Hydrocele in Pediatric Population.
Authors: Patoulias I, Koutsogiannis E, Panopoulos I, Michou P, Feidantsis T, Patoulias D Abstract Hydrocele is a collection of fluid within the tunica vaginalis. Based upon the etiology and the pathophysiology, it is divided into, the primary and secondary. The primary hydrocele includes the neonatal or the congenital, the communicating and the non-communicating or the closed or the adult type. The secondary hydrocele can develop in the substrate of a pre-existing disease. After systematic and thorough systematic and thorough research of the relevant literature, we aim at describing all the aspects of this entity, ...
Source: Acta Medica: Hradec Kralove - August 13, 2020 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Robotic Management of Fibroids: Discussion of Use, Criteria and Advantages.
Discussion of Use, Criteria and Advantages. Acta Medica (Hradec Kralove). 2020;63(2):63-66 Authors: Gkegkes ID, Iatrakis G, Iavazzo PE, Bakalianou K, Iavazzo C Abstract Fibroids are the most common benign tumors affecting fertility and quality of life. Different methods either definitive or fertility sparing are used for their management by using open, laparoscopic and robotic techniques. This is a narrative review presenting the role and the advantages of robotic surgery in fibroids (myomectomies or hysterectomies). Such a management is effective, safe and feasible in hands of well-trained teams even ...
Source: Acta Medica: Hradec Kralove - August 13, 2020 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Perception of Undergraduate Students at the Faculty of Medicine in Hradec Kr álové Regarding Their Endodontic Education and Suggested Improvements.
CONCLUSIONS: The overall perception of the students was that their endodontic education was sufficient and largely conformed to the guidelines. Insufficient exposure to endodontic practice on patients was identified as a deficiency. There were no significant differences in perceptions between the two study groups. PMID: 32771071 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - August 13, 2020 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Fluoroscopic Epidural Steroid Injection: Pain Relief in Discogenic Sciatica Versus Lumbar Spinal Stenosis. A Study on Middle Eastern Patients.
CONCLUSION: ESI are more effective in patients with Sci than in single level LSS. In multiple level LSS, results are disappointing. PMID: 32771072 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - August 13, 2020 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Duodenal Pressure Necrosis in a Child Caused by a Migrated Percutaneous Endoscopic Gastrostomy.
Authors: Melek J, Štanclová M, Štichhauer R, Rozsíval P, Kopřiva J, Dědková J, Terifajova E, Šedivá E, Dědek P, Skálová S, Bureš J Abstract A two-year-old girl with two weeks of abdominal pain, vomiting, and food refusal, ten months after percutaneous endoscopic gastrostomy insertion because of inadequate peroral intake, was admitted to a tertiary centre hospital. On admission, the extracorporeal part of the gastrostomy was much shortened. X-ray examination revealed migration of the end of the gastrostomy tube with a left-shifted course of the...
Source: Acta Medica: Hradec Kralove - August 13, 2020 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Candida Skull Base Osteomyelitis: a Case Report and Literature Review.
Authors: Krishnamoorthy M, Othman NAN, Hassan NEB, Hitam SB Abstract Skull base osteomyelitis (SBO) also commonly known as malignant otitis externa was first described by Meltzer and Kelemen in 1959. Prior to the advent of the antibiotic era, this disease carried a poor prognosis with significant morbidity. It often proved fatal with mortality rates as high as 50%. Commonly seen in the immunocompromised patients, diabetes mellitus is an important associated comorbidity in the pathophysiologic development of this disease. Treatment is instituted by medical therapy with surgery having a limited role. Surgical interve...
Source: Acta Medica: Hradec Kralove - August 13, 2020 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Pierre Robin Sequence: Diagnostic Difficulties Faced while Differentiating Isolated and Syndromic Forms.
We describe two cases of PRS of Indian ethnicity and describe some of the difficulties that we faced while distinguishing isolated PRS from syndromic PRS. Both cases had a similar clinical presentation. However, one of the cases had a positive family history of congenital deafness and cleft palate, whereas the other case had apparent upper limb anomalies. These facts heightened the suspicion of an associated syndrome. However, based on the available facts and after thorough investigations, a tentative diagnosis of isolated PRS was made for both the patients. Both the cases were managed conservatively and were advised a lon...
Source: Acta Medica: Hradec Kralove - August 13, 2020 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Thyrotoxic Hypokalemic Periodic Paralysis Triggered by Dexamethasone Administration.
Authors: Polamaung W, Kongkit J, Yimnoi P, Boonchaya-Anant P, Snabboon T Abstract Thyrotoxic hypokalemic periodic paralysis (THPP) is a disease characterized by recurrent episodes of muscle weakness due to intracellular potassium shifting in the presence of high levels of thyroid hormone. It occurs more commonly amongst young Asian men with underlying Graves' disease. Attacks are commonly precipitated by ingestion of carbohydrate-rich meals or alcohols, stress or strenuous exercise. Herein, we describe an adult Thai man suffering from a hypokalemic periodic paralysis attack after receiving a dexamethasone injection...
Source: Acta Medica: Hradec Kralove - August 13, 2020 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Melanoma Incidence in Czech Republic, the Relation between Histology, Body Site of Melanoma, and Duration of Lesions.
CONCLUSION: No change in the occurrence of melanoma and in age of melanoma during this period was found. The difference between men and women was not confirmed in histology, but the difference between men and women was confirmed in the body site of lesion and in the length of duration of lesion. No relation between the length of duration of lesions from which melanoma had originated and its histology was confirmed. The relation was confirmed between histology and body site of melanoma. The relation between the body site and the length of duration of previous lesions was confirmed also. The increasing occurrence of melanoma...
Source: Acta Medica: Hradec Kralove - May 20, 2020 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Epidemiology of Melanoma in the Czech Republic in East Bohemia in the Period 2002-2017 and the Effect of the Annual Sunshine Exposure.
CONCLUSION: Our study confirmed that the number of patients with lentigo maligna and melanoma in situ had increased in East Bohemia region in the period of 2002-2017. The number of melanomas of nodular and superficial type does not increase. The total number of melanomas in this period does not increase either. No difference of the age of patients with melanoma nodulare, superficiale, lentigo maligna and melanoma in situ was confirmed. We confirmed no relation of the annual numbers of hours of sunshine to the number of melanoma and to the body site of melanoma. PMID: 32422111 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - May 20, 2020 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Experimental Evaluation of the Impact of Gadolinium Orthovanadate GdVO4:Eu3+ Nanoparticles on the Carrageenan-Induced Intestinal Inflammation.
CONCLUSION: No adverse effects were observed in rats orally exposed to VNPs at a dose of 20 μg/kg during two weeks. Using the experimental model of carrageenan-induced enteritis, it was demonstrated that VNPs at the dose used in our study did not affect the course of intestinal inflammation. PMID: 32422112 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - May 20, 2020 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Comparison of Subthreshold 532 nm Diode Micropulse Laser with Conventional Laser Photocoagulation in the Treatment of Non-Centre Involved Clinically Significant Diabetic Macular Edema.
Authors: Bougatsou P, Panagiotopoulou EK, Gkika M, Dardabounis D, Konstantinidis A, Sideroudi H, Perente I, Labiris G Abstract BACKGROUND: The aim of the study was to investigate the effect of the 532 nm (green) diode subthreshold micropulse laser (SML) in the treatment of non-centre involved clinically significant macular edema (CSME) in comparison to the conventional laser photocoagulation (CLP). METHODS: A total of 60 eyes of patients diagnosed with non-centre involved CSME were randomly divided into two groups. SML photocoagulation was performed in the first group (G1), while CLP in the second one (G2). Cen...
Source: Acta Medica: Hradec Kralove - May 20, 2020 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Association of PAI-1 rs1799889 Polymorphism with Susceptibility to Ischemic Stroke: a Huge Meta-Analysis based on 44 Studies.
CONCLUSIONS: This meta-analysis result suggested that PAI-1 rs1799889 polymorphism was associated with an increased risk of ischemic stroke, especially in Asian and Mixed populations. PMID: 32422114 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - May 20, 2020 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Interdisciplinary Management of Visceral Artery Aneurysms and Visceral Artery Pseudoaneurysms.
Conclusions. The choice of the method of treating visceral artery aneurysms and visceral artery pseudoaneurysms depends on the location, size, anatomic features of the visceral arteries and the clinical course of the disease. Both endovascular and surgical treatment demonstrate good postoperative outcomes. Visceral ischemia is one of the most serious complications in the postoperative period, which can complicate both the diagnosis and the choice of treatment tactics. PMID: 32422115 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - May 20, 2020 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

An Alternative Treatment for Vaginal Cuff Wart: a Case Report.
We present the case of a 54 years old postmenopausal patient with a history of vaginal cuff wart and HPV persistence that we managed in our clinic for 6 months with a mix of curcumin, aloe vera, amla and other natural ingredients. As the patient was found to be intolerant to imiquimod (one of the most common conservative methods of treatment) we attempted the use of curcumin, which was applied to the area of the wart three times per week for 6 months. Both clinical and colposcopical improvement was noted in regular clinic visits with regression of the lesion. The outcome of this case encourages our view that curcumin shoul...
Source: Acta Medica: Hradec Kralove - May 20, 2020 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Penile Degloving and Dorsal Dartos Flap Rotation Surgery in the Management of Severe Isolated Penile Torsion in a 6-Year-Old Boy.
Authors: Zvizdic Z, Milisic E, Vranic S Abstract Penile torsion is a rare congenital anomaly that is usually characterized by a counterclockwise rotation of the penile shaft or glans. Although several surgical techniques for its correction have been proposed, the consensus of choosing the most efficient technique remains controversial. Herein, we report our operational approach that successfully corrected a severe (>90 degrees) isolated penile torsion in the form of penile degloving and dorsal dartos flap rotation surgery. PMID: 32422117 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - May 20, 2020 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Pancreatic Adenocarcinoma: Epidemiology, Role of EUS in Diagnosis, Role of ERCP, Endoscopic Palliation.
Authors: Zar S, Kohoutová D, Bureš J Abstract Pancreatic cancer is the seventh leading cause of cancer deaths worldwide and is associated with a poor survival rate. The vast majority of pancreatic cancers are inoperable at the time of diagnosis. In the absence of metastatic disease, operability depends on the extent of local disease; in particular, the presence or absence of vascular and lymph node involvement. Adequate staging is vital in deciding an appropriate treatment plan. Cross sectional imaging including CT, MRI and PET-CT are commonly used for staging. However, EUS is a useful adjunct for acc...
Source: Acta Medica: Hradec Kralove - February 11, 2020 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Association of IL-6 -174 G > C Polymorphism with Susceptibility to Colorectal Cancer and Gastric Cancer: a Systematic Review and Meta-Analysis.
CONCLUSION: The meta-analysis suggests that IL-6 -174G>C polymorphism was not significantly associated with the increased risk of CRC and GC in overall population. However, the results showed that IL-6 -174G>C polymorphism may be associated with risk of GC in Asians. Further studies including a larger sample size will be necessary to clarify these results. PMID: 32036845 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - February 11, 2020 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Robotic Management of Endometriosis: Discussion of Use, Criteria and Advantages: a Review of the Literature.
Discussion of Use, Criteria and Advantages: a Review of the Literature. Acta Medica (Hradec Kralove). 2019;62(4):147-149 Authors: Gkegkes ID, Iavazzo C, Iatrakis G, Iavazzo PE, Pechlivani F, Antoniou E, Bakalianou K Abstract Endometriosis is a very common benign condition affecting fertility and quality of life. Different methods, either definitive or fertility sparing are used for its management by using open, laparoscopic, and robotic techniques. This is a literature review presenting the role and the advantages of robotic surgery in endometriosis. Such a management is effective, safe, and feasible i...
Source: Acta Medica: Hradec Kralove - February 11, 2020 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Genotype C/C 13910 of the Lactase Gene as a Risk Factor for the Formation of Insulin-Resistant Obesity in Children.
CONCLUSION: The presence of the C/C 13910 genotype of the lactase gene is the main factor formation of insulin resistance in children's obesity. What is known? The genotype C/C 13910 of the lactase gene as a risk factor for the chronic inflammatory process in the body. What is New? Genotype C/C 13910 of the lactase gene as a risk factor for insulin-resistant obesity in children. PMID: 32036847 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - February 11, 2020 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Primary Hyperparathyroidism Manifesting with Severe Hypercalcemia in a Nonagenarian Man: Pitfall of Common Imaging Techniques, Localization by 18F-Choline Positron Emission Tomography/Computed Tomography and Successful Management with Calcimimetics.
Authors: Foppiani L, Bottoni G, Piccardo A Abstract A nonagenarian hypertensive man with chronic kidney disease (CKD) was admitted to the emergency department for gastrointestinal symptoms and worsening symptoms of depression. Severe hypercalcemia (15.3 mg/dL) was found and he was hospitalized. Fluids, loop diuretics and glucocorticoids were administered intravenously, which partially reduced calcium levels over a few days and improved his clinical condition. PTH levels proved increased (306 pg/mL) and 25-OHD levels were reduced; primary hyperparathyroidism (PHPT) was diagnosed. Neck ultrasonography (USG) did not s...
Source: Acta Medica: Hradec Kralove - February 11, 2020 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Mucopolysaccharidosis Type I in Children, a Forgotten Diagnosis Responsible for Undiagnosed Musculoskeletal Complaints: Report of Two Cases.
In this study we described two MPS patients with musculoskeletal complaints who were not diagnosed for a period of time. Although musculoskeletal manifestation are common in a variety of clinical conditions, their presence at low ages or co-occurrence of other manifestations (such as cardiac, respiratory, neurologic, etc.) in multiple systems should prompt evaluation of patients for MPS and other metabolic disorders. The rheumatologists' awareness on MPS should be promoted to achieve timely diagnosis and subsequent early treatment. PMID: 32036849 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - February 11, 2020 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Drug-induced Hemolysis in G6PD Deficiency: an Unusual Presentation of a Common Clinical Condition.
Authors: Padakanti A, Shenoy A, Kamath A, Chakrapani M Abstract Glucose-6-phosphate dehydrogenase (G6PD) deficiency can present a diagnostic dilemma owing to the varying degrees of disease severity and the wide range of precipitating factors. Here, we report a case of a 56-year-old man who presented with signs and symptoms of heart failure and, during the course of treatment, developed intravascular hemolysis. On investigation, he was found to be G6PD deficient. Following discontinuation of the fixed-dose combination of isosorbide dinitrate and hydralazine, the clinical condition of the patient improved, and there ...
Source: Acta Medica: Hradec Kralove - February 11, 2020 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Ultrashort ssDNA in Retinoblastoma Patients Blood Plasma Detected by a Novel High Resolution HPLC Technique: a Preliminary Report.
Authors: Ermakov KV, Bukhvostov AA, Vedenkin AS, Stovbun SV, Dvornikov AS, Kuznetsov DA Abstract A significant population of ultrashort (50-150n) single-stranded DNA fragments were found in exosome-free blood plasma of retinoblastoma patients (6.84 ng mL-1), but not in plasma of healthy donors. An original high resolution HPLC technique has been proposed to reveal and characterize this peculiarity. To solve this task, a novel molecular size exclusion - anion exchange analytical technique was developed. Its applicability to diagnostics and oncogenesis research is quizzed here. PMID: 32036851 [PubMed - in process...
Source: Acta Medica: Hradec Kralove - February 11, 2020 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Foreign Bodies in the Abdominal Area: Review of the Literature.
Authors: Nastoulis E, Karakasi MV, Alexandri M, Thomaidis V, Fiska A, Pavlidis P Abstract The aim of this paper is to update and summarize the relevant literature on the anatomical localization, incidence, and diagnostic and therapeutic approaches to abdominal foreign bodies. A comprehensive review was carried out on recorded cases related to the presence of foreign bodies in the abdominal area throughout the literature. Moreover, the phenomenon was discussed in relation to different patient categories associated with childhood, mental or neurological illness, incarceration, and drug trafficking as well as sexual a...
Source: Acta Medica: Hradec Kralove - November 1, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Rhinogenic Orbital Inflammation - What Has Changed over the Past 50 Years?
Authors: Chrobok V, Pellant A, Mandysová P, Mejzlík J, Dědková J, Čelakovský P Abstract INTRODUCTION: The purpose of the study was to compare the incidence, diagnostics, and treatment of rhinogenic inflammatory complications over the past 50 years. MATERIAL AND METHODS: Retrospective study of 292 patients of ENT department, University hospital: Group A treated from 1966 to 1995, Group B treated from 1996 to 2015. RESULTS: Preseptal inflammation was the most common type (73% vs. 74%), followed by subperiosteal abscess (21% vs. 20%). Surgery was indicated in 35% vs. 37% of the pa...
Source: Acta Medica: Hradec Kralove - November 1, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Monocyte to Lymphocyte Ratio, Neutrophil to Lymphocyte Ratio, and Red Cell Distribution Width are the Associates with Gouty Arthritis.
In this study, we aimed to investigate whether they could be a predictive marker to the gout attack. MATERIAL AND METHODS: A hundred and ten gout patients (male/female, 86/24) and 90 (male/female, 64/26) age-, gender-, and body mass index-matched volunteer controls were included in the study. Blood samples were obtained in the intercritical and attack period of the patients. Hemogram, serum uric acid (SUA), C-reactive protein (CRP), and erythrocyte sedimentation rate (ESR) values were studied. RESULTS: In the attack period NLR (p
Source: Acta Medica: Hradec Kralove - November 1, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Validation of the Slovakian version of Boston Carpal Tunnel Syndrome Questionnaire (BCTSQ).
Authors: Ulbrichtová R, Jakušová V, Švihrová V, Dvorštiaková B, Hudečková H Abstract INTRODUCTION: The most common occupational disease is carpal tunnel syndrome. The aim of this study was to translate and validate the Slovakian version of BCTSQ. METHODS: The original questionnaire was translated into the Slovakian language by two expert translators. Cronbach's alpha coefficient was used to analyze the internal consistency of the questionnaire. Construction validity was evaluated by using Pearson's correlation coefficient and Spearman's rank correlation. ...
Source: Acta Medica: Hradec Kralove - November 1, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Effect of Non-Surgical Periodontal Therapy on the Serum Sialic Acid Levels in Diabetic Patients with Periodontitis.
Authors: Suresh R, Jayachandran P, Fenol A, Biswas R, Krishnan S, Kumar KA, Divakar DD, Vellappally S Abstract Sialic acid (SA), a family of acetylated derivatives of neuraminic acid, an acute phase reactant by itself. It usually occurs as a terminal component at the non-reducing end of carbohydrate chains of glycoproteins and glycolipids. SA participates in multiple physiological functions, such as cell-to-cell interactions, cell migration and proliferation. Diabetes mellitus (DM) is a chronic metabolic disorder characterized by rise in blood glucose level. Periodontitis is a chronic inflammatory disease of the pe...
Source: Acta Medica: Hradec Kralove - November 1, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Fusiform Cervical Mass in a 6-Year Old Boy; Do not Forget the Thymic Cyst.
Authors: Patoulias I, Mitroudi M, Rafailidis V, Feidantsis T, Theocharides C, Kampouridou P, Patoulias D Abstract Cervical thymic cyst is a rare clinical entity, with approximately one hundred cases reported in the literature so far. The purpose of this case report is to highlight some certain features, along with an extensive research of the relevant literature. A 6-year-old boy was admitted to the Otorhinolaryngology Department due to the presence of a left-sided, painless, latero-cervical swelling, first observed by his parents 2 weeks ago. Physical examination revealed a painless, well-delineated mass, with no ...
Source: Acta Medica: Hradec Kralove - November 1, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Myelin Oligodendrocyte Glycoprotein Antibody Associated Transverse Myelitis.
Authors: Chroustová I, Mareš M, Ungermann L, Ehler E Abstract Antibodies against myelin oligodendrocyte glycoprotein cause inflammatory lesions of central myelin - in optic nerves, of the brainstem, and spinal cord. There are characteristic changes of CNS white matter, protein-cytological association in cerebrospinal fluid, MOG IgG antibodies, a very important differential diagnosis and a relatively mild course. PMID: 31663506 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - November 1, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Interactions Between Anti-Vegf Therapy and Antitumor Immunity as a Potential Therapeutic Strategy in Colorectal Cancer.
Authors: Buka D, Dvořák J, Richter I, Škrobánek P, Buchler T, Melichar B Abstract There is a growing corpus of evidence indicating that anti-VEGF therapy may normalize the abnormal tumor vasculature with the potential to re-program the tumor immune microenvironment to a more immunosupportive profile. Tumor vessel normalization increases tumor perfusion, and, consequently, oxygen and nutrient supply, and thus can be assumed to improve the general response to anticancer immunotherapy. The increased antitumor immunity responses seen following anti-VEGF therapy may also be associated with the inhi...
Source: Acta Medica: Hradec Kralove - August 23, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

The Interface Between Psychiatry and Ophthalmology.
CONCLUSIONS: Most studies showed a significant relation between psychiatry and ophthalmology, such as eye symptoms and diseases following long-term use of psychotropics as well as psychiatric symptoms and syndromes in patients with eye disorders. Our review may be beneficial to psychiatrists, ophthalmologists, and, last but not least, the patients themselves. PMID: 31362812 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - August 1, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Non-Recurrent Right Laryngeal Nerve: a Rare Anatomic Variation Encountered During a Total Thyroidectomy.
Authors: Chrysikos D, Sgantzos M, Tsiaoussis J, Noussios G, Troupis T, Protogerou V, Spartalis E, Triantafyllou T, Mariolis-Sapsakos T Abstract The non-recurrent laryngeal nerve (nRLN) is a rare anatomic variation that every head and neck surgeon must be aware of, in order to avoid intraoperative injury which leads to postoperative morbidity. We are reporting a case of a nRLN in a 47 year old female patient with medullary thyroid carcinoma who was surgically treated with total thyroidectomy and lymph node dissection. Both two inferior laryngeal nerves were identified, fully exposed and preserved along their cervica...
Source: Acta Medica: Hradec Kralove - August 1, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Abnormal Persistence of Embryonic Blood Supply of Liver: Anatomist's Delight, Surgeon's Nightmare.
We report a unique case of persistence of embryonic arteries of the liver, wherein, the liver was supplied by five vessels. In addition to the usual right and left hepatic arteries from the hepatic artery proper, the liver received two accessory right hepatic arteries, one from the gastroduodenal artery, while another arising from superior mesenteric artery and an accessory left hepatic artery, from the left gastric artery. The origin of gastroduodenal artery was found to be unusually high and its abnormal anterior course over the common bile duct further added complexity to the hepatobiliary anatomy. The presence of these...
Source: Acta Medica: Hradec Kralove - August 1, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Vulvo-Perineal and Perianal Paget Disease. Radical Excision and Reconstruction with Singapore Flap.
In conclusion, radical surgical excision, often necessitating reconstruction techniques, remains the gold standard of care and further adjuvant treatment should be individualised. PMID: 31362815 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - August 1, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Late-Onset Hypertrophic Pyloric Stenosis in a 14-Weeks-Old Full Term Male Infant.
Authors: Pogorelić Z, Čagalj IČ, Žitko V, Nevešćanin A, Krželj V Abstract BACKGROUND: Hypertrophic pyloric stenosis is the most common cause of gastric outlet obstruction in infants, and classically presents at 2 to 6 weeks of age. Delayed presentation is an extremely rare occurrence after early infancy. CASE REPORT: A 14-weeks-old full term male infant presented with non-bilious vomiting, dehydration and hypocloremic metabolic alkalosis. Abdominal ultrasonography revealed tubular mass 20 mm in lenght. Because of unusual age, diagnosis was confirmed with upper gastrointestinal contrast study. Lapar...
Source: Acta Medica: Hradec Kralove - August 1, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Dependence of Deciduous Tooth Eruption Terms and Tooth Growth Rate on the Weight-Height Index at Birth in Macrosomic Children over the First Year of Life.
Conclusions. The somatometric features of fetal macrosomia suggest the influence on the number of teeth that erupt by a certain age. The data on the deviation from the generally accepted terms of teeth eruption in children born with macrosomia, can be the basis for developing new and improving existing prevention programs aimed at preserving dental health. PMID: 31184300 [PubMed - as supplied by publisher] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - June 13, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Calcemia and Inflammatory Markers in Early-Onset Neonatal Infection.
Authors: Kutílek Š, Vracovská M, Pečenková K, Brožíková H, Pikner R, Fejfarková Z Abstract INTRODUCTION: Ionised hypocalcemia (S-Ca2+) has been repeatedly observed in neonates with sepsis. Our aim was to evaluate total calcemia (S-Ca) and its relationship to laboratory markers of infection. METHODS: We retrospectively evaluated total calcemia (S-Ca) and its relationship to laboratory markers of sepsis/infection (serum levels of C-reactive protein - S-CRP and procalcitonin - S-PCT) in 29 full-term neonates with early-onset neonatal infection hospitalized at our ...
Source: Acta Medica: Hradec Kralove - June 13, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

The Assessment of Serum Drug Levels to Diagnose Non-Adherence in Stable Chronic Heart Failure Patients.
Authors: Pelouch R, Voříšek V, Furmanová V, Solař M Abstract BACKGROUND: The aim of our study was to evaluate the prevalence of drug non-adherence in stable chronic heart failure (CHF) patients using serum drug levels (SDL) assessment. METHODS: CHF patients were prospectively enrolled during scheduled outpatient visit. Except standard procedures an unanticipated blood sampling for the SDL assessment was obtained. Analysis was focused on the prescribed heart failure and antihypertensive medication and was performed by liquid chromatography coupled with mass spectrometry. The patient was la...
Source: Acta Medica: Hradec Kralove - April 25, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Dual Tracer 99mTc-Pertechnetate/99mTc-MIBI Dual-Time-Point SPECT/CT Parathyroid Gland Assessment Regarding to Parathyroid Gland Size and Biochemical Parameters - Two Years Single Imaging Centre Experience.
CONCLUSION: Parathyroid scintigraphy provides high sensitivity and superior specificity in parathyroid adenoma location, nevertheless the diagnostic accuracy tends to decline in smaller adenomas and in less metabolically active parathyroid tissue causing only subtle biochemical changes. 18F-Fluorocholine PET/CT or 3D SPECT/CT subtraction should be a reasonable option for those cases. PMID: 30931889 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - April 2, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Prevalence of Musculoskeletal Disorders Symptoms Among Czech Dental Students. Part 2: The Predictive Value of Digital Assessment.
This article is the second part of an evaluation of musculoskeletal disorders (MSDs) prevalence among dental students. As the majority of complaints are in the back region, there is an endeavor to analyze objectively the disorders in this region. One of the non-invasive and non-radiation methods is the spinal curve mapping using the Spinal Mouse® device (Idiag AG, Fehraltorf, Switzerland). The aim of this study was to determine a correlation between subjectively described complaints and the results of an objective examination of the spine using the Spinal Mouse® device. Information about the participants is given i...
Source: Acta Medica: Hradec Kralove - April 2, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Alteration of Thiol-Disulfide Homeostasis in Fibromyalgia Syndrome.
Authors: Tuzcu A, Baykara RA, Alışık M, Omma A, Acet GK, Dogan E, Cure MC, Duygun F, Cure E, Erel O Abstract BACKGROUND: Fibromyalgia syndrome (FMS) is an extra-articular rheumatological disease, characterized by widespread pain and somatic symptoms. The etiology has not yet been clarified. Oxidative stress may play an important role in FMS etiology. Thiol group is a very strong antioxidant. We aimed to investigate whether thiol/disulfide homeostasis in FMS is altered or not. MATERIAL AND METHODS: A total of 80 female FMS patients and 64 healthy female control individuals were included in this study. Thiol a...
Source: Acta Medica: Hradec Kralove - April 2, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Nightstick Fractures, Outcomes of Operative and Non-Operative Treatment.
CONCLUSION: Satisfactory outcome is to be expected with open reduction and internal fixation. Fractures with less than 50% displacement should be treated on individual bases, considering; age, pre-morbid functional status, co-morbidities, compliance and associated injuries. PMID: 30931892 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - April 2, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Thoracic Radiography Characteristics of Drug Sensitive Tuberculosis and Multi Drug Resistant Tuberculosis: A Study of Indonesian National Tuberculosis Prevalence Survey.
CONCLUSION: Nodule is the only type of lesions that distinguish MDR-TB and DS-TB. Infiltrate, cavity and consolidation were the types of chest radiography lesions on DS-TB, meanwhile, a nodule was the only significant lesion for MDR-TB. PMID: 30931893 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - April 2, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Cytotoxic Effects of Pistacia Atlantica (Baneh) Fruit Extract on Human KB Cancer Cell Line.
Authors: Jaafari-Ashkvandi Z, Shirazi SY, Rezaeifard S, Hamedi A, Erfani N Abstract Plants with anticancer properties are considered as cancer preventive and treatment sources, due to their some biological effects. Apoptosis induction and anti-proliferative effects of Baneh extract on various cancer cell lines have been reported. Hence, this study was designed to evaluate the cytotoxic effects of this fruit on KB and human gingival fibroblast cell lines (HGF). KB and HGF cells were treated with various concentrations of ethanolic Baneh extract and cisplatin as positive control. Cytotoxic activity and apoptosis indu...
Source: Acta Medica: Hradec Kralove - April 2, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Actinomycotic Endomyometritis Associated with a Long-Term Use of Intrauterine Device Lasting for 42 Years.
Authors: Bartoš V, Doboszová J, Sudek M Abstract In women, pelvic actinomycosis is closely associated with prolonged use of the intrauterine devices (IUD). A 70-year old female presented with intermittent blood-stained vaginal discharge. An analysis of her history revealed, she was inserted with an IUD 42 years ago, but it has remained in situ untill now. Curettage of the uterus was done, but an IUD was firmly attached inside the cavity and there was not able to remove it. A biopsy material consisted of the large round and oval granules of filamentous and mycelium-like microorganisms. They showed stro...
Source: Acta Medica: Hradec Kralove - April 2, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Intradural Extramedullary Epidermoid Cyst at the Conus Medullaris Level with Thoracic Syringomyelia: A Case Report.
We present the case of a 3-year-old male who was admitted with paraparesis and urinary retention. Magnetic resonance imaging (MRI) of the spine demonstrated intradural extramedullary lesion, compatible with epidermoid cyst, that at the conus medullaris level and a large syringomyelia extending from T4 to L1 vertebrae. Total microsurgical excision of the cyst was performed. No additional drainage was carried out for the syringomyelic cavity. Histopathological examination verified the diagnosis of the epidermoid cyst. Total excision of the cyst and disappearance of the syringomyelia were observed on MRI at 15 days postoperat...
Source: Acta Medica: Hradec Kralove - April 2, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Patients' Expectations in Lens Extraction Surgery: a Systematic Review.
In conclusion, the final patient's postoperative perception could be affected both by the actual outcome of the operation and by patient preoperative expectations. Ocular and systemic comorbidity, unrealistic expectations, preoperative spectacle independence, the cost of surgery, and a previous cataract surgery as well as the level of health literacy and age could influence preoperative expectations and predict more accurately patient satisfaction. Taking these factors into consideration could allow surgeons to control the expectations with an extensive preoperative counseling. PMID: 30664443 [PubMed - in process] (Sou...
Source: Acta Medica: Hradec Kralove - January 23, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Epidemiological Profile and Antimicrobial Resistance Pattern of Enteric Fever in a Tertiary Care Hospital of North India - a Seven Year Ambispective Study.
CONCLUSION: Enteric-fever is a major public-health problem in India. Emergence of multidrug-resistant, Nalidixic-acid resistant and extremely-drug resistant Salmonella mandates ongoing surveillance for targeted empirical therapy and containment of spread. Repeated epidemics call for water, sanitation, hygiene and vaccination strategies to sustain herd-immunity. PMID: 30664444 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - January 23, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research