Effect of dry medicinal plants (wormwood, chamomile, fumitory and mallow) on in vitro ruminal antioxidant capacity and fermentation patterns of sheep
The objective of this study was to determine the effect of dry medicinal plants (wormwood, chamomile, fumitory and mallow) and dietary substrates containing a mix of the plants on the end products of in vitro ruminal and intestinal fermentation, rumen protozoan population and ruminal antioxidant capacity of sheep. The experiment consisted of fermentations with the four plants used individually as the sole substrate and fermentation of a mix of medicinal plants (Plants): meadow hay:barley grain (MH:B), 700/300 w/w and Plants:MH:B, 100/600/300 w/w/w. The experiment was conducted using the in vitro gas production technique (I...
Source: Journal of Animal Physiology and Animal Nutrition - March 24, 2020 Category: Zoology Authors: Daniel Petri č, Dominika Mravčáková, Katarína Kucková, Klaudia Čobanová, Svetlana Kišidayová, Adam Cieslak, Sylwester Ślusarczyk, Zora Váradyová Tags: ORIGINAL ARTICLE Source Type: research

The Effect of Auxin and Auxin-Producing Bacteria on the Growth, Essential Oil Yield, and Composition in Medicinal and Aromatic Plants.
uml;rk F, Ali B Abstract Aromatic plants had been used since ancient times for their preservative and medicinal properties, and to impart aroma and flavor to food. Also their secondary metabolites are economically important as drugs, flavor and fragrances, pharmaceuticals, agrochemicals, dye, and pigments, pesticides, cosmetics, food additives, other industrially biochemical, and also play a major role in the adaptation of plants to their environment. Indole acetıc acid-producing rhizobacteria inoculations increase in stomatal density and level of secondary metabolite and have a synergistic effect on monoter...
Source: Current Microbiology - February 20, 2020 Category: Microbiology Authors: Çakmakçı R, Mosber G, Milton AH, Alatürk F, Ali B Tags: Curr Microbiol Source Type: research

Molecules, Vol. 25, Pages 413: Multifunctional Hydroxyapatite Coated with Arthemisia absinthium Composites
et Dorin Valter Enache Daniela Predoi There is significant research showing that essential oils extracted from the plants have antibacterial effects. The purpose of this study was to develop a biocomposite based on hydroxyapatite coated with Artemisia absinthium essential oil and to highlight its antibacterial activity. Therefore, present studies are aimed at developing new materials combining hydroxyapatite with Artemisia absinthium essential oil, in order to avoid postoperative infections. The purpose of this work is to highlight the antimicrobial properties of the Artemisia absinthium essential oil-hydroxyapatit...
Source: Molecules - January 19, 2020 Category: Chemistry Authors: Mariana Stefania Raita Simona Liliana Iconaru Andreea Groza Carmen Cimpeanu Gabriel Predoi Liliana Ghegoiu Monica Luminita Badea Mariana Carmen Chifiriuc Luminita Marutescu Roxana Trusca Ciprian Florin Furnaris Claudiu Stefan Turculet Dorin Valter Enache Tags: Article Source Type: research

Placebos can change affective contexts: an event-related potential study.
This study attempted to influence this context with a placebo. Sixty-eight women were randomly assigned to three groups: Water, Bitter/No-Placebo, Bitter/Placebo. Participants in the 'bitter groups' first rinsed their mouth with wormwood tea that caused a bitter aftertaste. Subsequently, the placebo group received sham light therapy on the tongue to 'reduce the sensitivity of the taste buds'. All groups viewed disgusting and non-disgusting pictures while their electroencephalogram was recorded. The Bitter/Placebo group reported reduced bitterness and disgust for the aftertaste after the sham treatment. The LPP reduction (3...
Source: Biological Psychology - January 13, 2020 Category: Psychiatry & Psychology Authors: Schienle A, Gremsl A, Schwab D Tags: Biol Psychol Source Type: research

Essential oil composition of five Artemisia (Compositae) species in regards to chemophenetics
Publication date: December 2019Source: Biochemical Systematics and Ecology, Volume 87Author(s): Pedja Janaćković, Nemanja Rajčević, Milan Gavrilović, Jelica Novaković, Abdulhmid Giweli, Danijela Stešević, Petar D. MarinAbstractIn this work we analysed the essential oils (EO) obtained by hydrodistillation from the aerial parts of five Artemisia species (A. arborescens L., A. campestris L., A. lobelii All., A. annua L. and A. absinthium L.) originated from Serbia, Montenegro, and Libya, by gas chromatography coupled with mass spectrometry. In total, 126 compounds were detected, and 120 were identified. Even tho...
Source: Biochemical Systematics and Ecology - November 10, 2019 Category: Biochemistry Source Type: research

Medicinal plants and their uses recorded in the Archives of Latvian Folklore from the 19th century
ConclusionsOne hundred and fifty-two plant taxa mentioned in the records of Latvian folk medicine are not included in the European Union herbal monographs providing scientific information on the safety and efficacy and deserve further exploration as traditional herbal medicines.Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - November 10, 2019 Category: Drugs & Pharmacology Source Type: research

Therapeutic potential of Artemisia vulgaris: An insight into underlying immunological mechanisms.
Authors: Soon L, Ng PQ, Chellian J, Madheswaran T, Panneerselvam J, Gupta G, Nammi S, Hansbro NG, Hsu A, Dureja H, Mehta M, Satija S, Hansbro PM, Dua K, Collet T, Chellappan DK Abstract Artemisia vulgaris is a traditional Chinese herb believed to have a wide range of healing properties; it is traditionally used to treat numerous health ailments. The plant is commonly called mugwort or riverside wormwood. The plant is edible, and in addition to its medicinal properties, it is also used as a culinary herb in Asian cooking in the form of a vegetable or in soup. The plant has garnered the attention of researchers in th...
Source: Journal of Environmental Pathology, Toxicology and Oncology - November 5, 2019 Category: Environmental Health Tags: J Environ Pathol Toxicol Oncol Source Type: research

Phytochemical composition of wormwood (Artemisia gmelinii) extracts in respect of their antimicrobial activity
This study aimed to evaluate the antimicrobia... (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - October 28, 2019 Category: Complementary Medicine Authors: Aliya S. Mamatova, Izabela Korona-Glowniak, Krystyna Skalicka-Wo źniak, Aleksandra Józefczyk, Krzysztof K. Wojtanowski, Tomasz Baj, Zuriyadda B. Sakipova and Anna Malm Tags: Research article Source Type: research

Synergistic antibacterial effects of Moroccan Artemisia herba alba, Lavandula angustifolia and Rosmarinus officinalis essential oils
ConclusionsThese results indicate a synergism for the combination of lavender, wormwood and rosemary essential oils at very low concentrations compared to MICs.Graphical abstract (Source: Synergy)
Source: Synergy - October 25, 2019 Category: Molecular Biology Source Type: research

Genetic resources of Tunisian Artemisia arborescens L. (Asteraceae), pattern of volatile metabolites concentration and bioactivity and implication for conservation
Publication date: December 2019Source: Biochemical Systematics and Ecology, Volume 87Author(s): Leila Riahi, Hnia Chograni, Ahmed Slaheddine Masmoudi, Ameur CherifAbstractArtemisia arborescens L. (Asteraceae) is an endemic and a valuable medicinal and ornamental species in the Mediterranean regions. Despite the interest given to A. arborescens L. as promising medicinal crop, this species is becoming threatened of extinction in Tunisia as a result of the fragmentation of its habitat and the absence of any specific measures for its conservation and valorisation. Based on the last considerations, extent information about thei...
Source: Biochemical Systematics and Ecology - September 27, 2019 Category: Biochemistry Source Type: research

Molecules, Vol. 24, Pages 3087: Romanian Wormwood (Artemisia absinthium L.): Physicochemical and Nutraceutical Screening
Szuhanek Dehelean Artemisia species are used worldwide for their antioxidant, antimicrobial and anti-inflammatory properties. This research was designed to investigate the phytochemical profile of two ethanolic extracts obtained from leaves and stems of A. absinthium L. as well as the biological potential (antioxidant activity, cytotoxic, anti-migratory and anti-inflammatory properties). Both plant materials showed quite similar thermogravimetric, FT-IR phenolic profile (high chlorogenic acid) with mild antioxidant capacity [ascorbic acid (0.02–0.1) > leaves (0.1–2.0) &...
Source: Molecules - August 25, 2019 Category: Chemistry Authors: Moac ă Pavel Danciu Cr ăiniceanu Minda Ardelean Antal Ghiulai Cioca Derban Simu Chioiba ş Szuhanek Dehelean Tags: Article Source Type: research

Chloroplast genome sequences of Artemisia maritima and Artemisia absinthium: Comparative analyses, mutational hotspots in genus Artemisia and phylogeny in family Asteraceae.
We report chloroplast genome sequences of two further Artemisia species: A. maritima (151,061 bp) and A. absinthium (151,193 bp). Both genomes possess typical quadripartite structure comprising of a large single copy, a small single copy and a pair of long inverted repeats. The two genomes exhibited high similarities in genome sizes, gene synteny, GC content, synonymous and non-synonymous substitutions, codon usage, amino acids frequencies, RNA editing sites, microsatellites, and oligonucleotide repeats. Transition to transversion ratio was
Source: Genomics - August 23, 2019 Category: Genetics & Stem Cells Authors: Shahzadi I, Abdullah, Mehmood F, Ali Z, Ahmed I, Mirza B Tags: Genomics Source Type: research

Non volatile constituents of the vermouth ingredient Artemisia vallesiaca.
Abstract The Alpine wormwood Artemisia vallesiaca All. was considered the most valuable ingredient of vermouth, a celebrated aromatized wine. A. vallesiaca has a very limited geographical distribution, and the booming market of vermouth decimated its natural population, resulting in the eventual replacement of this rare species with more common and less expensive wormwoods like A. absinthium L.. Over the past years, attempts to revive the original recipe(s) of vermouth have fostered the establishment of cultivations of A. vallesiaca in pre-montane settings. In order to assist these projects, the phytochemical prof...
Source: Fitoterapia - August 13, 2019 Category: Biochemistry Authors: Pollastro F, Lopatriello A, Vouillamoz JF, Appendino G, Taglialatela-Scafati O, Forino M Tags: Fitoterapia Source Type: research

Tools to improve referrals from primary care to specialty care.
CONCLUSIONS: Well-designed referral templates may help improve the clarity and completeness of primary care-specialty care referrals. Existing templates may provide models that can be adapted in collaboration with primary care and broadly applied to improve referrals. Work is needed to improve the impact of service agreements and e-consults on referrals. PMID: 31419100 [PubMed - in process] (Source: The American Journal of Managed Care)
Source: The American Journal of Managed Care - August 1, 2019 Category: Health Management Authors: Vimalananda VG, Meterko M, Waring ME, Qian S, Solch A, Wormwood JB, Fincke BG Tags: Am J Manag Care Source Type: research

Protein Biomarkers in Major Depressive Disorder: An Update.
Authors: Woods AG, Wormwood KL, Iosifescu DV, Murrough J, Darie CC Abstract Major depressive disorder (MDD) is common. Despite numerous available treatments, many individuals fail to improve clinically. Diagnosis of MDD continues to be commonly accomplished via behavioral rather than biological methods. Biomarkers may provide objective diagnosis of MDD, and could include measurements of genes, proteins, and patterns of brain activity. Proteomic analysis and validation of biomarkers is less explored than other areas of biomarker research in MDD. Mass spectrometry (MS) is a comprehensive, unbiased means of proteomic ...
Source: Advances in Experimental Medicine and Biology - July 29, 2019 Category: Research Tags: Adv Exp Med Biol Source Type: research

Mass Spectrometry for the  Study of Autism and Neurodevelopmental Disorders.
Mass Spectrometry for the Study of Autism and Neurodevelopmental Disorders. Adv Exp Med Biol. 2019;1140:477-499 Authors: Wormwood KL, Ngounou Wetie AG, Ryan JP, Darie CC, Woods AG Abstract Mass spectrometry (MS) has been increasingly used to study central nervous system (CNS) disorders, including autism spectrum disorders (ASDs). The first studies of ASD using MS focused on the identification of external toxins, but current research is more directed at understanding endogenous protein changes that occur in ASD (ASD proteomics). This chapter focuses on how MS has been used to study ASDs, with parti...
Source: Advances in Experimental Medicine and Biology - July 29, 2019 Category: Research Tags: Adv Exp Med Biol Source Type: research

The Potential for Ion Mobility in Pharmaceutical and Clinical Analyses.
Authors: Wormwood KL, Deng L, Hamid AM, DeBord D, Maxon L Abstract The pharmaceutical and clinical industries are imperative for the maintenance of global health and welfare and require accurate, reproducible, and high throughput analyses. Technological advancements, such as the development and implementation of liquid chromatography-tandem mass spectrometry (LC-MS), have allowed for improvements in these areas, however there is still room for development. One way in which current analyses may be improved is by the implementation of ion mobility technology. Ion mobility has the capability to produce much more compr...
Source: Advances in Experimental Medicine and Biology - July 29, 2019 Category: Research Tags: Adv Exp Med Biol Source Type: research

Mass Spectrometry- and Computational Structural Biology-Based Investigation of Proteins and Peptides.
Authors: Mihăşan M, Wormwood KL, Sokolowska I, Roy U, Woods AG, Darie CC Abstract Recent developments of mass spectrometry (MS) allow us to identify, estimate, and characterize proteins and protein complexes. At the same time, structural biology helps to determine the protein structure and its structure-function relationship. Together, they aid to understand the protein structure, property, function, protein-complex assembly, protein-protein interaction, and dynamics. The present chapter is organized with illustrative results to demonstrate how experimental mass spectrometry can be combined with computational str...
Source: Advances in Experimental Medicine and Biology - July 29, 2019 Category: Research Tags: Adv Exp Med Biol Source Type: research

Identification of Posttranslational Modifications (PTMs) of Proteins by  Mass Spectrometry.
Identification of Posttranslational Modifications (PTMs) of Proteins by Mass Spectrometry. Adv Exp Med Biol. 2019;1140:199-224 Authors: Aslebagh R, Wormwood KL, Channaveerappa D, Wetie AGN, Woods AG, Darie CC Abstract There are only 30,000 human genes, which, according to the central dogma from biology, it means that there should be 30,000 mRNA and 30,000 proteins. However, there are at least 1-2 million protein entities that are expressed in a cell at a given time. This is primarily due to alternative splicing in different cells and tissues, which may lead to expression of different protein isofo...
Source: Advances in Experimental Medicine and Biology - July 29, 2019 Category: Research Tags: Adv Exp Med Biol Source Type: research

Mass Spectrometry for Proteomics-Based Investigation.
Authors: Woods AG, Sokolowska I, Ngounou Wetie AG, Channaveerappa D, Dupree EJ, Jayathirtha M, Aslebagh R, Wormwood KL, Darie CC Abstract Within the past years, we have witnessed a great improvement is mass spectrometry (MS) and proteomics approaches in terms of instrumentation, protein fractionation, and bioinformatics. With the current technology, protein identification alone is no longer sufficient. Both scientists and clinicians want not only to identify the proteins, but also to identify the protein's post-translational modifications (PTMs), protein isoforms, protein truncation, protein-protein interactions (P...
Source: Advances in Experimental Medicine and Biology - July 29, 2019 Category: Research Tags: Adv Exp Med Biol Source Type: research

Ethnobotanical Study of Cultivated Plants in Kai šiadorys District, Lithuania: Possible Trends for New Herbal Based Medicines.
Conclusions: Only 19 of the cultivated medicinal plant species mentioned by interviewed persons are described in the World Health Organization monographs. This means that the remaining 52 species are used without the World Health Organization approved medical indications, based solely on the folk medicine knowledge and experience. This study showed that the folk use of plants is strongly rooted in daily practice in the studied area. PMID: 31239859 [PubMed] (Source: Evidence-based Complementary and Alternative Medicine)
Source: Evidence-based Complementary and Alternative Medicine - June 27, 2019 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research

Principles of Allergen Immunotherapy and Its Clinical Application in China: Contrasts and Comparisons with the USA
AbstractAllergen immunotherapy (AIT) for allergic rhinitis (AR), asthma, and other allergic diseases has developed quickly. House dust mite (HDM),Artemisia (wormwood),Humulus japonicus (Japanese hop),Alternaria alternata, andCladosporium herbarum are the five most common inhalant allergens in China. AIT has been performed in China for over 60  years. With the support of the Chinese Medical Association (CMA) and the Chinese Medical Doctors Association (CMDA), the Chinese College of Allergy and Asthma (CCAA) was established in 2016 as a specialized branch of CDMA and is the main certification authority for AIT. Chinese ...
Source: Clinical Reviews in Allergy and Immunology - June 26, 2019 Category: Allergy & Immunology Source Type: research

Development of a PCR High-Resolution Melt Assay for Artemisia absinthium (Wormwood) and a Triplex Assay with Two Additional "Unregulated Legal High" Species Datura stramonium (Jimson Weed) and Merremia tuberosa (Hawaiian Woodrose).
This study developed a polymerase chain reaction (PCR) high-resolution melt (HRM) assay to detect and identify A. absinthium based on primer specificity, sensitivity, repeatability, and robustness. A triplex assay was performed with three "unregulated legal high" species: Datura stramonium, Merremia tuberosa, and A. absinthium; the PCR HRM assay detected and identified each plant at melt temperatures 77.42 ± 0.20°C, 83.88 ± 0.22°C, and 87.77 ± 0.15°C, respectively. The primer set developed distinguished A. absinthium from a variety of p...
Source: Journal of Forensic Sciences - June 3, 2019 Category: Forensic Medicine Authors: Kiesel BD, Elkins KM Tags: J Forensic Sci Source Type: research

Intervention of artemisinin in macular edema associated with retinal vein occlusion: A protocol for a systematic review and meta-analysis
Background: Artemisinin was discovered to be highly effective antimalarial drugs shortly after the isolation of the parent artemisinin in 1971 in China. It is derived from extracts of sweet wormwood (Artemisia annua) and are well established for the treatment of malaria. Recently, artemisinin has been shown that it might have therapeutic value for several other diseases. The purpose of this review is to assess the efficacy of artemisinin as a treatment for macular edema associated with retinal vein occlusion. Methods and analysis: A systematic literature search will be performed in all available databases to quantitat...
Source: Medicine - June 1, 2019 Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research

Supercritical anti-solvent fractionation of Artemisia absinthium L. conventional extracts: tracking artemetin and casticin
Publication date: Available online 7 May 2019Source: The Journal of Supercritical FluidsAuthor(s): Elisa Langa, Juan I. Pardo, Carlota Giménez-Rota, Azucena González-Coloma, María J. Hernáiz, Ana M. MainarAbstractIn the current work the Supercritical Anti-solvent Fractionation (SAF) methodology was applied to conventional extracts from Artemisia absinthium L. (wormwood). Artemetin and casticin, two compounds found in wormwood extracts and with high structural similarity, were tracked in all the experiments. A Response Surface Methodology (RSM), based on Central Composite Design (CCD) was used fo...
Source: The Journal of Supercritical Fluids - May 8, 2019 Category: Chemistry Source Type: research

Methyl 3-(5-(prop-1-yn-1-yl)thiophen-2-yl)propanoate: A Rare Acetylene Derivative from Artemisia absinthium Root Essential Oil.
Authors: Polina D B, Marko S P, Niko S R Abstract Methyl 3-(5-(prop-l-yn-l-yl)thiophen-2-yl)propanoate (1), biosynthetically and structurally related to dehydromatricaria ester, was isolated from the root essential oil of Artemisia absinthium L. (0.7% of the total oil). This is the second record of this compound and the very first one regarding it as an essential-oil constituent. In this paper, we give details regarding its isolation, structural elucidation and gas chromatographic properties (RI on DB-5 MS column: 1694). The NMR-based identification of the compound was corroborated by simulation of its 'H- and &quo...
Source: Natural Product Communications - March 30, 2019 Category: Biochemistry Tags: Nat Prod Commun Source Type: research

Molecules, Vol. 24, Pages 913: The Extracts of Artemisia absinthium L. Suppress the Growth of Hepatocellular Carcinoma Cells through Induction of Apoptosis via Endoplasmic Reticulum Stress and Mitochondrial-Dependent Pathway
iu Xu Li Artemisia absinthium L. has pharmaceutical and medicinal effects such as antimicrobial, antiparasitic, hepatoprotective, and antioxidant activities. Here, we prepared A. absinthium ethanol extract (AAEE) and its subfractions including petroleum ether (AAEE-Pe) and ethyl acetate (AAEE-Ea) and investigated their antitumor effect on human hepatoma BEL-7404 cells and mouse hepatoma H22 cells. The cell viability of hepatoma cells was measured by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The apoptosis, cell cycle, mitochondrial membrane potential (Δψm)...
Source: Molecules - March 5, 2019 Category: Chemistry Authors: Wei Xia Ziyayiding Chen Liu Xu Li Tags: Article Source Type: research

The anti-malarial drug artesunate causes cell cycle arrest and apoptosis of triple-negative MDA-MB-468 and HER2-enriched SK-BR-3 breast cancer cells.
In this study, we demonstrate a dose- and time-dependent inhibitory effect of ART on the growth of triple-negative MDA-MB-468 and HER2-enriched SK-BR-3 breast cancer cells, which was the result of both anti-proliferative and cytotoxic activities. ART inhibited breast cancer cell proliferation via a reactive oxygen species (ROS)-dependent G2/M arrest and ROS-independent G1 arrest. ART-treated MDA-MB-468 and SK-BR-3 cells also experienced apoptotic cell death, which was both ROS- and iron-dependent. ART-induced oxidative stress caused the loss of mitochondrial outer membrane integrity and damage to the cellular DNA of MDA-MB...
Source: Experimental and Molecular Pathology - January 17, 2019 Category: Pathology Authors: Greenshields AL, Fernando W, Hoskin DW Tags: Exp Mol Pathol Source Type: research

The Use of Traditional and Complementary Medicine for Diabetes in Rural Guatemala.
CONCLUSION: There is widespread use of medicinal plants in San Lucas Tolimán. More research is needed to understand the degree of glycemic control in these communities. PMID: 30449743 [PubMed - in process] (Source: Journal of Health Care for the Poor and Underserved)
Source: Journal of Health Care for the Poor and Underserved - November 21, 2018 Category: International Medicine & Public Health Authors: Andrews CM, Wyne K, Svenson JE Tags: J Health Care Poor Underserved Source Type: research

An insight into chemical composition and bioactivity of 'Prokupac' red wine.
ć ML Abstract Autochthonous variety 'Prokupac' (Vitis vinifera L.) red wines with the addition of selected aromatic herbs (Artemisia absinthium, Cinnamomum zeylanicum, Glycyrrhiza glabra and Pimpinella anisum L.) were evaluated for chemical composition and biological activity. Furthermore, their polyphenolic profiles were determined by HPLC-DAD. While total phenolic (TPC) and flavonoid (TFC) contents, along with antioxidant activity, were significantly higher in all examined wine samples, the content of total anthocyanins was decreased, compared to a pure 'Prokupac' wine, used as the control one. On the other han...
Source: Natural Product Research - November 16, 2018 Category: Biochemistry Authors: Lakićević SH, Popović Djordjević JB, Pejin B, Djordjević AS, Matijašević SM, Lazić ML Tags: Nat Prod Res Source Type: research

Ovicidal and larvicidal activity of extracts from medicinal-plants against Haemonchus contortus.
idayová S, Königová A, Vadlejch J, Várady M Abstract The use of medicinal plants (MP) containing bioactive compounds is an alternative strategy to control of parasitic nematode of small ruminants Haemonchus contortus at various stages of their life cycle. The aims of this study were to determine the in vitro anthelmintic activity of both aqueous and methanolic extracts from 13 medicinal plants typical for Central Europe, and to determine quantity of selected plant secondary metabolites (PSMs) in the methanolic extracts. In vitro egg hatch test and larval development tests were conducted t...
Source: Experimental Parasitology - October 30, 2018 Category: Parasitology Authors: Váradyová Z, Pisarčíková J, Babják M, Hodges A, Mravčáková D, Kišidayová S, Königová A, Vadlejch J, Várady M Tags: Exp Parasitol Source Type: research

Effect of Artemisia annua and Artemisia afra tea infusions on schistosomiasis in a large clinical trial.
ConclusionBoth A. annua and A. afra provided faster effective treatment of schistosomiasis and should be considered for implementation on a global scale.Graphical abstract (Source: Phytomedicine)
Source: Phytomedicine - October 12, 2018 Category: Drugs & Pharmacology Source Type: research

Hypolipidemic effect of SIPI-7623, a derivative of an extract from oriental wormwood, through farnesoid X receptor antagonism
In conclusion, SIPI-7623 could be a promising lead compound for development of drugs to treat hyperlipidemia and atherosclerosis. (Source: Chinese Journal of Natural Medicines)
Source: Chinese Journal of Natural Medicines - September 8, 2018 Category: Complementary Medicine Source Type: research

Chicory (Cichorium intybus) and wormwood (Artemisia absinthium) extracts exhibit strong larvicidal activity against mosquito vectors of malaria, dengue fever, and filariasis
Publication date: Available online 14 August 2018Source: Parasitology InternationalAuthor(s): Sofi Imtiyaz Ali, B. Gopalakrishnan, V. VenkatesaluAbstractVector-borne diseases transmitted by mosquitoes cause globally important diseases such as malaria, dengue fever, and filariasis. The incidence of these diseases can be reduced through mosquito control programs but these control programs currently rely on synthetic insecticides that can impact the environment, and has selected widespread mosquito resistance. Environment friendly and biodegradable natural insecticides discovered in plants offer an alternative approach to mos...
Source: Parasitology International - August 16, 2018 Category: Parasitology Source Type: research

Conscious awareness is necessary for affective faces to influence social judgments
Publication date: November 2018Source: Journal of Experimental Social Psychology, Volume 79Author(s): Ian R. Kleckner, Eric C. Anderson, Nicole J. Betz, Jolie B. Wormwood, Rhea T. Eskew, Lisa Feldman BarrettAbstractA growing body of research claims that stimuli presented outside conscious awareness can influence affect, speech perception, decision-making, eating behavior, and social judgments. However, research has shown that conscious awareness is a continuous phenomenon. Using a continuous flash suppression (CFS) paradigm to suppress awareness of affective faces (smiling and scowling), we demonstrate that some awareness ...
Source: Journal of Experimental Social Psychology - August 4, 2018 Category: Psychiatry & Psychology Source Type: research

Vegetarians’ and omnivores’ affective and physiological responses to images of food
We presented pictures of different food items and recorded participants’ affective experience while we recorded peripheral physiology. We found that vegetarians’ self-reported experience of meat meal images was less pleasant than omnivores’, but that other food images were equally pleasant across the two groups. Moreover, vegetarians and omnivores had strikingly similar physiological responses to all food images – including meat meals. We interpret these results from a psychological constructionist perspective, which posits that individuals conceptualize changes in their bodily states in ways that m...
Source: Food Quality and Preference - July 11, 2018 Category: Food Science Source Type: research

Effects of temperature and light intensity on morphological and phytochemical characters and antioxidant potential of wormwood (Artemisia absinthium L.)
Publication date: August 2018Source: Biochemical Systematics and Ecology, Volume 79Author(s): Huong Thi Nguyen, Péter Radácsi, Beáta Gosztola, Éva Zámboriné NémethAbstractThe effect of temperature and light intensity on the growth and the production of active ingredients of Artemisia absinthium L. was studied. To this purpose, young plants of two wormwood accessions with different geographical origin were grown for 14 weeks in climatic chambers under two controlled conditions identified as "warm" and "cold", respectively. Both the tested environments (war...
Source: Biochemical Systematics and Ecology - July 11, 2018 Category: Biochemistry Source Type: research

The activity of Artemisia spp. and their constituents against Trypanosomasis
ConclusionThere are numerous results reporting on the anti-trypanosomal activity the genus Artemisia, artemisinin and its derivatives and other phytochemicals from Artemisia species. This field of research is, however, still in its infancy and more intensive research is required to explore the full potential of diverse Artemisia species and their chemical ingredients for eradication of trypanosomal infections.Graphical abstract (Source: Phytomedicine)
Source: Phytomedicine - July 10, 2018 Category: Drugs & Pharmacology Source Type: research

Effects of temperature and light intensity on morphological and phytochemical characters and antioxidant potential of wormwood (Artemisia absinthium L.)
Publication date: August 2018Source: Biochemical Systematics and Ecology, Volume 79Author(s): Huong Thi Nguyen, Péter Radácsi, Beáta Gosztola, Éva Zámboriné NémethAbstractThe effect of temperature and light intensity on the growth and the production of active ingredients of Artemisia absinthium L. was studied. To this purpose, young plants of two wormwood accessions with different geographical origin were grown for 14 weeks in climatic chambers under two controlled conditions identified as "warm" and "cold", respectively. Both the tested environments (war...
Source: Biochemical Systematics and Ecology - July 6, 2018 Category: Biochemistry Source Type: research

The activity of Artemisia spp. and their constituents against Trypanosomasis
ConclusionThere are numerous results reporting on the anti-trypanosomal activity the genus Artemisia, artemisinin and its derivatives and other phytochemicals from Artemisia species. This field of research is, however, still in its infancy and more intensive research is required to explore the full potential of diverse Artemisia species and their chemical ingredients for eradication of trypanosomal infections.Graphical abstract (Source: Phytomedicine)
Source: Phytomedicine - July 5, 2018 Category: Drugs & Pharmacology Source Type: research

Vegetarians’ and omnivores’ affective and physiological responses to images of food
We presented pictures of different food items and recorded participants’ affective experience while we recorded peripheral physiology. We found that vegetarians’ self-reported experience of meat meal images was less pleasant than omnivores’, but that other food images were equally pleasant across the two groups. Moreover, vegetarians and omnivores had strikingly similar physiological responses to all food images – including meat meals. We interpret these results from a psychological constructionist perspective, which posits that individuals conceptualize changes in their bodily states in ways that m...
Source: Food Quality and Preference - July 5, 2018 Category: Food Science Source Type: research

Vegetarians ’ and omnivores’ affective and physiological responses to images of food
We presented pictures of different food items and recorded participants’ affective experience while we recorded peripheral physiology. We found that vegetarians’ self-reported experience of meat meal images was less pleasant than omnivores’, but that other food images were equally pleasant across the two groups. Moreover, vegetarians and omnivores had strikingly similar physiological responses to all food images – including meat meals. We interpret these results from a psychological constructionist perspective, which posits that individuals conceptualize changes in their bodily states in ways that m...
Source: Food Quality and Preference - July 2, 2018 Category: Food Science Source Type: research

The activity of Artemisia spp. and their constituents against Trypanosomasis
Conclusion There are numerous results reporting on the anti-trypanosomal activity the genus Artemisia, artemisinin and its derivatives and other phytochemicals from Artemisia species. This field of research is, however, still in its infancy and more intensive research is required to explore the full potential of diverse Artemisia species and their chemical ingredients for eradication of trypanosomal infections. Graphical abstract (Source: Phytomedicine)
Source: Phytomedicine - June 10, 2018 Category: Drugs & Pharmacology Source Type: research

Effects of temperature and light intensity on morphological and phytochemical characters and antioxidant potential of wormwood (Artemisia absinthium L.)
Publication date: August 2018 Source:Biochemical Systematics and Ecology, Volume 79 Author(s): Huong Thi Nguyen, Péter Radácsi, Beáta Gosztola, Éva Zámboriné Németh The effect of temperature and light intensity on the growth and the production of active ingredients of Artemisia absinthium L. was studied. To this purpose, young plants of two wormwood accessions with different geographical origin were grown for 14 weeks in climatic chambers under two controlled conditions identified as "warm" and "cold", respectively. Both the tested environments (warm, wi...
Source: Biochemical Systematics and Ecology - June 5, 2018 Category: Biochemistry Source Type: research

Hemato-biochemcial characteristics of lambs on dietary feed additives (exogenous fibrolytic enzymes, Artemisia absinthium Linn.) supplementation
AbstractDietary composition affects blood metabolic profile of farm animals. Hemato-biochemical indices serve as clinical indicators for the impact of dietary manipulations on physiological health status. To augment sheep productivity in temperate regions by improving animal health conditions, the present study was undertaken to assess the effect of supplementation of exogenous fibrolytic enzymes (EFE) cocktail andArtemisia absinthium L. (commonly known as wormwood) herb alone and in combination as feed additives on blood metabolic profile in lambs. Crossbred lambs (n = 20) divided into four equal groups of f...
Source: Comparative Clinical Pathology - May 31, 2018 Category: Pathology Source Type: research

Prevention of carcinogenesis and metastasis by Artemisinin-type drugs
Artemisia annua (sweet wormwood, qinhao) is an ancient Chinese herbal remedy for pyrexia. Nowadays, artemisinin (qinghaosu) and its derivatives belong to the standard therapies against malaria worldwide, and its discovery has led to the Nobel Prize in Physiology and Medicine to Youyou Tu in 2015. While most attention has been paid to the treatment of malaria, there is increasing evidence that Artemisinin-type drugs bear a considerable potential to treat and prevent cancer. Rather than reporting on therapy of cancer, this review gives a comprehensive and timely overview on the chemopreventive effects of artemisinin and its ...
Source: Cancer Letters - May 7, 2018 Category: Cancer & Oncology Authors: Mohammed L. Abba, Nitin Patil, J örg Hendrik Leupold, Mohamed E.M. Saeed, Thomas Efferth, Heike Allgayer Tags: Original Articles Source Type: research

Mechanisms of the pH- and Oxygen-Dependent Oxidation Activities of Artesunate.
Abstract Artemisinin was discovered in 1971 as a constituent of the wormwood genus plant (Artemisia annua). This plant has been used as an herbal medicine to treat malaria since ancient times. The compound artemisinin has a sesquiterpene lactone bearing a peroxide group that offers its biological activity. In addition to anti-malarial activity, artemisinin derivatives have been reported to exert antitumor activity in cancer cells, and have attracted attention as potential anti-cancer drugs. Mechanisms that might explain the antitumor activities of artemisinin derivatives reportedly induction of apoptosis, angiogen...
Source: Biological and Pharmaceutical Bulletin - April 4, 2018 Category: Drugs & Pharmacology Authors: Tsuda K, Miyamoto L, Hamano S, Morimoto Y, Kangawa Y, Fukue C, Kagawa Y, Horinouchi Y, Xu W, Ikeda Y, Tamaki T, Tsuchiya K Tags: Biol Pharm Bull Source Type: research

Evaluation of anticancer, antioxidant activity and phenolic compounds of Artemisia absinthium  L. Extract.
This study aimed to examine the anti-cancer and antioxidant properties and identify the phenolic content of the methanolic extract obtained from Artemisia absinthium L. (AR) species, which is used as folk-medicine. The antioxidant activity of the extract was investigated using total phenolics, flavonoids, ABTS and CUPRAC methods. Phenolic component analysis of the plant extract was performed by LC-MS/MS. The anti-cancer property of AR extract was investigated on human colon (DLD-1), endometrium (ECC-1) cancer cells and embryonic kidney (HEK-293) cells. Cytotoxic effects were defined with MTT, apoptotic activity with DNA fr...
Source: Cellular and Molecular Biology - March 8, 2018 Category: Molecular Biology Tags: Cell Mol Biol (Noisy-le-grand) Source Type: research

Chemical composition and antifungal activity of plant extracts traditionally used in organic and biodynamic farming.
Abstract Five plant extracts traditionally used in organic and biodynamic farming for pest control and antifungal (downy mildew) disease management were selected after a farmer survey and analyzed for their chemical composition in LC-PDA-MS-MS and using adapted analytical method from food chemistry for determination of class of component (e.g., protein, sugar, lipids…). Their antifungal activity against Penicillium expansum, Botrytis cinerea, Botrytis allii, brown rot causing agents (Monilinia laxa and Monilinia fructigena), and grape downy mildew (Plasmopara viticola) was examined in vitro. White willow (S...
Source: Environmental Science and Pollution Research International - March 7, 2018 Category: Environmental Health Authors: Andreu V, Levert A, Amiot A, Cousin A, Aveline N, Bertrand C Tags: Environ Sci Pollut Res Int Source Type: research

83PArtemisia absinthium extract loaded polymeric nanoparticles as the therapeutic remedy for breast cancer
Background: Besides significant progress in the field of cancer therapy, breast cancer remains the major ongoing health problem among the women worldwide because of the side effects of available drugs. This problem can be overcome by loading herbal extract into the polymeric nanoparticles that will aid in site-specific drug delivery and increase in the retention time of drug, thereby improving therapeutic efficacy. (Source: Annals of Oncology)
Source: Annals of Oncology - March 5, 2018 Category: Cancer & Oncology Source Type: research