Antiplaque and antimicrobial efficacy of polyherbal mouth rinse among adult human volunteers – A short term randomized controlled trial
Publication date: Available online 16 April 2019Source: Journal of Herbal MedicineAuthor(s): BR Chandrashekar, Ramesh Nagarajappa, K Mruthunjaya, Suma Shekar, MS Girish, Rupesh ThakurAbstractSystematic evaluation of plant extracts and their combinations offers new insights into the development of innovative drugs from plants. The authors evaluated the antiplaque and antimicrobial efficacy of a polyherbal mouth rinse, using 0.2% chlorhexidine as positive and saline based mouth rinse as negative controls among adult human volunteers. Thirty eligible adult human volunteers were recruited and pre intervention prophylaxis was c...
Source: Journal of Herbal Medicine - April 18, 2019 Category: Complementary Medicine Source Type: research

Ethnopharmacological survey of plants used in the traditional treatment of pain conditions in Mali
Publication date: Available online 11 April 2019Source: Journal of Herbal MedicineAuthor(s): Ombeline Danton, Aimé Somboro, Baba Fofana, Drissa Diallo, Lassine Sidibé, Catherine Rubat-Coudert, Fabien Marchand, Alain Eschalier, Sylvie Ducki, Pierre ChalardAbstractPain is among the major concerns of healthcare authorities across the world. It is complicated to diagnose, manage and treat. Current western treatments are successful to some extent in relieving pain; they provide minimum improvements in terms of physical and emotional functioning and are often accompanied by side effects. Finding new solutions in pa...
Source: Journal of Herbal Medicine - April 11, 2019 Category: Complementary Medicine Source Type: research

Plant use as a traditional method by women against vaginal discharge in western anatolia, turkey: a qualitative research study
ConclusionPeople should be informed regarding the possible potential adverse consequences of the use of traditional methods. Also, further research should be performed on women's health and widely applied traditional applications. (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - April 10, 2019 Category: Complementary Medicine Source Type: research

Clinical efficacy of a topical polyherbal formulation in the management of fluorouracil -associated hand-foot syndrome
ConclusionThis study shows that patients receiving the polyherbal hydrogel experienced less complications and symptoms associated with HFS. In summary, it seems that the use of the prepared polyherbal hydrogel was beneficial for cancer patients administered fluorouracil-chemotherapeutic agents.Graphical; abstract (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - April 10, 2019 Category: Complementary Medicine Source Type: research

Treating depression naturally: How flower essences can help rebalance your life. Chris Phillips. Floris Books, Edinburgh, 2017, Pp. £12.99/$19.95. ISBN 978-178250-427-6.
Publication date: Available online 4 April 2019Source: Journal of Herbal MedicineAuthor(s): Graeme Tobyn (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - April 6, 2019 Category: Complementary Medicine Source Type: research

Anti-inflammatory Action of YHQ by Regulating 5-LOX/COX-2/NF-κB/MAPKs/Akt Signaling Pathways in RAW 264.7 Macrophage cells
This study suggested that YHQ can be a preventive and potent therapeutic candidate for the management of inflammatory-mediated immune disorders.Graphical abstract (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - April 4, 2019 Category: Complementary Medicine Source Type: research

Bioactive Metabolites of Ganoderma lucidum: Factors, Mechanism and Broad Spectrum Therapeutic Potential
ConclusionThis review illustrates the broad spectrum therapeutic potential of secondary metabolites derived fromGanoderma and supports our understanding of the main pharmacologically active compounds present in this fungus. Insight into the actions of its secondary metabolites could further pave a way for establishing G. lucidum, as a pharmacologically important product. (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - April 4, 2019 Category: Complementary Medicine Source Type: research

Effect of Arctium lappa linne (Burdock) Root tea consumption on lipid profile and blood pressure in patients with knee osteoarthritis
ConclusionsIt is suggested that consumption of burdock root tea may improve lipid profile and blood pressure status in patients with knee OA. Further studies may need to confirm these effects. (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - April 3, 2019 Category: Complementary Medicine Source Type: research

Daily date vinegar consumption improves hyperlipidemia, β-carotenoid and inflammatory biomarkers in mildly hypercholesterolemic adults
The objective of this study was to determine the effects of date vinegar made from date pulp and pits on the serum lipid profile and inflammatory biomarkers of mildly hypercholesterolemic adults. Seventy-six subjects with mildly raised total cholesterol and LDL cholesterol were enrolled. Participants ingested 30 mL of either date vinegar or placebo daily together with their normal diets. Plasma lipids, inflammatory biomarkers, carotenoids, potassium, folic acid, urea and creatinine were measured at baseline after 4 weeks and after treatment. These results suggest that the date vinegar improved several serum lipid pr...
Source: Journal of Herbal Medicine - March 24, 2019 Category: Complementary Medicine Source Type: research

Daily date vinegar consumption improves hyperlipidemia, β- carotenoid and inflammatory biomarkers in mildly hypercholesterolemic adults
The objective of this study was to determine the effects of date vinegar made from date pulp and pits on the serum lipid profile and inflammatory biomarkers of mildly hypercholesterolemic adults. Seventy-six subjects with mildly raised total cholesterol and LDL cholesterol were enrolled. Participants ingested 30 mL of either date vinegar or placebo daily together with their normal diets. Plasma lipids, inflammatory biomarkers, carotenoids, potassium, folic acid, urea and creatinine were measured at baseline after 4 weeks and after treatment. These results suggest that the date vinegar improved several serum lipid pr...
Source: Journal of Herbal Medicine - March 18, 2019 Category: Complementary Medicine Source Type: research

Spirulina platensis supplementation, macrophage inhibitory cytokine-1 (MIC-1), oxidative stress markers and anthropometric features in obese individuals: a randomized controlled trial
Publication date: Available online 15 March 2019Source: Journal of Herbal MedicineAuthor(s): Atefeh Shariat, Mahdieh Abbasalizad Farhangi, Reihaneh ZeinalianABSTRACTBackgroundsObesity is associated with numerous chronic diseases. The current study was aimed at investigating the effects of Spirulina platensis on Macrophage inhibitory cytokine 1 (MIC-1), biomarkers of oxidative stress and anthropometric features in obese patients.MethodsFifty six obese individuals, aged between 20-50 years old, participated in the current trial and were randomly allocated into two groups of intervention and control receiving either Spirulina...
Source: Journal of Herbal Medicine - March 16, 2019 Category: Complementary Medicine Source Type: research

Wound healing potential of selected Southern African medicinal plants: a review
ConclusionsEmpirical evidence has shown that these components also facilitate wound healing through increased wound contraction, reepithelialisation and collagen synthesis. To help close the knowledge gap, the authors are actively studying the mechanisms and composition of a selection of plants that are frequently used to promote wound healing in the region. (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - March 9, 2019 Category: Complementary Medicine Source Type: research

Medicinal plants and their traditional uses in the highland region of Bordj Bou Arreridj (Northeast Algeria)
Publication date: Available online 21 February 2019Source: Journal of Herbal MedicineAuthor(s): Mohamed Djamel Miara, Hamdi Bendif, Khellaf Rebbas, Bounar Rabah, Mohammed Ait Hammou, Filippo MaggiAbstractIn the highlands of Bordj Bou Arreridj in Northeast Algeria, traditional knowledge about medicinal plants is still put to use, but has been poorly explored by researchers. In view of its natural and cultural richness and the socio-economic context, this area is an ideal location for the study of aromatic and medicinal plants and their traditional uses. The aim of this ethnobotanical study was to shed light on how medicinal...
Source: Journal of Herbal Medicine - February 23, 2019 Category: Complementary Medicine Source Type: research

In vitro bioactivity of extracts from seeds of Cassia absus L. growing in Pakistan
Publication date: Available online 17 January 2019Source: Journal of Herbal MedicineAuthor(s): Saeed Ahmad, Ayesha Hassan, Tayyeba Rehman, Abdul Basit, Anbreen Tahir, Muhammad Adeel ArshadAbstractCassia absus seeds are widely used in traditional medicine for treatment of skin infections, wound healing, hypertension, peptic ulcers and anuria. The current study evaluated the antioxidant, antibacterial, and enzyme inhibitory activity of extracts obtained from the seeds of C. absus L. (Leguminosae) to determine a mechanism for the traditional use of the seeds. Crude ethanolic extract of C.absus seeds was prepared by maceration...
Source: Journal of Herbal Medicine - February 21, 2019 Category: Complementary Medicine Source Type: research

Differing antibacterial and antibiofilm properties of Polypodium vulgare L. rhizome aqueous extract and one of its purified active ingredients–osladin
Publication date: Available online 29 January 2019Source: Journal of Herbal MedicineAuthor(s): Michał Gleńsk, Dorota Tichaczek-Goska, Kamila Środa-Pomianek, Maciej Włodarczyk, Carl A. Wesolowski, Dorota WojniczAbstractPolypodium vulgare L. (Polypodiaceae), the common polypody, is used in Polish traditional medicine as an expectorant to treat cough, chronic nephritis, and pyelonephritis. This is a first study that tests the antimicrobial properties of the osladin contained in P. vulgare rhizome aqueous extract. The osladin was isolated from the aqueous extract by resin column fractionation, crystallization and preparati...
Source: Journal of Herbal Medicine - January 30, 2019 Category: Complementary Medicine Source Type: research

Higher consumption of Allium vegetables may modulate insulin homeostasis: A longitudinal follow-up study
This study investigated the association between habitual consumption of allium vegetables (raw garlic and onion) and the incidence of insulin resistance (IR), β-cell dysfunction and hyperinsulinemia.MethodsAdult men and women, participants of the Tehran Lipid and Glucose Study (2006-2008 to 2009-2011), were recruited. Habitual dietary intakes were assessed using a validated semi-quantitative food frequency questionnaire. Fasting serum insulin (FSI) and fasting glucose were measured at baseline and again after 3 years. Homeostatic model assessment of insulin resistance (HOMA-IR) and HOMA of β-cell function were ca...
Source: Journal of Herbal Medicine - January 30, 2019 Category: Complementary Medicine Source Type: research

Comparison of the Effect of Topical Use of Nigella Sativa Oil and Diclofenac Gel on Osteoarthritis Pain in Older People: A Randomized, Double-blind, Clinical Trial
Publication date: Available online 23 January 2019Source: Journal of Herbal MedicineAuthor(s): Fatemeh Azizi, Fereshteh Ghorat, Mohammad Hassan Rakhshani, Mostafa RadAbstractOsteoarthritis is one of the most common diseases in the elderly. Herbal remedies create pain relief with appropriate clinical effects and less toxicity. We aimed to investigate the effect of Nigella sativa oil compared with diclofenac gel on the reduction of osteoarthritis pain in older people. This was a double-blind clinical trial. Samples were 52 men and women aged 60-80 years. They were selected using a convenience method, that were randomly assig...
Source: Journal of Herbal Medicine - January 24, 2019 Category: Complementary Medicine Source Type: research

In vitro Bioactivity of Extracts from Seeds of Cassia absus L.Growing in Pakistan
Publication date: Available online 17 January 2019Source: Journal of Herbal MedicineAuthor(s): Saeed Ahmad, Ayesha Hassan, Tayyeba Rehman, Abdul Basit, Anbreen Tahir, Muhammad Adeel ArshadAbstractCassia absus seeds are widely used in traditional medicine for treatment of skin infections, wound healing, hypertension, peptic ulcers and anuria. The current study evaluated the antioxidant, antibacterial, and enzyme inhibitory activity of extracts obtained from the seeds of C. absus L. (Leguminosae) to determine a mechanism for the traditional use of the seeds. Crude ethanolic extract of C.absus seeds was prepared by maceration...
Source: Journal of Herbal Medicine - January 18, 2019 Category: Complementary Medicine Source Type: research

Oregano and/or Marjoram: Traditional Oil Production and Ethnomedical Utilization of Origanum Species in southern Turkey
In this study, traditional oil production and ethnomedical utilization of plant products are presented from the Antalya region in southern Turkey. The native people harvest species from wild populations and air-dry them under the sun. They consume and sell mainly air-dried Origanum onites (Turkish oregano) leaves. They obtain essential oil traditionally by steam distillation from Origanum majorana (white marjoram) due to its high oil yield. The native people use dried plant material and essential oil to cure various diseases such as cough, chronic cold, wounds, gastrointestinal disorders and skin problems in humans as well...
Source: Journal of Herbal Medicine - January 11, 2019 Category: Complementary Medicine Source Type: research

Materia medica chests: investigating the 19th century use of botanicals by different medical professions
Publication date: Available online 6 January 2019Source: Journal of Herbal MedicineAuthor(s): Marion Mackonochie, Michael HeinrichAbstractThe use of herbal substances was an element of everyday medicine until the advent of synthetic medicines from the late 19th Century onwards. Medicinal chests were used as teaching and examination tools for apothecaries and pharmacists. The contents of two 19th Century materia medica chests that are owned by the Worshipful Society of Apothecaries in London (LSA) were analysed and compared with written texts from the time in order to understand botanical drug knowledge in 19th Century Brit...
Source: Journal of Herbal Medicine - January 6, 2019 Category: Complementary Medicine Source Type: research

Ethno-survey of Traditional Use of Plants as Aphrodisiacs in Kashmir Himalaya, India
Publication date: Available online 6 January 2019Source: Journal of Herbal MedicineAuthor(s): Aijaz Hassan Ganie, Bilal A. Tali, Gowhar. A. Shapoo, Irshad A. Nawchoo, Anzar A. KhurooAbstractDocumenting traditional use of biodiversity has assumed priority in conservation and sustainable use of this precious knowledge base. Of the various traditional uses of biodiversity, the utilization of plants to treat sexual disorders has a long history. Thus, the present study was carried out to survey and document the traditional use of plant species as aphrodisiacs in Kashmir Himalaya, India. It was discovered that 78 plant species g...
Source: Journal of Herbal Medicine - January 6, 2019 Category: Complementary Medicine Source Type: research

Neuroprotective effects of Hibiscus Sabdariffa against Hydrogen peroxide-induced toxicity
Publication date: Available online 17 December 2018Source: Journal of Herbal MedicineAuthor(s): Aiman Shalgum, Manoj Govindarajulu, Mohammed Majrashi, Sindhu Ramesh, Willard E. Collier, Gerald Griffin, Rajesh Amin, Chastity Bradford, Timothy Moore, Muralikrishnan DhanasekaranAbstractThe World Health Organization and the National Institute of Mental Health (United States of America) states that neurodegenerative diseases leads to significant loss of regular activity of the patients, their family and the caretakers leading to a huge economic loss. Current treatments provide modest and temporary symptomatic relief, without al...
Source: Journal of Herbal Medicine - December 18, 2018 Category: Complementary Medicine Source Type: research

Evaluation of biodegradable gel containing flax seed extract (Linum usitatissimum) as a targeted drug delivery for management of chronic periodontitis
Publication date: Available online 15 December 2018Source: Journal of Herbal MedicineAuthor(s): Pappu R, Varghese J, Koteshwara KB, Dr.Kamath V, Lobo R, K. NimmyAbstractTreatment of periodontitis has been one of the most challenging aspects of periodontal therapy. The role of host immune inflammatory response in periodontal disease forms the basis of modernistic therapeutic approaches. The present study evaluates the efficacy of an indigenously formulated flax seed extract in the form of biodegradable gel, as an adjunct in the treatment of chronic periodontitis. Sixty patients diagnosed with localized periodontal disease h...
Source: Journal of Herbal Medicine - December 16, 2018 Category: Complementary Medicine Source Type: research

Optimizing a recombinant estrogen receptor binding assay for analysis of herbal extracts
Publication date: Available online 10 December 2018Source: Journal of Herbal MedicineAuthor(s): Sandra L. Gray, Brett R. LackeyAbstractPhytoestrogens may directly or indirectly affect the function of estrogen receptors. A method using human recombinant estrogen receptors alpha and beta (ERα and ERβ) was adapted for pure isoflavone compounds: glycitein, glycitin, biochanin A and formononetin; and extracts from chaste tree, Queen-Anne’s lace, Cyperus rhizome, dong quai, flaxseed, black cohosh, Siberian ginseng, saw palmetto, hops, licorice, red clover and alfalfa. Estrogen binding equivalents (EBE) for extra...
Source: Journal of Herbal Medicine - December 12, 2018 Category: Complementary Medicine Source Type: research

Toxicology of medicinal plants and combinations used in rural northern KwaZulu-Natal (South Africa) for the treatment of hypertension
This study provides some insight into the possible toxicity implications of medicinal plants routinely used in rural northern KwaZulu-Nat. (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - December 6, 2018 Category: Complementary Medicine Source Type: research

Ethnopharmacological Studies, Chemical Composition, Antibacterial and Cytotoxic Activities of Essential Oils of Eleven Salvia in Iran
Publication date: Available online 27 November 2018Source: Journal of Herbal MedicineAuthor(s): Mojtaba Asadollahi, Omidreza Firuzi, Fatemeh Heidary Jamebozorgi, Marzieh Alizadeh, Amir Reza JassbiAbstractThe chemical compositions of essential oils (EOs) of 11 Salvia species collected from different localities in Iran were analyzed by GC-FID and GC-MS. Altogether, 58 compounds were identified. α- and β-Pinene, 1,8-cineol, β-caryophyllene and sclareol were detected as the major constituents. Moreover, the cytotoxic activity of the EOs were assessed against 3 human cancer cell lines (HT-29, MCF-7 and MO...
Source: Journal of Herbal Medicine - November 28, 2018 Category: Complementary Medicine Source Type: research

Efficacy of Darchini in the management of Polycystic Ovarian Syndrome: A randomized clinical study
ConclusionThe most important change was improvement in the menstrual pattern during the therapy. Our results support the fact that, despite the small metabolic and hormonal changes, cinnamon therapy is well tolerated by the majority of patients and may be clinically useful, especially in patients with menstrual disturbances in PCOS. Hence, cinnamon can be considered as an alternate therapy for the management of PCOS. (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - November 23, 2018 Category: Complementary Medicine Source Type: research

Black Salve Composition: An evaluation of the potential for Normal Tissue Toxicity and Treatment Failure from Black Salve Products
Publication date: Available online 19 November 2018Source: Journal of Herbal MedicineAuthor(s): Andrew Croaker, Graham J. King, John H. Pyne, Shailendra Anoopkumar-Dukie, Lei LiuAbstractBlack salve, used as an alternative skin cancer therapy, contains both herbal and chemical constituents, including extracts of the rhizomes of Sanguinaria canadensis and zinc chloride. Black salves may be ordered online and have been associated with cases of extensive tissue necrosis and treatment failures that have resulted in patient fatalities. Despite these adverse outcomes and continued use by patients, black salve products have not be...
Source: Journal of Herbal Medicine - November 21, 2018 Category: Complementary Medicine Source Type: research

Quercus Brantii Lindl. Vaginal Cream versus Placebo on Bacterial Vaginosis: a Randomized Clinical Trial
Publication date: Available online 20 November 2018Source: Journal of Herbal MedicineAuthor(s): Atefeh Zare, Zeinab Moshfeghy, Mohammad M. Zarshenas, Bahia Namavar jahromi, Marzieh Akbarzadeh, Mehrab SayadiAbstractThe current study aimed to compare the effects of Quercus brantii Lindl. vaginal cream in combination with metronidazole tablet on Bacterial Vaginosis (BV). A total of 176 eligible women with BV were enrolled. Diagnosis was based on having 3 or more signs described by Amsel’s criteria and a Nugent score of ≥7. Symptoms were evaluated before and after treatments. Participants were divided into two experim...
Source: Journal of Herbal Medicine - November 21, 2018 Category: Complementary Medicine Source Type: research

Inhibition of Key Enzymes Linked to Diabetes by Annona senegalensis Pers (Annonaceae) Leaf In vitro
This study was aimed at investigating the inhibitory potential of A. senegalensis leaf extracts and fractions on the activities of some enzymes (α-amylase and α-glucosidase) linked to diabetes. Plant samples were extracted with n-hexane (HEX), ethyl cetate (EtOAc) and ethanol (EtOH) and the extracts were subjected to in vitro antidiabetic studies. The most active extract was further fractionated using column chromatography and the fractions obtained were screened for the inhibitory activities whilst the possible bioactive compounds were determined by Gas Chromatography Mass Spectroscopy (GC-MS). From the result...
Source: Journal of Herbal Medicine - November 21, 2018 Category: Complementary Medicine Source Type: research

Nigella sativa improves anemia, enhances immunity and relieves iron overload-induced oxidative stress as a novel promising treatment in children having beta-thalassemia major
Publication date: Available online 17 November 2018Source: Journal of Herbal MedicineAuthor(s): Mohamed El-Shanshory, Nahed Mohammed Hablas, Moutasem Salih Aboonq, Ahmed R Fakhreldin, Mohammed Attia, Walaa Arafa, Reham A. Mariah, Hussam Baghdadi, Mongi Ayat, Mohammed Zolaly, Manal Mohamed Helmy Nabo, Hamdi H. Almaramhy, Samer Ahmed El-Sawy, Mona Zidan, Momen Elshazley, Rami Alharbi, Sayed Moustafa, Mostafa Abu-el Naga, Salah Mohamed El SayedAbstractIntroductionThalassemias are treated by regular blood transfusions and iron chelation therapy. Iron overload-induced oxidative stress helps the pathogenesis of thalassemia-induc...
Source: Journal of Herbal Medicine - November 18, 2018 Category: Complementary Medicine Source Type: research

Effect of Rosa canina L. (Rose-hip) on cold during winter season in a middle-class population: A randomized, double-blinded, placebo-controlled trial
This study aimed to test if a liquid standardised preparation, Hyben Vital, based on shells from Rose-hip (Rosa canina L.), reduces the incidence and symptoms of the common cold in Danish middle-class volunteers.MethodsVolunteers (n = 120) were randomly allocated to daily treatments with either 2 g of liquid Rose-hip (RH) or placebo (P) for six months during winter. Primary effect variables: The frequency of colds and symptoms related to cold. Secondary effect variables: Evaluations from diaries of muscle stiffness and general well-being (numerical scales).ResultsA number of 107 volunteers completed the trial and 31 ...
Source: Journal of Herbal Medicine - November 12, 2018 Category: Complementary Medicine Source Type: research

HPLC/LC-MS Guided Phytochemical and In vitro Screening of Astragalus membranaceus (Fabaceae), and Prediction of Possible Interactions with CYP2B6
In conclusion, the root extracts of A.membranaceus have been shown to inhibit CYP2B6, with IC50 values below the estimated hepatic circulation concentrations. This herb therefore may cause adverse drug interactions with CYPs, when co-administered with medications metabolized by CYP2B6.Graphical abstract (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - November 3, 2018 Category: Complementary Medicine Source Type: research

Ferula species: A rich source of antimicrobial compounds
Publication date: Available online 1 November 2018Source: Journal of Herbal MedicineAuthor(s): Zahra Boghrati, Mehrdad IranshahiAbstractFerula species, particularly F. assa-foetida and F. gummosa, have a long history of use in traditional medicine. They have extensively been used for the treatment of infectious diseases including diarrhea, skin infection, intestinal parasites and influenza.This review is an attempt to explore secondary metabolites from Ferula species as a rich source of molecules with antimicrobial property and highlights the gaps in our knowledge deserving future research. In this review, the authors expl...
Source: Journal of Herbal Medicine - November 2, 2018 Category: Complementary Medicine Source Type: research

Health-promoting properties of Corchorus leaves: A review
Publication date: Available online 29 October 2018Source: Journal of Herbal MedicineAuthor(s): Neetu Kumari, Shashi Bhushan Choudhary, Hariom Kumar Sharma, Binay Kumar Singh, Arroju Anil KumarAbstractThe genus Corchorus is commercially known for its phloem fibre. Moreover, the tender leaves of Corchorus have also long been recognized by Asian and African folk medicine practitioners to manage pain, fever, dysentery, sexual disorders and degenerative diseases. Given the significant medicinal properties attributed to the genus, the authors performed a thorough literature review to investigate the biological roles and toxicolo...
Source: Journal of Herbal Medicine - October 30, 2018 Category: Complementary Medicine Source Type: research

The effect of a mixture of Nigella sativa and Thymus vulgaris extracts in children with refractory epilepsies; A randomized trial
Publication date: Available online 27 October 2018Source: Journal of Herbal MedicineAuthor(s): Ali Akbar Momen, Ali Asghar Hemati, Gholamreza Hoshmand, Maryam Heydar Azadzadeh, Reza Azizi MalamiriAbstractMore than 25% of seizures in children are refractory to anti-seizure medications and need other modalities to control. Recently, herbal agents with anticonvulsive effects on seizure models in animals have received significant attention, but studies that show their impact on seizures in children are scarce. In a randomized, double-blind placebo-controlled cross-over design, we tried to demonstrate the efficacy of a mixture ...
Source: Journal of Herbal Medicine - October 27, 2018 Category: Complementary Medicine Source Type: research

Mechanisms of Action of Ginger in Nuclear Factor-kappaB Signaling Pathways in Diabetes
Publication date: Available online 21 October 2018Source: Journal of Herbal MedicineAuthor(s): Ahmad Saedisomeolia, Motahereh Makhdoomi Arzati, Mina Abdolahi, Mohsen Sedighiyan, Alejandra Rangel, Gerald Muench, Meysam Zarezadeh, Arash Jafarieh, Niyaz Mohammadzadeh HonarvarAbstractDiabetes mellitus is considered a metabolic disorder characterized by high blood sugar. Active disease is associated with low grade chronic inflammation resulting from the enhanced release of inflammatory mediators such as interleukin (IL)-1 β, IL-6, induced nitric oxide synthase, and cyclooxygenase-2 enzymes that lead to insulin resistance a...
Source: Journal of Herbal Medicine - October 21, 2018 Category: Complementary Medicine Source Type: research

An evaluation of garlic products available in Australian pharmacies–From the label to the laboratory
Publication date: Available online 21 September 2018Source: Journal of Herbal MedicineAuthor(s): Wai-Jo Jocelin Chan, Andrew J. McLachlan, Nial J. Wheate, Joanna E. HarnettAbstractGarlic is one of the most commonly used herbal medicines worldwide. There is medium quality evidence to support that specific garlic formulations at specific doses have an antihypertensive effect in a cohort of individuals with hypertension. There is lower quality evidence for garlic’s hypolipidaemic effects. While there are many garlic products available in Australian pharmacies, it is unclear if these products are formulated based on the ...
Source: Journal of Herbal Medicine - October 16, 2018 Category: Complementary Medicine Source Type: research

Evaluation of the anti-stress effects of five Tunisian aromatic and medicinal plants in vitro
Publication date: Available online 12 October 2018Source: Journal of Herbal MedicineAuthor(s): Mahmoud Ben Othman, Mohamed Neffati, Hiroko IsodaAbstractThe present study was designed to evaluate the anti-stress effects of the ethanol extracts of five medicinal plants from Southern part of Tunisia, traditionally used in folk medicine: Cymbopogon schoenanthus Spreng. (CSEE), Crithmum maritimum L. (CMEE), Arthrophytum scoparium (Pomel) ll’jin (ASEE), Artemisia herba-alba Asso. (AHEE), and Rhanterium suaveolens Desf. (RSEE). Assays using SH-SY5Y cells and HSP47-transformed CHO cells (HSP47+/- cells) were performed. Heat ...
Source: Journal of Herbal Medicine - October 13, 2018 Category: Complementary Medicine Source Type: research

Phytochemical characteristics and potential therapeutic properties of blue honeysuckle Lonicera caerulea L. (Caprifoliaceae)
Publication date: Available online 10 October 2018Source: Journal of Herbal MedicineAuthor(s): Rafał Becker, Anna SzakielAbstractLonicera caerulea, known as honeyberry, blue honeysuckle, sweet berry honeysuckle, edible honeysuckle, or haskap, is a perennial fruit-bearing plant belonging to the family Caprifoliaceae. Currently, the cultivation of this plant species is becoming increasingly popular due to the early ripening of the fruits, the plant´s exceptional resistance to frost, pests, and diseases, as well as for its potential health-promoting and therapeutic properties. Phytochemical analysis of blue honeysuckle...
Source: Journal of Herbal Medicine - October 12, 2018 Category: Complementary Medicine Source Type: research

Case report on recovery from Japanese encephalitis virus infection by complementary use of phytolacca-mother tincture and in silico analysis
Publication date: Available online 6 October 2018Source: Journal of Herbal MedicineAuthor(s): Harish Chandra Chaudhury, Akhil Kumar Panda, Sarat Kumar Behera, Manjushree Mohanty, Bharat Bhusan SubudhiAbstractPhytolacca Americana Lor pokeweed has medicinal application against inflammation, arthritis, and viral fever infections in traditional medicines. Its mother tincture in the homeopathic system of medicine is used for many of these disease conditions. This is the first case study reporting the beneficial effects of Phytolacca-mother tincture against Japanese Encephalitis Virus (JEV) infection in an intensive care unit (I...
Source: Journal of Herbal Medicine - October 8, 2018 Category: Complementary Medicine Source Type: research

A clinical review of the effectiveness of tomato (Solanum lycopersicum) against cardiovascular dysfunction and related metabolic syndrome
In conclusion, consuming fresh tomato supplements may contribute to the prevention of obesity, diabetes and cardiovascular dysfunctions through positively affecting biochemical pathways associated with these conditions. (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - October 5, 2018 Category: Complementary Medicine Source Type: research

Validation of Medicinal Herbs for Anti-tyrosinase Potential
Publication date: Available online 24 September 2018Source: Journal of Herbal MedicineAuthor(s): Pulok K. Mukherjee, Rajarshi Biswas, Akanksha Sharma, Subhodip Banerjee, Sayan Biswas, C.K. KatiyarAbstractTyrosinase is a key regulatory multifunctional enzyme containing copper that is responsible for the biosynthesis of melanin that determines the color of the skin. Accumulation of excessive melanin causes various dermatological disorders including melasma and age spots. Also, tyrosinase is responsible for enzymatic browning reactions in damaged fruits and vegetables. It deteriorates the color clarity of plant-derived food p...
Source: Journal of Herbal Medicine - October 5, 2018 Category: Complementary Medicine Source Type: research

Ethnopharmacological survey of plants used by the Bhil and Bhilala ethnic community in dermatological disorders in Western Madhya Pradesh, India
ConclusionsThe survey was able to identify and record the broad range of medicinal plants and practices used by the Bhil and Bhilala people in their treatment of dermatological conditions. The data collected is valuable, not only as part of the process of documenting and preserving a traditional knowledge and culture in danger of being lost, but also in its provision of a broad selection of medicinal plants that could be subjected to further pharmacological and clinical investigation for their potential role in the treatment of dermatological conditions.Graphical abstract (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - October 5, 2018 Category: Complementary Medicine Source Type: research

An evaluation of garlic products available in Australian pharmacies - from the label to the laboratory
Publication date: Available online 21 September 2018Source: Journal of Herbal MedicineAuthor(s): Wai-Jo Jocelin Chan, Andrew J. McLachlan, Nial J. Wheate, Joanna E. HarnettAbstractGarlic is one of the most commonly used herbal medicines worldwide. There is medium quality evidence to support that specific garlic formulations at specific doses have an antihypertensive effect in a cohort of individuals with hypertension. There is lower quality evidence for garlic’s hypolipidaemic effects. While there are many garlic products available in Australian pharmacies, it is unclear if these products are formulated based on the ...
Source: Journal of Herbal Medicine - September 22, 2018 Category: Complementary Medicine Source Type: research

Efficacy of Nardostachys jatamansi DC. in the management of Premenstrual Syndrome: A randomized controlled study
Publication date: Available online 20 September 2018Source: Journal of Herbal MedicineAuthor(s): Rabia malik, Muzafar D A Bhat, Kousar Fathima FAbstractAimsThe aim of the present study was to examine the efficacy and safety of Nardostachys jatamansi in reducing PMS symptoms in otherwise healthy women.MethodsThis single-blind, randomized, placebo-controlled study was conducted with 60 women aged between 18 and 45 years. The participants were randomly allocated to receive either a total of 4 g of N. jatamansi (2 capsules 3 times a day) or placebo for the 15 days prior to menstruation, for two consecutive menstrual cyc...
Source: Journal of Herbal Medicine - September 21, 2018 Category: Complementary Medicine Source Type: research

Diabetes mellitus and nature’s pharmacy of putative antidiabetic plants
Publication date: Available online 6 September 2018Source: Journal of Herbal MedicineAuthor(s): Kazhila C. ChinsembuAbstractGlobally, diabetes causes about 1.5 million deaths per year. Data predicts that the current global epidemiological burden of diabetes is increasing alongside its long-term life threatening sequelae and side-effects from synthetic antidiabetic drugs. Challenges in the public healthcare delivery system, inadequate human and financial resources, expensive antidiabetic drugs coupled with their limited availability, efficacy and tolerability, and a higher priority for subventions to the control of communic...
Source: Journal of Herbal Medicine - September 7, 2018 Category: Complementary Medicine Source Type: research

Ethnomedicinal knowledge of the Garo community of two villages in western Assam, India
Publication date: Available online 3 September 2018Source: Journal of Herbal MedicineAuthor(s): Simi Talukdar, Abhik GuptaAbstractThe present study documents the use of medicinal plants by the Garo tribe of Betagaon-Bamunpara (BB) and Nigamghola (NG) villages of western Assam in the northeastern region of India. Comparisons of ethnomedicinal practices in BB and NG between themselves as well as with the other Garo communities of the region and in Bangladesh have also been made. The methodology comprised interviews and focal group discussions with traditional healers and knowledgeable elderly persons. Plants were collected f...
Source: Journal of Herbal Medicine - September 4, 2018 Category: Complementary Medicine Source Type: research

Ethnopharmacological profile of anti-arthritic plants of Asia-A systematic review
ConclusionThe present review summarizes the ethnomedicinal information of anti-arthritic plants and discloses scientific gaps in current knowledge. The majority of reported plants have not yet been scientifically authenticated and should be given more attention in future, especially those plants i.e. Carica papaya L. being used in more than one country. (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - August 11, 2018 Category: Complementary Medicine Source Type: research

Fennel oil: A promising antifungal agent against biofilm forming fluconazole resistant Candida albicans causing vulvovaginal candidiasis
ConclusionFennel oil alone or in combination with fluconazole could provide a promising approach to the management of VVC caused by drug-resistant strains. (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - August 9, 2018 Category: Complementary Medicine Source Type: research