Hypolipidemic effect of SIPI-7623, a derivative of an extract from oriental wormwood, through farnesoid X receptor antagonism
In conclusion, SIPI-7623 could be a promising lead compound for development of drugs to treat hyperlipidemia and atherosclerosis. (Source: Chinese Journal of Natural Medicines)
Source: Chinese Journal of Natural Medicines - September 7, 2018 Category: Complementary Medicine Source Type: research
Chicory (Cichorium intybus) and wormwood (Artemisia absinthium) extracts exhibit strong larvicidal activity against mosquito vectors of malaria, dengue fever, and filariasis
Publication date: Available online 14 August 2018Source: Parasitology InternationalAuthor(s): Sofi Imtiyaz Ali, B. Gopalakrishnan, V. VenkatesaluAbstractVector-borne diseases transmitted by mosquitoes cause globally important diseases such as malaria, dengue fever, and filariasis. The incidence of these diseases can be reduced through mosquito control programs but these control programs currently rely on synthetic insecticides that can impact the environment, and has selected widespread mosquito resistance. Environment friendly and biodegradable natural insecticides discovered in plants offer an alternative approach to mos...
Source: Parasitology International - August 16, 2018 Category: Parasitology Source Type: research
Conscious awareness is necessary for affective faces to influence social judgments
Publication date: November 2018Source: Journal of Experimental Social Psychology, Volume 79Author(s): Ian R. Kleckner, Eric C. Anderson, Nicole J. Betz, Jolie B. Wormwood, Rhea T. Eskew, Lisa Feldman BarrettAbstractA growing body of research claims that stimuli presented outside conscious awareness can influence affect, speech perception, decision-making, eating behavior, and social judgments. However, research has shown that conscious awareness is a continuous phenomenon. Using a continuous flash suppression (CFS) paradigm to suppress awareness of affective faces (smiling and scowling), we demonstrate that some awareness ...
Source: Journal of Experimental Social Psychology - August 4, 2018 Category: Psychiatry & Psychology Source Type: research
Vegetarians’ and omnivores’ affective and physiological responses to images of food
We presented pictures of different food items and recorded participants’ affective experience while we recorded peripheral physiology. We found that vegetarians’ self-reported experience of meat meal images was less pleasant than omnivores’, but that other food images were equally pleasant across the two groups. Moreover, vegetarians and omnivores had strikingly similar physiological responses to all food images – including meat meals. We interpret these results from a psychological constructionist perspective, which posits that individuals conceptualize changes in their bodily states in ways that match their belie...
Source: Food Quality and Preference - July 11, 2018 Category: Food Science Source Type: research
Effects of temperature and light intensity on morphological and phytochemical characters and antioxidant potential of wormwood (Artemisia absinthium L.)
Publication date: August 2018Source: Biochemical Systematics and Ecology, Volume 79Author(s): Huong Thi Nguyen, Péter Radácsi, Beáta Gosztola, Éva Zámboriné NémethAbstractThe effect of temperature and light intensity on the growth and the production of active ingredients of Artemisia absinthium L. was studied. To this purpose, young plants of two wormwood accessions with different geographical origin were grown for 14 weeks in climatic chambers under two controlled conditions identified as "warm" and "cold", respectively. Both the tested environments (warm, with temperature from 18 °C/10 °C to 27 °C/19 °...
Source: Biochemical Systematics and Ecology - July 11, 2018 Category: Biochemistry Source Type: research
The activity of Artemisia spp. and their constituents against Trypanosomasis
ConclusionThere are numerous results reporting on the anti-trypanosomal activity the genus Artemisia, artemisinin and its derivatives and other phytochemicals from Artemisia species. This field of research is, however, still in its infancy and more intensive research is required to explore the full potential of diverse Artemisia species and their chemical ingredients for eradication of trypanosomal infections.Graphical abstract (Source: Phytomedicine)
Source: Phytomedicine - July 10, 2018 Category: Drugs & Pharmacology Source Type: research
Effects of temperature and light intensity on morphological and phytochemical characters and antioxidant potential of wormwood (Artemisia absinthium L.)
Publication date: August 2018Source: Biochemical Systematics and Ecology, Volume 79Author(s): Huong Thi Nguyen, Péter Radácsi, Beáta Gosztola, Éva Zámboriné NémethAbstractThe effect of temperature and light intensity on the growth and the production of active ingredients of Artemisia absinthium L. was studied. To this purpose, young plants of two wormwood accessions with different geographical origin were grown for 14 weeks in climatic chambers under two controlled conditions identified as "warm" and "cold", respectively. Both the tested environments (warm, with temperature from 18 °C/10 °C to 27 °C/19 °...
Source: Biochemical Systematics and Ecology - July 5, 2018 Category: Biochemistry Source Type: research
The activity of Artemisia spp. and their constituents against Trypanosomasis
ConclusionThere are numerous results reporting on the anti-trypanosomal activity the genus Artemisia, artemisinin and its derivatives and other phytochemicals from Artemisia species. This field of research is, however, still in its infancy and more intensive research is required to explore the full potential of diverse Artemisia species and their chemical ingredients for eradication of trypanosomal infections.Graphical abstract (Source: Phytomedicine)
Source: Phytomedicine - July 5, 2018 Category: Drugs & Pharmacology Source Type: research
Vegetarians’ and omnivores’ affective and physiological responses to images of food
We presented pictures of different food items and recorded participants’ affective experience while we recorded peripheral physiology. We found that vegetarians’ self-reported experience of meat meal images was less pleasant than omnivores’, but that other food images were equally pleasant across the two groups. Moreover, vegetarians and omnivores had strikingly similar physiological responses to all food images – including meat meals. We interpret these results from a psychological constructionist perspective, which posits that individuals conceptualize changes in their bodily states in ways that match their belie...
Source: Food Quality and Preference - July 5, 2018 Category: Food Science Source Type: research
Vegetarians ’ and omnivores’ affective and physiological responses to images of food
We presented pictures of different food items and recorded participants’ affective experience while we recorded peripheral physiology. We found that vegetarians’ self-reported experience of meat meal images was less pleasant than omnivores’, but that other food images were equally pleasant across the two groups. Moreover, vegetarians and omnivores had strikingly similar physiological responses to all food images – including meat meals. We interpret these results from a psychological constructionist perspective, which posits that individuals conceptualize changes in their bodily states in ways that match their belie...
Source: Food Quality and Preference - July 2, 2018 Category: Food Science Source Type: research
The activity of Artemisia spp. and their constituents against Trypanosomasis
Conclusion There are numerous results reporting on the anti-trypanosomal activity the genus Artemisia, artemisinin and its derivatives and other phytochemicals from Artemisia species. This field of research is, however, still in its infancy and more intensive research is required to explore the full potential of diverse Artemisia species and their chemical ingredients for eradication of trypanosomal infections. Graphical abstract (Source: Phytomedicine)
Source: Phytomedicine - June 10, 2018 Category: Drugs & Pharmacology Source Type: research
Effects of temperature and light intensity on morphological and phytochemical characters and antioxidant potential of wormwood (Artemisia absinthium L.)
Publication date: August 2018 Source:Biochemical Systematics and Ecology, Volume 79 Author(s): Huong Thi Nguyen, Péter Radácsi, Beáta Gosztola, Éva Zámboriné Németh The effect of temperature and light intensity on the growth and the production of active ingredients of Artemisia absinthium L. was studied. To this purpose, young plants of two wormwood accessions with different geographical origin were grown for 14 weeks in climatic chambers under two controlled conditions identified as "warm" and "cold", respectively. Both the tested environments (warm, with temperature from 18 °C/10 °C to 27 °C/19 °...
Source: Biochemical Systematics and Ecology - June 5, 2018 Category: Biochemistry Source Type: research
Hemato-biochemcial characteristics of lambs on dietary feed additives (exogenous fibrolytic enzymes, Artemisia absinthium Linn.) supplementation
AbstractDietary composition affects blood metabolic profile of farm animals. Hemato-biochemical indices serve as clinical indicators for the impact of dietary manipulations on physiological health status. To augment sheep productivity in temperate regions by improving animal health conditions, the present study was undertaken to assess the effect of supplementation of exogenous fibrolytic enzymes (EFE) cocktail andArtemisia absinthium L. (commonly known as wormwood) herb alone and in combination as feed additives on blood metabolic profile in lambs. Crossbred lambs (n = 20) divided into four equal groups of five in eac...
Source: Comparative Clinical Pathology - May 31, 2018 Category: Pathology Source Type: research
Prevention of carcinogenesis and metastasis by Artemisinin-type drugs
Artemisia annua (sweet wormwood, qinhao) is an ancient Chinese herbal remedy for pyrexia. Nowadays, artemisinin (qinghaosu) and its derivatives belong to the standard therapies against malaria worldwide, and its discovery has led to the Nobel Prize in Physiology and Medicine to Youyou Tu in 2015. While most attention has been paid to the treatment of malaria, there is increasing evidence that Artemisinin-type drugs bear a considerable potential to treat and prevent cancer. Rather than reporting on therapy of cancer, this review gives a comprehensive and timely overview on the chemopreventive effects of artemisinin and its ...
Source: Cancer Letters - May 7, 2018 Category: Cancer & Oncology Authors: Mohammed L. Abba, Nitin Patil, J örg Hendrik Leupold, Mohamed E.M. Saeed, Thomas Efferth, Heike Allgayer Tags: Original Articles Source Type: research
Mechanisms of the pH- and Oxygen-Dependent Oxidation Activities of Artesunate.
Abstract
Artemisinin was discovered in 1971 as a constituent of the wormwood genus plant (Artemisia annua). This plant has been used as an herbal medicine to treat malaria since ancient times. The compound artemisinin has a sesquiterpene lactone bearing a peroxide group that offers its biological activity. In addition to anti-malarial activity, artemisinin derivatives have been reported to exert antitumor activity in cancer cells, and have attracted attention as potential anti-cancer drugs. Mechanisms that might explain the antitumor activities of artemisinin derivatives reportedly induction of apoptosis, ...
Source: Biological and Pharmaceutical Bulletin - April 4, 2018 Category: Drugs & Pharmacology Authors: Tsuda K, Miyamoto L, Hamano S, Morimoto Y, Kangawa Y, Fukue C, Kagawa Y, Horinouchi Y, Xu W, Ikeda Y, Tamaki T, Tsuchiya K Tags: Biol Pharm Bull Source Type: research
