Associations of Serum Total Homocysteine Levels with Various Demographic, Clinical and Genetic Characteristics in Healthy Greek Adults
CONCLUSIONS: Serum tHcy levels are influenced by the existence of MTHFR C677T gene polymorphism (mainly 677TT genotype), serum folate and Cbl levels. Individuals with hyperhomocysteinemia should be further investigated for the existence of MTHFR C677T gene polymorphism, with the aim to determine the suitable treatment.PMID:37930095 | DOI:10.14712/18059694.2023.17 (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - November 6, 2023 Category: General Medicine Authors: Elias E Mazokopakis Maria G Papadomanolaki John A Papadakis Source Type: research

COVID-19 Can Unveil Brugada: A Rare Case
Acta Medica (Hradec Kralove). 2023;66(2):68-71. doi: 10.14712/18059694.2023.18.ABSTRACTBrugada syndrome (BRS) is a channelopathy with three characteristic electrocardiogram patterns and an increased risk of sudden cardiac death (SCD), in the absence of gross structural heart disease. Fever is shown to precipitate ventricular arrhythmias in patients with BRS. Here, we report a rare case of Brugada pattern in a patient with Coronavirus Disease 2019 (COVID-19) without fever. A baseline ECG should be considered for patients with COVID-19, even in the absence of fever. COVID-19 by itself may be a factor that can induce Brugada ...
Source: Acta Medica: Hradec Kralove - November 6, 2023 Category: General Medicine Authors: Savalan Babapoor Zachary Port Philip C Wiener Roozbeh Tarighati Rasekhi Ali Babapour Farrokhran Sumeet K Mainigi Source Type: research

Sodium-Hyaluronate Cystic-like Lesion in the Anterior Chamber Following Cataract Surgery: A Case Report
Acta Medica (Hradec Kralove). 2023;66(2):72-74. doi: 10.14712/18059694.2023.19.ABSTRACTThis is a case report describing the uncommon finding of a cystic-like lesion and its management in the anterior chamber of a male patient after cataract surgery.PMID:37930097 | DOI:10.14712/18059694.2023.19 (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - November 6, 2023 Category: General Medicine Authors: Christina Mitsi Minas Bakirtzis Eirini-Kanella Panagiotopoulou Georgios Labiris Source Type: research

Abstracts from 20th International Medical Doctoral Conference (2023) - New Horizons for PhD Students in Medical Research
Acta Medica (Hradec Kralove). 2023;66(2):75-99. doi: 10.14712/18059694.2023.20.ABSTRACTAbstracts from 20th International Medical Doctoral Conference (2023) - New Horizons for PhD Students in Medical Research, Hradec Králové, 29 November - 1 December 2023.PMID:37930098 | DOI:10.14712/18059694.2023.20 (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - November 6, 2023 Category: General Medicine Source Type: research

Non-contact Vital Signs Monitoring in Paediatric Anaesthesia - Current Challenges and Future Direction
Acta Medica (Hradec Kralove). 2023;66(2):39-46. doi: 10.14712/18059694.2023.14.ABSTRACTNon-contact vital sign monitoring is an area of increasing interest in the clinical scenario since it offers advantages over traditional monitoring using leads and wires. These advantages include reduction in transmission of infection and more freedom of movement. Yet there is a paucity of studies available in the clinical setting particularly in paediatric anaesthesia. This scoping review aims to investigate why contactless monitoring, specifically with red-green-blue cameras, is not implemented in mainstream practise. The challenges, d...
Source: Acta Medica: Hradec Kralove - November 6, 2023 Category: General Medicine Authors: Nicole Grech Jean Calleja Agius Stephen Sciberras Neil Micallef Kenneth Camilleri Owen Falzon Source Type: research

Immunological Parameters in Patients Suffering from Atopic Dermatitis and Either Treated or Non-Treated with Dupilumab
CONCLUSION: We demonstrated the difference in the count of white blood cells populations in patients suffering from AD compared with healthy control. There were a differences in the expression of immunoregulatory molecules CD23 and CD200 on B cells in AD patients (either with or without dupilumab therapy) in comparison to healthy controls.PMID:37930093 | DOI:10.14712/18059694.2023.15 (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - November 6, 2023 Category: General Medicine Authors: Petra Boudkov á Jarmila Čelakovská Eva Čermáková Ctirad Andr ýs Jan Krejsek Source Type: research

Evaluation of Diurnal Changes of Mental Fatigue Using a New Portable Device for Visual Cognitive Evoked Potentials
Acta Medica (Hradec Kralove). 2023;66(2):55-60. doi: 10.14712/18059694.2023.16.ABSTRACTIn the age homogenous group of 13 healthy volunteers, we examined visual evoked potentials (VEP) visually evoked cognitive potentials (event-related potentials - ERP) and choice reaction time (CRT) five times during the day (from 10.00 a.m. up to midnight) to verify whether there are significant changes of the measured parameters of the cortical evoked potentials and CRT which might reflect the level of the mental fatigue. The electrophysiological testing was done with the use of a new portable VEP device named "VEPpeak" enabling to perf...
Source: Acta Medica: Hradec Kralove - November 6, 2023 Category: General Medicine Authors: Huey Shin Chua Katrin Ji-In Miller Niha Akhtar Sayyeda Marten Reda Youssef Ibrahim AttaAlla Eithar Osama Eltayeb Babikir Jan Kreml áček Miroslav Kuba Source Type: research

Associations of Serum Total Homocysteine Levels with Various Demographic, Clinical and Genetic Characteristics in Healthy Greek Adults
CONCLUSIONS: Serum tHcy levels are influenced by the existence of MTHFR C677T gene polymorphism (mainly 677TT genotype), serum folate and Cbl levels. Individuals with hyperhomocysteinemia should be further investigated for the existence of MTHFR C677T gene polymorphism, with the aim to determine the suitable treatment.PMID:37930095 | DOI:10.14712/18059694.2023.17 (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - November 6, 2023 Category: General Medicine Authors: Elias E Mazokopakis Maria G Papadomanolaki John A Papadakis Source Type: research

COVID-19 Can Unveil Brugada: A Rare Case
Acta Medica (Hradec Kralove). 2023;66(2):68-71. doi: 10.14712/18059694.2023.18.ABSTRACTBrugada syndrome (BRS) is a channelopathy with three characteristic electrocardiogram patterns and an increased risk of sudden cardiac death (SCD), in the absence of gross structural heart disease. Fever is shown to precipitate ventricular arrhythmias in patients with BRS. Here, we report a rare case of Brugada pattern in a patient with Coronavirus Disease 2019 (COVID-19) without fever. A baseline ECG should be considered for patients with COVID-19, even in the absence of fever. COVID-19 by itself may be a factor that can induce Brugada ...
Source: Acta Medica: Hradec Kralove - November 6, 2023 Category: General Medicine Authors: Savalan Babapoor Zachary Port Philip C Wiener Roozbeh Tarighati Rasekhi Ali Babapour Farrokhran Sumeet K Mainigi Source Type: research

Sodium-Hyaluronate Cystic-like Lesion in the Anterior Chamber Following Cataract Surgery: A Case Report
Acta Medica (Hradec Kralove). 2023;66(2):72-74. doi: 10.14712/18059694.2023.19.ABSTRACTThis is a case report describing the uncommon finding of a cystic-like lesion and its management in the anterior chamber of a male patient after cataract surgery.PMID:37930097 | DOI:10.14712/18059694.2023.19 (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - November 6, 2023 Category: General Medicine Authors: Christina Mitsi Minas Bakirtzis Eirini-Kanella Panagiotopoulou Georgios Labiris Source Type: research

Abstracts from 20th International Medical Doctoral Conference (2023) - New Horizons for PhD Students in Medical Research
Acta Medica (Hradec Kralove). 2023;66(2):75-99. doi: 10.14712/18059694.2023.20.ABSTRACTAbstracts from 20th International Medical Doctoral Conference (2023) - New Horizons for PhD Students in Medical Research, Hradec Králové, 29 November - 1 December 2023.PMID:37930098 | DOI:10.14712/18059694.2023.20 (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - November 6, 2023 Category: General Medicine Source Type: research

Non-contact Vital Signs Monitoring in Paediatric Anaesthesia - Current Challenges and Future Direction
Acta Medica (Hradec Kralove). 2023;66(2):39-46. doi: 10.14712/18059694.2023.14.ABSTRACTNon-contact vital sign monitoring is an area of increasing interest in the clinical scenario since it offers advantages over traditional monitoring using leads and wires. These advantages include reduction in transmission of infection and more freedom of movement. Yet there is a paucity of studies available in the clinical setting particularly in paediatric anaesthesia. This scoping review aims to investigate why contactless monitoring, specifically with red-green-blue cameras, is not implemented in mainstream practise. The challenges, d...
Source: Acta Medica: Hradec Kralove - November 6, 2023 Category: General Medicine Authors: Nicole Grech Jean Calleja Agius Stephen Sciberras Neil Micallef Kenneth Camilleri Owen Falzon Source Type: research

Immunological Parameters in Patients Suffering from Atopic Dermatitis and Either Treated or Non-Treated with Dupilumab
CONCLUSION: We demonstrated the difference in the count of white blood cells populations in patients suffering from AD compared with healthy control. There were a differences in the expression of immunoregulatory molecules CD23 and CD200 on B cells in AD patients (either with or without dupilumab therapy) in comparison to healthy controls.PMID:37930093 | DOI:10.14712/18059694.2023.15 (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - November 6, 2023 Category: General Medicine Authors: Petra Boudkov á Jarmila Čelakovská Eva Čermáková Ctirad Andr ýs Jan Krejsek Source Type: research

Evaluation of Diurnal Changes of Mental Fatigue Using a New Portable Device for Visual Cognitive Evoked Potentials
Acta Medica (Hradec Kralove). 2023;66(2):55-60. doi: 10.14712/18059694.2023.16.ABSTRACTIn the age homogenous group of 13 healthy volunteers, we examined visual evoked potentials (VEP) visually evoked cognitive potentials (event-related potentials - ERP) and choice reaction time (CRT) five times during the day (from 10.00 a.m. up to midnight) to verify whether there are significant changes of the measured parameters of the cortical evoked potentials and CRT which might reflect the level of the mental fatigue. The electrophysiological testing was done with the use of a new portable VEP device named "VEPpeak" enabling to perf...
Source: Acta Medica: Hradec Kralove - November 6, 2023 Category: General Medicine Authors: Huey Shin Chua Katrin Ji-In Miller Niha Akhtar Sayyeda Marten Reda Youssef Ibrahim AttaAlla Eithar Osama Eltayeb Babikir Jan Kreml áček Miroslav Kuba Source Type: research

Associations of Serum Total Homocysteine Levels with Various Demographic, Clinical and Genetic Characteristics in Healthy Greek Adults
CONCLUSIONS: Serum tHcy levels are influenced by the existence of MTHFR C677T gene polymorphism (mainly 677TT genotype), serum folate and Cbl levels. Individuals with hyperhomocysteinemia should be further investigated for the existence of MTHFR C677T gene polymorphism, with the aim to determine the suitable treatment.PMID:37930095 | DOI:10.14712/18059694.2023.17 (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - November 6, 2023 Category: General Medicine Authors: Elias E Mazokopakis Maria G Papadomanolaki John A Papadakis Source Type: research