and Hyptis multibracteata Benth. (Lamiaceae)
This study provides the first evidence of the anti-HIV-1 and antibacterial activity for these two species of Hyptis.Graphical abstract (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - December 18, 2019 Category: Complementary Medicine Source Type: research

A Double-blind Randomized Controlled Trial of Curcumin for Improvement in Glycemic Status, Lipid Profile and Systemic Inflammation in β-Thalassemia Major
ConclusionsCurcumin improved insulin resistance, lipid profile and systemic inflammation by reducing HOMA-IR, TG, TG/HDL ratio and hs-CRP levels in β-thalassemia major patients. Curcumin may be useful as an adjuvant therapy for attenuation of the metabolic complications in these patients. (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - December 12, 2019 Category: Complementary Medicine Source Type: research

Herbal medicines used to treat diabetes in Southern regions of Pakistan and their pharmacological evidence
Publication date: Available online 10 December 2019Source: Journal of Herbal MedicineAuthor(s): Akash Tariq, Sehrish Sadia, Yang Fan, Shandana Ali, Rahila Amber, Sakina Mussarat, Mushtaq Ahmad, Waheed Murad, Muhammad Zafar, Muhammad AdnanAbstractDiabetes is the third leading cause of death in humans after cancer and cardiovascular disease due to its high global prevalence. The aims of the current study were to document and review pharmacologically ethnomedicinal uses of plants for the treatment of diabetes in selected remote regions of Pakistan. Field data was collected through semi-structured questionnaires and a literatu...
Source: Journal of Herbal Medicine - December 12, 2019 Category: Complementary Medicine Source Type: research

Rutin- serum albumin interaction in different media and its effective dose selection in radiation-induced cytotoxicity on human blood cells
Publication date: Available online 10 December 2019Source: Journal of Herbal MedicineAuthor(s): Priti Sengupta, Prasenjit Mondal, Souryadeep Mukherjee, Sarmishtha Chanda, Adity BoseAbstractIncreases in general circulatory time, half-life and bioavailability increase the efficacy of any drug molecule. Rutin (3, 3′, 4′, 5, 7 -pentahydroxyflavone-3-rhamnoglucoside) is a flavonoid known for its ability to regulate cell metabolism, gene expression, and protect against oxidative stress, although certain biophysical aspects of their functioning are not yet clear. Non protein and small protein molecules with electrophi...
Source: Journal of Herbal Medicine - December 12, 2019 Category: Complementary Medicine Source Type: research

The effect of Padma-hepaten herbal combination on the caries-inducing properties of Streptococcus mutans on orthodontic surfaces
Publication date: Available online 4 December 2019Source: Journal of Herbal MedicineAuthor(s): Farkash Yosi, Feldman Mark, Ginsburg Isaac, Shalish Miriam, Steinberg DoronAbstractDental biofilm is recognized as the primary cause of oral infections, caries being the most common. Orthodontic appliances might increase the risk for dental caries and white spot lesions. Phytomedicinal methods were shown to inhibit dental biofilm formation. The goal of this study was to examine whether Padma hepaten (PH), a polyphenolic formula derived from traditional Tibetan medicine, could inhibit the caries-inducing properties of S. mutans. B...
Source: Journal of Herbal Medicine - December 4, 2019 Category: Complementary Medicine Source Type: research

Anti-Candida albicans biofilm activity of extracts from two selected indigenous Algerian plants: Clematis flammula and Fraxinus angustifolia
Publication date: Available online 26 November 2019Source: Journal of Herbal MedicineAuthor(s): Asma Ourabah, Dina Atmani-Kilani, Nadjet Debbache-Benaida, Olga Kolesova, Lila Azib, Farah Yous, Malika Benloukil, Bruno Botta, Djebbar Atmani, Giovanna SimonettiAbstractCandida albicans biofilm is associated with high rates of morbidity and resistance to antifungals. The aim of the present study is to evaluate the anti-Candida albicans biofilm activity of some indigenous Algerian medicinal plant extracts: Clematis flammula and Fraxinus angustifolia and their influence on the virulence factors of C. albicans. The anti-biofilm ac...
Source: Journal of Herbal Medicine - November 27, 2019 Category: Complementary Medicine Source Type: research

Ethnobotanical study of medicinal plants used by K’Ho-Cil people for treatment of diarrhea IN Lam Dong province, Vietnam
ConclusionIn Vietnam, folk medicine has been widely used by many people without documentation for preservation and scientific study. This study contributes a database of anti-diarrhea plants used by K’Ho-Cil people living in BiDoup-Nui Ba National Park, Vietnam.Graphical abstract (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - November 27, 2019 Category: Complementary Medicine Source Type: research

A Quantitative Documentation of Traditionally-used Medicinal Plants from Northeastern Algeria: Interactions of Beliefs among Healers and Diabetic Patients
Publication date: Available online 19 November 2019Source: Journal of Herbal MedicineAuthor(s): Bouzabata Amel, F. MahomoodallyAbstractThe aim of the study was to quantitatively document the use of plant-based medicine for the management of diabetes in Northeastern Algeria. Samples of 300 diabetic patients and 20 traditional healers were interviewed in five districts within Northeastern Algeria. The study showed that 4% of patients used phytotherapy in the management of type 2 diabetes mellitus (DM2), 26.3% recommended the amalgamation of conventional medicine with phytotherapy as a complementary or alternative medicine ag...
Source: Journal of Herbal Medicine - November 20, 2019 Category: Complementary Medicine Source Type: research

Evaluation of Indigenous Knowledge of Medicinal Plants from Tall Dardyal Hills, Khyber Pakhtunkhwa, Pakistan
ConclusionQuantitative analysis indicated that medicinal plants are an integral part of the life of the inhabitants. Local flora is recognised as highly valuable and is reported to be used against various ailments. Most commonly reported diseases were arthritis, kidney stone, typhoid fever, stomach problems, hepatitis, jaundice and diabetes. Among these aliments, the most common in the study area were stomach disorders, diabetes and kidney stones. The possible cause of kidney stones may be the food habits of the inhabitants, as the locals prefer vegetables like spinach that contain high amounts of oxalate.Graphical abstrac...
Source: Journal of Herbal Medicine - November 20, 2019 Category: Complementary Medicine Source Type: research

Using Ginger Supplement in Adjunct with Non-surgical Periodontal Therapy Improves Metabolic and Periodontal Parameters in Patients with Type 2 Diabetes Mellitus (DM) and Chronic Periodontitis. A Double-Blind, Placebo-Controlled Trial
The objective of this study was to investigate the effects of ginger supplementation in adjunct with non-surgical periodontal therapy (NSPT) on metabolic and periodontal parameters in patients with type 2 DM (T2DM) and chronic periodontitis (CP).Material and methodsIn this double-blind clinical trial study, 50 T2DM patients with CP were randomly allocated to intervention and control groups and received either 2 g ginger or placebo (4 tablets) twice a day for 8 weeks. All subjects underwent NSPT during the intervention period. Fasting blood glucose (FBG), glycosylated hemoglobin levels (HbA1c), triglyceride (TG), tot...
Source: Journal of Herbal Medicine - November 10, 2019 Category: Complementary Medicine Source Type: research

The effect of Mullein capsule on uterine leiomyomas volume and the amount of menstrual bleeding: A randomized controlled trial
This study was conducted to evaluate the effect of oral Mullein capsule on asymptomatic uterine leiomyomas volume and the amount of menstrual bleeding. In this two-parallel arm triple-blind, randomized, controlled trial, 50 women were selected among women referred to the clinics affiliated to Tabriz University of Medical Sciences aged 18-50 years old, having at least one asymptomatic myoma greater than 2.5-cm, in Iran over 2017-2018. The participants were randomized into two groups. The first group (n = 25) received 400 mg of Mullein powder capsules and the second group (n = 25) received ...
Source: Journal of Herbal Medicine - November 8, 2019 Category: Complementary Medicine Source Type: research

Effect of Daily Ginger Consumption on Platelet Aggregation
ConclusionResults showed that ginger 4 g daily had an impact on platelet aggregation using Epinephrine only, with no change observed after dose increment. Platelet aggregation inhibition was higher among females using Arachidonic Acid only. (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - November 8, 2019 Category: Complementary Medicine Source Type: research

Boswellic Acids as Natural Anticancer Medicine: Precious Gift to Humankind
Publication date: Available online 15 October 2019Source: Journal of Herbal MedicineAuthor(s): Tarun Sharma, Snehasis JanaAbstractBoswellic acids (BAs) are the important active constituents of the plant Boswellia serrata which has been widely used for the treatment of several acute and chronic inflammatory diseases. These acids have shown their very potent anti-inflammatory activities in both in vitro and in vivo animal models. Also, their anti-arthritic, anti-rheumatic, anti-diarrhoeal, anti-hyperlipidemic, anti-asthmatic, anticancer, anti-microbial, analgesic activity, hepatoprotective, and immunomodulatory activities ha...
Source: Journal of Herbal Medicine - October 17, 2019 Category: Complementary Medicine Source Type: research

Study on the Potential Chemical Markers for the Discrimination between Raw and Processed Schisandrae Chinensis Fructus using UPLC-Q-TOF/MS Coupled with Multivariate Statistical Analyses
In this study, a rapid strategy which used ultra-high performance liquid chromatography combined with a triple quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF/MS) was coupled with multivariate statistical analyses to rapidly explore the potential chemical components as chemical markers. These proposed potential chemical markers were then validated. Schisandrae Chinensis Fructus (SCF) was selected as the research object, and batches of both crude and vinegar processed samples were determined using UPLC-Q-TOF/MS. The datasets of the tR-m/z pairs, ion intensities, and sample codes were subjected to a principal compone...
Source: Journal of Herbal Medicine - October 15, 2019 Category: Complementary Medicine Source Type: research

Downregulation of adipogenic genes in 3T3-L1 Pre adipocytes- a possible mechanism of anti-obesity activity of herbal decoction Varanadi Kashayam
The objective of this study was to investigate the effect of herbal decoction Varanadi kashayam on genes involved in adipocyte differentiation and lipid synthesis in 3T3-L1 pre-adipocytes. The mechanism of action of Varanadi kashayam on adipogenesis was investigated on 3T3-L1 cells using quantitative real-time PCR. Intracellular lipid staining Oil red O and Fluorescent Nile red was carried out to quantify lipid accumulation in 3T3-L1 cells. Treatment of pre-adipocyte with Varanadi kashayam reduced the differentiation of pre-adipocytes and lipid accumulation in 3T3-L1 cells. Real time-PCR analysis showed that Varanadi kasha...
Source: Journal of Herbal Medicine - October 11, 2019 Category: Complementary Medicine Source Type: research

Evaluation of Phenolic Bioactive-Linked Anti-Hyperglycemic and Helicobacter pylori Inhibitory Activities of Asian Basil (Ocimum spp.) Varieties
Publication date: Available online 9 October 2019Source: Journal of Herbal MedicineAuthor(s): Lokesh K Mishra, Dipayan Sarkar, Rao Mentreddy, Kalidas ShettyAbstractBasil (Ocimum spp.) is an important herb from the Lamiaceae family with a long history of use in traditional medicine and food applications. Thus, targeting basil varieties for developing herbal medicines against non-communicable chronic diseases (NCDs) such as type 2 diabetes has significant merit. The aim of this study was to screen Asian basil varieties with therapeutic potential for type 2 diabetes targeting relevant phenolic bioactive-linked antioxidant, an...
Source: Journal of Herbal Medicine - October 11, 2019 Category: Complementary Medicine Source Type: research

A triple-blind, randomized trial of a traditional compound as compared to 4% hydroquinone in melasma
This study aimed to evaluate the effect of an herbal combination product, including Cicer arietinum L. and Cucumis melo seeds on melasma as compared to 4% hydroquinone.MethodsThirty-two female patients with melasma which were more than 18 years of age, enrolled in the study and continued till the end. They applied Hydroquinone 4%, using 0.5 FTU (fingertip unit) on one side of the face and the prepared combined product (C. arietinum L. and C. melo seeds), using 0.5 FTU on the other side in a triple-blind manner for 12 weeks. The patients were evaluated every four weeks by digital photography, and melasma and severity index ...
Source: Journal of Herbal Medicine - September 28, 2019 Category: Complementary Medicine Source Type: research

Hypogymnia physodes – A lichen with interesting medicinal potential and ecological properties
Publication date: Available online 28 May 2019Source: Journal of Herbal MedicineAuthor(s): Elżbieta Studzińska-Sroka, Daria Zarabska-BożjewiczAbstractHypogymnia physodes (L.) Nyl. is a lichenized fungus within the Parmeliaceae family that commonly occurs in Europe and in many other parts of the world. As a result of the specific relationship between a heterotrophic fungus and an autotrophic photobiont - algae or cyanobacteria among others - some secondary compounds not found among plants are produced. So far the presence of depsidones: physodalic acid, physodic acid, 3-hydroxyphysodic acid, 2′-O-methylphysodic aci...
Source: Journal of Herbal Medicine - September 25, 2019 Category: Complementary Medicine Source Type: research

Standardization and formulation of an herbal appetite-stimulating drug from Gentiana olivieri
Publication date: Available online 21 September 2019Source: Journal of Herbal MedicineAuthor(s): Mohammad Azadbakht, Elham Nayebi, Reza Enayati Fard, Fatemeh KhaleghiAbstractThe roots of Gentiana olivieri (Gentianaceae), an Iranian indigenous plant, were studied with the aim of standardizing and preparing an appetite-stimulating drug. The bitterness value of the aqueous extract of the plant was evaluated for its efficacy as an appetite-stimulant. It was found to be very bitter, with a bitterness value of 33,183.5, which is comparable to the value reported for the internationally well-known bitter plant, Gentiana lutea L. I...
Source: Journal of Herbal Medicine - September 22, 2019 Category: Complementary Medicine Source Type: research

In vitro Evaluation of Biophysical Properties of an Artificial Saliva Produced from Aloe vera Gel’
In this study, the minerals and antimicrobial substances of human saliva were substituted by the beneficial components found in Aloe vera gel and then, the rheological behavior of the formulation, such as viscosity, surface tension, pH, and mechanical properties of substitute salivary fluids were analyzed in order to determine the efficacy of this product. A new protocol was presented for the standardization of a type of artificial saliva which showed desired biophysical behavior which more closely resembled human saliva. However, more clinical studies are needed to present this product as a mouth or throat lubricant to re...
Source: Journal of Herbal Medicine - September 22, 2019 Category: Complementary Medicine Source Type: research

A Chinese herbal formula shows beneficial effects on comorbid depression and coronary heart disease based on the philosophy of psycho-cardiology
Publication date: Available online 20 September 2019Source: Journal of Herbal MedicineAuthor(s): Ying Wang, Yu-Jie Liu, Feng-E Li, Zhi Guo, Jun Wang, Comorbid Depression and Coronary Heart Disease Research Group of Cangzhou Central HospitalAbstractDepression is one of the major risk factors for the development, progression and prognosis of coronary heart disease (CHD). Patients with depression and CHD have high mortality and morbidity. Conventional antidepressant therapies achieve limited success in CHD patients. The aim of the present study was to determine the efficacy of a formulation of Chinese herbal medicine called t...
Source: Journal of Herbal Medicine - September 22, 2019 Category: Complementary Medicine Source Type: research

Ethnopharmacological survey of medicinal plants traded in herbal markets in the Peloponnisos, Greece
ConclusionsBased on our results, the plant taxa of Salvia spp., Aloysia citriodora, Achillea millefolium, Calendula officinalis, Juniperus communis, Malva sylvestris, Matricaria chamomilla, Origanum vulgare, Thymbra capitata, Taraxacum and Tilia spp. and Zea mays had novel medicinal uses which deserve further investigation.Graphical abstract (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - September 22, 2019 Category: Complementary Medicine Source Type: research

Evaluations of biocidal potential of Euclea crispa stem bark extract and ability to compromise the integrity of microbial cell membrane
This study evaluates biocidal effect of Euclea crispa stem bark extract and determines time-kill kinetics of its potent fractions as well as membrane attack capability. Susceptibility of the bacterial cells and minimum inhibitory concentrations (MICs) were determined via agar-well diffusion and broth micro-dilution respectively, time-kill kinetics were evaluated at different concentrations over 2-h period and membrane attack potential was evaluated via scanning electron microscopy imaging and measurement of the amount of proteins and nucleic acids released from the cells. Maximum zone of inhibition (22 ±&thin...
Source: Journal of Herbal Medicine - September 19, 2019 Category: Complementary Medicine Source Type: research

Clinical randomized trial of topical Quercus infectoria ethanolic extract for the treatment of chronic diabetic ulcers
This study aimed to clinically assess the efficiency of Quercus infectoria solution for the treatment of chronic diabetic ulcers in patients. Quercus infectoria solution was pharmaceutically formulated. A multicenter randomized controlled trial was performed in diabetic patients with ulcers (Wagner Ulcer Classification grade 1-3), who received standard wound treatment (normal saline solution) plus Quercus infectoria solution (study group; n = 26) or the standard solution alone (control group; n = 25) for three months. The primary outcome measure was complete wound healing. Percentage reduction i...
Source: Journal of Herbal Medicine - September 14, 2019 Category: Complementary Medicine Source Type: research

α-glucosidase and α-amylase inhibitory activities of medicinal plants in Thai antidiabetic recipes and bioactive compounds from Vitex glabrata R. Br. stem bark
In this study, the 37 medicinal plants selected from two Thai folk antidiabetic recipes (Mor-Phon recipe and the recipe of Wang-Nam-Yen hospital, Thailand) were investigated for their potential anti-diabetic mechanisms via α-glucosidase and α-amylase inhibitory activities. The highest α-glucosidase inhibitory activity was observed in the ethanolic extracts of Salacia chinensis, Vitex glabrata, Senna siamea, Terminalia catappa, and Phyllanthus amarus and the highest α-amylase inhibitory activity was observed in the ethanolic extracts of T. catappa, V. glabrata, P. amarus, S. chinensis, and S. siamea....
Source: Journal of Herbal Medicine - September 11, 2019 Category: Complementary Medicine Source Type: research

Herbal Nano-formulations for Topical Delivery
Publication date: Available online 4 September 2019Source: Journal of Herbal MedicineAuthor(s): Saloni Khogta, Jahanvi Patel, Kalyani Barve, Vaishali LondheAbstractThe use of herbal medicines has gained popularity throughout the world in recent times. Often seen as natural alternatives with fewer side-effects than synthetic medicines, these medicinal plants and their phytochemical constituents are thought to have potential applications in the management of a wide range of health conditions. As such, many whole herbal preparations, herbal extracts and isolated phytocontituents have been subjected to pharmacological and clin...
Source: Journal of Herbal Medicine - September 5, 2019 Category: Complementary Medicine Source Type: research

Phytochemicals in Barringtonia species: Linking their traditional uses as food and medicine with current research
Publication date: Available online 14 August 2019Source: Journal of Herbal MedicineAuthor(s): Kin Weng Kong, Sarni Mat-Junit, Norhaniza Aminudin, Azlina Abdul-AzizAbstractResearch is ongoing to develop and discover new medicinal products and new medicinal crops, as evidenced by a rapid increase in the number of scientific publications. Malaysia and the tropical regions are rich in flora and fauna, however, only a limited number of species have been scientifically researched and fully commercialised. This review described an indigenous plant named Barringtonia, which is less researched but nonetheless has great potential to...
Source: Journal of Herbal Medicine - August 15, 2019 Category: Complementary Medicine Source Type: research

Herbal Medicine Treatments for Essential Tremor: A retrospective chart review study
ConclusionThis study suggests that treatment with Korean herbal medicine has the potential to reduce essential tremor symptoms. Further clinical investigations that prospectively evaluate the efficacy of the key Korean herbal formulas highlighted in this study are very much warranted. (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - August 14, 2019 Category: Complementary Medicine Source Type: research

Effect of selected herbal formulations on anthropometry and body composition in overweight and obese individuals: A Randomized, Double blind, Placebo-controlled study
ConclusionBoth formulations Trimad and Triphala have demonstrated a promising role in reducing weight, circumferential measures and body fat. (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - August 12, 2019 Category: Complementary Medicine Source Type: research

The effect of Plantago major seed and Almond gum on refractory asthma: A proof-of-concept study
Publication date: Available online 8 August 2019Source: Journal of Herbal MedicineAuthor(s): Majid Anushiravani, Farahzad Jabbari Azad, Ali Taghipour, Majid Mirsadraee, Jalil Tavakol afshari, Roshanak Salari, M. Javad Najafzadeh, Maryam Khoshkhui, Roger M. Engel, Masoumeh Kaboli FarshchiAbstractBackgroundAsthma is a chronic respiratory disease that affects more than 300 million people worldwide. Refractory asthma (RA) is characterized by poor control despite adequate treatment. Conditions like RA have led to a renewed interest in non-conventional approaches to managing asthma such as those used in Traditional Persian medic...
Source: Journal of Herbal Medicine - August 9, 2019 Category: Complementary Medicine Source Type: research

Influence of in vitro gastro-duodenal digestion on the antioxidant activity of single and mixed three “Jarilla” species infusions
Publication date: Available online 8 August 2019Source: Journal of Herbal MedicineAuthor(s): Monica P.A. Carabajal, Maria I. Isla, Claudio D. Borsarelli, Iris C. ZampiniAbstractZuccagnia punctata Cav. (Zp), Larrea cuneifolia Cav. (Lc) and Larrea divaricata Cav. (Ld), are shrubs commonly called “Jarillas” and used in Argentinian local communities as medicinal plants. In this work, phytochemical profile and antioxidant activity of infusions prepared from aerial parts and mixtures in different proportions, before and after a simulated gastro-duodenal digestion was determined. The main phytochemical groups, protein...
Source: Journal of Herbal Medicine - August 9, 2019 Category: Complementary Medicine Source Type: research

Garlic (Allium sativum L.) in the Management of Hypertension and Dyslipidemia – A Systematic Review
Publication date: Available online 24 July 2019Source: Journal of Herbal MedicineAuthor(s): Wai-Jo J. Chan, Andrew J. McLachlan, Edward J. Luca, Joanna E. HarnettAbstractThe herb garlic (Allium sativum L.) has traditionally been used to promote ‘cardiovascular health’. The aim of this systematic review was to evaluate the available evidence for the efficacy and safety of garlic in the management of hypertension and dyslipidemia and the quality of that evidence by utilising the elaborated CONSORT checklist. Double-blind randomized controlled trials written in English from inception to April 2017 were identified ...
Source: Journal of Herbal Medicine - July 26, 2019 Category: Complementary Medicine Source Type: research