Assessment of Acupuncture and Moxibustion Effects on the Electrophysiological Properties of the Ulnar Nerve: A Nerve Conduction Study
Conclusions: Acupuncture and moxibustion on HT 4 increased the electrical sensitivity, decreased the stimulus intensity to achieve the maximum amplitude, and avoided a significant increase in latency and decrease in reaction velocity in two consecutive electrical stimulations.Integr Med Int 2018;4:198 –207 (Source: Integrative Medicine International)
Source: Integrative Medicine International - July 11, 2018 Category: Complementary Medicine Source Type: research

Effect of Antenatal Pelvic Floor Muscle Exercise on Mode of Delivery: A Randomized Controlled Trial
Conclusions: PFM exercise is recommended for healthy pregnant women as a safe and inexpensive strategy for increasing the vaginal delivery rate.Integr Med Int 2017;4:187 –197 (Source: Integrative Medicine International)
Source: Integrative Medicine International - April 25, 2018 Category: Complementary Medicine Source Type: research

Effect of a Residential Integrated Yoga Program on Blood Glucose Levels, Physiological Variables, and Anti-Diabetic Medication Score of Patients with Type 2 Diabetes Mellitus: A Retrospective Study
Conclusion: The present study indicates that 2 weeks of a yoga-based residential program improves blood glucose levels, blood pressure, and medication score in patients with T2DM. However, further randomized controlled studies need to be performed in order to confirm the present findings.Integr Med Int 2017;4:181 –186 (Source: Integrative Medicine International)
Source: Integrative Medicine International - April 4, 2018 Category: Complementary Medicine Source Type: research

The State of Intracellular Molecular Regulators during the Reconvalescence of Community-Acquired Pneumonia under the Influence of Microwaves at 1 GHz
We evaluated the levels of protein p53, retinoblastoma protein (RB), β-catenin, SMAD2, protein kinases AKT and focal adhesion kinase (FAK), and transcription factor CREB using ELISA in mononuclear leukocytes of patients with community-acquired pneumonia on days 15–17 of the disease. The research results showed that the subclinical immune-inflammatory process was c haracterized by a higher content of β-catenin by 19.8%, CREB by 23.3%, RB protein by 14.7%, increased phosphorylation level of protein kinase FAK by 19.8%, АKТ1 at serine-473 by 65.6%, and RB by 13.7%. In the cells, there was a decrease in p53 o...
Source: Integrative Medicine International - February 6, 2018 Category: Complementary Medicine Source Type: research

Cell Death and Induced p53 Expression in Oral Cancer, HeLa, and Bone Marrow Mesenchyme Cells under the Exposure to Noncontact Electric Fields
Conclusion: The high IRS shown in the treated oral cancer and HeLa culture cells may suggest that p53 expression in these culture cells is associated with the cell death mechanism induced by the exposure to noncontact electric fields, and the increased cell death in these culture cells may correlate with the IRS.Integr Med Int 2017;4:161-170 (Source: Integrative Medicine International)
Source: Integrative Medicine International - December 20, 2017 Category: Complementary Medicine Source Type: research

Whitening Efficacy of Tranexamic Acid Cataplasm on Melasma in Chinese Women
Background/Aims: Oral tranexamic acid (TXA) has been reported to be effective for treating melasma. However, the effect of topical TXA on melasma remains controversial. The aim of this study was to assess the effects of topical TXA cataplasm on melasma.Methods: Eighty-four patients with melasma were randomly assigned to a treatment group or a separate control group. They were instructed to apply 2 pieces of cataplasm with or without TXA. The melasma area severity index (MASI), skin color tone scale (SCTS), and area score were evaluated by dermatologists blinded to the treatment.Results: A significant decrease in the MASI a...
Source: Integrative Medicine International - December 20, 2017 Category: Complementary Medicine Source Type: research

Can Yoga-Based Diabetes Management Studies Facilitate Integrative Medicine in India Current Status and Future Directions
Conclusion: The review article opens new paradigms for researchers to evaluate the connection between diabetes and AD through a yoga-based national campaign on diabetes. This paves the way towards the goal of integrative medicine.Integr Med Int 2017;4:125-141 (Source: Integrative Medicine International)
Source: Integrative Medicine International - November 29, 2017 Category: Complementary Medicine Source Type: research

Postural Orthostatic Tachycardia Syndrome (POTS): Assess, Diagnose, and Evaluate for POTS Treatment (ADEPT)
Conclusion: A diagnostic prescreening tool helps to identify patients with POTS so they can be referred for proper treatment, improving their functionality and quality of life, and decreasing the healthcare burden.Integr Med Int 2017;4:142-153 (Source: Integrative Medicine International)
Source: Integrative Medicine International - November 29, 2017 Category: Complementary Medicine Source Type: research

Can Yoga-Based Diabetes Management Studies Facilitate Integrative Medicine in India? Current Status and Future Directions
Conclusion: The review article opens new paradigms for researchers to evaluate the connection between diabetes and AD through a yoga-based national campaign on diabetes. This paves the way towards the goal of integrative medicine.Integr Med Int 2017;4:125-141 (Source: Integrative Medicine International)
Source: Integrative Medicine International - November 28, 2017 Category: Complementary Medicine Source Type: research

Integrative Research of Induction of Pluripotent Stem Cells
This article reviews the development history, clinical application, and problems and prospects of iPSC, and focuses on the application of iPSC in neurological diseases.Integr Med Int 2017;4:115-124 (Source: Integrative Medicine International)
Source: Integrative Medicine International - November 28, 2017 Category: Complementary Medicine Source Type: research

The Pathophysiological Mechanism and Treatment of Secondary Brain Insult of Hypertensive Intracerebral Hemorrhage
This article presents a brief summary of the pathophysiological mechanism and treatment of SBI after HICH.Integr Med Int 2017;4:107-114 (Source: Integrative Medicine International)
Source: Integrative Medicine International - November 28, 2017 Category: Complementary Medicine Source Type: research

Meraque/San Jiao of Eastern Medicine in Comparison with the Mesentery System Presented in Western Medicine
Background: In Persian medicine (PM) and traditional Chinese medicine (TCM), there is an ignored space, namely the Meraque/San Jiao (M/S) space, which in our previous article has been described in detail. Recently, there has been a publication about the mesentery system describing it as a new system with a history of no more than 300 years. According to our previous publications, this is a part of the M/S system, which could represent adipose tissue and vessels. The mesentery and the M/S system can be regarded as one system, except that the mesentery system is a section of the integrated system of M/S with a history of mor...
Source: Integrative Medicine International - November 15, 2017 Category: Complementary Medicine Source Type: research

Dynamic Analysis of Coupled Sawtooth and Rectangle Cellular Neural Networks with Application in HBV Patients' B-Scan Images
Liver damage caused by hepatitis B virus (HBV) infections is diffuse. Live medical images and FibroScan images show that it is inhomogeneous. Modeling and interpreting such phenomena are both important for theoretical research and practical application. The cellular neural networks (CNNs) introduced by Chua and Yang can model widely observed patterns in both nonbiological and biological media. The sawtooth and rectangle (SR) CNN introduced by Chua and colleagues is able to generate SR-shaped patterns for any random-input grayscale patterns, which are also similar to some chronic HBV-infected patients' liver B-scan images. ...
Source: Integrative Medicine International - October 25, 2017 Category: Complementary Medicine Source Type: research

Traditional Chinese Herbs Improve Salivation and Frequent Nighttime Urination in Patients with Amyotrophic Lateral Sclerosis
Conclusion: The much improved parameters of QS, FNU, and ESS for the JPLST group indicate that JPLST may be a potential additional treatment for salivation and FNU in ALS patients. Large-scale multicenter double-blind randomized-control studies are needed to verify the effectiveness of JPLST in improving salivation and FNU in patients with ALS.Integr Med Int 2017;4:31-38 (Source: Integrative Medicine International)
Source: Integrative Medicine International - October 25, 2017 Category: Complementary Medicine Source Type: research

Liver in the Chinese and Western Medicine
Background: The traditional Chinese medicine (TCM) is based on the 5-element theory, which emphasizes the importance of the dynamic balance among the liver, heart, spleen, lung, and kidney. It is quite confusing that the 5 viscera in TCM share the same names with the organs in Western medicine. Spleen is the only viscus that differs most from the modern concept, while the remaining 4 viscera can all find similarities with the corresponding organs in Western medicine; however, the viscus in TCM is always a broader concept.Key Messages: The 5 major functions of the liver in TCM correspond to the nerve-endocrine-immune networ...
Source: Integrative Medicine International - October 25, 2017 Category: Complementary Medicine Source Type: research

Integrative Views of the Heart in Chinese and Western Medicine
There is a general acknowledgement in almost all civilizations that the heart is the most important organ in the human body. Both Chinese medicine and Western traditional medicine have a long history of heart research, but they have developed different points of view based on the basic cognition. Traditional Chinese medicine is good at summarizing the correspondence and relationship between the heart and exterior things. The physiological functions of the heart are governing blood and vessels, controlling the mind, opening into the tongue, manifesting on the face, and so on, while modern Western medicine does well in explo...
Source: Integrative Medicine International - October 25, 2017 Category: Complementary Medicine Source Type: research

Person-Centered Healthcare and Integrated Public Health
The incubation of person-centered healthcare for integrated public health is the focus of this short communication. Here we look at creating an equipoise between culture, medicine, and translational research methods. We propose that these factors can be explored through participatory action research and on-site training of early-career medical professionals. This approach may be one way to build a bridge between trusted tradition and evidence-informed practice. The authors share twelve paths through which integration might occur. They challenge medical professionals to take their places alongside researchers, policy makers...
Source: Integrative Medicine International - October 25, 2017 Category: Complementary Medicine Source Type: research

Fundamentals of Chaos and Self-Organization Theory in Sports
This study provides the most recent data on pedagogical synergy in sports on th e basis of the chaos and self-organization theory. We established the importance of educational and training processes for the structural harmonious organization of natural systems and the cerebral cortex for scientific improvement; additionally we carried out a synergy analysis of physiological bas es of visual and acoustic perceptions which organize themselves on the basis of the interface of the functions of human body and functional activities of the brain.Integr Med Int 2017;4:57-65 (Source: Integrative Medicine International)
Source: Integrative Medicine International - October 25, 2017 Category: Complementary Medicine Source Type: research

Narendra Modi's Citizen-Centered Yoga for Diabetes Management Program: Will the Indian State Install Integrative Medicine in Premier Institutes
Integr Med Int 2017;4:66-68 (Source: Integrative Medicine International)
Source: Integrative Medicine International - October 25, 2017 Category: Complementary Medicine Source Type: research

Yoga: Can It Be Integrated with Treatment of Neuropathic Pain
Background: Neuropathic pain (NP) is a debilitating condition that may result from spinal cord injury (SCI). Nearly 75% of all SCIs result in NP affecting 17,000 new individuals in the United States every year, and an estimated 7-10% of people worldwide. It is caused by damaged or dysfunctional nerve fibers sending aberrant signals to pain centers in the central nervous system causing severe pain that affects daily life and routine. The mechanisms underlying NP are not fully understood, making treatment difficult. Identification of specific molecular pathways that are involved in pain syndromes and finding effective treatm...
Source: Integrative Medicine International - October 25, 2017 Category: Complementary Medicine Source Type: research

Effect of Integrated Yoga Therapy on Arterial Stiffness: A Pilot Study on Young and Older Adults with Obesity
Background/Aims: The studies on the effect of integrated yoga therapy have shown significant results in improving the overall health. However, the effect of integrated yoga therapy on arterial stiffness is not yet established. The aim of the study was to investigate the effect of integrated yoga therapy on arterial stiffness measured at the radial artery.Methods: A total of 18 participants were included in the study. The participants were divided into three groups based on their age and body mass index. There were 5 participants in group 1 who were considered as nonobese, 7 younger adults with obesity were included in grou...
Source: Integrative Medicine International - October 25, 2017 Category: Complementary Medicine Source Type: research

Co-Occurrence of Acromegaly and Hematological Disorders: A Myth or Common Pathogenic Mechanism
Conclusion: In this review, we aim to provide evidence for the correlation between the two disorders.Integr Med Int 2017;4:94-100 (Source: Integrative Medicine International)
Source: Integrative Medicine International - October 25, 2017 Category: Complementary Medicine Source Type: research

Co-Occurrence of Acromegaly and Hematological Disorders: A Myth or Common Pathogenic Mechanism?
Conclusion: In this review, we aim to provide evidence for the correlation between the two disorders.Integr Med Int 2017;4:94-100 (Source: Integrative Medicine International)
Source: Integrative Medicine International - July 20, 2017 Category: Complementary Medicine Source Type: research

Effect of Integrated Yoga Therapy on Arterial Stiffness: A Pilot Study on Young and Older Adults with Obesity
Background/Aims: The studies on the effect of integrated yoga therapy have shown significant results in improving the overall health. However, the effect of integrated yoga therapy on arterial stiffness is not yet established. The aim of the study was to investigate the effect of integrated yoga therapy on arterial stiffness measured at the radial artery.Methods: A total of 18 participants were included in the study. The participants were divided into three groups based on their age and body mass index. There were 5 participants in group 1 who were considered as nonobese, 7 younger adults with obesity were included in grou...
Source: Integrative Medicine International - July 14, 2017 Category: Complementary Medicine Source Type: research

Yoga: Can It Be Integrated with Treatment of Neuropathic Pain
Background: Neuropathic pain (NP) is a debilitating condition that may result from spinal cord injury (SCI). Nearly 75% of all SCIs result in NP affecting 17,000 new individuals in the United States every year, and an estimated 7-10% of people worldwide. It is caused by damaged or dysfunctional nerve fibers sending aberrant signals to pain centers in the central nervous system causing severe pain that affects daily life and routine. The mechanisms underlying NP are not fully understood, making treatment difficult. Identification of specific molecular pathways that are involved in pain syndromes and finding effective treatm...
Source: Integrative Medicine International - July 5, 2017 Category: Complementary Medicine Source Type: research

Yoga: Can It Be Integrated with Treatment of Neuropathic Pain?
Background: Neuropathic pain (NP) is a debilitating condition that may result from spinal cord injury (SCI). Nearly 75% of all SCIs result in NP affecting 17,000 new individuals in the United States every year, and an estimated 7-10% of people worldwide. It is caused by damaged or dysfunctional nerve fibers sending aberrant signals to pain centers in the central nervous system causing severe pain that affects daily life and routine. The mechanisms underlying NP are not fully understood, making treatment difficult. Identification of specific molecular pathways that are involved in pain syndromes and finding effective treatm...
Source: Integrative Medicine International - July 4, 2017 Category: Complementary Medicine Source Type: research

Narendra Modi's Citizen-Centered Yoga for Diabetes Management Program: Will the Indian State Install Integrative Medicine in Premier Institutes?
Integr Med Int 2017;4:66-68 (Source: Integrative Medicine International)
Source: Integrative Medicine International - June 16, 2017 Category: Complementary Medicine Source Type: research

Fundamentals of Chaos and Self-Organization Theory in Sports
This study provides the most recent data on pedagogical synergy in sports on th e basis of the chaos and self-organization theory. We established the importance of educational and training processes for the structural harmonious organization of natural systems and the cerebral cortex for scientific improvement; additionally we carried out a synergy analysis of physiological bas es of visual and acoustic perceptions which organize themselves on the basis of the interface of the functions of human body and functional activities of the brain.Integr Med Int 2017;4:57-65 (Source: Integrative Medicine International)
Source: Integrative Medicine International - April 27, 2017 Category: Complementary Medicine Source Type: research

Person-Centered Healthcare and Integrated Public Health
The incubation of person-centered healthcare for integrated public health is the focus of this short communication. Here we look at creating an equipoise between culture, medicine, and translational research methods. We propose that these factors can be explored through participatory action research and on-site training of early-career medical professionals. This approach may be one way to build a bridge between trusted tradition and evidence-informed practice. The authors share twelve paths through which integration might occur. They challenge medical professionals to take their places alongside researchers, policy makers...
Source: Integrative Medicine International - April 21, 2017 Category: Complementary Medicine Source Type: research

Liver in the Chinese and Western Medicine
Background: The traditional Chinese medicine (TCM) is based on the 5-element theory, which emphasizes the importance of the dynamic balance among the liver, heart, spleen, lung, and kidney. It is quite confusing that the 5 viscera in TCM share the same names with the organs in Western medicine. Spleen is the only viscus that differs most from the modern concept, while the remaining 4 viscera can all find similarities with the corresponding organs in Western medicine; however, the viscus in TCM is always a broader concept.Key Messages: The 5 major functions of the liver in TCM correspond to the nerve-endocrine-immune networ...
Source: Integrative Medicine International - April 11, 2017 Category: Complementary Medicine Source Type: research

Integrative Views of the Heart in Chinese and Western Medicine
There is a general acknowledgement in almost all civilizations that the heart is the most important organ in the human body. Both Chinese medicine and Western traditional medicine have a long history of heart research, but they have developed different points of view based on the basic cognition. Traditional Chinese medicine is good at summarizing the correspondence and relationship between the heart and exterior things. The physiological functions of the heart are governing blood and vessels, controlling the mind, opening into the tongue, manifesting on the face, and so on, while modern Western medicine does well in explo...
Source: Integrative Medicine International - April 11, 2017 Category: Complementary Medicine Source Type: research

Traditional Chinese Herbs Improve Salivation and Frequent Nighttime Urination in Patients with Amyotrophic Lateral Sclerosis
Conclusion: The much improved parameters of QS, FNU, and ESS for the JPLST group indicate that JPLST may be a potential additional treatment for salivation and FNU in ALS patients. Large-scale multicenter double-blind randomized-control studies are needed to verify the effectiveness of JPLST in improving salivation and FNU in patients with ALS.Integr Med Int 2017;4:31-38 (Source: Integrative Medicine International)
Source: Integrative Medicine International - March 30, 2017 Category: Complementary Medicine Source Type: research

Dynamic Analysis of Coupled Sawtooth and Rectangle Cellular Neural Networks with Application in HBV Patients' B-Scan Images
Liver damage caused by hepatitis B virus (HBV) infections is diffuse. Live medical images and FibroScan images show that it is inhomogeneous. Modeling and interpreting such phenomena are both important for theoretical research and practical application. The cellular neural networks (CNNs) introduced by Chua and Yang can model widely observed patterns in both nonbiological and biological media. The sawtooth and rectangle (SR) CNN introduced by Chua and colleagues is able to generate SR-shaped patterns for any random-input grayscale patterns, which are also similar to some chronic HBV-infected patients' liver B-scan images. ...
Source: Integrative Medicine International - March 1, 2017 Category: Complementary Medicine Source Type: research

The Brief Theory of Viscus and Its Manifestations in Traditional Chinese Medicine
Integr Med Int 2017;4:13-18 (Source: Integrative Medicine International)
Source: Integrative Medicine International - February 7, 2017 Category: Complementary Medicine Source Type: research

The Puzzle of the Skin Patterns
Background: The pattern of distribution of skin diseases remains one of the most elusive problems in dermatology, particularly when multiple pathologies are involved and coexistence of patterns is present. Most skin diseases show a predilection for certain body areas and are located in characteristic patterns. Many dermatoses exhibit lesions in a segmental fashion concomitantly with disseminated patterns. Sometimes the sites of predilection are inexplicable.Objectives: The main purpose of this paper is to give an overview on the peculiar arrangement of cutaneous lesions in both congenital and acquired skin disorders as wel...
Source: Integrative Medicine International - December 21, 2016 Category: Complementary Medicine Source Type: research

Advancing the Adoption of Integrative Medicine: A Quick Guide to Publishing Research in < b > < i > Integrative Medicine International < /i > < /b >
Researchers and clinicians in integrative medicine (IM) are well aware that the research and reporting methods they use should be as scientifically rigorous as those used in conventional medicine. To establish the scientific evidence needed to promote the further adoption of traditional medicine (TM) and complementary and alternative medicine (CAM) into healthcare systems worldwide, it is important that doctors of IM publish their findings in English. The English-language, cross-disciplinary journalIntegrative Medicine Internationalaims to publish such work, by focusing on reporting ‘new methods in [TM/CAM] research ...
Source: Integrative Medicine International - October 26, 2016 Category: Complementary Medicine Source Type: research

Indian PM's International Yoga Day 2016 Advocacy: Trends, Advances and Future Perspectives. June 9-12, 2016, Chandigarh, India: Abstracts
Integr Med Int 2016;3:115-131 (Source: Integrative Medicine International)
Source: Integrative Medicine International - October 18, 2016 Category: Complementary Medicine Source Type: research

Indian PM's International Yoga Day 2016 Advocacy: Trends, Advances and Future Perspectives
Integr Med Int 2016;3:113-114 (Source: Integrative Medicine International)
Source: Integrative Medicine International - October 18, 2016 Category: Complementary Medicine Source Type: research

Correlation between Routine Parameters of Digital Rectal Examination and Expressed Prostatic Secretions and Traditional Chinese Medicine Syndromes of Chronic Prostatitis
Objective: To explore and analyze the correlation of routine parameters of digital rectal examination and expressed prostatic secretions (EPS) with traditional Chinese medicine (TCM) syndromes of chronic prostatitis (CP).Methods: According to features of TCM syndromes, 114 CP patients were divided into four groups: group A (syndrome of dampness-heat pouring downward), group B (syndrome of qi stagnation and blood stasis), group C (syndrome of yin deficiency with effulgent fire), and group D (syndrome of kidney yang deficiency). Data collected by digital rectal examination and EPS were divided into different grades according...
Source: Integrative Medicine International - October 14, 2016 Category: Complementary Medicine Source Type: research

Acupuncture Embedding Complication: Second Report of a Rare Case
Conclusions: The current authors believe that this complication is a kind of aseptic inflammation and there is no need for any invasive procedure.Integr Med Int 2016;3:99-105 (Source: Integrative Medicine International)
Source: Integrative Medicine International - October 14, 2016 Category: Complementary Medicine Source Type: research

The Development of Integrative Medicine
Integr Med Int 2016;3:96-98 (Source: Integrative Medicine International)
Source: Integrative Medicine International - October 14, 2016 Category: Complementary Medicine Source Type: research

Evaluation of Movements in Tapping and Tremor from the Viewpoint of the Theory of Chaos and Self-Organization
Chaos in the organization of any human or animal movement has its own parameters in the form of quasi-attractors, and these parameters (quasi-attractors) have a diagnostically significant value. Motor activity of any biological entity in biomechanics consists of a real superposition of voluntary acts (i.e., having a goal and the mechanisms of its implementation) and an obligatory element of chaos when the arbitrary motor activity cannot really be implemented arbitrarily. This paper presents examples of the practical implementation of the parameters of chaos in clinical medicine and their diagnostic value.Integr Med Int 201...
Source: Integrative Medicine International - August 11, 2016 Category: Complementary Medicine Source Type: research

Clinical Effects of a 6-Month Treatment Course of Ibandronate, Vitamin D, and Calcium in Postmenopausal Women from Central America: Results of a Multinational, Prospective Pilot Study
Background/Aims: To explore the effects of ibandronate plus a supplementation of vitamin D and calcium on bone mineral density (BMD) and health-related quality of life (HRQoL) in a sample of postmenopausal women from Central America. Secondarily, factors related to the magnitude of improvements in BMD after treatment were investigated.Methods: Postmenopausal women with idiopathic osteoporosis or at risk of developing it, who were going to start treatment with ibandronate 150 mg once a month plus daily supplementation with vitamin D 400-800 IU and calcium 500-1,000 mg, were followed up for 6 months. BMD, HRQoL (mini-Osteopo...
Source: Integrative Medicine International - August 4, 2016 Category: Complementary Medicine Source Type: research

A Laser Watch for Simultaneous Laser Blood Irradiation and Laser Acupuncture at the Wrist
Conclusion: The laser watch is practicable; however, further research is absolutely necessary before the laser watch is widely used. Integr Med Int 2016;3:75-81 (Source: Integrative Medicine International)
Source: Integrative Medicine International - July 22, 2016 Category: Complementary Medicine Source Type: research

Advancing the Adoption of Integrative Medicine: A Quick Guide to Publishing Research in Integrative Medicine International
Researchers and clinicians in integrative medicine (IM) are well aware that the research and reporting methods they use should be as scientifically rigorous as those used in conventional medicine. To establish the scientific evidence needed to promote the further adoption of traditional medicine (TM) and complementary and alternative medicine (CAM) into healthcare systems worldwide, it is important that doctors of IM publish their findings in English. The English-language, cross-disciplinary journal Integrative Medicine International aims to publish such work, by focusing on reporting ‘new methods in [TM/CAM] researc...
Source: Integrative Medicine International - July 20, 2016 Category: Complementary Medicine Source Type: research

Kidneys in Oriental and Occidental Medicine
Background: Oriental medicine is based on the 5-phase theory, in which the balance among the 5 viscera - the liver, the heart, the spleen, the lung and the kidney - is important. It is confusing that the viscera in Oriental and Occidental medicine have the same name. Out of the 5 viscera in Oriental medicine, it is the spleen that differs most from that in Occidental medicine. It mainly corresponds to the digestive organs and pancreas and has no relation to the spleen in Occidental medicine, a kind of lymph tissue. On the other hand, the concept of each of the other Oriental viscera includes the corresponding viscus in Occ...
Source: Integrative Medicine International - July 14, 2016 Category: Complementary Medicine Source Type: research

Immune Responses Mediated by Th17 Cells in Helicobacter pylori Infection
T helper 17 (Th17) cells are one of the CD4+ T-cell subsets which induce a variety of diseases by secreting IL-17 and other inflammatory factors. After Helicobacter pylori (Hp) infection, cytotoxin-associated gene A and urease subunit B regulate the number of Th17 cells via induction of cell differentiation by infected macrophages, activation of MyD88 and other pathways, and by driving chemokines, which upregulates the number of both Th17 cells and regulatory T cells (Tregs) and switches towards a Treg-type immune response. Meanwhile, Th17 cells also play important roles in the response to Hp infection, participating in th...
Source: Integrative Medicine International - July 8, 2016 Category: Complementary Medicine Source Type: research

Herbal Medicine-Induced Liver Injury in China
Herbal medicine (HM) has been widely used to prevent and treat diseases for thousands of years. However, recent increasing evidence shows that HM-induced liver injury (HILI) is not something to be ignored. In fact, herbal toxicity has always been recognized and emphasized in the long history of Traditional Chinese Medicine. In this article, we analyzed the situation of HILI in China and its risk factors in detail. In addition, the legal regime of the HM industry in contemporary China is introduced. Recently, the mechanisms of HILI have been widely studied, and epidemiological investigations into HILI have been conducted. I...
Source: Integrative Medicine International - May 13, 2016 Category: Complementary Medicine Source Type: research

Targeting ONOO-/HMGB1/MMP-9 Signaling Cascades: Potential for Drug Development from Chinese Medicine to Attenuate Ischemic Brain Injury and Hemorrhagic Transformation Induced by Thrombolytic Treatment
Stroke is the leading cause of death and disability worldwide, and ischemic stroke accounts for more than 85% of the stroke incidence. Tissue plasminogen activator (t-PA) is the only FDA-approved drug for ischemic stroke treatment with a narrow treatment time window of 4.5 h. Hemorrhagic transformation (HT) is a severe complication of delayed t-PA treatment in ischemic stroke. Thus, it is critically important to develop combination therapies to reduce HT and extend the therapeutic time window of t-PA. Current progress suggests that peroxynitrite (ONOO-)/high-mobility group box 1 protein (HMGB1)/matrix metalloproteinase-9 (...
Source: Integrative Medicine International - February 3, 2016 Category: Complementary Medicine Source Type: research