The Interface Between Psychiatry and Ophthalmology.
CONCLUSIONS: Most studies showed a significant relation between psychiatry and ophthalmology, such as eye symptoms and diseases following long-term use of psychotropics as well as psychiatric symptoms and syndromes in patients with eye disorders. Our review may be beneficial to psychiatrists, ophthalmologists, and, last but not least, the patients themselves. PMID: 31362812 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - August 1, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Non-Recurrent Right Laryngeal Nerve: a Rare Anatomic Variation Encountered During a Total Thyroidectomy.
Authors: Chrysikos D, Sgantzos M, Tsiaoussis J, Noussios G, Troupis T, Protogerou V, Spartalis E, Triantafyllou T, Mariolis-Sapsakos T Abstract The non-recurrent laryngeal nerve (nRLN) is a rare anatomic variation that every head and neck surgeon must be aware of, in order to avoid intraoperative injury which leads to postoperative morbidity. We are reporting a case of a nRLN in a 47 year old female patient with medullary thyroid carcinoma who was surgically treated with total thyroidectomy and lymph node dissection. Both two inferior laryngeal nerves were identified, fully exposed and preserved along their cervica...
Source: Acta Medica: Hradec Kralove - August 1, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Abnormal Persistence of Embryonic Blood Supply of Liver: Anatomist's Delight, Surgeon's Nightmare.
We report a unique case of persistence of embryonic arteries of the liver, wherein, the liver was supplied by five vessels. In addition to the usual right and left hepatic arteries from the hepatic artery proper, the liver received two accessory right hepatic arteries, one from the gastroduodenal artery, while another arising from superior mesenteric artery and an accessory left hepatic artery, from the left gastric artery. The origin of gastroduodenal artery was found to be unusually high and its abnormal anterior course over the common bile duct further added complexity to the hepatobiliary anatomy. The presence of these...
Source: Acta Medica: Hradec Kralove - August 1, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Vulvo-Perineal and Perianal Paget Disease. Radical Excision and Reconstruction with Singapore Flap.
In conclusion, radical surgical excision, often necessitating reconstruction techniques, remains the gold standard of care and further adjuvant treatment should be individualised. PMID: 31362815 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - August 1, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Late-Onset Hypertrophic Pyloric Stenosis in a 14-Weeks-Old Full Term Male Infant.
Authors: Pogorelić Z, Čagalj IČ, Žitko V, Nevešćanin A, Krželj V Abstract BACKGROUND: Hypertrophic pyloric stenosis is the most common cause of gastric outlet obstruction in infants, and classically presents at 2 to 6 weeks of age. Delayed presentation is an extremely rare occurrence after early infancy. CASE REPORT: A 14-weeks-old full term male infant presented with non-bilious vomiting, dehydration and hypocloremic metabolic alkalosis. Abdominal ultrasonography revealed tubular mass 20 mm in lenght. Because of unusual age, diagnosis was confirmed with upper gastrointestinal contrast study. Lapar...
Source: Acta Medica: Hradec Kralove - August 1, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Dependence of Deciduous Tooth Eruption Terms and Tooth Growth Rate on the Weight-Height Index at Birth in Macrosomic Children over the First Year of Life.
Conclusions. The somatometric features of fetal macrosomia suggest the influence on the number of teeth that erupt by a certain age. The data on the deviation from the generally accepted terms of teeth eruption in children born with macrosomia, can be the basis for developing new and improving existing prevention programs aimed at preserving dental health. PMID: 31184300 [PubMed - as supplied by publisher] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - June 13, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Calcemia and Inflammatory Markers in Early-Onset Neonatal Infection.
Authors: Kutílek Š, Vracovská M, Pečenková K, Brožíková H, Pikner R, Fejfarková Z Abstract INTRODUCTION: Ionised hypocalcemia (S-Ca2+) has been repeatedly observed in neonates with sepsis. Our aim was to evaluate total calcemia (S-Ca) and its relationship to laboratory markers of infection. METHODS: We retrospectively evaluated total calcemia (S-Ca) and its relationship to laboratory markers of sepsis/infection (serum levels of C-reactive protein - S-CRP and procalcitonin - S-PCT) in 29 full-term neonates with early-onset neonatal infection hospitalized at our ...
Source: Acta Medica: Hradec Kralove - June 13, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

The Assessment of Serum Drug Levels to Diagnose Non-Adherence in Stable Chronic Heart Failure Patients.
Authors: Pelouch R, Voříšek V, Furmanová V, Solař M Abstract BACKGROUND: The aim of our study was to evaluate the prevalence of drug non-adherence in stable chronic heart failure (CHF) patients using serum drug levels (SDL) assessment. METHODS: CHF patients were prospectively enrolled during scheduled outpatient visit. Except standard procedures an unanticipated blood sampling for the SDL assessment was obtained. Analysis was focused on the prescribed heart failure and antihypertensive medication and was performed by liquid chromatography coupled with mass spectrometry. The patient was la...
Source: Acta Medica: Hradec Kralove - April 25, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Dual Tracer 99mTc-Pertechnetate/99mTc-MIBI Dual-Time-Point SPECT/CT Parathyroid Gland Assessment Regarding to Parathyroid Gland Size and Biochemical Parameters - Two Years Single Imaging Centre Experience.
CONCLUSION: Parathyroid scintigraphy provides high sensitivity and superior specificity in parathyroid adenoma location, nevertheless the diagnostic accuracy tends to decline in smaller adenomas and in less metabolically active parathyroid tissue causing only subtle biochemical changes. 18F-Fluorocholine PET/CT or 3D SPECT/CT subtraction should be a reasonable option for those cases. PMID: 30931889 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - April 2, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Prevalence of Musculoskeletal Disorders Symptoms Among Czech Dental Students. Part 2: The Predictive Value of Digital Assessment.
This article is the second part of an evaluation of musculoskeletal disorders (MSDs) prevalence among dental students. As the majority of complaints are in the back region, there is an endeavor to analyze objectively the disorders in this region. One of the non-invasive and non-radiation methods is the spinal curve mapping using the Spinal Mouse® device (Idiag AG, Fehraltorf, Switzerland). The aim of this study was to determine a correlation between subjectively described complaints and the results of an objective examination of the spine using the Spinal Mouse® device. Information about the participants is given i...
Source: Acta Medica: Hradec Kralove - April 2, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Alteration of Thiol-Disulfide Homeostasis in Fibromyalgia Syndrome.
Authors: Tuzcu A, Baykara RA, Alışık M, Omma A, Acet GK, Dogan E, Cure MC, Duygun F, Cure E, Erel O Abstract BACKGROUND: Fibromyalgia syndrome (FMS) is an extra-articular rheumatological disease, characterized by widespread pain and somatic symptoms. The etiology has not yet been clarified. Oxidative stress may play an important role in FMS etiology. Thiol group is a very strong antioxidant. We aimed to investigate whether thiol/disulfide homeostasis in FMS is altered or not. MATERIAL AND METHODS: A total of 80 female FMS patients and 64 healthy female control individuals were included in this study. Thiol a...
Source: Acta Medica: Hradec Kralove - April 2, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Nightstick Fractures, Outcomes of Operative and Non-Operative Treatment.
CONCLUSION: Satisfactory outcome is to be expected with open reduction and internal fixation. Fractures with less than 50% displacement should be treated on individual bases, considering; age, pre-morbid functional status, co-morbidities, compliance and associated injuries. PMID: 30931892 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - April 2, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Thoracic Radiography Characteristics of Drug Sensitive Tuberculosis and Multi Drug Resistant Tuberculosis: A Study of Indonesian National Tuberculosis Prevalence Survey.
CONCLUSION: Nodule is the only type of lesions that distinguish MDR-TB and DS-TB. Infiltrate, cavity and consolidation were the types of chest radiography lesions on DS-TB, meanwhile, a nodule was the only significant lesion for MDR-TB. PMID: 30931893 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - April 2, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Cytotoxic Effects of Pistacia Atlantica (Baneh) Fruit Extract on Human KB Cancer Cell Line.
Authors: Jaafari-Ashkvandi Z, Shirazi SY, Rezaeifard S, Hamedi A, Erfani N Abstract Plants with anticancer properties are considered as cancer preventive and treatment sources, due to their some biological effects. Apoptosis induction and anti-proliferative effects of Baneh extract on various cancer cell lines have been reported. Hence, this study was designed to evaluate the cytotoxic effects of this fruit on KB and human gingival fibroblast cell lines (HGF). KB and HGF cells were treated with various concentrations of ethanolic Baneh extract and cisplatin as positive control. Cytotoxic activity and apoptosis indu...
Source: Acta Medica: Hradec Kralove - April 2, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Actinomycotic Endomyometritis Associated with a Long-Term Use of Intrauterine Device Lasting for 42 Years.
Authors: Bartoš V, Doboszová J, Sudek M Abstract In women, pelvic actinomycosis is closely associated with prolonged use of the intrauterine devices (IUD). A 70-year old female presented with intermittent blood-stained vaginal discharge. An analysis of her history revealed, she was inserted with an IUD 42 years ago, but it has remained in situ untill now. Curettage of the uterus was done, but an IUD was firmly attached inside the cavity and there was not able to remove it. A biopsy material consisted of the large round and oval granules of filamentous and mycelium-like microorganisms. They showed stro...
Source: Acta Medica: Hradec Kralove - April 2, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Intradural Extramedullary Epidermoid Cyst at the Conus Medullaris Level with Thoracic Syringomyelia: A Case Report.
We present the case of a 3-year-old male who was admitted with paraparesis and urinary retention. Magnetic resonance imaging (MRI) of the spine demonstrated intradural extramedullary lesion, compatible with epidermoid cyst, that at the conus medullaris level and a large syringomyelia extending from T4 to L1 vertebrae. Total microsurgical excision of the cyst was performed. No additional drainage was carried out for the syringomyelic cavity. Histopathological examination verified the diagnosis of the epidermoid cyst. Total excision of the cyst and disappearance of the syringomyelia were observed on MRI at 15 days postoperat...
Source: Acta Medica: Hradec Kralove - April 2, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Patients' Expectations in Lens Extraction Surgery: a Systematic Review.
In conclusion, the final patient's postoperative perception could be affected both by the actual outcome of the operation and by patient preoperative expectations. Ocular and systemic comorbidity, unrealistic expectations, preoperative spectacle independence, the cost of surgery, and a previous cataract surgery as well as the level of health literacy and age could influence preoperative expectations and predict more accurately patient satisfaction. Taking these factors into consideration could allow surgeons to control the expectations with an extensive preoperative counseling. PMID: 30664443 [PubMed - in process] (Sou...
Source: Acta Medica: Hradec Kralove - January 23, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Epidemiological Profile and Antimicrobial Resistance Pattern of Enteric Fever in a Tertiary Care Hospital of North India - a Seven Year Ambispective Study.
CONCLUSION: Enteric-fever is a major public-health problem in India. Emergence of multidrug-resistant, Nalidixic-acid resistant and extremely-drug resistant Salmonella mandates ongoing surveillance for targeted empirical therapy and containment of spread. Repeated epidemics call for water, sanitation, hygiene and vaccination strategies to sustain herd-immunity. PMID: 30664444 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - January 23, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Prevalence of Musculoskeletal Disorders Symptoms among Czech Dental Students. Part 1: a Questionnaire Survey.
Authors: Kapitán M, Pilbauerová N, Vavřičková L, Šustová Z, Machač S Abstract Musculoskeletal disorders (MSDs) frequently occur among dentists and dental students. The first aim of this study was to gather and analyze information about the prevalence of symptoms of MSDs. The second aim was to determine a correlation between subjectively described complaints and the results of an objective examination of the spine using the Spinal Mouse® device; that part is described in the second section of this article. Dental students of the first, third and fifth years at Charles Univer...
Source: Acta Medica: Hradec Kralove - January 23, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Histological Features of Oral Cavity Mucous Membrane Epithelium in Six-Month-Old Experimental Animals Born with Macrosomia.
We examined the histological features of the mucobuccal fold of oral cavity mucous membrane from the area of the masticatory teeth roots' projection in 6-month-old Wistar Albino Glaxo rats with fetal macrosomia. The animals were divided into groups according to the body weight, the body length, and the Quetelet index at birth. A morphological study was performed using the Leica SP8 AOBS laser scanning confocal microscope and a conventional light (Axiostar, Zeiss) microscopy. Morphometric parameters were used to estimate the degree of acanthosis development in the epithelium of the oral mucosa, which indicates the intensity...
Source: Acta Medica: Hradec Kralove - January 23, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Topiramate Reduces Aortic Cross-Clamping-Induced Lung Injury in Male Rats.
Authors: Kurt A, Kalkan Y, Turut H, Cure MC, Tumkaya L, Cure E Abstract BACKGROUND: Topiramate (TPM) decreases cytokine release and generation of reactive oxygen species (ROS). Cytokine and endothelin-1 (ET-1) secretion and ROS formation play an important role in ischemia-reperfusion (I/R) injury. We aimed to evaluate whether TPM prevents damage occurring in lung tissue during I/R. MATERIALS AND METHODS: A total of 27 Wistar albino rats were divided into three groups of nine. To the I/R group, two hours of ischemia via infrarenal abdominal aorta cross-ligation and then two hours of reperfusion process were appl...
Source: Acta Medica: Hradec Kralove - January 23, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Anaplastic Carcinoma Thyroid in a Young Child - an Extremely Rare Occurrence.
We present a case of 5-yearold child who presented with rapidly progressing thyroid swelling and stridor, for which she underwent emergency tracheostomy and biopsy. Histopathological features were suggestive of ATC and the patient died within two months after diagnosis. ATC, though very rare in childhood, should be kept in the differential diagnoses of rapidly enlarging neck masses in children. To the best of our knowledge, this is the youngest case of ATC reported in literature. PMID: 30664448 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - January 23, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Primary Hepatic Leiomyosarcoma: a Case Report and Review of the Literature.
CONCLUSION: Surgical resection is the most effective among the treatment options. PMID: 30664449 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - January 23, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Pharyngeal Papilloma: a Rare Non-Pulmonary Cause of Hemoptysis.
Authors: Katsenos S, Nikolopoulou M Abstract The most common benign neoplasm of the pharynx is papilloma. It is characterized by bulging brittle lesions, which are pedicled or sessile, whitish-grey or pinkish colour. Progressive hoarseness is the main clinical feature. When the papillomata spread throughout the tracheobronchial tree symptoms such as chronic cough, stridor, dyspnea or acute respiratory distress are mostly present. Hemoptysis as a presenting symptom is exceptionally rare in patients with pharyngeal papillomatosis. Herein, we report a case of pharyngeal papillomatosis in which hemoptysis was the prima...
Source: Acta Medica: Hradec Kralove - January 23, 2019 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Endothelial Dysfunction in Children with Juvenile Psoriatic Arthritis.
Authors: Turoňová L, Kubejová K, Vorčáková K, Ďurdík P, Péčová T, Martinásková K Abstract BACKGROUND: To evaluate the presence of endothelial dysfunction in Slovak children with juvenile psoriatic arthritis in the absence of classic cardiovascular risk factors in order to assess its relationship to the disease activity and disability. METHODS: 25 juvenile psoriatic arthritis patients (JPSA) and 25 healthy controls aged 6-19 years were enrolled into this study. In all subjects vascular measurements over a period of three years (January 2013 - Jan...
Source: Acta Medica: Hradec Kralove - December 15, 2018 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Soluble Tumor Necrosis Factor (TNF)-Like Weak Inducer of Apoptosis (Tweak) Independently Predicts Subclinical Atherosclerosis in Behcet's Disease.
Authors: Icli A, Cure MC, Cure E, Arslan S, Unal M, Sakiz D, Ozucan M, Toker A, Turkmen K, Kucuk A Abstract BACKGROUND: Vasculopathy is a major cause of mortality and morbidity in Behcet's Disease (BD). Subclinical atherosclerosis can even be detected in the early stage of BD. Soluble tumor necrosis factor-like (TNF) weak inducer of apoptosis (TWEAK) is known as a good marker of the inflammation in vascular tree. The aim of this study is to examine the relationship between carotid artery intima-media thickness (cIMT) and serum TWEAK levels in patients with BD. MATERIALS AND METHODS: In line with International B...
Source: Acta Medica: Hradec Kralove - December 15, 2018 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Evaluation of Risk Stratification Markers and Models in Acute Pulmonary Embolism: Rationale and Design of the MARS-PE (Mainz Retrospective Study of Pulmonary Embolism) Study Programme.
Authors: Keller K, Beule J, Balzer JO, Dippold W Abstract An acute pulmonary embolism (PE) is a crucial event in patients' life and connected with serious morbidity and mortality. Regarding a high case-fatality rate, early and accurate risk-stratification is crucial. Risk for mortality and complications are closely related to hemodynamic stability and cardiac adaptations. The currently recommended risk-stratification approach is not overall simple to use and might delay the identification of those patients, who should be monitored more closely and may treated with more aggressive treatment strategies. Additionally,...
Source: Acta Medica: Hradec Kralove - December 15, 2018 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Next Generation Sequencing in Molecular Diagnosis of Lynch Syndrome - a Pilot Study Using New Stratification Criteria.
Authors: Kašubová I, Holubeková V, Janíková K, Váňová B, Sňahničanová Z, Kalman M, Plank L, Lasabová Z Abstract The development of the new technologies such as the next-generation sequencing (NGS) makes more accessible the diagnosis of genetically heterogeneous diseases such as Lynch syndrome (LS). LS is one of the most common hereditary form of colorectal cancer. This autosomal dominant inherited disorder is caused by deleterious germline mutations in one of the mismatch repair (MMR) genes - MLH1, MSH2, MSH6 or PMS2, or the deletion in the EPCAM gen...
Source: Acta Medica: Hradec Kralove - December 15, 2018 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Quality of Life after Reconstructive Surgery for Intestinal Fistulas.
CONCLUSION: Therapy of these patients was and must be complex: it included preparation for surgery at a special metabolic internal site, careful diagnostics of the digestive tract state, suitable surgery and good quality care after the surgery. PMID: 30543515 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - December 15, 2018 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Adult Bochdalek Hernia with Organo-Axial Gastric Volvulus: Misdiagnosed as Hydropneumothorax.
Authors: Arya S, Shahab S, Kumar R, Garg PK Abstract Bochdalek hernia (BH) in an adult may manifest clinically with a myriad of abdominal or chest symptoms or a combination of them. Diagnosis of an adult BH is usually delayed in view of rarity of the lesion and its varied presentation. A 30-year-old adult gentleman presented to us with a left thoracostomy which was draining pus and ingested food particles. The tube thoracostomy had been performed in another hospital for an apparent left hydropneumothorax before he arrived in our hospital. Computed tomography of Chest and abdomen revealed a left diaphragmatic defect...
Source: Acta Medica: Hradec Kralove - December 15, 2018 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Polyneuropathy, Myocardial Dysfunction and Pericardial Effusion Following Duodenal Switch.
In this report we present a case of a patient who had developed polyneuropathy, generalized muscle weakness, Wernicke encephalopathy, myocardial dysfunction and pericardial effusion six years following this operation. He was treated by multivitamins and trace elements with a complete resolution of all of these disturbances. The patient was fully rehabilitated. PMID: 30543517 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - December 15, 2018 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Tunica Vaginalis Thickening, Hemorrhagic Infiltration and Inflammatory Changes in 8 Children with Primary Hydrocele; Reactive Mesothelial Hyperplasia? A Prospective Clinical Study.
Authors: Patoulias D, Chatzopoulos K, Kalogirou M, Rachmani E, Patoulias I Abstract The aim of this study is to describe an entity of primary hydrocele accompanied with fibrosis, thickening and hemorrhagic infiltration of parietal layer of tunica vaginalis (PLTV). During a 4-year period (2011-2014), 94 boys (2.5-14 years old) underwent primary hydrocele repair. Hydrocele was right sided in 55 (58.5 %), left sided in 26 (28.7%) and bilateral in 12 patients (13.8%). Eighty three out of 94 patients (88.30%) had communicating hydrocele and the rest eleven patients (11.7%) had non-communicating. Our case group consists ...
Source: Acta Medica: Hradec Kralove - September 16, 2018 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Electrodermal Activity Monitoring During Painful Stimulation in Sedated Adult Intensive Care Unit Patients: a Pilot Study.
CONCLUSION: EDA measurements are greater to pain stimuli, than cardiovascular, respiratory or even BIS monitoring. These encouraging results suggest that, further studies are needed to better define EDA role in ICU. PMID: 30216182 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - September 16, 2018 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Severe Hypocalcemia and Extreme Elevation of Serum Creatinkinase in a 16-Year Old Boy with Pseudohypoparathyroidism Type Ib.
Authors: Hanulíková K, Černá H, Hasenöhrlová K, Plášilová I, Kutílek Š Abstract Calcium is essential for proper muscular function and metabolism. Myopathy with high creatinkinase activity can be a rare manifestation of hypocalcemia of various origin, such as vitamin D deficiency, hypoparathyroidism, pseudohypoparathyroidism (PHP). 16-year old previously healthy boy was admitted to intensive care unit with convulsions lasting for three minutes and a transient loss of consciousness. Laboratory results revealed severe hypocalcemia (total S-Ca
Source: Acta Medica: Hradec Kralove - September 16, 2018 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

A Long-Term Control of Intramedullary Thoracic Spinal Cord Metastasis from Small Cell Lung Cancer.
We report herein a small cell lung cancer (SCLC) patient with recurrent thoracic ISCM, who was successfully treated with radiotherapy and systemic corticosteroid therapy. A 70-year-old man, who was diagnosed as having SCLC seven months previously, developed thoracic ISCM. Soon after the detection of the lesion, the patient received radiotherapy with systemic corticosteroid therapy. Sensory disturbance in both extremities and neurogenic bladder and bowel dysfunction was recovered. The patient could walk after irradiation again. The patient received additional chemotherapy and survived 20 months after the diagnosis of ISCM r...
Source: Acta Medica: Hradec Kralove - September 16, 2018 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

From Ataxia to Diagnosis of Askin Tumor - a Case Report.
We report a case of a 14-year-old girl, with ataxic gait, cardiopulmonary compensated, without respiratory symptoms, who was referred to our hospital for further examination and treatment of newly discovered tumor of the left hemithorax. After a detailed radiological and laboratory investigation, next step was an extensive thoraco-neurosurgical surgery. After histopathological, cytological and molecular analysis, a diagnosis of Askin tumor was made. PMID: 30216185 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - September 16, 2018 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Abnormal Communication between Lateral Thoracic Artery and Anterior Circumflex Humeral Artery - a Case Report.
Authors: Bhavani PG, Rajprasath R, Kumar DV Abstract Variations in the branching pattern of axillary artery are observed by many anatomists all over the world. A unique bilateral variation in the axillary artery was observed during the routine dissection of the upper limbs on an approximately 65 year old male cadaver. An abnormal communicative channel was observed between lateral thoracic artery and anterior circumflex humeral artery. It passed between the two roots of median nerve. Arterial anomalies in the upper limb are due to defective remodelling of vascular plexus of the upper limb bud during embryogenesis. K...
Source: Acta Medica: Hradec Kralove - September 16, 2018 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Topping Phenomenon with Recurrent Spinal Stenosis and Epidural Fibrosis Prevented with Oxidized Cellulose - a Case Report.
Authors: Hart R Abstract Lumbar spinal stenosis is a condition where the neural structures are compressed in the narrowed spinal canal and often situated only within a single specific segment of the spine, most frequently in the lumbar spine. A case report demonstrates a surgical solution of lumbar spinal stenosis with using oxidized cellulose as a prevention of post-operative adhesions and failed back syndrome. A female patient (68) with a significant pain of the lumbar spine lasting for a number of months due to advanced spondylosis, failing to respond to conservative treatment underwent instrumented, posterolate...
Source: Acta Medica: Hradec Kralove - September 16, 2018 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Cerebral Infarction in Young Marijuana Smokers - Case Reports.
CONCLUSIONS: Cannabinoid use may cause ischemic stroke, especially in the younger age category. Therefore, in these patients we recommend focusing on the history of cannabinoid abuse and carry out toxicological urine tests. PMID: 30216188 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - September 16, 2018 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Cryopreservation of Dental Stem Cells.
The objective of this review is to compare them and highlight their advantages and disadvantages. PMID: 30012243 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - July 18, 2018 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Exhaled Breath Condensate: Pilot Study of the Method and Initial Experience in Healthy Subjects.
Authors: Peterová E, Chládek J, Kohoutová D, Knoblochová V, Morávková P, Vávrová J, Řezáčová M, Bureš J Abstract Analysis of Exhaled breath condensate (EBC) is a re-discovered approach to monitoring the course of the disease and reduce invasive methods of patient investigation. However, the major disadvantage and shortcoming of the EBC is lack of reliable and reproducible standardization of the method. Despite many articles published on EBC, until now there is no clear consensus on whether the analysis of EBC can provide a clue to diagno...
Source: Acta Medica: Hradec Kralove - July 18, 2018 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Immunohistochemical Expression of CDC7 in Dentigerous Cyst, Odontogenic Keratocyst and Radicular Cyst.
This study aimed to evaluate the expression of CDC7 in the most common odontogenic cysts. We evaluated 17 dentigerous cysts, 18 odontogenic keratocysts (OKC) and 13 radicular cysts immunohistochemically. The mean expression of CDC7 was analyzed using ANOVA and Post-HOC methods. All specimens revealed CDC7 expression. Higher expression of CDC7 in OKC and radicular cyst was shown in comparison to dentigerous cyst (P
Source: Acta Medica: Hradec Kralove - July 18, 2018 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Modulation of Rat Liver Regeneration after Partial Hepatectomy by Dietary Cholesterol.
DISCUSSION: Liver regeneration after PH is negatively influenced by CHOL diet. The increased uptake of cholesterol in the liver after PH associated with up-regulation of LDL receptor protein expression suggests preferential use of extrahepatic cholesterol by the liver. PMID: 30012246 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - July 18, 2018 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Giant Uterine Leiomyoma in a Young Woman as an Incidental Finding After a Car Accident: a Case Report.
Authors: Bartoš V, Korec P, Ficek R Abstract Leiomyomas are the most common benign tumor of the uterus. Occasionally, they may reach an extreme dimension. The authors present a case of a 44-year old woman, who suffered a car accident as a driver of personal motor vehicle. At the hospital, a huge tumor mass filling the entire abdominopelvic cavity was incidentally detected. The patient admitted a progressive abdominal enlargement for the last 5 years. An urgent laparotomy was performed, during which a giant, well-demarcated tumor arising from the uterine body had been disclosed. It was completely surgically r...
Source: Acta Medica: Hradec Kralove - July 18, 2018 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

A Bilateral, Non-syndromic, Type III Second Branchial Arch Sinus in a Neonate: a Case Report.
CONCLUSION: - in cases of a bilateral second branchial arch sinus, the branchio-oto-renal (BOR) or branchio-otic (BO) syndromes must be excluded; - ultrasound scan can be used for the thorough evaluation of the sinus anatomic course and the relationship with the adjacent anatomic structures; - rompt diagnosis and early therapeutic intervention, even during neonatal period, ensures an uneventful post-operation course. PMID: 30012248 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - July 18, 2018 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Fountain's Sign as a Diagnostic Key in Acute Idiopathic Scrotal Edema: Case Report and Review of the Literature.
In conclusion, meticulous physical examination along with ultrasonographic examination of the suffering scrotum, especially with the highlighting of fountain's sign with color Doppler, document the diagnosis of AISE. Thus, need for urgent surgical investigation of the suffering scrotum due to diagnostic doubt is limited. PMID: 30012249 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - July 18, 2018 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Sympathetic Nerve Injury in Thyroid Cancer.
Authors: Diamantis E, Farmaki P, Savvanis S, Athanasiadis G, Troupis T, Damaskos C Abstract The double innervation of the thyroid comes from the sympathetic and parasympathetic nervous system. Injury rates during surgery are at 30% but can be minimized by upwardly preparing the thyroid vessels at the level of thyroid capsule. Several factors have been accused of increasing the risk of injury including age and tumor size. Our aim was to investigate of there is indeed any possible correlations between these factors and a possible increase in injury rates following thyroidectomy. Seven studies were included in the met...
Source: Acta Medica: Hradec Kralove - May 5, 2018 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Dose Dependent Prophylactic Efficacy of 6-Chlorotacrine in Soman-Poisoned Mice.
CONCLUSION: These findings demonstrate the important influence of the dose of 6-chlorotacine on its prophylactic efficacy in the case of pharmacological pretreatment of soman poisoning in mice. PMID: 29716679 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - May 5, 2018 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Prevalence of Fibromyalgia Syndrome and Its Correlations with Arrhythmia in Patients with Palpitations.
Authors: Aşkın A, Güvendi E, Özkan A, Şimşek EÇ, Kocabaş U, Tosun A Abstract OBJECTIVE: It is aimed to determine the prevalence of fibromyalgia syndrome (FMS) and its correlations with arrhythmia in patients with palpitations. MATERIAL AND METHODS: Sixty-two patients who underwent electrophysiological study (EPS) due to palpitation complaints in Cardiology department and 40 healthy controls were included in the study. The precise diagnosis of arrhythmia was established using EPS. All participants were screened for FMS using American College of Rheumatology 2010 Fibromyalgia diagnostic crit...
Source: Acta Medica: Hradec Kralove - May 5, 2018 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research

Treatment of Multifocal Multisystem BRAF Positive Langerhans Cell Histiocytosis with Cladribine, Surgery and Allogenic Stem Cell Transplantation.
We describe the difficulties with the diagnosis and treatment of LCH as well as successful treatment with cladribine chemotherapy and allogeneic stem cell transplantation. PMID: 29716681 [PubMed - in process] (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - May 5, 2018 Category: General Medicine Tags: Acta Medica (Hradec Kralove) Source Type: research