Phytochemical screening of Artemisia arborescens L. by means of advanced chromatographic techniques for identification of health-promoting compounds
Publication date: 5 January 2016 Source:Journal of Pharmaceutical and Biomedical Analysis, Volume 117 Author(s): Rosaria Costa, Salvatore Ragusa, Marina Russo, Giovanna Certo, Flavio A. Franchina, Antonio Zanotto, Elisa Grasso, Luigi Mondello, Maria Paola Germanò Artemisia arborescens, also known as tree wormwood, is a typical species of the Mediterranean flora. It has been used in folk medicine for its antispasmodic, anti-pyretic, anti-inflammatory, and abortifacient properties. In the current study, the application of multidimensional comprehensive gas chromatography (GC×GC), allowed to obtain a ...
Source: Journal of Pharmaceutical and Biomedical Analysis - October 28, 2015 Category: Drugs & Pharmacology Source Type: research

Caruifolin D from artemisia absinthium L. inhibits neuroinflammation via reactive oxygen species-dependent c-jun N-terminal kinase and protein kinase c/NF-κB signaling pathways.
In this study, we reported that caruifolin D significantly inhibited the productions of various neuroinflammatory mediators from microglia in response to bacterial lipopolysaccharide stimulation. Moreover, anti-inflammatory mechanism study showed that caruifolin D markedly suppressed the production of intracellular reactive oxygen species, which was an important player involved in neuroinflammation, leading to inhibitory effects on the activations of protein kinase C (PKC) and c-Jun N-terminal kinase (JNK), which were two major neuroinflammatory signaling pathways in the brains. Furthermore, caruifolin D protected neurons ...
Source: European Journal of Pharmacology - October 8, 2015 Category: Drugs & Pharmacology Authors: Zeng KW, Liao LX, Song XM, Lv HN, Song FJ, Yu Q, Dong X, Jiang Y, Tu PF Tags: Eur J Pharmacol Source Type: research

Green synthesis and characterization of silver nanoparticles using Artemisia absinthium aqueous extract — A comprehensive study
This study presents a comprehensive investigation of the differential behavior of plant extract and AgNO3 to synthesize biologically stable AgNPs. Graphical abstract (Source: Materials Science and Engineering: C)
Source: Materials Science and Engineering: C - September 5, 2015 Category: Materials Science Source Type: research

Localization of 45S and 5S rDNA sites and karyotype of Chrysanthemum and its related genera by fluorescent in situ hybridization
Publication date: October 2015 Source:Biochemical Systematics and Ecology, Volume 62 Author(s): Xiangyu Qi, Fei Zhang, Zhiyong Guan, Haibin Wang, Jiafu Jiang, Sumei Chen, Fadi Chen The phylogenetic relationships among Chrysanthemum and its related genera (Anthemideae, Asteraceae) is poorly understood. In the present study, these relationships were investigated using 45S and 5S ribosomal DNA (rDNA)-targeted fluorescent in situ hybridization. The results showed that there were two 45S rDNA signals present in Crossostephium chinense, four 45S rDNA signals in Cercidiphyllum japonicum, Artemisia sieversiana, A...
Source: Biochemical Systematics and Ecology - August 30, 2015 Category: Biochemistry Source Type: research

Comparative two‐dimensional polyacrylamide gel electrophoresis of the salivary proteome of children with autism spectrum disorder
Abstract In the last decades, prevalence of autism spectrum disorder (ASD) has been on the rise. However, clear aetiology is still elusive and improvements in early diagnosis are needed. To uncover possible biomarkers present in ASD, we used two‐dimensional polyacrylamide gel electrophoresis and nanoliquid chromatography‐tandem mass spectrometry (nanoLC‐MS/MS), to compare salivary proteome profiling of children with ASD and controls. A total of 889 spots were compared and only those spots with a fold change ≥1.7 and a P‐value <0.05 or a fold change of ≥3.0 between ASD cases and controls were analysed by nano...
Source: Journal of Cellular and Molecular Medicine - August 20, 2015 Category: Molecular Biology Authors: Armand G. Ngounou Wetie, Kelly L. Wormwood, Laci Charette, Jeanne P. Ryan, Alisa G. Woods, Costel C. Darie Tags: Original Article Source Type: research